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    Wyświetlanie 1-8 z 8
    Tytuł:
    Safety and efficacy of granulocyte colony stimulating factor in a patient with tetraplegia caused by cervical hyperextension injury: a case report
    Autorzy:
    Okurowska-Zawada, B
    Kułak, W
    Sienkiewicz, D
    Paszko-Patej, G
    Dmitruk, E
    Kalinowska, A
    Wojtkowski, J
    Korzeniecka–Kozerska, A
    Powiązania:
    https://bibliotekanauki.pl/articles/1916580.pdf
    Data publikacji:
    2014
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    Cervical hyperextesniosn
    spinal cord injury
    tetraplegia
    male
    Opis:
    he authors present the case of a 17-year-old boy who suffered a cervical spinal injury as a result of the sharp bending of the head after slipping (without falling). After about 30 minutes, he began to feel tingling in the limbs and he developed tetraparesis. He went through physical rehabili-tation, psychological rehabilitation, occupational therapy, and periodic catheterization. Additionally, we introduced to him a low dose of analog granulocyte colony-stimulating factor (G-CSF). G-CSF 5 μg/kg was given subcutaneously daily for 5 days per month for 3 months, again after 6 months, and again after 10 months. The boy could sit indecently and walk with assistance. A significant increase in muscle strength in this patient with tetraplegia after 10 months of treatment may indicate beneficial effects of G-CSF in this disorder.
    Źródło:
    Progress in Health Sciences; 2014, 4, 2; 181-184
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Gastrodin ameliorates spinal cord injury via antioxidant and anti-inflammatory effects
    Autorzy:
    Du, Fangtao
    Wang, Xiaoning
    Shang, Bo
    Fang, Jifeng
    Xi, Yuting
    Li, Aijuan
    Diao, Yenze
    Powiązania:
    https://bibliotekanauki.pl/articles/1038788.pdf
    Data publikacji:
    2016
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    spinal cord injury
    gastrodin
    inflammation
    oxidative stress
    Nrf2
    Opis:
    Spinal cord injury (SCI) is one of the most severe traumatic injuries that results in dysfunction of limbs and trunk below the damaged section. Recent studies have shown that gastrodin (GAS) could improve the recovery of SCI. In the current study, we aimed to examine the possible mechanism underlying the effect of GAS on recovery of SCI in rats. In rats with SCI, GAS improved locomotor functions and decreased permeability of blood-spinal cord barrier, as illustrated by increase of Basso-Beattie-Bresnahan scores and decrease of Evans blue leakage. In addition, GAS inhibited inflammation, as evidenced by decrease of proinflammatory cytokines, including tumor necrosis factor α (TNFα) and interleukin-1β (IL-1β) in rats following SCI. Moreover, increase of TBARS content and decrease of glutathione (GSH) content and superoxide dismutase (SOD) activities in SCI rats were inhibited by GAS. Furthermore, GAS enhanced mRNA expression of nuclear factor (erythroid-derived 2)-like 2 (Nrf2), catalytic subunit of γ-glutamylcysteine ligase (GCLc) and modified subunit of γ-glutamylcysteine ligase (GCLm). The data suggested that GAS may promote the recovery of SCI through the enhancement of Nrf2-GCLc/GCLm signaling pathway, and subsequent improvement of oxidative stress and inflammation, resulting in decrease of permeability of BSCB and improved recovery of locomotor function in rats with SCI. The results have provided novel insights into GAS-related therapy of SCI and associated neurodegenerative diseases.
    Źródło:
    Acta Biochimica Polonica; 2016, 63, 3; 589-593
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Contemporary methods of urinary system evaluation in patients after spinal injury complicated by neurological deficits: Diagnostics of the upper urinary tract
    Współczesne metody oceny układu wydalniczego u osób po urazie kręgosłupa powikłanym zaburzeniami neurologicznymi – diagnostyka górnych dróg moczowych
    Autorzy:
    Tederko, Piotr
    Lewandowski, Jacek
    Krasuski, Marek
    Kiwerski, Jerzy
    Powiązania:
    https://bibliotekanauki.pl/articles/1938566.pdf
    Data publikacji:
    2007
    Wydawca:
    Akademia Wychowania Fizycznego im. Bronisława Czecha w Krakowie
    Tematy:
    spinal injury
    Neurological deficits
    urinary system
    Urinary Tract
    uraz kregosłupa
    zaburzenia neurologiczne
    układ wydalniczy
    drogi moczowe
    Opis:
    Introduction: Morbidity and mortality related to urinary tract diseases in patients after spinal injury with neurological disturbances (SIND) are modifiable if prompt and rational diagnostics and therapy are implemented in comprehensive care. SIND increases the risk of urinary tract damage resulting from neurogenic bladder dysfunction, sequels of patient’s immobilisation, nephrotoxic effect of pharmacotherapy, necessity of bladder catheterisation. Severe damage to the urinary system resulting from reflux, urolithiasis, hydronephrosis, recurrent pyelonephritis can occur both during the early and the late phase following SIND. The risk of urinary tract cancer is markedly increased in SIND patients. The natural history of urinary tract diseases in SIND patients might be changed. The course of the disease can be scant in symptoms and signs until late stages. Study design: Overview of scholarly literature.Aim of the study: Presentation and analysis of clinical usefulness of modern tests applied in diagnostics of the urinary tract function in SIND patients. We discussed appropriateness and clinical usefulness of imaging and functional procedures of the upper urinary tract evaluation with special emphasis on basic laboratory tests, modern methods of glomerular filtration rate (GFR) assessment in SIND patients, as well as on the traditional and modern imaging studies.Conclusions: Modern comprehensive care of a patient with SIND, both at the early and late stage following spinal injury, should comprise systematic monitoring of renal function. Efficacious diagnosis is based on meticulous clinical examination. Auxiliary tests are performed according to their availability and the anticipated clinical relevance. First line diagnostic tests should comprise non-invasive techniques. Systematic and credible GFR assessment is indicated in SIND patients. Tests of choice include: 51CrEDTA or 99mTcDTPA clearance, assessment of cystatin-C level, as well as routine imaging studies of the kidneys such as renal radioisotope scanning and ultrasound examination. Urography and computed tomography may serve as auxiliary imaging techniques.
    Źródło:
    Medical Rehabilitation; 2007, 11(3); 21-28
    1427-9622
    1896-3250
    Pojawia się w:
    Medical Rehabilitation
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Impact of spinal injury with neurological consequences on sexual function: Sexual dysfunctions in men
    Wpływ urazu kręgosłupa powikłanego zaburzeniami neurologicznymi na funkcje seksualne – dysfunkcje seksualne u mężczyzn
    Autorzy:
    Tederko, Piotr
    Krasuski, Marek
    Kiwerski, Jerzy
    Powiązania:
    https://bibliotekanauki.pl/articles/1938607.pdf
    Data publikacji:
    2007
    Wydawca:
    Akademia Wychowania Fizycznego im. Bronisława Czecha w Krakowie
    Tematy:
    spinal injury with neurological consequences
    Men
    sexual dysfunction
    Infertility
    Rehabilitation
    uraz kregosłupa powikłany zaburzeniami neurologicznymi
    dysfunkcje seksualne
    niepłodnosc
    rehabilitacja
    mężczyźni
    Opis:
    Sexual impairment and decreased fertility constitute a part of a complex dysfunction typical for men with spinal injury with neurological consequences (SINC). Despite the progress in medical sciences and quality of care provided for disabled persons, the problem is often neglected by medical professionals and caregivers.Aim of the study: Presentation of patophysiological background and specificity of sexual dysfunction typical for men following SINC. Review of contemporary treatment modalities designed for erectile dysfunction and infertility in men after SINC.Method: Literature review, authors’ clinical experience.Results and conclusions: Specific neurological deficit with overlapping adaptation problems and depression account for erectile dysfunction in men after SINC. There is a wide range of efficient therapies addressed to patients suffering from erectile disturbances resulting from SINC. Selection of a proper therapy depends on location (level) of the lesion of a neural structure, type of deficit, functional status, presence of symptoms of autonomic dysreflexia, concomitant diseases and patient’s individual preferences. Patient’s awareness of the disability and positive attitude towards acceptance of alternative forms of sexual expressions are crucial for the therapeutic success. Ejaculation dysfunction and infertility are common among men after SINC. Application of contemporary methods of assisted reproduction may be efficient in about half of male population with SINC.
    Źródło:
    Medical Rehabilitation; 2007, 11(4); 27-31
    1427-9622
    1896-3250
    Pojawia się w:
    Medical Rehabilitation
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Impact of spinal injury with neurological consequences on sexual function: Sexual dysfunctions in women
    Autorzy:
    Tederko, Piotr
    Krasuski, Marek
    Kiwerski, Jerzy
    Powiązania:
    https://bibliotekanauki.pl/articles/1938610.pdf
    Data publikacji:
    2007
    Wydawca:
    Akademia Wychowania Fizycznego im. Bronisława Czecha w Krakowie
    Tematy:
    spinal injury with neurological consequences
    Women
    sexual dysfunction
    partner relationships
    Rehabilitation
    uraz kregosłupa powikłany zaburzeniami neurologicznymi
    me/czyzni
    dysfunkcje seksualne
    niepłodnosc
    rehabilitacja
    Opis:
    Patophysiological background of sexual dysfunctions in women after spine injury with neurological consequePatophysiological background of sexual dysfunctions in women after spine injury with neurological consequences (SINC) is a difficult object of scientific investigations and is not as accurately described as sexual impairment in men after SINC. In particular, systematic reports on pregnancy and its complications in women after SINC are lacking. Aim of the study: Presentation of backgrounds and specificity of sexual disorders, dysfunctions of partner relationships and contraception in women after SINC.Method: Literature review, authors’ clinical experience.Results and conclusions: Persons with sexual dysfunction following SINC should be subjected to psychological evaluation and specified sexual education. These specific interventions should be introduced at the appropriate time and take into account functional progress made during rehabilitation and the level of patients’ acceptance of disability. Partner’s involvement is crucial for effective psychotherapy of persons after SINC. A possibility to take the advantage of experience of other persons with a similar disorder is of particular value during the therapy. There is a positve correlation between the ability to experience sexual satisfaction and quality of social adaptation after SINC. The form, acceptance and efficiency of sexual education in persons after SINC are affected by cultural conditions.nces (SINC) is a difficult object of scientific investigations and is not as accurately described as sexual impairment in men after SINC. In particular, systematic reports on pregnancy and its complications in women after SINC are lacking. Aim of the study: Presentation of backgrounds and specificity of sexual disorders, dysfunctions of partner relationships and contraception in women after SINC.Method: Literature review, authors’ clinical experience.Results and conclusions: Persons with sexual dysfunction following SINC should be subjected to psychological evaluation and specified sexual education. These specific interventions should be introduced at the appropriate time and take into account functional progress made during rehabilitation and the level of patients’ acceptance of disability. Partner’s involvement is crucial for effective psychotherapy of persons after SINC. A possibility to take the advantage of experience of other persons with a similar disorder is of particular value during the therapy. There is a positve correlation between the ability to experience sexual satisfaction and quality of social adaptation after SINC. The form, acceptance and efficiency of sexual education in persons after SINC are affected by cultural conditions.
    Źródło:
    Medical Rehabilitation; 2007, 11(4); 32-35
    1427-9622
    1896-3250
    Pojawia się w:
    Medical Rehabilitation
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Risk analysis for operating active wheelchairs in non-urban settings
    Autorzy:
    Sydor, Maciej
    Krauss, Andrzej
    Krauss, Hanna
    Powiązania:
    https://bibliotekanauki.pl/articles/990867.pdf
    Data publikacji:
    2017
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    independent living
    preliminary hazard analysis (pha)
    risk analisis
    wheelchair
    safety measures
    spinal cord injury (sci)
    Opis:
    Introduction. A wheelchair is a special vehicle designed specifically for people with walking limitations. One of the types is an active wheelchair. This is a manually propelled wheelchair, the design and structure of which maximise the mobility of its given user at the expense of accepted instability. Objective. The aim of this study was to identify and present a hierarchy of potential incidents causing a health hazard and reducing the mobility of individuals with ambulatory disability who use active wheelchairs in non-urban settings. Materials and methods. Information about incidents connected with wheelchair use was collected from interviews with disabled individuals, based on a questionnaire. Recorded data were analysed using the Preliminary Hazard Analysis (PHA). Results. The results comprise a list of hazards for wheelchair user with ascribed priority numbers metrising their significance. Conclusions. An ordered list of hazards connected with wheelchair operation situations is useful when designing active wheelchairs and when learning the technique of wheelchair riding.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2017, 24, 3
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Changes of ventilatory parameters in the positional training of persons after cervical spinal cord injury
    Zmiany parametrów wentylacyjnych w trakcie pionizacji osób po urazie rdzenia kręgowego w odcinku szyjnym
    Autorzy:
    Tederko, Piotr
    Krasuski, Marek
    Powiązania:
    https://bibliotekanauki.pl/articles/1942910.pdf
    Data publikacji:
    2009
    Wydawca:
    Akademia Wychowania Fizycznego im. Bronisława Czecha w Krakowie
    Tematy:
    spinal cord injury
    Spirometry
    ventilatory parameters
    Rehabilitation
    postural training
    uszkodzenie rdzenia kregowego
    spirometria
    parametry wentylacyjne
    rehabilitacja
    trening posturalny
    Opis:
    Background: Cervical spinal cord injury (CSCI) is followed by mixed respiratory dysfunction.Purpose: Evaluation of the ventilatory parameters of CSCI patients in postures typical for positional training. Material: 51 CSCI patients in a mean age of 34.4 (SD=14.6) years; complete motor deficite (CMD) 66.6%; injury of C5 level or above – 68.6%. Control group(CG): 10 healthy volunteers. Method: Spirometry and flow-volume examination in recumbent (R), sitting (S) and vetrical 60o tilt (V) positions. Main results: Expiratory reserve volume (ERV) undergoes significant positional changes in CG (R: 1.34 L, H: 0.25 L, V: 0.79 L; p=0.02), but not in CSCI patients. Transition from R to S in CMD persons results in a significant decrease in vital capacity (VC) (from 2.45 to 1.75 L; p=0.0008); inspiratory capacity (IC) (from 2.48 to 1.41 L; p=0.0008); forced expiratory volume in 1 second (FEV1) (from 2.21 to 1.64 L; p=0.002); forced vital capacity (FVC) (from 2.55 to 1.78 L; p=0.0004). The FEV1/FVC rate does not depend on positional changes ranging from 89.7% to 93.9% of the reference values. Ventilatory parameters in the incomplete motor deficite (ICMD) group do not differ significantly between the examined body positions. Transition between R and S in the CMD group results in a significant decrease in the peak expiratory flow (PEF) (from 4.23 to 3.53 L/s) and the peak inspiratory flow (PIF) (from 3.89 to 3.43 L/s), while in ICMD the PEF increases from 4.01 to 4.39 L/s and the PIF increases from 3.66 to 4.18 L/s.Conclusions: Transition from R to S in CSCI patients results in increased restriction. CMD patients express a reduction of peak flows while in the ICMD peak flows increase after transition between R and S. Shifting from S to a 60o vertical tilt with standard trunk stabilization does not change significantly the ventilatory parameters in CSCI patients.
    Źródło:
    Medical Rehabilitation; 2009, 13(1); 11-17
    1427-9622
    1896-3250
    Pojawia się w:
    Medical Rehabilitation
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Sudden quadriparesis in a teenager: a case study and literature review
    Niedowład czterokończynowy o nagłym początku u nastolatka: opis przypadku i przegląd piśmiennictwa
    Autorzy:
    Lipiec, Agata
    Barszcz, Sławomir
    Bekiesińska-Figatowska, Monika
    Goszczańska-Ciuchta, Alicja
    Szczepanik, Elżbieta
    Powiązania:
    https://bibliotekanauki.pl/articles/2057225.pdf
    Data publikacji:
    2017
    Wydawca:
    Polskie Towarzystwo Neurologów Dziecięcych
    Tematy:
    quadriparesis
    cervical spinal stenosis (CSS)
    cervical cord neurapraxia (CCN)
    spinal cord injury (SCI)
    magnetic resonance imaging (MRI)
    niedowład czterokończynowy
    zwężenie odcinka szyjnego kanału kręgowego
    neurapraksja odcinka szyjnego rdzenia kręgowego
    uraz rdzenia kręgowego
    rezonans magnetyczny
    Opis:
    Introduction: Syndrome of neurapraxia of the cervical spinal cord with transient quadriplegia was first described by Torg et al. in 1986. Cervical cord neurapraxia is defined as a transient neurological deficits following cervical cord trauma. Aim: In this paper we wanted to share our experience with a rare case of a sudden quadriparesis in paediatric population. Material and methods: The presented case involved a 17-year-old male intensively practicing strength and combat sports who suddenly suffered from quadriparesis with sensory disturbances. Symptoms developed 60 hours after a hyperextension head injury had taken place and subsided completely after 72 hours. Spinal magnetic resonance imaging demonstrated insidious disc changes with congenital cervical spinal stenosis without myelopathy. Disc changes within levels L4/L5 and L5/S1 with central disc protrusion L5/S1 with no central and foraminal stenosis were observed. Differential diagnosis of the case is also presented. Results: Taking into consideration the patient’s intense boxing and sparring practice with exposure to head and neck injuries and cervical spinal stenosis, sports-related cervical neurapraxia with transient quadriparesis was diagnosed. Conclusions: Cervical cord neurapraxia is a common consequence of sports-related injury, which should be considered in differential diagnosis, especially in athletes.
    Wprowadzenie. Neurapraksja odcinka szyjnego rdzenia kręgowego z przemijającym porażeniem czterokończynowym została po raz pierwszy opisana przez Torga i in. w 1986 r. Zespół ten jest definiowany jako przemijające deficyty neurologiczne po przebytym urazie rdzenia. Cel: Podzielenie się doświadczeniami dotyczącymi przypadku niedowładu czterokończynowego o nagłym początku, rzadko obserwowanego w populacji dziecięcej. Materiał i metody: Przedstawiono przypadek 17-letniego chłopca intensywnie uprawiającego sporty siłowe i walki, u którego nagle wystąpił niedowład czterokończynowy z zaburzeniami czucia. Objawy rozwinęły się około 60 godzin po urazie przeprostnym głowy i ustąpiły całkowicie po około 72 godzinach. Badaniem MR odcinka szyjnego kręgosłupa stwierdzono wąski wrodzony kanał kręgowy z rozpoczynającą się dyskopatią, bez cech mielopatii. Uwidoczniono dyskopatię L4/L5 i L5/S1 z centralną przepukliną dyskową L5/S1, bez istotnej stenozy centralnej i otworowej. Przedstawiono także diagnostykę różnicową przypadku. Wyniki: U pacjenta wzięliśmy pod uwagę intensywne uprawianie boksu i udział w sparingach oraz związaną z tym ekspozycję na urazy głowy i szyi. Kierując się kryteriami diagnostycznymi: związkiem czasowym z urazem oraz wąskim kanałem kręgowym w odcinku szyjnym, u pacjenta rozpoznaliśmy neurapraksję odcinka szyjnego rdzenia kręgowego jako przyczynę przejściowego niedowładu czterokończynowego. Wnioski: Neurapraksja odcinka szyjnego rdzenia kręgowego jest z reguły następstwem urazu związanym z uprawianiem sportów i powinna być brana pod uwagę w diagnostyce różnicowej, zwłaszcza u sportowców. Słowa kluczowe: niedowład czterokończynowy, zwężenie
    Źródło:
    Neurologia Dziecięca; 2017, 26, 53; 63-66
    1230-3690
    2451-1897
    Pojawia się w:
    Neurologia Dziecięca
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-8 z 8

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