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Wyświetlanie 1-9 z 9
Tytuł:
Sonographic assessment of the prevalence and evolution of fluid collections as a complication of kidney transplantation
Ultrasonograficzna ocena występowania i ewolucji zbiorników płynowych jako powikłania procedury transplantacji nerki
Autorzy:
Kuczyńska, Maryla
Piasek, Ewa
Światłowski, Łukasz
Kuklik, Ewa
Sobstyl, Jan
Drelich-Zbroja, Anna
Słomka, Tomasz
Pyra, Krzysztof
Furmaga, Olga
Szczerbo-Trojanowska, Małgorzata
Powiązania:
https://bibliotekanauki.pl/articles/1033110.pdf
Data publikacji:
2018
Wydawca:
Medical Communications
Tematy:
kidney transplantation
Opis:
Aim of the study: The aim of this study is to assess the prevalence and evolution of perirenal fluid collections in a group of 488 patients who have undergone kidney transplantation. Material and methods: Sonographic documentation of 488 deceased-donor kidney recipients was evaluated for the prevalence of perirenal fluid collections and their evolution in time, depending on selected demographic features of the patients, time of detection, initial dimensions and precise position of the collection relative to the kidney and the location of the transplanted organ in the right or left iliac fossa. The collected data were used for statistical analysis to determine the strength of the potential relationships. Results: In 146 out of 488 subjects perirenal fluid collections were found. In 1/3 of the patients more than one fluid collection was diagnosed. Over 40% of fluid collections were detected within 10 days from the date of the first scan and 24.11% were detected within 10–20 days from the date of the first scan. The majority of fluid collections were located near the lower pole of the kidney. Perihilar collections were the least common. Collections encapsulating the kidney and subcutaneous collections were the largest in size on average. A statistically significant difference between the size of collections located on the surface and the size of those located near the upper pole of the transplanted kidney was demonstrated. However, no correlation was proven to exist between the persistence of the fluid collection and its position relative to the transplanted kidney and its initial size. Conclusions: The correct evaluation of a fluid collection’s dynamics of development and nature requires periodic follow-up of the recipient, preferably in a single clinical center. Ultrasonography is an inexpensive, non-invasive and repeatable method for the determination of the presence of fluid collections. However, the decision whether treatment is necessary requires the sonographic image to be compared with the laboratory signs of inflammation and biochemical analysis of the contents of fluid collections.
Cel pracy: Celem niniejszego opracowania jest ocena występowania i ewolucji okołonerkowych zbiorników płynowych w grupie 488 pacjentów poddanych operacji transplantacji nerki. Materiał i metody: Dokumentacja ultrasonograficzna 488 biorców nerek od dawców zmarłych została poddana ocenie pod kątem częstości występowania okołonerkowych zbiorników płynowych i ich ewolucji w czasie, w zależności od wybranych cech demograficznych pacjenta, czasu wykrycia, początkowych rozmiarów i dokładnej lokalizacji zbiornika względem nerki oraz umiejscowienia przeszczepionego narządu – w prawym lub lewym dole biodrowym. Zgromadzone dane wykorzystano do analizy statystycznej w celu określenia siły ewentualnych zależności. Wyniki: U 146 na 488 badanych stwierdzono obecność okołonerkowych zbiorników płynowych, przy czym u niemal 1/3 pacjentów zdiagnozowano więcej niż jeden zbiornik. Przeszło 40% zbiorników wykryto przed upływem 10 dni od daty pierwszego badania,a 24,11% –w okresie 10–20 dni od daty pierwszego badania. Najwięcej kolekcji płynowych było zlokalizowanychw okolicy bieguna dolnego nerki. Najrzadziej występowały zbiorniki okołownękowe. Największy średni rozmiar osiągały zbiorniki opłaszczające nerkęi leżące podskórnie. Wykazano istotną statystycznie różnicę pomiędzy wymiarami zbiorników zlokalizowanych powierzchniowo orazw okolicy bieguna górnego przeszczepionej nerki. Nie dowiedziono jednak istnienia korelacji pomiędzy trwałością zbiornikaa jego lokalizacją względem przeszczepionej nerki lub początkowym wymiarem. Wnioski: Prawidłowa ocena dynamiki rozwojui charakteru zbiornika płynowego wymaga okresowej kontroli biorcy,najlepiejw jednym ośrodku klinicznym. Ultrasonografia jest tanią, nieinwazyjnąi powtarzalną metodą oceny występowania kolekcji płynowych. Decyzjao potrzebie leczenia wymaga jednak odniesienia obrazu sonograficznego do parametrów zapalnych oraz wyników analiz biochemicznych zawartości zbiorników.
Źródło:
Journal of Ultrasonography; 2018, 18, 73; 126-132
2451-070X
Pojawia się w:
Journal of Ultrasonography
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Surgical Procedures Not Connected with Transplantation in Patients After Kidney or Kidney and Pancreas Transplant with Stable Function of Graft
Autorzy:
Kałuża, Bernadetta
Ziobrowski, Ireneusz
Durlik, Marek
Powiązania:
https://bibliotekanauki.pl/articles/1396724.pdf
Data publikacji:
2012-04-01
Wydawca:
Index Copernicus International
Tematy:
kidney transplantation
kidney and pancreas transplantation
complication
Opis:
The aim of the study was to evaluate complication during and after surgical procedure without connection with transplantation among patients after kidney, kidney and pancreas transplantation with stable function of graft.Material and methods. 54 patients underwent 62 surgical procedures without connection with transplantation procedure. Main characteristic: standard immunosuppressive treatment, main age 51.1±13.95 years, men 77.4%, hospitalization time 5.27±3.31 day, group 1 - 55 procedures among patients after kidney transplantation, group 2 - 7 procedure among patients after kidney and pancreas transplantation.Results. Procedures from general surgery comprised 60% [cholecystectomy 19 (51%), left hemicolectomy 1 (3%), esophagus removal 1 (3%), hernia repair 8 (22%), nefrectomy 3 (8%), pancreas transplantation in patients with functional renal graft 1 (3%), laparotomy 4 (11%), vascular surgery 27% (correction of arteriovenosus fistula 13 (76%), by-pass surgery 1 (6%), embolectomy 1 (6%), implantation of aortal - iliac stentgraft 1 (6%), surgery of iliac artery 1 (6%)]. There has been no difference between parameters measured before and after procedure: creatinine (p=0.93), GFR (p=0.07), urea (p=0.25), glycaemia (p=0.322), glycated hemoglobin (p=0.3), C-peptide (p=0.3). In both groups were no differences in levels of creatinine (p=0.78) and urea (p=0.23), measured in the next years after surgical procedure. Mortality 0%, lost of graft 0%, in - hospital morbidity 10 (16.2%) (hematoma 1.6%, endocavitary electrode 1.6%, wound healing defect 16.2%). Morbidity in group 1 - 12.7%, group 2 - 48.8%, p=0.04.Conclusions. Surgical procedures performed in a specialist center do not impaire prognosis of patients with stable function of graft, after kidney, kidney and pancreas transplantation.
Źródło:
Polish Journal of Surgery; 2012, 84, 4; 196-201
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Aliskiren reduces albuminuria after kidney transplantation
Autorzy:
Tylicki, Leszek
Debska-Slizien, Alicja
Lizakowski, Slawomir
Przybylska, Milena
Heleniak, Zbigniew
Renke, Marcin
Chamienia, Andrzej
Biedunkiewicz, Bogdan
Rutkowski, Przemyslaw
Małgorzewicz, Sylwia
Rutkowski, Boleslaw
Powiązania:
https://bibliotekanauki.pl/articles/1038634.pdf
Data publikacji:
2017
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
albuminuria
aliskiren
kidney transplantation
renoprotection
Opis:
Background: The renoprotective effects of the direct renin inhibitor, aliskiren, in renal transplant recipients have been supposed, but not finally proven. We performed an exploratory double-blind, losartan controlled, cross-over study to evaluate the influence of aliskiren, direct renin inhibitor, on albuminuria and other surrogate markers of kidney injury in patients after renal transplantation. The safety of this therapy was also evaluated. Method: 16 of 18 patients (12 M, 4 F), 48.3 ± 9.0 years, 57.7 ± 9.1 months after kidney transplantation, with hypertension and stable serum creatinine 1.4 ± 0.08 mg/dl without proteinuria, completed the protocol. Each patient underwent two 8-week treatment periods (one with 150 mg of aliskiren, and one with 50 mg of losartan) in random order, allowing an 8-week placebo washout between them. Results: There were no differences in albuminuria, transforming growth factor β-1 and 15-F2t-isoprostanes urine excretion between aliskiren and losartan. Creatinine serum level, eGFR, 24 h systolic and 24 h diastolic blood pressure were stable through the study. There were no differences in haemoglobin and potassium serum concentration between studied drugs. Conclusion: Aliskiren decreases albuminuria in renal transplant recipients with clinically minimal side effects. The effect does not differ from that of losartan.
Źródło:
Acta Biochimica Polonica; 2017, 64, 2; 221-226
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Red blood cell and plasma glutathione peroxidase activities and selenium concentration in patients with chronic kidney disease: A review
Autorzy:
Zachara, Bronisław
Gromadzińska, Jolanta
Wąsowicz, Wojciech
Zbróg, Zbigniew
Powiązania:
https://bibliotekanauki.pl/articles/1041155.pdf
Data publikacji:
2006
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
hemodialysis
selenium
kidney transplantation
glutathione peroxidase
chronic kidney disease
antioxidants
plasma
Opis:
The metabolism of oxygen in aerobic organisms leads to generation of reactive oxygen species (ROS). These entities are able to oxidize almost all classes of macromolecules, including proteins, lipids and nucleic acids. The physiological level of ROS is usually regulated by antioxidant defense mechanisms. There are at least three groups of antioxidant enzymes: superoxide dismutases, catalases and glutathione peroxidases (GSH-Pxs) which neutralize ROS. The trace elements (copper, zinc and selenium) bound to the active sites of the above listed enzymes play an important role in the antioxidant defense system. In mammals, a major function of selenium (Se) and Se-dependent GSH-Pxs is to protect cells from oxidative stress. Selenium concentrations and GSH-Px activities are altered in blood components of chronic kidney disease (CKD) patients. The Se level is frequently lower than in healthy subjects and the concentration very often decreases gradually with advancing stage of the disease. Studies on red cell GSH-Px activity in CKD patients reported its values significantly lower, significantly higher and lower or higher, but not significantly as compared with healthy subjects. On the other hand, all authors who studied plasma GSH-Px activity have shown significantly lower values than in healthy subjects. The degree of the reduction decreases gradually with the progression of the disease. High inverse correlations were seen between plasma GSH-Px activity and creatinine level. A gradual decrease in plasma GSH-Px activity in CKD patients is due to the fact that this enzyme is synthesized predominantly in the kidney and thus the impairment of this organ is the cause of the enzyme's lower activity. Se supplementation to CKD patients has a slightly positive effect in the incipient stage of the disease, but usually no effect was observed in end-stage CKD. Presently, kidney transplantation is the only treatment that may restore plasma Se level and GSH-Px activity in patients suffering from end-stage CKD. A few studies have shown that in kidney recipients, plasma Se concentration and GSH-Px activity are restored to normal values within a period of 2 weeks to 3 months following surgery and thus it can be acknowledged that Se supplementation to those patients has a positive effect on plasma GSH-Px activity.
Źródło:
Acta Biochimica Polonica; 2006, 53, 4; 663-677
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Renal tubular acidosis - underrated problem?
Autorzy:
Golembiewska, Edyta
Ciechanowski, Kazimierz
Powiązania:
https://bibliotekanauki.pl/articles/1039734.pdf
Data publikacji:
2012
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
molecular pathophysiology
kidney transplantation
renal tubular acidosis
gene mutations
Opis:
Renal tubular acidosis (RTA) is a hyperchloremic metabolic acidosis characterized by a normal anion gap and normal (or near normal) glomerular filtration rate in the absence of diarrhoea. Inherited isolated forms of renal tubular acidosis are not common. However, they can also be a part of a more generalized tubule defect, like in Fanconi syndrome. In recent years more and more gene mutations have been found which are associated with RTA (mutations in the gene SLC4A4, encoding a Na+-HCO3- cotransporter (NBC-1); in the gene SLC4A1, encoding Cl-/HCO3- exchanger (AE1); in the gene ATP6B1, encoding B1 subunit of H+-ATPase; in the gene CA2 encoding carbonic anhydrase II; and others) and allow better understanding of underlying processes of bicarbonate and H+ transport. Isolated renal tubular acidosis can be frequently acquired due to use of certain drug groups, autoimmune disease or kidney transplantation. As the prevalence of acquired forms of RTA is common, new therapeutic options for the currently used supplementation of oral alkali, are awaited.
Źródło:
Acta Biochimica Polonica; 2012, 59, 2; 213-217
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Prophylactic intra-abdominal drainage following kidney transplantation: a systematic review and meta-analysis
Autorzy:
Zawistowski, Michał
Nowaczyk, Joanna
Domagała, Piotr
Powiązania:
https://bibliotekanauki.pl/articles/1391567.pdf
Data publikacji:
2021
Wydawca:
Index Copernicus International
Tematy:
drainage
kidney transplantation
lymphocele
surgical wound infection
meta-analysis
Opis:
Introduction: An ongoing debate concerns the need for routine placement of prophylactic intra-abdominal drains following kidney transplantation. Aim: We conducted a systematic review and meta-analysis to determine whether such an approach brings any advantages in the prevention of perirenal transplant fluid collection, surgical site infection, lymphocele, hematoma, urinoma, wound dehiscence, graft loss, and need for reoperation. Methods: We conducted a random-effects meta-analysis of non-randomized studies of intervention comparing drained and drain-free adult renal graft recipients regarding perirenal transplant fluid collection and other wound complications. ROBINS-I tool and funnel plot asymmetry analysis were used to assess the risk of bias. Results: Five studies at moderate to critical risk of bias were included. A total of 2094 renal graft recipients were evaluated. Our analysis revealed no significant differences between drained and drain-free patients regarding perirenal transplant fluid collection (pooled odds ratio [OR], 0.77; 95% confidence interval [CI], 0.28–2.17; I 2 = 72%), surgical site infection (OR, 1.64; 95% CI, 0.11–24.88; I 2 = 80%), lymphocele (OR, 0.61; 95% CI, 0.02–15.27; I 2 = 0%), hematoma (OR, 0.71; 95% CI, 0.12–3.99; I 2 = 71%), and wound dehiscence (OR, 0.75; 95% CI, 0.21–2.70; I 2 = 0%). There was insufficient data concerning urinoma, graft loss, and need for reoperation. Conclusions: The available evidence is weak. Our findings show that the use of intra-abdominal drains after kidney transplantation seems to have neither beneficial nor harmful effects on perirenal transplant fluid collection and other wound complications. The present study does not support the routine placement of surgical drains after kidney transplantation. In this systematic review and meta-analysis we summarize the most up-to-date evidence for and against the routine use of intra-abdominal drain following renal transplantation.
Źródło:
Polish Journal of Surgery; 2021, 93, 4; 1-10
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Employment after renal transplantation vs. the health locus of control and the quality of life
Autorzy:
Grubman-Nowak, Marta
Dębska-Ślizień, Alicja
Renke, Marcin
Powiązania:
https://bibliotekanauki.pl/articles/2085670.pdf
Data publikacji:
2022-02-15
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
quality of life
hemodialysis
health locus of control
health behaviors
employment
kidney transplantation
Opis:
ObjectivesThe aim of the presented study was to compare the health locus of control (HLC) between employed and unemployed patients after kidney transplantation (KT), and to investigate the relationship between HLC and the quality of life (QoL).Material and MethodsThe study group consisted of 101 KT patients and the control group of 60 hemodialysis (HD) patients. The applied methods were: the Multidimensional Health Locus of Control Questionnaire (MHLC), the WHO Quality of Life Questionnaire (WHOQoL-BREF), and a survey collecting information on the socio-demographic status and work experience.ResultsOverall, 57.5% of KT patients were employed and 42.5% were unemployed. In the HD group, 25% were employed and 71% were unemployed, while 4% did not disclose their employment status. The unemployed KT patients, in comparison with the employed ones, presented a higher feeling of the impact of chance on their health (unemployed M±SD 23.68±6.59; employed M±SD 21.02±4.57) and a lower level of QoL on the Somatic Scale (unemployed Me = 14.00, IQR = 3.00; employed Me = 1450, IQR = 3.00) and the Environmental Scale (unemployed M±SD 15.39±2.83; employed M±SD 16.85±3.24). In the employed KT group, the Internal Control Scale (MHLC) correlated with all QoL scales (the Somatic Scale: r = 0.292, p = 0.036; the Psychological Scale: r = 0.455, p = 0.001; the Social Scale: r = 0.304, p = 0.029; and the Environmental Scale: r = 0.307, p = 0.027). In the unemployed KT group, the Internal Control Scale (MHLC) correlated significantly with the Somatic Scale (r = 0.396, p = 0.013) and the Psychological Scale (r = 0.374, p = 0.019).ConclusionsThe employed KT patients have a higher level of independence, with results indicating a strong internal type. Additionally, the working patients assess their QoL better, both in terms of their health condition and the organization of satisfying environment. The obtained knowledge about the psychological characteristics of KT patients may be useful for the occupational activation programs and psycho-education for those with weaker predispositions.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2022, 35, 1; 53-62
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Application of web services architecture to information system for coordination of kidney transplantation
Autorzy:
Wandachowicz, W.
Filutowicz, Z.
Powiązania:
https://bibliotekanauki.pl/articles/333101.pdf
Data publikacji:
2003
Wydawca:
Uniwersytet Śląski. Wydział Informatyki i Nauki o Materiałach. Instytut Informatyki. Zakład Systemów Komputerowych
Tematy:
koordynacja procesu
obliczenia rozproszone
przeszczep nerek
technologia internetowa
architektura usług internetowych
process coordination
distributed computing
kidney transplantation
internet technology
web services architecture
Opis:
Cooperation Supporting System (CSS) is a project with one goal of prevailing importance: to improve information exchange between all participants of the kidney transplantation process. The project designed for the Regional Dialysis and Transplantation Centre in N. Copernicus Hospital in Łódź is carried on by the Artificial Intelligence and Software Engineering team of Institute of Computer Science. Since kidney transplantation engages many institutions, quick and effective flow of information plays a key role in the whole process. Given the current state of the system and the new concepts of its development, we decided to restructure the communication layer of the system. The present paper discusses how this change influences the overall system design, capabilities of the system, possibilities of future enhancements as well as possible integration with other information systems. To this purpose, the Web Services standard is presented and a brief overview of the evolution of distributed computing technologies is also given.
Źródło:
Journal of Medical Informatics & Technologies; 2003, 5; MI137-145
1642-6037
Pojawia się w:
Journal of Medical Informatics & Technologies
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Patient care after heart and kidney transplantation - case report
Autorzy:
Brzozowski, A.
Jaroszynski, A.
Powiązania:
https://bibliotekanauki.pl/articles/3321.pdf
Data publikacji:
2014
Wydawca:
Instytut Medycyny Wsi
Tematy:
human disease
transplantation
patient
care
heart
kidney
therapy
immunosuppressive therapy
transplant
rejection risk
Źródło:
Journal of Pre-Clinical and Clinical Research; 2014, 08, 1
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-9 z 9

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