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Wyszukujesz frazę "Anticancer activity" wg kryterium: Temat


Wyświetlanie 1-10 z 10
Tytuł:
Selenium – meaning in the prevention and therapy of cancer diseases
Selen – znaczenie w profilaktyce i terapii schorzeń nowotworowych
Autorzy:
Molenda, Anita
Muszyńska, Bożena
Powiązania:
https://bibliotekanauki.pl/articles/1033700.pdf
Data publikacji:
2017
Wydawca:
Zakład Opieki Zdrowotnej Ośrodek Umea Shinoda-Kuracejo
Tematy:
Selol
anticancer activity
selenium compounds
Opis:
Selenium is a trace element supplied to the human body with food of plant and animal origin. It is a component of many enzymes with antioxidant activity, such as: glutathione peroxidase, seleniumprotein P, thioredoxin reductase and phospholipid hydroperoxide glutathione peroxidase. Being a component of enzymes, it protects cells against deformation and genetic damage thanks to the properties that inhibit the processes of lipid peroxidation, nucleic acids (DNA, RNA). The human body contains about 10-15 mg of selenium, 60% of which is found in erythrocytes, and 40% in blood. The problem of Poland and neighboring countries is the lack of this element in the soil, and therefore in the organisms of herbivorous farm animals. The lack of selenium in the meat of these animals causes significant deficiencies in the human body. In addition, due to the lack of this element in the soil, vegetables and preparations obtained from it do not constitute a suitable dietary source and intensify the problem of deficiency of this element in Europeans. Many studies indicate that both organic and inorganic selenium compounds reduce the progression of cancer by reducing the migration of cancer cells, inhibiting angiogenesis, and consequently reduce metastases.
Źródło:
Medicina Internacia Revuo; 2017, 28, 109; 272-279
0465-5435
Pojawia się w:
Medicina Internacia Revuo
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Biokoniugaty antybiotykow jonoforowych : cele, strategie syntezy i właściwości
Bioconjugates of ionophore antibiotics : goals, synthesis strategies and properties
Autorzy:
Antoszczak, M.
Kordylas, M.
Huczyński, A.
Powiązania:
https://bibliotekanauki.pl/articles/172178.pdf
Data publikacji:
2018
Wydawca:
Polskie Towarzystwo Chemiczne
Tematy:
antybiotyki jonoforowe
jonofory
biokoniugacja
hybrydy
aktywność przeciwbakteryjna
aktywność przeciwnowotworowa
ionophore antibiotics
ionophores
bioconjugation
hybrids
antibacterial
activity
anticancer activity
Opis:
Polyether ionophore antibiotics (ionophores) represent a large group of naturally- occurring lipophilic compounds which are able to form complexes with the metal cations and transport them across the lipid membranes. This process disturbs the intercellular Na+/K+ concentration gradient and intracellular pH, and leads to the mitochondrial damages, cell swelling, vacuolization and finally to apoptosis process. For this reason, ionophores are commonly used in veterinary medicine as the non-hormonal growth-promoting as well as coccidiostatic agents. In this group particularly interesting are monensin and salinomycin (Fig. 1) because of their proved anti-tumour activity, including efficiency against multidrug- -resistant cancer cells and cancer stem cells of different origin. Improved synthetic derivatives of both polyether ionophores are thus of considerable current interest. Selective derivatization of these structures whose display multiple reactive functional groups and, in the case of salinomycin, a sensitive tricyclic spiroketal ring system is however non-trivial. Even so, semi-synthetic analogs reported to date includes i.a. selective derivatization of the carboxyl group, the three hydroxyl groups, the ketone group, the alkene, and epimerization of the characteristic tricyclic salinomycin unit (for more details see: M. Antoszczak, A. Huczyński, B. Brzezinski, Wiad. Chem., 2017, 71, 629). On the other hand, as part of the original program to develop innovatory anti- -cancer pro-drugs and prompted by the idea that cancer cells may be individually effectively killed by monensin and salinomycin, a very interesting direction of research is bioconjugation of these ionophores. In this context, our review article is focused on the possible role of hybrids of both ionophore antibiotics with other biologically active substances (natural amino acids, Cinchona alkaloids, flavonoids, nucleosides) in anti-bacterial and anti-cancer treatment, and gives an overview of their properties.
Źródło:
Wiadomości Chemiczne; 2018, 72, 1-2; 1-28
0043-5104
2300-0295
Pojawia się w:
Wiadomości Chemiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Synteza i aktywność biologiczna pochodnych salinomycyny
Synthesis and biological activity of salinomycin derivatives
Autorzy:
Antoszczak, M.
Huczyński, A.
Brzezinski, B.
Powiązania:
https://bibliotekanauki.pl/articles/171728.pdf
Data publikacji:
2017
Wydawca:
Polskie Towarzystwo Chemiczne
Tematy:
antybiotyki jonoforowe
jonofory
struktura molekularna
aktywność przeciwbakteryjna
aktywność przeciwnowotworowa
ionophore antibiotics
ionophores
molecular structure
antibacterial activity
anticancer activity
Opis:
Polyether ionophore antibiotics (ionophores) represent a large group of naturally- occurring lipid-soluble compounds isolated from actinomycetes strains of Streptomyces genus. Ionophores are able to form complexes with the metal cations, especially sodium and potassium, and transport them across the lipid membranes according to electroneutral or electrogenic transport mechanism. This process disturbs the intercellular Na+/K+ concentration gradient and intracellular pH, leads to the mitochondrial injuries, cell swelling, vacuolization and finally to programmed cell death (apoptosis). For this reason, ionophore antibiotics found commercial use in veterinary medicine as coccidiostatic agents and non-hormonal growth promoters. In addition to the industrial use of ionophores, some of them effectively and selectively inhibit properties of different cancer cells as well as enhance the anti-cancer effects of radio- and/or chemotherapy. In this group, particularly interesting is salinomycin because of its potent anti-microbial and anti-cancer activity, including efficiency against multi-drug resistant cancer cells and cancer stem cells. A very interesting direction of research is the chemical modification of ionophore antibiotics, which can lead to obtaining various derivatives with better biological activity and lower toxicity than those of the starting substances. Because biological activity of ionophore antibiotics and their derivatives is strictly connected with the ability to form characteristic pseudocyclic structures around the complexed cations (host-guest complex), it is also important to establish the detailed information on these structures. In this context, our review article is focused on the possible role of salinomycin and its derivatives in anti-microbial as well as anti-cancer therapy, and gives an overview of the properties of this antibiotic.
Źródło:
Wiadomości Chemiczne; 2017, 71, 7-8; 629-661
0043-5104
2300-0295
Pojawia się w:
Wiadomości Chemiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Naturalne i syntetyczne laktony o aktywności przeciwnowotworowej i przeciwdrobnoustrojowej
Natural and synthetic lactones with anticancer and antimicrobial activity
Autorzy:
Mazur, M.
Powiązania:
https://bibliotekanauki.pl/articles/171876.pdf
Data publikacji:
2011
Wydawca:
Polskie Towarzystwo Chemiczne
Tematy:
laktony aktywne biologicznie
laktony seskwiterpenowe
aktywność przeciwnowotworowa
aktywność przeciwdrobnoustrojowa
biologically active lactones
sesquiterpene lactones
anticancer activity
antimicrobial activity
Opis:
Medicine is one of the most developing branches of knowledge. But even now there are still some diseases which are impossible to cure. Different cancers, antibiotic resistant bacterial infections and fungal pathogenesis infections are still everlasting problems. Thus, two ways of solutions are proposed. First is the return to natural medicines. From the ancient times plants have been used in medicine and the natural products have been an important source of drugs. Nowadays isolation and identification of these compounds, together with the determination of their biological activity, also play an important role. Lactones are the cyclic esters with a wide range of carbon atoms in a lactone ring. They are a very interesting group of compounds which reveal a wide spectrum of biological activity. Terpenoid, especially sesquiterpene lactones and coumarin derivatives, are found in plants of the Asteraceae and Apiaceae families as well as in many others organisms. The naturally occurring lactones often possess anti-inflamatory [1, 2], phytotoxic [3, 4], antiprotozoal [5], and antiviral activities [6]. They are also well known for their anticancer [7, 8] and antimicrobial activities [9, 10]. The second way of obtaining new biologically active lactones is the chemical synthesis of new potent structural analogs of natural bioactive compounds. However, the complexity of natural products and their derivatives may lead to limited supplies, especially when they have the chiral centers which are one of the most important factors influencing their biological activity. It also causes difficulties to determine the mechanism of action. For those reasons, structural simplification plays an important role in the development of analog design. This review is focused on novel literature data about synthetic and natural lactones which reveal anticancer, antibacterial and antifungal activities. Presented compounds show potent biological activity and high selectivity with holding promises for further applications.
Źródło:
Wiadomości Chemiczne; 2011, 65, 1-2; 135-149
0043-5104
2300-0295
Pojawia się w:
Wiadomości Chemiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Zastosowanie chemii "klik" do syntezy biokoniugatów salinomycyny
Application of the click chemistry for the synthesis of salinomycin bioconjugates
Autorzy:
Sulik, Michał
Antoszczak, Michał
Huczyński, Adam
Powiązania:
https://bibliotekanauki.pl/articles/2200436.pdf
Data publikacji:
2022
Wydawca:
Polskie Towarzystwo Chemiczne
Tematy:
salinomycyna
jonofory
biokoniugacja
chemia click
aktywność przeciwnowotworowa
chemia klik
salinomycin
ionophores
bioconjugation
click chemistry
anticancer activity
Opis:
Bioconjugation is a well-known method of designing new drug candidates for many different diseases, including cancer. The idea of the process is to join two or more bioactive molecules by means of a covalent bond. Thus, obtained hybrids often exhibit higher efficiency compared to that of the starting compounds. Recently, the use of click chemistry, especially Huisgen 1,3-dipolar cycloaddition, has attracted much attention for the synthesis of bioconjugates of natural compounds. The great advantage of this reaction is its high yield and enzymatic stability of the 1,2,3-triazole ring. Mild conditions of this reaction guarantee that it can be used to modify compounds with low stability, such as salinomycin – a representative of ionophore antibiotics. Salinomycin is a naturally occurring lipophilic compound isolated from Streptomyces albus. It is capable of forming complexes with metal cations and transport them across the lipid membranes. This process disturbs the intercellular Na+ /K+ concentration gradient and leads to apoptosis (programmed cell death). Salinomycin exhibits high anticancer activity, including efficiency against multidrug-resistant cancer cells and cancer stem cells of different origin. Chemical modification of the salinomycin skeleton to increase its biological activity is a very interesting research direction. Our review article is focused on the application of click chemistry for the synthesis of salinomycin bioconjugates with many different biologically active compounds (Cinchona alkaloids, nucleosides, triphenylphosphonium cation, betulinic acid and other ionophore antibiotics). Some of the obtained hybrids exhibit higher efficiency compared to that of the starting compounds, e.g., increased anticancer activity, the ability to overcome multi-drug resistance, or improved ionophoretic properties. These results are a good starting point for further research on the use of click chemistry in the synthesis of highly functional hybrids of natural compounds.
Źródło:
Wiadomości Chemiczne; 2022, 76, 11-12; 883--907
0043-5104
2300-0295
Pojawia się w:
Wiadomości Chemiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Pochodne 1,2,3-triazolu. Potencjalne leki?
Derivatives of 1,2,3-triazole. Potential drugs?
Autorzy:
Bankowska, E.
Wróblewski, A. E.
Powiązania:
https://bibliotekanauki.pl/articles/171634.pdf
Data publikacji:
2012
Wydawca:
Polskie Towarzystwo Chemiczne
Tematy:
pochodne 1,2,3-triazolu
aktywność przeciwbakteryjna
aktywność przeciwgrzybicza
aktywność przeciwgruźlicza
aktywność przeciwpsychotyczna
aktywność przeciwdrgawkowa
aktywność przeciwzapalna
aktywność hipoglikemiczna
aktywność przeciwnowotworowa
aktywność przeciwwirusowa
1,2,3-triazole derivatives
antibacterial activity
antifungal activity
antitubercular activity
antipsychotic activity
anticonvulsant activity
anti-inflammatory activity
hypoglycemic activity
anticancer activity
antiviral activity
Opis:
Recently, 1,2,3-triazoles have gained an increased attention in the field of drug discovery because several derivatives have already been marketed as medications (e.g. tazobactam, cefatrizine, rufinamide) [1, 2] and many of them appeared to be very active in diverse biological studies including plinambulin 69 currently in the last stage of the clinical trials [60]. In this review very recent investigations of antibacterial, antitubercular, antifungal, antipsychotic, antiepileptic, anti-inflammatory, hypoglycemic, anticancer and antiviral properties of 1,2,3-triazole derivatives are discussed. These studies allowed to select several compounds which were found to be more active in comparison to the already used drugs.
Źródło:
Wiadomości Chemiczne; 2012, 66, 11-12; 993-1022
0043-5104
2300-0295
Pojawia się w:
Wiadomości Chemiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Izoksazolidynowe analogi nukleozydów
Isoxazolidine analogues of nucleosides
Autorzy:
Kokosza, K.
Piotrowska, D. G.
Powiązania:
https://bibliotekanauki.pl/articles/171674.pdf
Data publikacji:
2012
Wydawca:
Polskie Towarzystwo Chemiczne
Tematy:
1,3-dipolarna cykloaddycja
nitrony
izoksazolidyny
analogi nukleozydów
nukleozasady
C-nukleozydy
homonukleozydy
nukleozydy
fosfonylowane nukleozydy
psiko-nukleozydy
aktywność przeciwwirusowa
aktywność przeciwnowotworowa
1,3-dipolar cycloaddition
nitrones
isoxazolidines
nucleoside analogues
nucleobases
C-nucleosides
homonucleosides
nucleosides
phosphonylated nucleosides
psico-nucleosides
antiviral activity
anticancer activity
Opis:
Compounds having isoxazolidine moiety are of special interest since they show a broad spectrum of biological activity, including anticancer [1–5], antiviral [6], antibacterial [7–9] and antifungal activities [9–12]. Extensive studies on isoxazolidine moiety containing compounds resulted in discovery of several potentially antiviral and anticancer drugs (e.g. pyridemine-A 1 [2, 3], as well as isoxazolidines substituted with thymine and 5-fluorouracil 52a (AdT) [38–40] and 59 [(–)-AdFU] [41–43], respectively). In this review the most spectacular examples of the synthesis of isoxazolidine analogues of nucleosides are discussed and their biological activity is emphasized.
Źródło:
Wiadomości Chemiczne; 2012, 66, 11-12; 1041-1070
0043-5104
2300-0295
Pojawia się w:
Wiadomości Chemiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Ocena możliwości zwiększenia zawartości sprzężonych dienów kwasu linolowego (CLA) w mięsie i przetworach mięsnych
Evaluation of the possibilities to increase the content of conjugated linoleic acid (CLA) in meat and meat product
Autorzy:
Piotrowska, A.
Swiader, K.
Waszkiewicz-Robak, B.
Swiderski, F.
Powiązania:
https://bibliotekanauki.pl/articles/877603.pdf
Data publikacji:
2012
Wydawca:
Narodowy Instytut Zdrowia Publicznego. Państwowy Zakład Higieny
Tematy:
sprzezone dieny kwasu linolowego
mieso wieprzowe
przetwory miesne
wlasciwosci prozdrowotne
dzialanie przeciwnowotworowe
dzialanie przeciwmiazdzycowe
dzialanie przeciwzapalne
choroby czlowieka
choroby cywilizacyjne
trzoda chlewna
zywienie zwierzat
preparat CLA
conjugated linoleic acid
pork
meat product
healthy property
anticancer activity
antiinflammatory property
human disease
civilization disease
pig
animal feeding
Opis:
Scharakteryzowano właściwości prozdrowotne sprzężonych dienów kwasu linolowego (CLA) oraz dokonano oceny możliwości zwiększenia ich zawartości w mięsie wieprzowym i jego przetworach. Badania z udziałem zwierząt laboratoryjnych wskazują na przeciwnowotworowe, przeciwmiażdżycowe i przeciwzapalne działanie CLA, sugerują także wpływ na redukcję tkanki tłuszczowej oraz zwiększenie przyrostu masy mięśniowej. Jednak liczba obserwacji u ludzi jest niewystarczająca aby móc w pełni ocenić związek pomiędzy spożyciem CLA a zmniejszaniem ryzyka chorób cywilizacyjnych, dlatego konieczne jest prowadzenie dalszych badań. Dane literaturowe wskazują, że zastosowanie w żywieniu trzody chlewnej dodatku preparatów CLA, pozwala zwiększyć udział tej grupy związków w uzyskanym surowcu, przy czym istotnie wyższą akumulację stwierdza się dla izomeru cis-9, trans-11. Zmianom tym towarzyszy jednak niekorzystne z punktu widzenia zdrowia człowieka zwiększenie udziału kwasów nasyconych kosztem kwasów jednonienasyconych. W produkcji przetworów mięsnych lepszym sposobem zwiększenia udziału sprzężonych dienów kwasu linolowego wydaje się być stosowanie dodatku preparatu CLA na etapie procesu produkcji, ponieważ nie wpływa ono na poziom kwasów nasyconych. Mięso wieprzowe wzbogacone w CLA i uzyskane z niego przetwory charakteryzują się małą podatnością na procesy utleniania, co może wynikać ze sprzężenia wiązań podwójnych, właściwości antyoksydacyjnych sprzężonych dienów kwasu linolowego, a także ze zwiększonego udziału nasyconych kwasów tłuszczowych. Zagadnienie korzystnego wpływu na zdrowie człowieka mięsa wieprzowego i jego przetworów o podwyższonym udziale CLA wymaga dalszych badań prowadzonych na ludziach. Dopiero wówczas tego typu wyroby można będzie zaliczyć do grupy żywności funkcjonalnej.
The paper characterizes pro-health properties of conjugated linoleic acid (CLA) and assesses the possibility of increasing their content in pork and pork meat products. Studies conducted on animals indicate antitumor, antiatherosclerotic and antiinflammatory effect of CLA, also find impact on reducing body fat and increasing muscle growth. However, the number of observations concerning human populations is insufficient to fully evaluate the relationship between CLA intake and reducing the risk of lifestyle diseases. Therefore, it is necessary to conduct further research. Literature data indicate that the use in pigs feed suplementation with CLA preparations, can increase the content of these compounds in the meat and also show, that isomer cis-9, trans-11 is accumulated at significantly higher level. However, these changes were accompanied by increased the share of saturated fatty acids at the expense of monounsaturated which is unfavorable for human health. A better way to increase the CLA content in pork meat appears to be the addition of CLA preparation during the production process, because it does not affect the level of saturated fats. Pork and pork meat products enriched in CLA are characterized by low susceptibility to oxidation, which may result from the coupling of double bonds, antioxidantive properties of conjugated linoleic acid and the increased content of saturated fatty acids. The issue of beneficial effects on human health of pork and pork products with a higher content of CLA, requires further studies conducted on humans. Only then these products can be classified as a functional foods.
Źródło:
Roczniki Państwowego Zakładu Higieny; 2012, 63, 3
0035-7715
Pojawia się w:
Roczniki Państwowego Zakładu Higieny
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Farmakologiczna aktywność flawonoidów i aminoflawonów
Pharmacological activities of aminoflavones
Autorzy:
Szeliga, D.
Korabik, M.
Ochocki, J.
Powiązania:
https://bibliotekanauki.pl/articles/172060.pdf
Data publikacji:
2018
Wydawca:
Polskie Towarzystwo Chemiczne
Tematy:
flawonoidy
flawony
aminoflawony
aktywność biologiczna
właściwości przeciwnowotworowe
flavonoids
flavones
aminoflavones
biological activity
anticancer properties
Opis:
Aminoflavones belong to a group of flavonoids, compounds commonly found in nature. Their pharmacological and biochemical effects include cytotoxic, antioxidant and antitumor properties. The studies have shown that complexes of aminoflavons with metal ions can be potential drugs and seem to be promising in the treatment of ovarian cancer, breast cancer, lung adenocarcinoma and melanoma. In addition aminoflavones have a lower cytotoxic activity towards healthy cells than another compounds. In the view of their wide pharmacological and biological actions, they seem to have great therapeutic potential.
Źródło:
Wiadomości Chemiczne; 2018, 72, 7-8; 563-583
0043-5104
2300-0295
Pojawia się w:
Wiadomości Chemiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Aminokwasy, glikany, peptydy i białka w ścieżkach diagnostycznych i terapeutycznych chorób cywilizacyjnych XXI wieku : projektowanie i charakterystyka fizykochemiczna oraz strukturalna
Amino acids, glycans, peptides and proteins in the diagnostic and therapeutic pathways of the 21st century civilization diseases : design, physicochemical and structural characterisation
Autorzy:
Bylińska, Irena
Dzierżyńska, Maria
Giżyńska, Małgorzata
Guzow, Katarzyna
Jankowska, Elżbieta
Jurczak, Przemysław
Kaczyński, Zbigniew
Karska, Natalia
Kowalczyk, Agnieszka
Kuncewicz, Katarzyna
Orlikowska, Marta
Sawicka, Justyna
Spodzieja, Marta
Szpakowska, Nikola
Szymańska, Aneta
Wieczerzak, Ewa
Witkowska, Julia
Rodziewicz-Motowidło, Sylwia
Powiązania:
https://bibliotekanauki.pl/articles/2200549.pdf
Data publikacji:
2022
Wydawca:
Polskie Towarzystwo Chemiczne
Tematy:
fluorophores
fluorescence spectroscopy
antimicrobial activity
anticancer activity
Cystapep
Stahylococcus aureus
antimicrobial compounds
amyloidogenic protein
mutagenesis
fibrilization
proteasome
aging
neurodegeneration
self-assembling peptides
tissue engineering
biomaterials
immune checkpoints
peptide inhibitors
immunotherapy
ligands of TAP protein
viral diseases
NMR structure of the UL49.5 protein
glycans
glycoconjugates
fluorofory
spektroskopia fluorescencyjna
aktywność przeciwdrobnoustrojowa
aktywność antynowotworowa
Staphylococcus aureus
związki przeciwbakteryjne
białko amyloidogenne
mutageneza
fibrylizacja
proteasom
procesy starzeniowe
neurodegeneracja
peptydy samoorganizujące
inżynieria tkankowa
biomateriały
punkty kontrolne układu immunologicznego
inhibitory peptydowe
immunoterapia
ligandy białka TAP
choroby wirusowe,
struktura NMR białka UL49.5
glikany
glikokoniugaty
Opis:
The civilization diseases of the 21st century are non-infectious disorders, affecting a large part of modern society. They are associated with the significant development of industry and technology, and hence with environmental pollution and an unhealthy lifestyle. These factors have led to the development of many civilization diseases, which currently include: cardiovascular diseases, respiratory diseases, diabetes, obesity, malignant tumors, gastrointestinal diseases, mental disorders and allergic diseases. The development of technologies, including modern therapies and new drugs, resulted in increase in life expectancy. This creates a global problem of an aging population with an increasing number of diseases of the old age, i.e. dementias. In addition, sedentary lifestyles and changing diets are the reasons why more and more people develop metabolic diseases, as well as neurological and cognitive disorders characterized by progressive damage to nerve cells and dementia. Currently, problem on a global scale is also the growing resistance to existing antimicrobial drugs. Therefore, the scientists face many challenges related to searching for the causes of these diseases, their diagnosis and treatment. Scientific research conducted at the Department of Biomedical Chemistry at the Faculty of Chemistry of the University of Gdańsk is part of this research trend. In this publication, we discuss various research topics with the long-term aim of solving the problems associated with the diseases mentioned above. The following chapters are dedicated to (i) looking for new effective fluorophores with diagnostic and anti-cancer activity; (ii) designing of new compounds with antibacterial and antiviral activity and their synthesis; (iii) investigating the mechanisms of amyloid deposit formation by human cystatin C and possibilities of inhibition of this process; (iv) designing and studies of compounds activating the proteasome with the potential to suppress the development of neurodegenerative diseases; (v) designing peptide fibrils and hydrogels as drug carriers; (vi) searching for peptide inhibitors of immune checkpoint as potential drugs for immunotherapy; (vii) studying the mechanism of action of selected herpesviruses by determining the structure of viral proteins and (viii) studying the composition of natural glycans and glycoconjugates in order to better understand the mechanisms of interaction of bacteria with the environment or with the host.
Źródło:
Wiadomości Chemiczne; 2022, 76, 5-6; 393--431
0043-5104
2300-0295
Pojawia się w:
Wiadomości Chemiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-10 z 10

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