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Wyszukujesz frazę "calcium-binding proteins" wg kryterium: Wszystkie pola


Wyświetlanie 1-8 z 8
Tytuł:
The influence of bilberry fruit on memory and the expression of parvalbumin in the rat hippocampus
Autorzy:
Borowiec, K.
Matysek, M.
Szwajgier, D.
Biała, G.
Kruk-Słomka, M.
Szalak, R.
Ziętek, J.
Arciszewski, M.B.
Targoński, Z.
Powiązania:
https://bibliotekanauki.pl/articles/2087496.pdf
Data publikacji:
2019
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
bilberry
calcium-binding proteins
hippocampus
memory
rat
Źródło:
Polish Journal of Veterinary Sciences; 2019, 3; 481-487
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Ca2+differently affects hydrophobic properties of guanylyl cyclase-activating proteins (GCAPs) and recoverin.
Autorzy:
Gorczyca, Wojciech
Kobiałka, Marcin
Kuropatwa, Marianna
Kurowska, Ewa
Powiązania:
https://bibliotekanauki.pl/articles/1043612.pdf
Data publikacji:
2003
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
fluorescence
calcium-binding proteins
recoverin
guanylyl cyclase-activating proteins
Opis:
Guanylyl cyclase-activating proteins (GCAPs) and recoverin are retina-specific Ca2+-binding proteins involved in phototransduction. We provide here evidence that in spite of structural similarities GCAPs and recoverin differently change their overall hydrophobic properties in response to Ca2+. Using native bovine GCAP1, GCAP2 and recoverin we show that: i) the Ca2+-dependent binding of recoverin to Phenyl-Sepharose is distinct from such interactions of GCAPs; ii) fluorescence intensity of 1-anilinonaphthalene-8-sulfonate (ANS) is markedly higher at high [Ca2+]gfree (10 μM) than at low [Ca2+]free (10 nM) in the presence of recoverin, while an opposing effect is observed in the presence of GCAPs; iii) fluorescence resonance energy transfer from tryptophane residues to ANS is more efficient at high [Ca2+]free in recoverin and at low [Ca2+]free in GCAP2. Such different changes of hydrophobicity evoked by Ca2+ appear to be the precondition for possible mechanisms by which GCAPs and recoverin control the activities of their target enzymes.
Źródło:
Acta Biochimica Polonica; 2003, 50, 2; 367-376
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Particulate guanylyl cyclases: multiple mechanisms of activation.
Autorzy:
Kobiałka, Marcin
Gorczyca, Wojciech
Powiązania:
https://bibliotekanauki.pl/articles/1044281.pdf
Data publikacji:
2000
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
signal transduction
calcium-binding proteins
guanylyl cyclases
cyclic nucleotides
Opis:
Cyclic GMP (cGMP), a key messenger in several signal transduction pathways, is synthesized from GTP by a family of enzymes termed guanylyl cyclases, which are found in two forms: cytosolic (soluble) and membrane-bound (particulate). The past decade has brought significant progress in understanding the molecular mechanisms that underlie the regulation of particulate guanylyl cyclases and new members of their family have been identified. It has become more evident that the basic mechanism of catalysis of guanylyl cyclases is analogous to that recognized in adenylyl cyclases. Here we review the known basic mechanisms that contribute to the regulation of particulate guanylyl cyclases.
Źródło:
Acta Biochimica Polonica; 2000, 47, 3; 517-528
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Calcium-binding calmyrin forms stable covalent dimers in vitro, but in vivo is found in monomeric form.
Autorzy:
Sobczak, Adam
Blazejczyk, Magdalena
Piszczek, Grzegorz
Zhao, Gang
Kuznicki, Jacek
Wojda, Urszula
Powiązania:
https://bibliotekanauki.pl/articles/1041431.pdf
Data publikacji:
2005
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
covalent dimer
calmyrin monomer
human lymphocytes
EF-hand calcium-binding proteins
Opis:
The EF-hand Ca^(2+)-binding protein calmyrin is expressed in many tissues and can interact with multiple effector proteins, probably as a sensor transferring Ca^(2+) signals. As oligomerization may represent one of Ca^(2+)-signal transduction mechanisms, we characterised recombinant calmyrin forms using non-reducing SDS/PAGE, analytical ultracentrifugation and gel filtration. We also aimed at identification of biologically active calmyrin forms. Non-reducing SDS/PAGE showed that in vitro apo- and Ca^(2+)-bound calmyrin oligomerizes forming stable intermolecular disulfide bridges. Ultracentrifugation indicated that at a 220 µM initial protein concentration apo-calmyrin existed in an equilibrium of a 21.9 kDa monomer and a 43.8 kDa dimer (trimeric or tetrameric species were not detected). The dimerization constant was calculated as Ka = 1.78 × 103 M^(-1) at 6oC. Gel filtration of apo- and Ca^(2+)-bound calmyrin at a 100 µM protein concentration confirmed an equilibrium of a monomer and a covalent dimer state. Importantly, both monomer and dimer underwent significant conformational changes in response to binding of Ca^(2+). However, when calmyrin forms were analyzed under non-reducing conditions in cell extracts by Western blotting, only monomeric calmyrin was detected in human platelets and lymphocytes, and in rat brain. Moreover, in contrast to recombinant calmyrin, crosslinking did not preserve any dimeric species of calmyrin regardless of Ca^(2+) concentrations. In summary, our data indicate that although calmyrin forms stable covalent dimers in vitro, it most probably functions as a monomer in vivo.
Źródło:
Acta Biochimica Polonica; 2005, 52, 2; 469-476
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The effect of Artichoke (Cynara scolymus L.) on the expression of calcium-binding proteins in the eggshell gland of laying hens
Autorzy:
Abadjieva, D.
Ankova, D.
Grigorova, S.
Kistanova, E.
Powiązania:
https://bibliotekanauki.pl/articles/2087239.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
hens
egg shell gland
genes
artichoke
Źródło:
Polish Journal of Veterinary Sciences; 2021, 24, 1; 127-133
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
p19 detected in the rat retina and pineal gland is a guanylyl cyclase-activating protein (GCAP).
Autorzy:
Dejda, Agnieszka
Matczak, Izabela
Gorczyca, Wojciech
Powiązania:
https://bibliotekanauki.pl/articles/1043693.pdf
Data publikacji:
2002
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
pineal gland
rat
guanylyl cyclase
calcium-binding proteins
guanylyl cyclase-activating proteins
retina
Opis:
The Ca2+-dependent activation of retina-specific guanylyl cyclase (retGC) is mediated by guanylyl cyclase-activating proteins (GCAPs). Here we report for the first time detection of a 19 kDa protein (p19) with GCAP properties in extracts of rat retina and pineal gland. Both extracts stimulate synthesis of cGMP in rod outer segment (ROS) membranes at low (30 nM) but not at high (1 mM) concentrations of Ca2+. At low Ca2+, immunoaffinity purified p19 activates guanylyl cyclase(s) in bovine ROS and rat retinal membranes. Moreover, p19 is recognized by antibodies against bovine GCAP1 and, similarly to other GCAPs, exhibits a Ca2+-dependent electrophoretic mobility shift.
Źródło:
Acta Biochimica Polonica; 2002, 49, 4; 899-905
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Annexins - calcium- and membrane-binding proteins in the plant kingdom Potential role in nodulation and mycorrhization in Medicago truncatula
Autorzy:
Talukdar, Tanuja
Gorecka, Karolina
de Carvalho-Niebel, Fernanda
Downie, J
Cullimore, Julie
Pikula, Slawomir
Powiązania:
https://bibliotekanauki.pl/articles/1040554.pdf
Data publikacji:
2009
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
plant annexins
Nod factors
Medicago truncatula
Opis:
Annexins belong to a family of multi-functional membrane- and Ca2+-binding proteins. The characteristic feature of these proteins is that they can bind membrane phospholipids in a reversible, Ca2+-dependent manner. While animal annexins have been known for a long time and are fairly well characterized, their plant counterparts were discovered only in 1989, in tomato, and have not been thoroughly studied yet. In the present review, we discuss the available information about plant annexins with special emphasis on biochemical and functional properties of some of them. In addition, we propose a link between annexins and symbiosis and Nod factor signal transduction in the legume plant, Medicago truncatula. A specific calcium response, calcium spiking, is an essential component of the Nod factor signal transduction pathway in legume plants. The potential role of annexins in the generation and propagation of this calcium signal is considered in this review. M. truncatula annexin 1 (MtAnn1) is a typical member of the plant annexin family, structurally similar to other members of the family. Expression of the MtAnn1 gene is specifically induced during symbiotic associations with both Sinorhizobium meliloti and the mycorrhizal fungus Glomus intraradices. Furthermore, it has been reported that the MtAnn1 protein is preferentially localized at the nuclear periphery of rhizobial-activated cortical cells, suggesting a possible role of this annexin in the calcium response signal elicited by symbiotic signals from rhizobia and mycorrhizal fungi.
Źródło:
Acta Biochimica Polonica; 2009, 56, 2; 199-210
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-8 z 8

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