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Wyszukujesz frazę "pulmonary fibrosis" wg kryterium: Temat


Wyświetlanie 1-5 z 5
Tytuł:
Spatial and temporal variability of idiopathic pulmonary fibrosis cases in Silesian Voivodeship in years 2006–2010
Autorzy:
Niewiadomska, Ewa
Kowalska, Małgorzata
Zejda, Jan E.
Powiązania:
https://bibliotekanauki.pl/articles/2161900.pdf
Data publikacji:
2017-06-19
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
occupational exposure
idiopathic pulmonary fibrosis
maps
incidence rate
descriptive epidemiology
hospitalization rate
Opis:
Objectives Idiopathic pulmonary fibrosis (IPF) (J84.1 by the International Statistical Classification of Diseases and Related Health Problems, 10th revision – ICD-10) is a rare disease of unknown cause. Among many risk factors, occupational exposure to metal dust is enumerated. Because of metal industry concentration in the Silesian Voivodeship, Poland, an attempt of spatial and temporal variability of the idiopathic pulmonary fibrosis occurrence evaluation in 2006–2010 is made. Material and Methods The research is a descriptive analysis. Data of the number of new treated cases and firsttime hospitalization due to idiopathic pulmonary fibrosis in the years 2006–2010 was obtained from the National Health Found (Narodowy Fundusz Zdrowia – NFZ). We also assessed spatial and temporal variability of both rates. Data concerned adults aged ≥ 19 years old inhabited the Silesian Voivodeship. Results The standardized incidence rate due to idiopathic pulmonary fibrosis increased in the study period and was in the range of 2.9–3.8/100 000 population. The highest values of incidence were observed in districts localized in the centre of the Silesian Voivodeship. Conclusions Incidence of idiopathic pulmonary fibrosis is not so high in the Silesian Voivodeship but the number of newly treated cases slightly increased in 2006–2010. Spatial and temporal variability of incidence rates for treated registered cases of idiopathic pulmonary fibrosis in the Silesian Voivodeship was observed. It could be an effect of occupational exposure to metal dust, however, final conclusions need more precise studies to the extent of analytical epidemiology. Int J Occup Med Environ Health 2017;30(4):593–601
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2017, 30, 4; 593-601
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A case of hypersensitivity pneumonitis in a worker exposed to terephthalic acid in the production of polyethylene terephthalate
Autorzy:
Sartorelli, Pietro
d'Hauw, Gabriele
Spina, Donatella
Volterrani, Luca
Mazzei, Maria Antonietta
Powiązania:
https://bibliotekanauki.pl/articles/2116710.pdf
Data publikacji:
2020-01-17
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
asbestos
extrinsic allergic alveolitis
polyethylene terephthalate
terephthalic acid
pulmonary fibrosis
pleural plaques
Opis:
Occupational hypersensitivity pneumonitis (OHP) is an interstitial lung disease caused by sensitization to an inhaled antigen. Polyethylene terephthalate (PET) is mainly used for disposable beverage bottles. A clinical case of hypersensitivity pneumonitis (HP) in a 66-year-old patient in the follow-up as a worker formerly exposed to asbestos is presented. At the first visit in 2012 a diagnosis of asbestosis and pleural plaques was formulated. In 2017 the high resolution computed tomography was performed demonstrating a slight progression of the pulmonary fibrosis, while physical examinations revealed inspiratory crackles on auscultation, and lung function tests showed a decreased diffusing capacity for carbon monoxide. The radiological and histological pictures were compatible with HP. From 1992 to 2013 the patient worked in a chemical company that produced PET for disposable beverage bottles. A diagnosis of OHP was made, and the most likely causative agents were terephthalic acid and dimethyl terephthalate. To the best of the authors’ knowledge, this is the first report of an OHP case in PET production.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2020, 33, 1; 119-123
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Acute exacerbation of idiopathic pulmonary fibrosis after inhalation of a water repellent
Autorzy:
Bennett, David
Bargagli, Elena
Refini, Rosa M.
Pieroni, Maria Grazia
Fossi, Antonella
Romeo, Riccardo
Volterrani, Luca
Mazzei, Maria Antonietta
Rottoli, Paola
Powiązania:
https://bibliotekanauki.pl/articles/2177226.pdf
Data publikacji:
2015-06-03
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
siloxanes
acute exacerbation
idiopathic pulmonary fibrosis
water proof inhalation
occupational exposure
chemical hazard
Opis:
The natural course of idiopathic pulmonary fibrosis (IPF) is unpredictable at the time of diagnosis. Some patients may experience episodes of acute respiratory worsening that have been termed acute exacerbations. A 58-year-old male was admitted to our Emergency Department due to progressive and intense dyspnea and dry cough after accidental inhalation of waterproof’s vapor containing siloxanes. Chest high resolution computed tomography (HRCT) scan showed diffuse and bilateral ground glass attenuation, basal predominant reticular abnormalities and subpleural honeycombing. The patient didn’t know that he suffered from IPF and siloxanes’ inhalation triggered an acute exacerbation of his disease. Clinical course after the inhalation was aggressive and, despite steroids and cyclophosphamide therapy, the patient died 3 months after due to a respiratory failure. Inhalation of water repellents has been associated with an acute onset of respiratory symptoms and acute lung injury; usually, however, the prognosis is commonly good with a complete recovery. Our case is an example of an extremely negative reaction probably because of pre-existing and misdiagnosed IPF. Currently, no literature concerning water repellent inhalation as a trigger of acute exacerbation of IPF is available.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2015, 28, 4; 775-779
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Lung fibrosis and exposure to wood dusts: Two cases report and review of the literature
Zwłóknienie płuc a narażenie na pył drewna – opisy dwóch przypadków i przegląd literatury
Autorzy:
Riccò, Matteo
Powiązania:
https://bibliotekanauki.pl/articles/2164377.pdf
Data publikacji:
2015-11-06
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
samoistne zwłóknienie płuc
zewnątrzpochodne alergiczne zapalenie pęcherzyków płucnych
pylica płuc
pojemność dyfuzyjna płuc
tomografia
idiopathic pulmonary fibrosis
extrinsic allergic alveolitis
pneumoconiosis
pulmonary diffusing capacity
tomography
Opis:
Introduction Increasing evidence suggests that idiopathic pulmonary fibrosis (IPF) occurs more often in subjects previously exposed to wood dusts than in non-exposed subjects. Here we report 2 cases of the IPF among workers prolongedly exposed to high levels of hardwood dusts. Case report The case No. 1: An 83 year-old male former smoker, retired joiner developed mild dyspnoea and chronic dry cough over the period preceding the examination. Pulmonary function tests (PFT) identified a mild restrictive pattern and diffusion capacity for carbon dioxide (CO₂) that was severely impaired (57% of predicted value). High resolution computer tomography (HRCT) identified bilateral, subpleural basal reticular opacities in honeycombing, without any nodules or ground-glass opacities. The case No. 2: A 73 year-old male retired joiner, never smoker, presented a 3-year history of progressive breathlessness and non-productive cough in mild hypoxemia. Pulmonary function tests suggested a moderate restrictive pattern in severely impaired diffusion capacity for CO₂ (54% of predicted value). High resolution computer tomography identified diffuse peripheral reticular opacities and honeycombing of lower fields, with apico-basilar gradient. Both cases received diagnosis of the idiopathic pulmonary fibrosis. Discussion The pulmonary fibrosis is a common feature of several diseases and may be induced by inflammatory disorders following inhalation of organic and inorganic dusts (e.g., asbestos, silica), and several reports suggest that many cases of the IPF may be in fact secondary to occupational dust exposure as in the case reports we present here. Conclusions Occupational exposure to wood dusts may be a risk factor for the IPF. Unfortunately, exposure reconstruction is frequently inconsistent and anamnesis often misses other causes of the pulmonary fibrosis (e.g., extrinsic allergic alveolitis). Med Pr 2015;66(5):739–747
Wstęp Coraz więcej dowodów wskazuje na częstsze występowanie samoistnego zwłóknienia płuc (idiopathic pulmonary fibrosis – IPF) u osób wcześniej narażonych na pyły drewna niż u osób nienarażonych na nie. Niniejszy artykuł przedstawia 2 przypadki IPF u pracowników długotrwale eksponowanych na wysokie stężenia pyłu drewna. Opis przypadków Przypadek nr 1: U 83-letniego mężczyzny, byłego palacza i emerytowanego stolarza, w ciągu 6 miesięcy poprzedzających badanie rozwinęły się lekka duszność oraz przewlekły suchy kaszel. Badania czynnościowe płuc wykazały łagodne zaburzenia wentylacji typu restrykcyjnego oraz poważne upośledzenie dyfuzji dwutlenku węgla (CO₂) (57% wartości prognozowanej), natomiast tomografia komputerowa wysokiej rozdzielczości – obustronne podopłucnowe siateczkowate zacienienia u podstawy płuc w postaci obrazu plastra miodu, bez żadnych guzków ani zacienień typu matowej szyby. Przypadek nr 2: Badania czynnościowe płuc 73-letniego mężczyzny, nigdy nie palącego emerytowanego stolarza, z postępującą od 3 lat dusznością, suchym kaszlem oraz łagodną hipoksemią, wykazały umiarkowane zaburzenia wentylacji typu restrykcyjnego oraz poważne upośledzenie dyfuzji CO₂ (54% przewidywanej wartości), natomiast tomografia komputerowa o wysokiej rozdzielczości – rozproszone obwodowe siateczkowate zacienienia oraz obraz plastra miodu w dolnych polach ze szczytowo-podstawnym gradientem. W obu przypadkach zdiagnozowano samoistne zwłóknienie płuc. Omówienie Zwłóknienie płuc jest wspólną cechą kilku chorób i może być wywołane przez procesy zapalne wskutek wdychania organicznych lub nieorganicznych pyłów (np. azbestu, krzemionki). Wiele doniesień, w tym przedstawione w niniejszej pracy, wskazuje na liczne przypadki IPF, w których etiologii narażenie zawodowe na pyły miało charakter drugorzędny. Wnioski Narażenie zawodowe na pyły drewna jest czynnikiem ryzyka występowania IPF. Niestety odtworzenie rzeczywistej ekspozycji zazwyczaj jest trudne, a przeprowadzany wywiad często pomija pozostałe przyczyny powstania zwłóknienia płuc (np. alergiczne zapalenie pęcherzyków płucnych). Med. Pr. 2015;66(5):739–747
Źródło:
Medycyna Pracy; 2015, 66, 5; 739-747
0465-5893
2353-1339
Pojawia się w:
Medycyna Pracy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Nanomedicine - a boon for respiratory disease management
Autorzy:
Balasubramanian, D.
Lavanya, S.J.
Girigoswami, A.
Girigoswami, K.
Powiązania:
https://bibliotekanauki.pl/articles/24200620.pdf
Data publikacji:
2023
Wydawca:
Stowarzyszenie Komputerowej Nauki o Materiałach i Inżynierii Powierzchni w Gliwicach
Tematy:
nanomedicine
asthma
chronic obstructive pulmonary disease
cystic fibrosis
respiratory diseases
nanomedycyna
astma
przewlekła obturacyjna choroba płuc
mukowiscydoza
choroby układu oddechowego
Opis:
Purpose: Respiratory diseases affect the lungs and other parts of the respiratory system. The respiratory disease affects hundreds of millions of humans, and premature death is observed in nearly four million people yearly. The major cause of the increase in this disease is the increased level of air pollution and higher tobacco usage in public places. Design/methodology/approach: We have used the search engines PubMed and Google Scholar for the keywords Respiratory diseases, Nanomaterials, diagnosis, Nanomedicine, and Target drug delivery; recent and relevant articles are selected for reviewing this paper. Findings: Nanomedicine is a recent field of research that deals with monitoring, repairing, theragnosis, and development of human biological systems at the sub-atomic level, where we utilize engineered nanodevices and nanostructures. The conventional therapeutic strategies designed for respiratory diseases have limited solubility and bioavailability. Moreover, the robust effect of the drugs led to adverse side effects due to their high dose requirement. The local delivery of therapeutic Nanoparticles (NPs) or drug-loaded nano vehicles to the lung is a safe technique for managing various respiratory tract-related diseases like chronic obstructive pulmonary diseases, cystic fibrosis, lung cancer, tuberculosis, asthma, and infection. To overcome the difficulties of conventional treatment with antibiotics and anti-inflammatory drugs, nano-enabled drug delivery, nanoformulations of drugs as well as drug nanoencapsulation have been used recently. In this mini-review, we will discuss the importance and application of nanomedicine for diagnosis, treatment and clinical research involved in the different types of respiratory diseases. Practical implications: Nanomedicine provides an alternative delivery of drugs with the help of various nanocarriers, which enhances controlled drug delivery at the pulmonary region and can be used for treating and diagnosing respiratory diseases in vivo and in vitro studies. Further experiments followed by clinical examination are warranted to prove the potential application of nanomedicine in treating respiratory disease. Originality/value: This mini-review will help the readers and budding scientists apply new methods for developing highly efficient drugs with low side effects and improved targeted sites of action.
Źródło:
Archives of Materials Science and Engineering; 2023, 119, 2; 71--85
1897-2764
Pojawia się w:
Archives of Materials Science and Engineering
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-5 z 5

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