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Wyszukujesz frazę "immunosuppression" wg kryterium: Temat


Wyświetlanie 1-6 z 6
Tytuł:
Immunosuppressive influence of Anguillid herpesvirus-1 (AngHV-1) infection on cellular defense mechanisms in European eel (Anguilla anguilla)
Autorzy:
Schulz, P.
Deperasińska, I.
Kaczorek-Łukowska, E.
Siwicki, A.K.
Powiązania:
https://bibliotekanauki.pl/articles/2087405.pdf
Data publikacji:
2019
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
alloherpesviruses
cellular immunity
immunosuppression
innate immunity
Źródło:
Polish Journal of Veterinary Sciences; 2019, 4; 785-787
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Immunosuppression during Leishmania donovani infection: a potential target for the development of therapy
Autorzy:
Flora, R.
Aghazadeh-Dibavar, S.
Bandyopadhyay, M.
Dasgupta, S.
Powiązania:
https://bibliotekanauki.pl/articles/5556.pdf
Data publikacji:
2014
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
immunosuppression
Leishmania donovani
parasite
infection
therapy
leishmanial infection
leishmaniasis
Opis:
Dysfunction of T-helper 1 mediated immune responses is a hallmark of the progression of visceral leishmaniosis (VL). Several factors such as altered antigen presentation, and abnormalities in MHC/HLA, antigen processing, and T cell receptor recognition regulate the onset of immunosuppression. Recent investigations on VL patients suggest that susceptibility to visceral leishmaniosis is genetically determined and varies between populations in different geographical locations. Emerging evidence also indicates the importance of the role played by myeloid derived suppressor cells in progressive VL. This study provides a mechanistic view of means to target the signaling mechanisms of immunosuppression to determine potential therapeutic interventions.
Źródło:
Annals of Parasitology; 2014, 60, 4
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Search for new synthetic immunosuppressants II. Tetrazole analogues of hymenistatin I.
Autorzy:
Zubrzak, Paweł
Kociołek, Karol
Smoluch, Marek
Silberring, Jerzy
Kowalski, Marek
Szkudlińska, Barbara
Zabrocki, Janusz
Powiązania:
https://bibliotekanauki.pl/articles/1044066.pdf
Data publikacji:
2001
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
immunosuppression
cis-amide bond
1,5-disubstituted tetrazole ring
hymenistatin I
Opis:
Linear and cyclic hymenistatin I (HS I) analogues with dipeptide segments Ile2-Pro3, Pro3-Pro4 and Val6-Pro7 replaced by their tetrazole analogues Ile-Ψ[CN4]-Ala3, Pro3-Ψ[CN4]-Ala4 and Val6-Ψ[CN4]-Alawere synthesized by the solid phase peptide synthesis method and cyclized with the TBTU and/or HATU reagent. The peptides were examined for their immunosuppressive activity in the lymphocyte proliferation test (LPT).
Źródło:
Acta Biochimica Polonica; 2001, 48, 4; 1151-1154
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Conjunctival herpetic ulcer in an immunosuppressed patient with birdshot chorioretinopathy
Autorzy:
Fernández-Hortelano, Ana
Guzmán-Almagro, Elena
Rebollo, María Castro
Rodríquez, Carlos Izquierdo
Martín-Moro, Julio González
Powiązania:
https://bibliotekanauki.pl/articles/2042908.pdf
Data publikacji:
2021-08-27
Wydawca:
Medical Education
Tematy:
conjunctival ulcers
herpetic keratitis
Herpes simplex virus
birdshot chorioretinopathy
immunosuppression
topical steroids
Opis:
Introduction: Herpes Simplex Virus (HSV) is a human herpesvirus responsible for systemic infections. Ocular involvement spans all ocular tissues. Corneal lesions, such as dendritic or geographic ulcers, are frequently found in HSV keratitis while conjunctival lesions have been described as infrequent. Clinical case: A 62-year-old man diagnosed with Birdshot chorioretinopathy presented a stye in his eyelid that was treated with oxytetracycline-hydrocortisone ointment. One week later he returned presenting several small dendritic corneal ulcers in both eyes and a conjunctival ulcer in one of them. All lesions healed completely after treatment with topical acyclovir ophthalmic ointment at 3%. Conclusions: We should pay attention to the conjunctiva and not merely focus on the cornea when examining patients with herpetic eye disease, especially if being treated with inmunosupressors.
Źródło:
OphthaTherapy; 2021, 8, 3; 175-178
2353-7175
2543-9987
Pojawia się w:
OphthaTherapy
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Antifungal effect of Satureja khuzestanica Jamzad essential oil on oral candidiasis in immunosuppressed rats
Autorzy:
Najibzadeh, T.
Yadegary, M.H.
Powiązania:
https://bibliotekanauki.pl/articles/72688.pdf
Data publikacji:
2018
Wydawca:
Instytut Włókien Naturalnych i Roślin Zielarskich
Tematy:
aromatic plant
Satureja khuzestanica
antifungal effect
essential oil
oral candidiasis
rat
immunosuppression
candidiasis
Opis:
The antimicrobial, antibacterial, antioxidant, antihyperlipidaemic, antidiabetic, anti-inflammatory and analgesic effects of Satureja khuzestanica (Lamiaceae) have been investigated in numerous studies. The antifungal effects of S. khuzestanica essential oil (SKJO) in immunosuppressed rats suffering from oral candidiasis were investigated. A fungal suspension with a density of 3×108 CFU/ml was taken from the isolate of a case with acute vaginitis. In order to achieve a medicinal formulation, accurate twice the minimum inhibitory concentration (MIC) of SKJO and 10 times MIC of nystatin was used with 0.8% agar as a base material. In this study, 35 rats divided into 5 groups each of 7 were used. The assessment of level of infection and specification of the effects of treatment were performed using microbiological and histopathological methods as well as clinical examinations. Our results show that carvacrol is the main compound of SKJ essential oil. Lesions completely disappeared in both treatment groups (SKJO and nystatin) after 8 days of treatment. Furthermore, in groups treated with SKJO and nystatin, the quantities of mean logarithm of colony forming unit (CFU) were 85.62% and 90.62%, respectively, in comparison with placebo group. Also, histopathological properties suggested no infection in groups who had clean and normal dorsal tongue mucosa. Using SKJO with twice accuracy it was concluded that MIC in immunosuppressed rats was quite successful in a time of a week and equal with that of a nystatin treatment with an accuracy of 10 times the MIC.
Źródło:
Herba Polonica; 2018, 64, 3
0018-0599
Pojawia się w:
Herba Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of Biolex Beta-HP on phagocytic activity and oxidative metabolism of peripherial blood granulocytes and monocytes in rats intoxicated by cyclophosphamide
Autorzy:
Wojcik, R
Powiązania:
https://bibliotekanauki.pl/articles/32265.pdf
Data publikacji:
2010
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
beta-1,3-1,6-D-glucan
cyclophosphamide
rat
phagocytic activity
oxidative metabolism
granulocyte
monocyte
flow cytometry
peripheral blood
immunosuppression
blood neutrophil
Opis:
The objective of this study was to determine the effect of ß-l,3/l,6-D-glucan (Biolex-Beta HP) on the phagocytic activity and oxidative metabolism of peripheral blood granulocytes and monocytes in rats intoxicated by cyclophosphamide. The experimental material comprised 40 adult Wistar rats aged 14 weeks, divided into two equal groups, a control group and an experimental group, each of 20 adult rats, including 10 males and 10 females. In the course of 3 successive days, 20 rats from the experimental group were administered cyclophosphamide intramuscularly at a dose of 50 mg/kg body weight/day. On the 8th day of the experiment, 10 control group (K) rats and 10 experimental group (C) rats were sacrificed. Arterial blood samples were collected and diluted with heparin to determine and compare the phagocytic activity (Phatogest) and oxidative metabolism (Bursttest) of peripheral blood granulocytes and monocytes by flow cytometry. Starting on the 8lh day of the experiment, the feed of the remaining 10 rats from the experimental group (C+G) and 10 rats from the control group (G) was supplemented with Biolex-Beta HP at a dose of 50 mg/kg body weight/day for 14 consecutive days. On day 22, arterial blood samples were collected from all (C+G) and (C) group rats, diluted with heparin to determine and compare the phagocytic activity and oxidative metabolism of peripheral blood granulocytes and monocytes by flow cytometry. The results showed that Biolex-Beta HP modulated the phagocytic activity and oxidative metabolism of blood neutrophils and monocytes suppressed by cyclophosphamide in rats. The immunorestoring activity of Biolex-Beta HP was observed in this study.
Źródło:
Polish Journal of Veterinary Sciences; 2010, 13, 1; 181-188
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-6 z 6

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