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    Wyświetlanie 1-3 z 3
    Tytuł:
    Comparison of the cardiovascular and respiratory effects and sevoflurane requirement in dogs premedicated with two doses of medetomidine and butorphanol undergoing surgical sterilization
    Autorzy:
    D. Juodzente
    Macas, A.
    Karveliene, B.
    Petkevicius, S.
    Riskeviciene, V.
    Powiązania:
    https://bibliotekanauki.pl/articles/2087757.pdf
    Data publikacji:
    2018
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    Medetomidine
    butorphanol
    sevoflurane
    sedation
    canine
    Źródło:
    Polish Journal of Veterinary Sciences; 2018, 21, 1; 101-110
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    NEUROPHARMACOLOGICAL EVALUATION OF SEDATIVE AND MUSCLE RELAXANT PROPERTIES OF RAPHANUS CAUDATUS IN ALBINO MICE
    Autorzy:
    younus, ishrat
    siddiq, afshan
    sadaf, rafia
    Powiązania:
    https://bibliotekanauki.pl/articles/895399.pdf
    Data publikacji:
    2019-10-30
    Wydawca:
    Polskie Towarzystwo Farmaceutyczne
    Tematy:
    muscle relaxation
    sedation
    Raphanus caudatus
    ethanol extract
    Opis:
    Objectives In present days vegetables and fruits provided by nature are underutilized and underestimated. Raphanus caudatus, is one of an ignored vegetable belonging to radish plant because it is not only underutilized by the population but also the researches had not focused to identify its phytochemistry as well as pharmacological potential. The present study was designed with the aim to evaluate bioactive principles along with sedative and muscle relaxant properties of ethanol extract of Raphanus caudatus in mouse model. Methodology In the current study effects of ethanol extract of Raphanus caudatus were observed on general performance and behavioral changes of mice. Moreover sedative and muscle relaxant properties of extract was evaluated at three different doses (250, 500 and 1000 mg/kg) in mouse model using phenobarbitone induced sleeping time and rota rod test respectively. Result The ethanol extract of Raphanus caudatus indicated the occurrence of carbohydrates, flavonoids, alkaloids, terpenoids as well as tannins. The extract at highest tested doses i.e. 1000 mg/kg produced significant (p<0.05) sedative action. However, the extract was found to be lacking in muscle relaxant properties at any of tested dose in mice up to 60 days post treatment. Conclusion The study shows that ethanol extract of Raphanus caudatus possess sedative neuro-pharmacological potential and may possibly be used as valuable source of bioactive constituents with psychosedative properties.
    Źródło:
    Acta Poloniae Pharmaceutica - Drug Research; 2019, 76, 5; 855-862
    0001-6837
    2353-5288
    Pojawia się w:
    Acta Poloniae Pharmaceutica - Drug Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Difference in demand for analgesic and sedative medication according to the type of catheter ablation for atrial fibrillation
    Autorzy:
    Koźluk, Edward
    Rzechorzek, Wojciech
    Piątkowska, Agnieszka
    Rodkiewicz, Dariusz
    Opolski, Grzegorz
    Powiązania:
    https://bibliotekanauki.pl/articles/1197576.pdf
    Data publikacji:
    2021-05-26
    Wydawca:
    Gdański Uniwersytet Medyczny
    Tematy:
    analgesia
    atrial fibrillation
    catheter ablation
    conscious sedation
    cryoballoon
    Opis:
    Background: Our aim was to determine if there is a difference in demand for analgesic and sedative medication according to the type of catheter ablation for atrial fibrillation (AF). Material and methods: We collected data from protocols of 1144pts, who underwent ablation of AF. We excluded 275pts, at most due to electrocardioversion during the procedure. We divided them into 4 groups: cryoballoon ablation group (CB, n = 101), single-point radiofrequency ablation group (RFth-, n = 541), single-point radiofrequency ablation group with thermocool catheter (RFth+, n = 156) and Multielectrode Pulmonary Vein Ablation Catheter group (PVAC, n = 71). We used fentanyl and midazolam for pain control. The dose was adjusted by the operator, accord-ing to patients’ request. Results: The median dose of fentanyl 0.04 mg (0.00-0.08) and midazolam 1.00 mg (0.00-2.00) in CB group was lower than in other groups (p < 0.001). The median dose of fentanyl 0.12 mg (0.08-0.17) was lower in RFth- than in in RFth+ group: 0.15 mg (0.1-0.2) (p < 0.001). The demand for analgesia was higher when PVAC was used, with median dose of fentanyl 0.15 mg (0.1-0.2) (p < 0.0024). Conclusions: The demand for analgesic/sedative medication was lower among patients who underwent CB. Among those who underwent RF ablation it was higher in groups with thermocool and multielectrode catheters.
    Źródło:
    European Journal of Translational and Clinical Medicine; 2021, 4, 1; 35-42
    2657-3148
    2657-3156
    Pojawia się w:
    European Journal of Translational and Clinical Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-3 z 3

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