- Tytuł:
- B-cell chronic lymphocytic leukemia-associated nuclear antigens
- Autorzy:
-
Rogalińska, Małgorzata
Błoński, Jerzy Z
Robak, Tadeusz
Kiliańska, Zofia M - Powiązania:
- https://bibliotekanauki.pl/articles/764933.pdf
- Data publikacji:
- 2008
- Wydawca:
- Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego
- Tematy:
-
B-CLL specific antigens
electrophoresis
immunoblotting - Opis:
- One- and two-dimensional polyacrylamide gel electrophoresis were used to compare the composition of nuclear polypeptides from normal and В-cell chronic lymphocytic leukemia mononuclear cells. Against two electrophoretically-specific nuclear proteins with molecular weight of 38/39 and 44/46 kD a from leukemic cells rabbit sera were obtained. As it was analyzed by Western blot technique the available antisera recognized the 38/39 kDa antigen in 53 of the 56 (94.6%), while the 44/46 kDa in 46 of the 49 (93.9%) of examined В-CLL nuclear fraction preparations, but not in normal ones. The pi values of described leukaemia-specific antigens were determined; p38/39 had pi in the range of pH 6.55 -7.00 and p44/46 - in the range of pH 6.2-6.4.
- Źródło:
-
Acta Universitatis Lodziensis. Folia Biologica et Oecologica; 2008, 4
1730-2366
2083-8484 - Pojawia się w:
- Acta Universitatis Lodziensis. Folia Biologica et Oecologica
- Dostawca treści:
- Biblioteka Nauki
Artykuł