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    Wyświetlanie 1-11 z 11
    Tytuł:
    Nutritional predictors of mortality in prevalent peritoneal dialysis patients
    Autorzy:
    Malgorzewicz, Sylwia
    Chmielewski, Michal
    Kaczkan, Malgorzata
    Borek, Paulina
    Lichodziejewska-Niemierko, Monika
    Rutkowski, Boleslaw
    Powiązania:
    https://bibliotekanauki.pl/articles/1038849.pdf
    Data publikacji:
    2016
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    peritoneal dialysis
    nutritional status
    mortality
    Opis:
    Malnutrition remains one of the major predictors of mortality in peritoneal dialysis (PD) patients. The aim of the study was to evaluate the nutritional status of prevalent PD patients, and to determine the best predictors of outcome among anthropometric and laboratory indices of nutrition. The study included 106 prevalent PD patients from a single university-based unit. Anthropometric assessment at baseline included: body mass, body mass index (BMI), skinfold thickness, lean body mass (LBM), content of body fat (%F), mid-arm muscle circumference (MAMC). Laboratory analysis comprised of albumin and total cholesterol. Additionally, each patient underwent a subjective global assessment (SGA). The patients were followed for 36 months. Survival analyses were made with the Kaplan-Meier survival curve and the Cox proportional hazard model. Following SGA, malnutrition was diagnosed in 30 (28%) patients. Importantly, eight of the malnourished patients (27%) were nevertheless overweight or obese. Body weight and BMI showed complete lack of association with the outcome. In Kaplan-Meier analysis low: LBM, MAMC, albumin and cholesterol were significantly related to mortality. Cox analysis revealed that, following adjustment, LBM below median was independently associated with poor outcome (hazard ratio [HR] 3.15, 95% confidence interval [CI] 1.17-8.49, p=0.02). Moreover, the lowest quartile of total cholesterol showed independent association with mortality (HR 8.68, CI 2.14-35.21, p<0.01). Malnutrition is prevalent in patients undergoing PD, and overweight/obesity does not preclude its appearance. The most valuable nutritional indices in predicting outcome in this cohort were LBM and total cholesterol concentration.
    Źródło:
    Acta Biochimica Polonica; 2016, 63, 1; 111-115
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Nutrition and peritoneal dialysis patients – a review
    Autorzy:
    Kourkouta, L.
    Monios, A.
    Frantzana, E.
    Iliadis, Ch.
    Powiązania:
    https://bibliotekanauki.pl/articles/1917517.pdf
    Data publikacji:
    2015
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    haemodialysis
    renal failure
    Diet
    Peritoneal Dialysis
    nutrition
    Opis:
    Introduction: The Peritoneal Dialysis (PD) is a preferable treatment option of the renal replacement in patients with chronic renal failure (CRF) end stage. Purpose: The purpose of this study was to review of articles published related to the contribution of nutrition to health promotion of patients undergoing haemodialysis.Materials and methods: A review of the Greek and international literature on the subject was Performed through the electronic databases Medline, Google Scholar, Scopus and the Association of Greek Academic Libraries Link (Heal-Link), using as key words the following terms:haemodialysis, renal failure, peritoneal dialysis, nutrition.Most of the articles used in this literature review were recently published. Only few old - dated articles were included in the study and the reason was their significant contribution to the field. The exclusion criteria for the articles were the languages except from English and Greek.Results:Patient’s diet must contain 1.3 g of protein per kilogram of body weight per day. Consumption of foods rich in carbohydrates should be limited. Patients should consume foods with the adequate quantity of phosphorus and potassium. Finally, they should have their sodium levels and fluid intake checked because sodium causes severe thirst that can lead to excessive fluid intake. As a result, the patient experiences swelling, shortness of breath and high blood pressure.Conclusion: Patients who undergo peritoneal dialysis must be checked regularly and pay special attention to their diets.
    Źródło:
    Progress in Health Sciences; 2015, 5, 2; 205-210
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Chemical transformations of glucose in solutions for peritoneal dialysis after sterilization and during storage
    Autorzy:
    Hudz, Nataliia
    Wieczorek, Piotr
    KORZENIOWSKA, Karolina
    Powiązania:
    https://bibliotekanauki.pl/articles/895563.pdf
    Data publikacji:
    2018-08-31
    Wydawca:
    Polskie Towarzystwo Farmaceutyczne
    Tematy:
    peritoneal dialysis
    5-hydroxymethylfurfural
    4-dideoxyglucosone-3-ene
    Opis:
    Abstract: The objective of this work was to estimate glucose degradation products (GDPs) in solutions for peritoneal dialysis (PD) including glucose and sodium lactate based on the change of pH and absorption in UV. Spectrophotometric and pH-metric methods were used to measure glucose degradation and transformation of GDPs in laboratory-made solutions after heat sterilization and during storage. Mechanism of transformations of GDPs in the sterilized solutions for PD during storage and spectral characteristic of 5-HMF were studied. Common features for all the batches of the tested solutions for PD after heat sterilization were reduced pH, increase in the absorbance in the range 200-350 nm and the appearance of λmax at 274-283 nm. This indicated that 3,4-dideoxyglucosone-3-ene (3,4-DGE) and 5-hydroxymethylfurfural (5-HMF) had been formed during heat sterilization. Hypsochromic shift relative to the 5-HMF was explained by a spectral interference of levulinic acid having λmax at 266 nm. The change of pH after sterilization depended on the initial pH (before sterilization) and glucose concentration. During storage at room temperature hypsochromic or slight batochromic shift was observed. The absorbance at 228-230 nm diminished while that at λmax 270.5-280 nm was slightly reduced or even increased depending on the composition of a solution and time of storage. It was established that 5-HMF had two absorption maxima at the wavelengths of 228-229 and 283-284 nm in water medium and the absorbance of 5-HMF at 284 nm followed Beer’s law very well in the range of concentration of 1.91-9.85 mg/L.
    Źródło:
    Acta Poloniae Pharmaceutica - Drug Research; 2018, 75, 4; 875-883
    0001-6837
    2353-5288
    Pojawia się w:
    Acta Poloniae Pharmaceutica - Drug Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Adipokines and parameters of peritoneal membrane transport in newly started peritoneal dialysis patients
    Autorzy:
    Golembiewska, Edyta
    Safranow, Krzysztof
    Ciechanowski, Kazimierz
    Bober, Joanna
    Bogacka, Anna
    Stepniewska, Joanna
    Powiązania:
    https://bibliotekanauki.pl/articles/1039455.pdf
    Data publikacji:
    2013
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    peritoneal dialysis
    serum adiponectin
    serum leptin
    solute transport
    Opis:
    Aim: Adiponectin and leptin are two adipokines playing important roles in the regulation of body weight, appetite, carbohydrate and lipid metabolism. In patients with chronic kidney disease (CKD) adipokines accumulate in serum due to reduced renal clearance. Since adipokines have pleiotropic actions, the adipokine balance may have an impact on peritoneal membrane transport. The aim of this study was to assess whether serum adiponectin and leptin levels were related to peritoneal transport and residual renal function (RRF) in newly started peritoneal dialysis patients. Methods: 25 clinically stable patients, 4 to 6 weeks after the onset of PD, were included in the study. For each patient clinical and laboratory data were reviewed and standard PET test was performed. Serum adiponectin and leptin concentrations were determined and leptin/adiponectin (L/A) ratio was calculated. Results: Serum adiponectin correlated negatively with weight, BMI and glucose concentration. Serum leptin and L/A ratio correlated positively with BMI. Serum adiponectin correlated positively with dialysate to plasma (D/P) creatinine ratio and ultrafiltration in PET test. Serum leptin level and L/A ratio correlated strongly negatively with peritoneal creatinine clearance. Conclusions: Serum adiponectin concentration is positively associated with baseline solute transport. Leptin concentration and L/A ratio are negatively associated with dialysis adequacy in newly started PD patients.
    Źródło:
    Acta Biochimica Polonica; 2013, 60, 4; 617-621
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Mathematical models for evaluation, optimization, and control of artificial kidney therapy
    Autorzy:
    Waniewski, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/332857.pdf
    Data publikacji:
    2002
    Wydawca:
    Uniwersytet Śląski. Wydział Informatyki i Nauki o Materiałach. Instytut Informatyki. Zakład Systemów Komputerowych
    Tematy:
    dializa otrzewnowa
    modelowanie kinetyczne
    phemodialysis
    peritoneal dialysis
    kinetic modeling
    Opis:
    Renal replacement therapy involves the control of body pools of water and electrolytes, and removal of small metabolites (urea, creatinine). The correct estimation of "the dose of therapy" and optimisation of the procedure needs quantification of fluid and solute transport during dialysis as well as evaluation of the distribution and exchange of water and solutes within the body. Mathematical models can combine the general physiological knowledge with information about individual patients yielded by clinical measurements. Many of these models (urea model, sodium model, models of peritoneal transport) have been presented to the community of clinical nephrologists in the form of computer programs often supplemented with on-line measuring devices. However, the debate about their meaning and the search for better methods of their application are still vivid.
    Źródło:
    Journal of Medical Informatics & Technologies; 2002, 3; IP27-39
    1642-6037
    Pojawia się w:
    Journal of Medical Informatics & Technologies
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Serum soluble Klotho protein level is associated with residual diuresis in incident peritoneal dialysis patients
    Autorzy:
    Golembiewska, Edyta
    Safranow, Krzysztof
    Kabat-Koperska, Joanna
    Myślak, Marek
    Ciechanowski, Kazimierz
    Powiązania:
    https://bibliotekanauki.pl/articles/1039572.pdf
    Data publikacji:
    2013
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    residual diuresis
    peritoneal dialysis
    soluble Klotho
    phosphate
    FGF-23
    Opis:
    Aim: Active vitamin D (1,25-dihydroxyvitamin D3), PTH, fibroblast growth factor-23 (FGF-23) and Klotho protein are key regulators of phosphate metabolism. Hyperphosphatemia and increased FGF-23 level in patients with end-stage renal disease are associated with increased morbidity and mortality. The relationships among key regulators of phosphate metabolism are still being investigated. FGF-23, the humoral factor involved in phosphate metabolism, is strongly associated with serum phosphorus level. Klotho, a transmembrane protein expressed primarily in renal tubules, functions as an obligatory co-receptor for FGF-23. The soluble form of Klotho, produced by the shedding of the transmembrane protein, is detectable in body fluids. The purpose of the study was to assess if serum soluble alpha-Klotho level was related to phosphate metabolism parameters and residual renal function (RRF) in incident peritoneal dialysis (PD) patients. Methods: Thirty-five clinically stable patients 4 to 6 weeks after the onset of PD were included in the study. For each patient, clinical and laboratory data were reviewed. Serum phosphorus concentration, urinary and peritoneal phosphate clearance, serum FGF-23 and soluble Klotho protein concentrations were determined. Results: Serum soluble alpha-Klotho was strongly negatively correlated with 24-hour diuresis (Rs = -0.55, p = 0.004) and renal phosphate clearance (Rs = -0.40, p = 0.049), but not with RRF. Conclusions: Serum soluble Klotho protein concentration is inversely related to residual diuresis and renal phosphate clearance in incident PD patients.
    Źródło:
    Acta Biochimica Polonica; 2013, 60, 2; 191-194
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Long-time survival of a female with primary amyloidosis treated by peritoneal dialysis
    Autorzy:
    Grzebalska, Agnieszka M.
    Sak, Jarosław
    Prystupa, Andrzej
    Książek, Andrzej
    Powiązania:
    https://bibliotekanauki.pl/articles/972730.pdf
    Data publikacji:
    2017
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    kidney failure
    peritoneal dialysis
    end-stage renal disease
    Amyloidosis
    Opis:
    Introduction. Amyloidosis, both primary and secondary, is a systemic disease characterized by extracellular deposition of fibrillar protein in vital organs, leading to their injury and even insufficiency. It results in a poor diagnosis, especially for patients with primary amyloidosis. Kidney involvement is typical and usually manifests by proteinuria, mainly nephrotic range, leading to end-stage renal disease (ESRD). Patients with ESRD need renal replacement therapy (RRT). Some data claim that better results and longer patient, survival are observed in peritoneal dialysed rather than in haemodialysed patients. Case report. The case is described of 19-year-old Caucasian woman with primary amyloidosis. Inherited primary amyloidosis with abnormal apolipoprotein A-I was established. The patient was successfully treated with peritoneal dialysis for 87 months. After this period, she was transferred for haemodialysis. Such a long survival time on peritoneal dialysis (PD) in a patient with primary amyloidosis has not been found. It is believed that the lowering of immunoglobulin levels in blood and normalization of total protein in serum effectively removed, through dialysate, the pathological polyclonal proteins. This effect probably also sustained cardio-circulatory sufficiency of the patient and significantly prolonged her survival. Conclusion. Peritoneal dialysis is an effective and recommended method of treatment in patients suffering from primary amyloidosis. Peritoneal dialysis should be the first choice therapy in ESRD patient; contrary to haemodialysis, peritoneal dialysis removes pathological proteins and allows the avoidance of intra-dialytic hypotension.
    Źródło:
    Journal of Pre-Clinical and Clinical Research; 2017, 11, 1; 22-24
    1898-2395
    Pojawia się w:
    Journal of Pre-Clinical and Clinical Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    APPROACH OF THE STATE PHARMACOPEIA OF UKRAINE TO ANALYTICAL PROCEDURES VALIDATION ON THE EXAMPLE OF CHLORIDE IONS ASSAY IN PERITONEAL DIALYSIS SOLUTIONS
    Autorzy:
    Hudz, Nataliia
    Leontiev, Dmytro
    Wieczorek, Piotr P.
    Powiązania:
    https://bibliotekanauki.pl/articles/895322.pdf
    Data publikacji:
    2019-08-30
    Wydawca:
    Polskie Towarzystwo Farmaceutyczne
    Tematy:
    uncertainty
    validation
    solutions for peritoneal dialysis
    chlorides assay
    argentometric method
    Opis:
    The objective of this study was to develop and validate an alternative analytical procedure for the total chloride assay in solutions for peritoneal dialysis (PD). The proposed analytical procedure was validated according to the requirements of the International Conference on Harmonization guideline: Topic ICH Q2(R1) and the approach of the State Pharmacopeia of Ukraine (SPU). The analytical procedure was specific. The linearity of the procedure was evaluated in the concentration range of 76 to 114 mmol/L of chloride ions (80-120 % of the stated content 95 mmol/L) with the regression equation y=1.0029•X-0.2263 and a correlation coefficient of 0.9989. The y-intercept of the regression line did not exceed the maximum permissible value of 2.6. The residual standard deviation (s0=0.65) of the calibration curve met the requirement for max s0 (0.84). The mean recovery was found as 100.07%±0.62 %. The precision study also showed a low value of one-sided 95% confidence limit (∆Z=1.15%) that did not exceed the critical value of 1.6%. The accuracy study also showed that the systematic error had not differed statistically from zero. The developed analytical procedure was also found to be robust and reproducible as contents differences were less 1.6%. The reproducibility studies were conducted with different samples of the same laboratory-made PD solutions in different days and laboratories. The performed studies indicated that the developed analytical procedure is simple, fast and cost-efficient, specific, linear, precise, accurate, and robust. The presented approach could be also applied to the validation of other assay analytical procedures.
    Źródło:
    Acta Poloniae Pharmaceutica - Drug Research; 2019, 76, 4; 635-643
    0001-6837
    2353-5288
    Pojawia się w:
    Acta Poloniae Pharmaceutica - Drug Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Effect of a bicarbonate-buffered peritoneal dialysis solution on clinical and laboratory indices of dialysis adequacy
    Autorzy:
    Chmielewski, Michał
    Bielińska-Ogrodnik, Dorota
    Jagodziński, Piotr
    Lichodziejewska-Niemierko, Monika
    Powiązania:
    https://bibliotekanauki.pl/articles/895747.pdf
    Data publikacji:
    2020-05-29
    Wydawca:
    Gdański Uniwersytet Medyczny
    Tematy:
    peritoneal dialysis
    acid-base balance
    end-stage renal failure
    bicarbonate-based solutions
    Opis:
    Background: Biocompatible fluids were introduced to improve dialysis and patient outcome in end-stage renal disease. However, being buffered with lactate, they may insufficiently correct metabolic acidosis, and lead to changes in peritoneum structure. Bicarbonate buffered fluids might mitigate these complications. The aim of the study was to evaluate the influence of a bicarbonate dialysis fluid on clinical and laboratory indices of dialysis adequacy. Material and methods: 20 prevalent peritoneal dialysis (PD) patients created two groups. One group continued on lactate fluid, the other changed to bicarbonate solution. Clinical and laboratory indices of dialysis adequacy were evaluated at baseline, and at six weeks intervals for 24 weeks. Results: In bicarbonate group, pH was 7.36±0.03, HCO3 22.1±1.8 mmol/l at baseline and 7.36±0.04 and 21.2± 2.3 mmol/l at 24 weeks, while in controls pH equaled 7.35±0.12, HCO3 22.2±1.4 mmol/l, at baseline, and 7.40±0.03, and 22.3±1.8 mmol/l, at 24 weeks, with no significant differences. Dialysis adequacy (urea Kt/V), urine output and dialysis ultrafiltration did not differ between the groups, either at baseline or at study termination. Conclusions: Bicarbonate PD solution appears to be similar to standard fluid in the impact on hydration status and on acid/base balance. Longitudinal studies are needed to assess long-term advantages of these biocompatible solutions.
    Źródło:
    European Journal of Translational and Clinical Medicine; 2020, 3, 1; 11-15
    2657-3148
    2657-3156
    Pojawia się w:
    European Journal of Translational and Clinical Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    A mathematical model for fluid-glucose-albumin transport in peritoneal dialysis
    Autorzy:
    Cherniha, R.
    Stachowska-Piętka, J.
    Waniewski, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/907934.pdf
    Data publikacji:
    2014
    Wydawca:
    Uniwersytet Zielonogórski. Oficyna Wydawnicza
    Tematy:
    fluid transport
    transport in peritoneal dialysis
    nonlinear partial differential equations
    ordinary differential equation
    steady-state solution
    transport płynu
    dializa otrzewnowa
    nieliniowe równanie różniczkowe
    równanie różniczkowe zwyczajne
    Opis:
    A mathematical model for fluid and solute transport in peritoneal dialysis is constructed. The model is based on a three-component nonlinear system of two-dimensional partial differential equations for fluid, glucose and albumin transport with the relevant boundary and initial conditions. Our aim is to model ultrafiltration of water combined with inflow of glucose to the tissue and removal of albumin from the body during dialysis, by finding the spatial distributions of glucose and albumin concentrations as well as hydrostatic pressure. The model is developed in one spatial dimension approximation, and a governing equation for each of the variables is derived from physical principles. Under some assumptions the model can be simplified to obtain exact formulae for spatially non-uniform steady-state solutions. As a result, the exact formulae for fluid fluxes from blood to the tissue and across the tissue are constructed, together with two linear autonomous ODEs for glucose and albumin concentrations in the tissue. The obtained analytical results are checked for their applicability for the description of fluid-glucose-albumin transport during peritoneal dialysis.
    Źródło:
    International Journal of Applied Mathematics and Computer Science; 2014, 24, 4; 837-851
    1641-876X
    2083-8492
    Pojawia się w:
    International Journal of Applied Mathematics and Computer Science
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Rhabdomyolysis induced by lipid-lowering therapy in patients with end-stage renal failure maintained on continuous ambulatory peritoneal dialysis – clinical implications
    Rabdomioliza indukowana lekami hipolipemizującymi u chorych z terminalną niewydolnością nerek leczonych ciągłą ambulatoryjną dializą otrzewnową – wnioski kliniczne
    Autorzy:
    Żywiec, Joanna
    Tomaszewski, Maciej
    Żukowska-Szczechowska, Ewa
    Grzeszczak, Władysław
    Powiązania:
    https://bibliotekanauki.pl/articles/1038909.pdf
    Data publikacji:
    2012
    Wydawca:
    Śląski Uniwersytet Medyczny w Katowicach
    Tematy:
    rhabdomyolysis
    lipid-lowering therapy
    end-stage renal failure
    continuous ambulatory peritoneal dialysis
    side effects
    rabdomioliza
    terapia hipolipemizująca
    objawy uboczne
    terminalna niewydolność nerek
    ciągła ambulatoryjna dializa otrzewnowa
    Opis:
    The cases of rhabdomyolysis induced by lipid-lowering therapy in three patients with end-stage renal failure undergoing continuous ambulatory peritoneal dialysis (CAPD) are presented. In most of the cases, the diagnosis of rhabdomyolysis was not problematic regarding their typical clinical symptoms and laboratory examinations. One patient, presumably due to diabetic neuropathy, did not experience typical muscle pain but only asthenia, abdominal pain and an enhanced serum kinase creatine level. Lipid-lowering drug cessation and intensification of the CAPD scheme were effective in all the cases. In certain cases LDL-apheresis was required. The high frequency of lipid disturbances and an enhanced cardio-vascular risk among CADO patients are reasons for the wide-spread use of lipid-lowering agents in this group of patients. Analysis of potential drug interactions, and diagnostic alertness (with watchful observation of atypical symptoms) are required because of the possibility of rhabdomyolysis occurrence as a side effect of this method. Interruption of lipid-lowering therapy with intensification of the peritoneal dialysis scheme are sufficiently effective treatment of iatrogenic rhabdomyolysis among CAPD patients. Persistent hyperlipidaemia with an individual’s predisposition to myolysis after different lipid-lowering agents remain a therapeutic problem.
    Praca przedstawia przebieg rabdomiolizy wywołanej stosowaniem farmakoterapii hipolipemizującej u trzech chorych ze schyłkową niewydolnością nerek, leczonych nerkozastępczo metodą ciągłej ambulatoryjnej dializy otrzewnowej (CADO). Dwóch chorych prezentowało klasyczne objawy kliniczne rabdomiolizy, co w połączeniu z wynikami badań laboratoryjnych stanowiło oczywistą podstawę rozpoznania. W przypadku trzeciego chorego, prawdopodobnie w efekcie współistniejącej neuropatii cukrzycowej, nie występowały typowe bóle mięśniowe, a jedynie osłabienie mięśni, bóle brzucha i podwyższony poziom kinazy kreatynowej w surowicy. U wszystkich chorych uzyskano poprawę w wyniku odstawienia leku hipolipemizującego i intensyfi kacji schematu dializy otrzewnowej. W wybranych przypadkach w dalszej obserwacji konieczne było zastosowanie LDL-aferezy. Duża częstość występowania zaburzeń lipidowych oraz zwiększone ryzyko schorzeń sercowo-naczyniowych wśród chorych leczonych nerkozastępczo są powodem szerokiego stosowania leków hipolipemizujących w tej grupie osób. Możliwość wystąpienia rabdomiolizy jako powikłania takiego leczenia wymaga od lekarza analizy potencjalnych interakcji lekowych oraz czujności diagnostycznej, w tym bacznej obserwacji atypowej symptomatologii. Przerwanie leczenia hipolipemizującego oraz intensyfi kacja dializy otrzewnowej są wystarczająco efektywnym sposobem leczenia jatrogennej rabdomiolizy u chorych CADO. Problemem terapeutycznym nadal pozostaje utrzymująca się hiperlipidemia, przy równoczesnej osobniczej skłonności do występowania miolizy po różnych preparatach z grupy leków hipolipemizujących.
    Źródło:
    Annales Academiae Medicae Silesiensis; 2012, 66, 4; 71-75
    1734-025X
    Pojawia się w:
    Annales Academiae Medicae Silesiensis
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-11 z 11

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