- Tytuł:
- Role of rpoS in the regulation of glyoxalase III in Escherichia coli.
- Autorzy:
-
Benov, Ludmil
Sequeira, Fatima
Beema, Anees - Powiązania:
- https://bibliotekanauki.pl/articles/1041571.pdf
- Data publikacji:
- 2004
- Wydawca:
- Polskie Towarzystwo Biochemiczne
- Tematy:
-
methylglyoxal
stationary phase
glyoxalases
RpoS - Opis:
- Methylglyoxal is an endogenous electrophile produced in Escherichia coli by the enzyme methylglyoxal synthase to limit the accumulation of phosphorylated sugars. In enteric bacteria methylglyoxal is detoxified by the glutathione-dependent glyoxalase I/II system, by glyoxalase III, and by aldehyde reductase and alcohol dehydrogenase. Here we demonstrate that glyoxalase III is a stationary-phase enzyme. Its activity reached a maximum at the entry into the stationary phase and remained high for at least 20 h. An rpoS- mutant displayed normal glyoxalase I and II activities but was unable to induce glyoxalase III in stationary phase. It thus appears that glyoxalase III is regulated by rpoS and might be important for survival of non-growing E. coli cultures.
- Źródło:
-
Acta Biochimica Polonica; 2004, 51, 3; 857-860
0001-527X - Pojawia się w:
- Acta Biochimica Polonica
- Dostawca treści:
- Biblioteka Nauki
Artykuł