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    Wyświetlanie 1-9 z 9
    Tytuł:
    Transporter protein and drug resistance of Trypanosoma
    Autorzy:
    Medina, N.P.
    Mingala, C.N.
    Powiązania:
    https://bibliotekanauki.pl/articles/6696.pdf
    Data publikacji:
    2016
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Opis:
    Trypanosoma infection is one of the most important infections in livestock and humans. One of the main problems of its therapeutic control and treatment is the resurgence of drug resistance. One of the most studied causes of such resistance is the function of its adenosine transporter gene. A trypanosomal gene TbAT1 from Trypanosoma brucei has been cloned in yeast to demonstrate its function in the transport of adenosine and trypanocidal agents. Drug resistant trypanosomes showed a defective TbAT1 variant; furthermore, deletion of the gene and set point mutations in the transporter gene has been demonstrated from isolates from relapse patients. The molecular understanding of the mechanism of action trypanocidal agents and function of transporter gene can lead to control of drug resistance of Trypanosomes.
    Źródło:
    Annals of Parasitology; 2016, 62, 1
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Hormon antymullerowski (AMH) jako marker pozyskiwania zarodków przeżuwaczy
    Anti-Mullerian hormone as a marker of embryo production in ruminants
    Autorzy:
    Soquila, S.S.
    Mingala, C.N.
    Powiązania:
    https://bibliotekanauki.pl/articles/843200.pdf
    Data publikacji:
    2017
    Wydawca:
    Polskie Towarzystwo Zootechniczne
    Tematy:
    rozrod zwierzat
    biotechnologia rozrodu
    hormon antymullerowski
    markery hormonalne
    superowulacja
    transplantacja zarodkow
    program MOET
    Źródło:
    Roczniki Naukowe Polskiego Towarzystwa Zootechnicznego; 2017, 13, 4
    1733-7305
    Pojawia się w:
    Roczniki Naukowe Polskiego Towarzystwa Zootechnicznego
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Detection of Cryptosporidium parvum DNA in fecal samples of infected cattle (Bos indicus) and water buffaloes (Bubalus bubalis) in the Philippines using loop-mediated isothermal amplification method
    Autorzy:
    Domingo, C.Y.J.
    Pascual, H.G.
    Mingala, C.N.
    Powiązania:
    https://bibliotekanauki.pl/articles/5598.pdf
    Data publikacji:
    2018
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Źródło:
    Annals of Parasitology; 2018, 64, 4
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Molecular identification of Buxtonella sulcata from associated-diarrhea in water buffaloes (Bubalus bubalis) in the Philippines
    Autorzy:
    Dianso, J.A.
    Garcia, G.G.
    Belotindos, L.P.
    Mingala, C.N.
    Powiązania:
    https://bibliotekanauki.pl/articles/5920.pdf
    Data publikacji:
    2018
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Źródło:
    Annals of Parasitology; 2018, 64, 2
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    A comparison of FLOTAC and CFF techniques in detecting gastrointestinal parasites in water buffaloes (Bubalus bubalis)
    Autorzy:
    Salvador, R.T.
    Abalos, R.P.
    Ruba, A.M.
    Mingala, C.N.
    Powiązania:
    https://bibliotekanauki.pl/articles/5746.pdf
    Data publikacji:
    2014
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    parasitism
    FLOTAC technique
    CFF technique
    detection
    gastrointestinal parasite
    parasite
    water buffalo
    Bubalus bubalis
    nematode
    prevalence
    Opis:
    The objective of the study was to compare the usefulness of FLOTAC and centrifugal fecal flotation (CFF) techniques. More specifically, the taxonomic classes (Nematoda and Cestoda) of endoparasites present in fecal samples of buffaloes are identified, the sensitivity and specificity of FLOTAC relative to CFF are calculated, and the agreement of both techniques is evaluated using Kappa statistics. Fresh fecal samples from 220 buffaloes in 10 municipalities were collected. Sheather’s sugar was used as a flotation solution for both the FLOTAC and CFF techniques. Of the 220 animals, 109 samples were nematode positive and 111 samples were nematode negative according to the FLOTAC technique, while 74 were found to be positive and 146 negative according to the CFF technique. No cestodes were detected by either technique. The calculated sensitivity for FLOTAC is 89.19% and its specificity is 70.55%. Kappa statistics revealed moderate agreement (k=0.535) between the two techniques in detecting nematodes. The prevalence observed based on FLOTAC and CFF test were 49.54% (109/220; 95% CI: 47.75–56.34) and 33.64% (72/220; 95% CI: 27.42–40.3), respectively.
    Źródło:
    Annals of Parasitology; 2014, 60, 2
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The prevalence of Ehrlichia canis, Anaplasma platys and Babesia spp. in dogs in Nueva Ecija, Philippines based on multiplex polymerase chain reaction (mPCR) assay
    Autorzy:
    Corales, J.M.I.
    Viloria, V.V.
    Venturina, V.M.
    Mingala, C.N.
    Powiązania:
    https://bibliotekanauki.pl/articles/6624.pdf
    Data publikacji:
    2014
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    prevalence
    Ehrlichia canis
    Anaplasma platys
    Babesia
    dog
    tick-borne disease
    Nueva Ecija province
    Philippines
    multiplex polymerase chain reaction
    Opis:
    The aim of the study was to determine the prevalence of Ehrlichia canis, Anaplasma platys and Babesia spp. in dogs. It describes the practice of veterinarians in detecting tick-borne diseases in Nueva Ecija, Philippines. Seventy blood samples were collected and were subjected to multiplex PCR for the detection of E. canis, Babesia spp. and A. platys. The prevalence of babesiosis is the highest in Cabanatuan City (2/10), while a 10% prevalence (1/10) was observed in Science City of Muñoz, Talavera and Sta. Rosa. E. canis were only detected in Cabanatuan City. However, no anaplasmosis was detected in any area. The prevalence of babesiosis and ehrlichiosis in Nueva Ecija is 7.14% (5/70) and 2.85% (2/70) respectively. In addition, 70% (7/10) of the Nueva Ecija veterinary practitioners encountered cases of suspected ehrlichiosis in their practice. The diagnosis of ehrlichiosis is based primarily on presented clinical signs and complete blood counts, which include a platelet count. Of the 10 respondents, half utilized test kits while 90% interpreted blood samples. Meanwhile, only 60% of the respondents used an ELISA test kit for ehrlichiosis. For some practitioners, the main reason for not utilizing a kit is the high cost. None of the respondents had previously attended cases of suspected anaplasmosis. Only one respondent diagnosed a case of babesiosis by blood smear microscopy.
    Źródło:
    Annals of Parasitology; 2014, 60, 4
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Evidence of Fasciola spp. resistance to albendazole, triclabendazole and bromofenofos in water buffaloes (Bubalus bubalis)
    Autorzy:
    Venturina, V.M.
    Alejandro, A.F.
    Baltazar, C.P.
    Abes, N.S.
    Mingala, C.N.
    Powiązania:
    https://bibliotekanauki.pl/articles/6105.pdf
    Data publikacji:
    2015
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Tematy:
    evidence
    Fasciola
    fasciolosis
    resistance
    albendazole
    triclabendazole
    bromofenofos
    water buffalo
    Bubalus bubalis
    Opis:
    Fasciolosis caused by Fasciola spp. is considered the most important helminth infection of ruminants in tropical countries. Anthelmintic resistance has become a global concern. This study compared the efficacy of the commonly used anthelmintics, determined the toxicity level and any indication of resistance. Thirty two water buffaloes naturally-infected with Fasciola spp. were used to determine the efficacy of triclabendazole (TBZ), albendazole (ABZ), and bromofenofos (BRO) using Fecal Egg Count Reduction Test (FECRT). To test the toxicity of the drugs given, serum glutamic-pyruvic transaminase (SGPT) was evaluated before and within one week after treatment. One dose administration of ABZ registered an efficacy of 79.17%, 73.33% for TBZ and 70.83% for BRO. Efficacy in two dosetreatment group was 83.33% for both BRO and ABZ, and 90.00% for TBZ. Two dose-treatment was effective for TBZ (90%), ineffective for BRO and ABZ. SGPT levels were not significantly different between pre-treatment and posttreatment across all treatments. Giving one or two doses of anthelmintics, at one month interval, does not increase the efficacy of the three drugs tested. The study also implies that anthelmintic resistance may have developed in the animals.
    Źródło:
    Annals of Parasitology; 2015, 61, 4
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Characterization of drug resistance-associated TevAT1 gene of Trypanosoma evansi from Philippine water buffaloes (Bubalus bubalis)
    Autorzy:
    Mingala, C.N.
    Pasag, A.C.P.
    Salinas, M.B.S.
    Balbin, M.M.
    Villanueva, M.A.
    Powiązania:
    https://bibliotekanauki.pl/articles/5876.pdf
    Data publikacji:
    2019
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Źródło:
    Annals of Parasitology; 2019, 65, 4
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    A field trial of recombinant Schistosoma japonicum paramyosin as a potential vaccine in naturally-infected water buffaloes
    Autorzy:
    Jiz II, M.A.L.
    Mingala, C.N.
    Lopez, I.F.M.
    Chua, M.
    Gabonada Jr., F.G.
    Acosta, L.P.
    Wu, H.
    Kurtis, J.D.
    Powiązania:
    https://bibliotekanauki.pl/articles/6326.pdf
    Data publikacji:
    2016
    Wydawca:
    Polskie Towarzystwo Parazytologiczne
    Opis:
    The overall aims of this project are to assess the safety and immunogenicity of the Schistosoma japonicum vaccine paramyosin among water buffaloes residing in endemic areas. The study was conducted in four villages in Leyte, the Philippines, an area highly endemic for schistosomiasis japonica. One hundred and fifteen (N=115) animals provided baseline stool samples for coprologic examination, with preliminary results using FLOTAC showing a 10% prevalence of schistosomiasis. Forty-nine (N=49) animals consented to treatment with 25 mg/kg Praziquantel, and 40, 36 and 32 animals consented to the first, second and third dose of the paramyosin vaccine, respectively. The safety trial involved the first 20 animals and included skin testing, vaccination, anaphylaxis monitoring, as well as hematology and serum chemistry analysis. Skin tests revealed that only three out of 20 animals exhibited redness at the injection site, with none greater than 1 cm. None of the animals exhibited anaphylaxis, and all hematology and serum chemistry markers were within normal range or were similar to pre-vaccination levels. None of the 40 animals administered with the first dose exhibited anaphylaxis, nor any of the subsequent vaccine doses. Immunogenicity assessment of sera collected prior to every vaccination and one month after the last dose showed that the paramyosin vaccine induced robust antibody responses to all animals, as assessed by ELISA. The cytokine levels of whole blood culture supernatants will be further assessed. Our findings demonstrate that the S. japonicum paramyosin vaccine is a safe, well-tolerated and immunogenic treatment among water buffalos residing in endemic areas.
    Źródło:
    Annals of Parasitology; 2016, 62, 4
    0043-5163
    Pojawia się w:
    Annals of Parasitology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-9 z 9

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