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Wyświetlanie 1-15 z 15
Tytuł:
A study of knowledge attitude practices and identification of perceived barriers towards screening for diabetic retinopathy amongst diabetics in an industrial area in western Maharashtra
Autorzy:
Bakare, Prachi
Sethi, Sejal
Mushtaq, Iqra
Maheshgauri, Rupali
Magdum, Renu
Kamalkishor Modani, Neha
Gogate, Parikshit
Powiązania:
https://bibliotekanauki.pl/articles/29519441.pdf
Data publikacji:
2023-09-30
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
awareness
barriers to diabetic retinopathy screening
diabetic retinopathy screening
knowledge
Opis:
Introduction and aim. Nursing fields begin to face a wide variety of challenges when they first enter clinical practice. The aim of this study is to determine the difficulties experienced in patient communication by nursing students taking the clinical practice course for the first time. Material and methods. Focus group interview design was used for this study. Focus group design is used to give information about the opinions and experiences of the sample group on any subject. It is reported as a convenient design to identify different perspectives on a subject within the scope of the sample. Focus group interviews are a widely used method as data collection technique. Results. The findings of the study continue on 4 main themes at level 3, by identifying the similarities and differences in the codes determined by the three experts (researchers consulted and the researcher conducting/reporting the study). The findings of the study were evaluated in comparison with the findings of the studies reached in the literature and conducted in regions such as Israel, Iran, Sri-Lanka, Kenya, and Africa. Conclusion. There are many problems in student-patient communication in many different dimensions. The difficulties arising due to these problems generally focus on unknown clinical environment, lack of knowledge, differences between theory and practice, and mentor interaction.
Źródło:
European Journal of Clinical and Experimental Medicine; 2023, 3; 539-545
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Exceptional molecular organization of canthaxanthin in lipid membranes
Autorzy:
Sujak, Agnieszka
Powiązania:
https://bibliotekanauki.pl/articles/1039765.pdf
Data publikacji:
2012
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
molecular interactions
retinopathy
lipid membranes
canthaxanthin
Opis:
Canthaxanthin (β,β-carotene 4,4' dione) used widely as a drug or as a food and cosmetic colorant may have some undesirable effects on human health, caused mainly by the formation of crystals in the macula lutea membranes of the retina of an eye. Experiments show the exceptional molecular organization of canthaxanthin and a strong effect of this pigment on the physical properties of lipid membranes. The most striking difference between canthaxanthin and other macular pigments is that the effects of canthaxanthin at a molecular level are observed at much lower concentration of this pigment with respect to lipid (as low as 0.05 mol%). An analysis of the molecular interactions of canthaxanthin showed molecular mechanisms such as: strong van der Waals interactions between the canthaxanthin molecule and the acyl chains of lipids, restrictions to the segmental molecular motion of lipid molecules, modifications of the surface of the lipid membranes, effect on the membrane thermotropic properties and finally interactions based on the formation of the hydrogen bonds. Such interactions can lead to a destabilization of the membrane and loss of membrane compactness. In the case of the retinal vasculature, it can lead to an increase in the permeability of the retinal capillary walls and the development of retinopathy.
Źródło:
Acta Biochimica Polonica; 2012, 59, 1; 31-33
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Troxerutin in the treatment of eye diseases - a proven substance rediscovered
Autorzy:
Bernardczyk-Meller, Jadwiga
Powiązania:
https://bibliotekanauki.pl/articles/23202887.pdf
Data publikacji:
2023-09-30
Wydawca:
Medical Education
Tematy:
diabetic retinopathy
subconjunctival haemorrhage
troxerutin
eye drops
Opis:
Troxerutin is a well and for a long time known substance, it is a semi-synthetic bioflavonoid derived from rutin. Original substance is supplied from flowers of Styphnolobium japonicum tree. The author discusses actual medical effects of troxerutin, including antioxidant, anti-inflammatory, antithrombosis and protecting endothelium of small vessels. Being water-soluble, it can be used as ophthalmic drops in treatment of subconjunctival haemorrhage, vitreous haemorrhage and early stages of diabetic retinopathy.
Źródło:
OphthaTherapy; 2023, 10, 3; 201-204
2353-7175
2543-9987
Pojawia się w:
OphthaTherapy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
AGEs interactions with RAGE and their contribution to diabetic retinopathy
Autorzy:
Solan, Anna
Kempka, Katarzyna
Kamiński, Piotr
Bogdzińska, Maria
Malukiewicz, Grażyna
Powiązania:
https://bibliotekanauki.pl/articles/1075668.pdf
Data publikacji:
2019
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
RAGE
diabetic retinopathy
molecular basis
polimorphism
signaling pathway
Opis:
Diabetic retinopathy as a complication of diabetes is one of the most common causes of vision loss. It is a dangerous disease, which affects more and more people. It is important to know its different causes, background and to generate new, effective therapeutic threatments. One of the possible causes of diabetic retinopathy is the accumulation of advanced glycation products and over-expression of AGEs receptors (RAGE) leading to tissue damage, oxidative stress formation, and the promotion of other changes and disorders. There are many genetic variants that encode the AGEs receptor (RAGE). Some polymorphisms (Gly82Ser, 1704G/T, 2184A/G, -429T/C, -374T/A) may be associated with diabetic retinopathy. This paper aims to systematize knowledge in this field and to show the relationship between these compounds and diabetic retinopathy.
Źródło:
World Scientific News; 2019, 119; 41-51
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Levels of physical activity in people with diabetes residing in Spain
Niveles de actividad física en personas con diabetes residentes en España
Autorzy:
González-Carcelén, Carmen M.
Nicolás López, Jonathan
López Sánchez, Guillermo Felipe
Powiązania:
https://bibliotekanauki.pl/articles/1491126.pdf
Data publikacji:
2020-01-03
Wydawca:
Atena Research Association
Tematy:
Physical activity
Mediterranean diet
Diabetes
Diabetic retinopathy
Spain
Opis:
Objectives: The aim of this study was to analyze the level of physical activity in people with diabetes, depending on their characteristics. Methods: The sample consisted of 81 participants with type 1 and type 2 diabetes and belonging to a diabetes care association. First of all, the participants completed the short version of the International Physical Activity Questionnaire and the Mediterranean Diet Adherence Questionnaire online. Subsequently, they indicated their sex, age, type of diabetes, the presence of other complications and the years since diagnosis. In addition, data on consumption of tobacco and alcohol, glycosylated hemoglobin and fasting glucose were collected. For the analysis of the data, t-test for independent samples was used to compare means between categories, always with a level of significance of p <.05. Furthermore, effect size was calculated through Cohen’s d. Finally, the frequency and the percentage of the variables were calculated. Findings: The results showed in all the categories an average level of physical activity higher than the recommendations of physical activity for people with diabetes, being the level of physical activity predominantly moderate. Although women also complied with the recommendations for physical activity, their level of physical activity was significantly lower than the level of men Conclusions: It is recommended to expand the research on the barriers and motivations found by people with diabetes to practice physical activity, playing special attention to women with diabetes.
Źródło:
Atena Journal of Public Health; 2020, 2; 2-2
2695-5911
Pojawia się w:
Atena Journal of Public Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Barriers to physical activity in people with diabetes residing in Spain
Barreras para la práctica de actividad física en personas con diabetes residentes en España
Autorzy:
Nicolás López, Jonathan
González Carcelén, Carmen M.
López Sánchez, Guillermo Felipe
Powiązania:
https://bibliotekanauki.pl/articles/1491127.pdf
Data publikacji:
2020-01-03
Wydawca:
Atena Research Association
Tematy:
Barriers
Physical activity
Mediterranean diet
Diabetes
Diabetic retinopathy
Spain
Opis:
Objectives: The objective of the present study was to perform an analysis of the barriers to the practice of physical activity and diet in people with diabetes mellitus residing in Spain. Methods: Ninety participants (40 men and 50 women) with type 1 diabetes mellitus (71) and type 2 diabetes mellitus (19) residing in Spain, and aged between 12 and 80 years (average age 41.12 ± 17.04) were part of the present study. The participants were asked about the sociodemographic variables of sex and age, as well as the type of diabetes, the presence of other associated pathologies and the years elapsed since their diagnosis. The participants were also asked about the consumption of tobacco and alcohol. Afterwards, the barriers or difficulties perceived in relation to physical exercise were assessed through the Barriers Self-Report for the Practice of Physical Activity (BSPPA) and the diet with the Questionnaire of Adherence to the Mediterranean Diet (MEDAS-14). Then, the participants provided information regarding their last blood test with respect to the levels of glycosylated hemoglobin (HbA1c) and fasting glucose. A descriptive analysis was carried out to present the characteristics of the sample as well as the barriers for the practice of physical activity presented by the sample studied. Finally, a comparison analysis of means was carried out using the Student's t test for independent samples, showing the significant differences between the barriers for the practice of physical activity according to the characteristics of the sample. Findings: The data showed how the Obligations / Lack of time factor represents the main barrier to the practice of physical activity in this population, especially in women, in those under 65 and in people with type 1 diabetes. Conclusions: In general, it is observed that all those categories that may indicate a less healthy lifestyle have a greater degree of agreement with the perceived barriers.
Źródło:
Atena Journal of Public Health; 2020, 2; 3-3
2695-5911
Pojawia się w:
Atena Journal of Public Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Vitrectomy in stage 5 retinopathy of prematurity - surgical and functional results of 1000 vitrectomies
Autorzy:
Prost, Marek Edmund
Powiązania:
https://bibliotekanauki.pl/articles/2040449.pdf
Data publikacji:
2021-06-23
Wydawca:
Medical Education
Tematy:
retinopathy of prematurity
stage 5
vitrectomy
surgical outcomes
functional results
Opis:
Despite improvements in neonatal care, retinopathy of prematurity is still leading cause of blindness in the world. The most treatment problems pose stage 4 and 5 of this disease. Performing vitrectomy in stage 5 is a subject of controversy among ophthalmologists due to unsatisfactory functional results after the surgery. Therefore, our aim was to present the results of 1000 vitrectomies performed by the author in years 1994–2019 in 1018 eyes of 692 children with stage 5 retinopathy of prematurity. In these children lens sparing vitrectomies and lensectomy-vitrectomy with limbal approach were performed. The results were compared with visual function of 127 untreated children with stage 5 retinopathy of prematurity. Visual acuity of treated patients ranged from 0.05 to no light perception in stage 5 and from no light perception to finger counting in the untreated group. Comparing the functional results of treated and untreated patients, it can be concluded that vitrectomy gives a better chance of gaining useful vision.
Źródło:
OphthaTherapy; 2021, 8, 2; 108-113
2353-7175
2543-9987
Pojawia się w:
OphthaTherapy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Subthreshold micropulse yellow 577 nm laser therapy of diabetic macular oedema in rural and urban patients of south-eastern Poland
Autorzy:
Latalska, Małgorzata
Prokopiuk, Agata
Wróbel-Dudzińska, Dominika
Mackiewicz, Jerzy
Powiązania:
https://bibliotekanauki.pl/articles/989023.pdf
Data publikacji:
2017
Wydawca:
Instytut Medycyny Wsi
Tematy:
diabetic maculopathy
macular edema
laser treatment
micropulse laser
diabetic retinopathy
Opis:
Objectiv. To evaluate the efficacy of subthreshold micropulse yellow (577 nm) laser photocoagulation in diffuse macular edema (DME) in rural and urban patients of south-eastern Poland. Materials and method. Seventy-five eyes of 75 patients with diffuse DME were treated with subthreshold micropulse yellow laser photocoagulation with a 5% duty cycle at an energy level. The laser exposure time was 20 ms and the spot diameter was 100 μm. Best corrected visual acuity (BCVA), reading vision (Snellen) and optical coherence tomography-determined central retinal thickness (CRT) were estimated before and 2, 4 and 6 months after laser treatment. There were no statistically important differences in: the advancement of DME, HbA1c (glycated hemoglobin) level, duration of diabetes mellitus (DM), the degree of vision damage between rural and urban patients. Results. The follow-up was 6 months later. The baseline BCVA was 0.20 and remained stable- 0.3 after 6 months. The Snellen at baseline was 1.0 and improved to 0.5 finally (p=0.0004). The CRT at baseline was 500 μm and changed to 346 μm (p=0.00000) at the final follow-up. Finally, no retinal damage was observed. Conclusions. Place of residence had no statistically significant effect on the demographics data, baseline visual acuity, reading visual acuity and central retinal thickness. Subthreshold micropulse yellow laser showed a highly significant efficiency in the treatment of DME. The effects of the treatment were more significant in rural patients than in urban ones.
Źródło:
Annals of Agricultural and Environmental Medicine; 2017, 24, 1
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The association between ALR2 -106C > T gene polymorphisms and diabetic retinopathy susceptibility in diabetes mellitus patient: a systematic review and meta-analysis
Autorzy:
Putri, Indah Sagitaisna
Rezkita, Bastomy Eka
Irving, Steven
Azmiardi, Akhmad
Powiązania:
https://bibliotekanauki.pl/articles/4175390.pdf
Data publikacji:
2023-03-27
Wydawca:
Medical Education
Tematy:
ALR2 gene
diabetic retinopathy
diabetes mellitus
gene polymorphism
polyol pathway
Opis:
Aldose reductase gene polymorphisms has been indicated to be associated with diabetic retinopathy (DR). The research data were from PubMed and EMBASE. We identified -106C > T single nucleotide polymorphism (SNP). Pool odds ratio (OR) with 95% CI were calculated. Nine studies were included. ALR2 106C > T gene polymorphisms was associated with the increased risk of DR in T1DM (C vs. T, OR = 2.07, p = 0.001; CC vs. CT + TT, OR = 2.56, p = 0.005). T allele and TT genotype were associated with decreased risk of DR in T1DM (OR = 0.48, p = 0.0001 and OR = 0.12, p = 0.0005). In conclusion, C allele and CC genotype may be a risk factor, while T allele and TT genotype may serve as protective factor for DR in T1DM patient.
Źródło:
OphthaTherapy; 2023, 10, 1; 12-21
2353-7175
2543-9987
Pojawia się w:
OphthaTherapy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The way it was and the way it should be - the new approach to the treatment of nonproliferative diabetic retinopathy
Jak nie było, a jak powinno być – nowe podejście do leczenia nieproliferacyjnej retinopatii cukrzycowej
Autorzy:
Misiuk-Hojło, Marta
Kręcicka, Julia
Powiązania:
https://bibliotekanauki.pl/articles/2046661.pdf
Data publikacji:
2021-12-06
Wydawca:
Medical Education
Tematy:
sulodexide
diabetes
diabetic retinopathy
microangiopathy
glycocalyx
sulodeksyd
cukrzyca
retinopatia cukrzycowa
mikroangiopatia
glikokaliks
Opis:
Diabetes has been declared an epidemic of the XXIst century by the World Health Organisation. Diabetic retinopathy, one of its main complications, is a leading cause of vision impairment among professionally active adults. Diabetic retinopathy is a microangiopathy that affects mainly small vessels, due to their highest vulnerability to hyperglycemia. Preventive measures involve mainly strict diabetic follow-ups, balanced level of glycated hemoglobin, blood pressure values and analysis of lipids. Regular ophthalmological check-ups and imaging tests of the retina are also extremely significant. For many years scientists have searched for a therapy to suppress vascular changes in diabetes. In May 2021 a stance on sulodexide use as a supporting treatment in mild and intermediate diabetic retinopathy was published by the Polish Society of Ophthalmology. Sulodexide protects vascular endothelium, contributes to endothelial cells’ function and has profibrinolytic, anti-inflammatory and vasoregulatory properties. These features make it a promising protective agent in the early stages of diabetic retinopathy.
Cukrzyca została uznana przez Światową Organizację Zdrowia za epidemię XXI w. Retinopatia cukrzycowa należy do głównych komplikacji cukrzycy i wiodących przyczyn utraty wzroku wśród aktywnych zawodowo dorosłych. Jest to mikroangiopatia, w której dochodzi do uszkodzenia głównie drobnych naczyń, ponieważ są one najbardziej wrażliwe na hiperglikemię. W ramach działań prewencyjnych kluczowe są adekwatne monitorowanie metaboliczne cukrzycy, w tym wyrównane wartości hemoglobiny glikowanej, ciśnienia tętniczego oraz lipidogramu. Niezwykle ważne są również regularne kontrole okulistyczne i okresowe badania obrazowe siatkówki. Od lat naukowcy poszukują terapii umożliwiającej zahamowanie zmian naczyniowych w cukrzycy. W maju 2021 r. Polskie Towarzystwo Okulistyczne opublikowało stanowisko grupy eksperckiej w zakresie stosowania sulodeksydu jako leczenia wspomagającego w łagodnej oraz średnio zaawansowanej retinopatii cukrzycowej. Sulodeksyd chroni śródbłonek naczyń, wpływa na czynność jego komórek, ma właściwości profibrynolityczne, przeciwzapalne i wazoregulujące. Cechy te czynią go obiecującym czynnikiem protekcyjnym w pierwszych fazach retinopatii cukrzycowej.
Źródło:
OphthaTherapy; 2021, 8, 4; 233-237
2353-7175
2543-9987
Pojawia się w:
OphthaTherapy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Hyperreflective dots in optical coherence tomography
Autorzy:
Paczwa, Katarzyna
Szabelska, Paulina
Rerych, Magdalena
Różycki, Radosław
Gołębiewska, Joanna
Powiązania:
https://bibliotekanauki.pl/articles/2159017.pdf
Data publikacji:
2022-09-30
Wydawca:
Medical Education
Tematy:
hyperreflective dots
HRDs
optical coherence tomography
AMD
diabetic retinopathy
retinal vein occlusion
Opis:
Optical coherence tomography is a non-invasive and repeatable imaging method of posterior segment of the eye used in medical practice. Hyperreflective dots visible in OCT scans have been reported in various retinal diseases such as age-related macular degeneration, diabetic macular edema, retinal vein occlusion and central serous chorioretinopathy. In the future, HRDs may become a useful biomarker in making treatment decision and monitoring ocular conditions among the patients with mentioned diseases.
Źródło:
OphthaTherapy; 2022, 9, 3; 175-179
2353-7175
2543-9987
Pojawia się w:
OphthaTherapy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Macrophages in Diabetes Mellitus: A Review on Understanding of Macrophage Function
Autorzy:
Chatterjee, Susraba
Guria, Srikanta
Powiązania:
https://bibliotekanauki.pl/articles/1059398.pdf
Data publikacji:
2019
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
Alloxan
Beta-cell Therapy
Cytokines
Diabetes mellitus
Diabetic Nephropathy
Diabetic Retinopathy
Macrophage
Macrophage Type 1
Macrophage Type 2
Streptozotocin
Opis:
Diabetes mellitus (DM) causes millions of deaths all over the world. Immune system contains macrophages that play very important role in DM. Excessive secretion of different cytokines can induce the DM development. Diabetes mellitus (DM) also affect the function of macrophage. We review the important findings regarding the role of macrophage in DM. This review may emphasize future direction towards development of novel immune-modulatory therapeutic intervention.
Źródło:
World Scientific News; 2019, 134, 2; 319-325
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Eye Problems on Expeditions – Recommendation of the Medical Commission of the Union Internationale des Associations d’Alpinisme (UIAA)
Autorzy:
Morris, D.S.
Potts, J.
Mella, S.
Depla, D.
Powiązania:
https://bibliotekanauki.pl/articles/2098013.pdf
Data publikacji:
2020-12-04
Wydawca:
Państwowa Wyższa Szkoła Zawodowa w Tarnowie
Tematy:
wyprawa
duża wysokość
wzrok
ślepota śnieżna
cukrzyca
jaskra
retinopatia
expedition
high altitude
vision
snow blindness
diabetes
glaucoma
high altitude retinopathy
Opis:
Visual loss in the wilderness setting is potentially fatal. Firstly it may be a warning sign of a serious systemic problem and secondly the patient may lose their functional independence and ability to respond to objective danger. The issues discussed in this paper fall broadly into two categories, those that are unique to the high altitude setting and those that could happen anywhere but require treatment to protect vision then standard ophthalmological care is unavailable. The aims are to provide practical knowledge on how to manage simple eye problems and also how to recognize the warning signs when evacuation may be required. In keeping with all wilderness medicine, preparation and prevention are essential to avoid eye problems in the mountains. This paper is intended for physicians, interested non-medical people and expedition operators as a practical guide to the treatment and prevention of eye problems on expeditions.
Źródło:
Health Promotion & Physical Activity; 2020, 13, 4; 1-7
2544-9117
Pojawia się w:
Health Promotion & Physical Activity
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The most common eye disease in cat
Choroby oczu występujące często u kotów
Autorzy:
Trbolova, A.
Powiązania:
https://bibliotekanauki.pl/articles/9971.pdf
Data publikacji:
2011
Wydawca:
Okulistyka Weterynaryjna
Tematy:
cat
animal disease
eye disease
agenesia
ankyloblepharon
coloboma
neoplasia
cornea disease
herpetic keratitis
keratitis
sequestrum
uveitis
hypertension
taurine deficiency retinopathy
Opis:
Wiele chorób oczu kotów różni się od tych które spotykamy u inny gatunków zwierząt. Typowo kocim schorzeniem jest sequestrum czyli martwak rogówki. Ogólne objawy ze strony oczu kota są zwykle powiązane z istnieniem choroby systemowej, toczącej się w całym organizmie (choroby tła wirusowego, pasożytnicze, grzybice, nadciśnienie). Oczy kotów wrażliwe są na niedobory tauryny  czy też tiaminy, które to powodują zmiany chorobowe dna oka prowadzące do ślepoty. Bardzo często spotykamy u kotów nowotwory, które są zwykle bardziej agresywne niż u innych gatunków zwierząt. Ponadto występują też schorzenia o podłożu genetycznym i wady rozwojowe.
Źródło:
Okulistyka Weterynaryjna. e-kwartalnik dla lekarzy i studentów weterynarii; 2011, 2
2082-9256
Pojawia się w:
Okulistyka Weterynaryjna. e-kwartalnik dla lekarzy i studentów weterynarii
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Obrazowanie naczyń pozagałkowych w retinopatii cukrzycowej metodą ultrasonografi i dopplerowskiej w kolorze
Color Doppler imaging of the retrobulbar vessels in diabetic retinopathy
Autorzy:
Pauk-Domańska, Magdalena
Walasik-Szemplińska, Dorota
Powiązania:
https://bibliotekanauki.pl/articles/1058042.pdf
Data publikacji:
2014
Wydawca:
Medical Communications
Tematy:
color Doppler ultrasonography
diabetic retinopathy
ophthalmic artery
pulsed Doppler ultrasonography
tętnica ocznadiabetes complications
doppler spektralny
powikłania cukrzycy
retinopatia cukrzycowa
ultrasonografia dopplerowska w kolorze
Opis:
Diabetes is a metabolic disease characterized by elevated blood glucose level due to impaired insulin secretion and activity. Chronic hyperglycemia leads to functional disorders of numerous organs and to their damage. Vascular lesions belong to the most common late complications of diabetes. Microangiopathic lesions can be found in the eyeball, kidneys and nervous system. Macroangiopathy is associated with coronary and peripheral vessels. Diabetic retinopathy is the most common microangiopathic complication characterized by closure of slight retinal blood vessels and their permeability. Despite intensive research, the pathomechanism that leads to the development and progression of diabetic retinopathy is not fully understood. The examinations used in assessing diabetic retinopathy usually involve imaging of the vessels in the eyeball and the retina. Therefore, the examinations include: fl uorescein angiography, optical coherence tomography of the retina, B-mode ultrasound imaging, perimetry and digital retinal photography. There are many papers that discuss the correlations between retrobulbar circulation alterations and progression of diabetic retinopathy based on Doppler sonography. Color Doppler imaging is a non-invasive method enabling measurements of blood fl ow velocities in small vessels of the eyeball. The most frequently assessed vessels include: the ophthalmic artery, which is the fi rst branch of the internal carotid artery, as well as the central retinal vein and artery, and the posterior ciliary arteries. The analysis of hemodynamic alterations in the retrobulbar vessels may deliver important information concerning circulation in diabetes and help to answer the question whether there is a relation between the progression of diabetic retinopathy and the changes observed in blood fl ow in the vessels of the eyeball. This paper presents the overview of literature regarding studies on blood fl ow in the vessels of the eyeball in patients with diabetic retinopathy.
Cukrzyca jest chorobą metaboliczną, charakteryzującą się podwyższonym poziomem glukozy we krwi na skutek nieprawidłowego wydzielania lub działania insuliny. Przewlekła hiperglikemia prowadzi do zaburzeń w funkcjonowaniu wielu narządów oraz do ich uszkodzenia. Zmiany w naczyniach należą do najczęściej spotykanych późnych powikłań cukrzycy. Uszkodzenia typu mikroangiopatii występują w gałce ocznej, nerkach i układzie nerwowym. Makroangiopatia dotyczy naczyń wieńcowych oraz obwodowych. Retinopatia cukrzycowa jest najczęstszym powikłaniem z grupy mikroangiopatii, charakteryzującym się zamknięciem drobnych naczyń siatkówki wraz z ich przeciekiem. Mimo intensywnych badań patomechanizm prowadzący do rozwoju i progresji retinopatii cukrzycowej nie został do końca poznany. Techniki badania używane w ocenie retinopatii cukrzycowej zazwyczaj obrazują naczynia gałki ocznej oraz siatkówkę. W tym celu wykorzystywane są angiografi a fl uoresceinowa, optyczna koherentna tomografi a siatkówki, badanie ultrasonografi czne w prezentacji B, perymetria, cyfrowa fotografi a siatkówki. Istnieje wiele prac analizujących zależności pomiędzy zmianami w krążeniu pozagałkowym a progresją retinopatii cukrzycowej, oceniane za pomocą ultrasonografi i dopplerowskiej. Obrazowanie techniką kolorowego dopplera jest nieinwazyjną metodą, pozwalającą na pomiary prędkości przepływów w małych naczyniach oczodołu. Najczęściej oceniane są: tętnica oczna, będąca pierwszym odgałęzieniem tętnicy szyjnej wewnętrznej, tętnica i żyła środkowa siatkówki, tętnice rzęskowe tylne. Analiza zaburzeń hemodynamicznych w naczyniach pozagałkowych może dostarczyć wiedzy na temat krążenia w cukrzycy oraz pomóc odpowiedzieć na pytanie, czy istnieje związek między progresją retinopatii cukrzycowej a zmianami w przepływach w naczyniach oczodołowych. Niniejsza praca zawiera przegląd piśmiennictwa dotyczącego badań nad przepływami w naczyniach oczodołowych u pacjentów z retinopatią cukrzycową.
Źródło:
Journal of Ultrasonography; 2014, 14, 56; 28-35
2451-070X
Pojawia się w:
Journal of Ultrasonography
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-15 z 15

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