Temat: ASFV - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Comparative analysis of CpG islands in two genotypes of African swine fever virus
Autorzy:: Yu, Y.-Y.
X, M.-S.
Liu, Q.
Powiązania:: https://bibliotekanauki.pl/articles/16539329.pdf
Data publikacji:: 2022
Wydawca:: Polska Akademia Nauk. Czasopisma i Monografie PAN
Tematy:: African Swine Fever Virus (ASFV)
genotype
DNA methylation
CpG island
Opis:: African swine fever (ASF) is an acute, hemorrhagic, and devastating viral infectious disease that causes important economic losses to the swine industry. Currently, there are no effective vaccines or drugs available. Epigenetic mechanisms, especially cytosine methylation of cytosine-phosphate-guanine (CpG) islands, have a significant impact on the life cycle of several viruses. Hence, drugs targeting DNA methylation may potentially be used for the treatment of ASF. Here, we selected the inner core, core shell, inner membrane, capsid, and external envelope membrane, to analyze the characteristics of CpG islands in the ASF virus (ASFV) genomes. Furthermore, we analyzed the promoters and CpG islands in the upstream regions of these genes. Results showed that the CpG islands of seven genes were conserved in the genomes of two genotype of ASFV strains, whereas the CpG islands of other genes were relatively conserved (ASFV strains differed mainly in the quantity of CpG islands). The different distribution of CpG islands in the genomes of different ASFV strains may affect their methylation status, which may in turn affect the regulation of viral gene expression, leading to different clinical outcomes. In addition, the predicted promoter regions based on the upstream sequences of most genes overlapped with CpG island positions. Methylation of the binding sites of the promoter regions inhibits the binding of the transcription factors to the promoters, thus inhibiting the activation of the promoters and limiting the synthesis of viral proteins. The results of this study provide a basis for exploring new antiviral therapeutic strategies from an epigenetic perspective.
Źródło:: Polish Journal of Veterinary Sciences; 2022, 25, 3; 455-462
1505-1773
Pojawia się w:: Polish Journal of Veterinary Sciences
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Pathomorphology of the brain in the acute form of African swine fever
Autorzy:: Karalyan, Zaven A.
Sargsyan, Mariam A.
Arzumanyan, Hranush H.
Kotsinyan, Armen A.
Hakobyan, Lina H.
Karalova, Elena M.
Voskanyan, Henrih E.
Powiązania:: https://bibliotekanauki.pl/articles/972144.pdf
Data publikacji:: 2017
Wydawca:: Polskie Towarzystwo Parazytologiczne
Tematy:: African swine fever virus (ASFV)
subdural hematomas
cerebral edema
lymphocytic infiltration
viremia
Opis:: The brains of 10 infected pigs were examined for histopathology and presence of African swine fever virus (ASFV) DNA ASFV infection induces inflamed meninges, cerebral edema and vascular thrombosis, as well as subdural hematomas. Slight tension in the dura mater, flattening of the gyri and narrowing of the sulci were also observed at four days post infection (dpi). Enlarged perivascular spaces were detected for most vessels of the brain after three to four dpi. Considerable lymphocytic infiltration of the brain tissue was observed at the terminal stage of disease. ASFV was present in all investigated areas of brain beginning from three to four dpi. The isolated virus do not differ from the used in present study Georgia 2007 strain.
Źródło:: Annals of Parasitology; 2017, 63, 4; 347-352
0043-5163
Pojawia się w:: Annals of Parasitology
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: Wild boar as the most important reservoir and vector of transmission of the African swine fever virus; why do we have to restrict their population
Autorzy:: Pejsak, Zygmunt
Truszczyński, Marian
Powiązania:: https://bibliotekanauki.pl/articles/704203.pdf
Data publikacji:: 2019
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: African swine fever
wild boar
reservoir of ASFV
control of ASF transmission
Opis:: Basing on Polish experience of about 5 years (since the presence of the African swine fever (ASF) in this country, starting from February 17th, 2014) and in accordance with literature the importance of the disease in wild boar is charaterised. ASF belongs to the most dangerous, very contagious diseases occurring in domestic swine and wild boar in Eurasia. In Europe, including Russia, Ukraine, Belarus, Lithuania, Latvia, Estonia, Poland, Romania, Hungary, Bulgaria, Czech Republic and Belgium ASF is existing at present and was diagnosed for short time in the frame of the Eurasian pandemy. There is a serious concern of spreading of the virus of ASF (ASFV) to other countries of Europe, not only by wild boar. However the reservoir of ASFV in this animal is playing a very important role in the maintenance of the virus and infection of pigs. Long lasting existence of ASFV in the environmnent is connected with the very high resistance to antiviral environmental factors. Following the lack of an effective immunogenic vaccine against ASF the disease can only be controlled by administrative measures. Additionally the important and recommended procedure is the significant reduction of the wild boar population. Probability of eradication of ASFV from wild boar is increased after adding quick carcass removal simultaneously by respecting biosecurity rules. If effectively implemented, fencing is more useful to delineating zones rather than adding substantially to increased efficiency of ASF control. However, segments of fencing will be particularly usefull in theses areas, where carcasses removal or intensive hunting is difficult to implement.
Źródło:: Nauka; 2019, 1
1231-8515
Pojawia się w:: Nauka
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 4.

Tytuł:: Choroba jako zjawisko społeczne. Analiza walki z afrykańskim pomorem świń
Disease as a social phenomenon: an analysis of the fight against African swine fever
Autorzy:: Mamzer, Hanna
Powiązania:: https://bibliotekanauki.pl/articles/1037656.pdf
Data publikacji:: 2020-06-30
Wydawca:: Uniwersytet im. Adama Mickiewicza w Poznaniu
Tematy:: ASFV
African swine fever
manipulation
boar
biosecurity
ASF
Afrykański pomór świń
manipulacja
dzik
bioasekuracja
Opis:: Afrykański pomór świń jest bezsprzecznie niebezpieczną chorobą dla świń, dzików i świniodzików. Przynosi znaczące straty gospodarcze. Wydaje się jednak, że walka z chorobą jest wykorzystywana w Polsce do celów, które można określić jako rodzaj reżyserii społecznej. Wdrażane w Polsce rozwiązania eksterminacji dzików nie stanowią skutecznej metody walki z chorobą. Z kolei bioasekuracja, wskazywana jako najskuteczniejsza metoda zapobiegania rozprzestrzeniania się wirusa, nie jest promowana. Szersza, socjokulturowa analiza wykorzystania dyskursu o ASF w generowaniu społecznych napięć wskazuje, że zjawisko jest wieloaspektowe i nie tak proste, jak mogłoby się wydawać.
African swine fever is undoubtedly an extremely dangerous disease for swine and boars. It also causes major economic loss. However, in Poland the fight against the disease seems to have been used as an of instrument of social engineering. The solutions introduced in Poland – such as the extermination of the population of wild boars – will not provide the expected level of biosecurity. Methods that are recommended by experts worldwide focus on biosecurity, but this measure is not successfully enforced in Poland. A wider, socio-cultural analysis of how discourses related to ASFV and other diseases are used reveals that this is very complex phenomena.
Źródło:: Ruch Prawniczy, Ekonomiczny i Socjologiczny; 2020, 82, 2; 281-297
0035-9629
2543-9170
Pojawia się w:: Ruch Prawniczy, Ekonomiczny i Socjologiczny
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 5.

Tytuł:: Virucidal effect of chosen disinfectants against African swine fever virus (ASFV) – preliminary studies
Autorzy:: Juszkiewicz, M.
Walczak, M.
Mazur-Panasiuk, N.
Woźniakowski, G.
Powiązania:: https://bibliotekanauki.pl/articles/2087427.pdf
Data publikacji:: 2019
Wydawca:: Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:: African swine fever (ASF)
African swine fever virus (ASFV)
disinfection
biosecurity
virucidal effects
Źródło:: Polish Journal of Veterinary Sciences; 2019, 4; 777-780
1505-1773
Pojawia się w:: Polish Journal of Veterinary Sciences
Dostawca treści:: Biblioteka Nauki

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