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Tytuł:
Antiviral drug resistance rates among patients with chronic hepatitis B infection
Autorzy:
Özlük, Suat
Bayram, Yasemin
Özkaçmaz, Ayşe
Parlak, Mehmet
Özdemir, Ayşe
Aypak, Cenk
Powiązania:
https://bibliotekanauki.pl/articles/25102375.pdf
Data publikacji:
2023-06-30
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
antiviral agents
antiviral drug resistance
chronic hepatitis B
hepatitis B
Opis:
Introduction and aim. Chronic hepatitis B infection (CHB) affects millions of people around the world. Many clinicians find it challenging to choose therapeutic agents due to the mutations that occur in the hepatitis B virus (HBV) that cause drug resistance. Thus, the aim of this study was to determine the HBV resistance rates against the currently recommended first-line therapies in the region of our country where HBV prevalence is high. Material and methods. A total of 96 patients (56 men and 40 women) with HBV infection were enrolled in the study. The serum samples collected from those were analyzed with real-time polymerase chain reaction analysis followed by pyrosequencing (PyroStar HBV Drug Resistance Test, Altona Diagnostics, Germany) for drug resistance mutations associated with lamivudine, adefovir, telbivudine, entecavir, and tenofovir. Results. HBV drug-resistance mutations were investigated in 80 treatment-naïve and 16 treatment-experienced patients (6 entecavir, 4 PEGylated-interferon, 4 tenofovir, 2 lamivudine). None of the HBV-DNA samples had mutations cause to drug resistance were detected in any codons regions that were analyzed. Conclusion. Antiviral resistance poses serious obstacles for clinicians in the treatment of CHB. Determining whether antiviral resistance exists in HBV is critical to choose the appropriate treatment agent.
Źródło:
European Journal of Clinical and Experimental Medicine; 2023, 2; 283-288
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Virological response to treatment with peginterferon alfa-2a in adolescents with chronic hepatitis B
Autorzy:
Pawlowska, Małgorzata
Halota, Waldemar
Kozielewicz, Dorota
Jendryczka, Ewa
Powiązania:
https://bibliotekanauki.pl/articles/1039657.pdf
Data publikacji:
2012
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
peginterferon alfa-2a
thrombocytopenia
hepatitis B virus
chronic hepatitis B
Opis:
Background: There are few data on the efficacy and safety of pegylated interferon treatment in adolescents with chronic hepatitis B. Aim: We conducted a pilot study in 13 adolescents with chronic hepatitis B treated with peginterferon alfa-2a at 100 µg/m2 once weekly for 48 weeks. Methods: HBV DNA was assessed by qPCR method. Results: After four weeks of treatment six adolescents had undetectable HBV DNA (<12 IU/mL). Seven adolescents - including five HBV negatives at week 4 - had undetectable HBV DNA (<55 IU/mL) at week 24, and seven adolescents - including all HBV DNA negatives at week 4 - had undetectable HBV DNA at week 48 of treatment (<55 IU/mL). Five adolescents had undetectable HBV DNA (<55 IU/mL) after 24 weeks of follow-up (sustained viral response). HBeAg seroconversion was achieved in one patient. HBsAg loss was documented at the end of therapy in two of the six adolescents HBV DNA negative at week 4 of treatment. Three adolescents withdrew from the treatment (two because of adverse events, one because of withdrawal of parental consent). Leukopenia was reported in seven adolescents and three individuals experienced thrombocytopenia. Except for one patient who discontinued treatment due to leukopenia, no dose modifications for adverse events or laboratory abnormalities were required. Conclusion: This pilot study shows that 48 weeks of treatment with peginterferon alfa-2a can result in sustained HBV DNA suppression, HBeAg seroconversion and HBsAg loss in adolescents with CHB. Larger and longer trials are now required to better define the magnitude of the benefit in this group of patients.
Źródło:
Acta Biochimica Polonica; 2012, 59, 4; 587-591
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The seroprevalence of the hepatitis B virus in Italian medical students after 3 decades since the introduction of universal vaccination
Autorzy:
Sartorelli, Pietro
Occhialini, Federico
Miceli, Rosalia
Pietronigro, Antonella
Bianciardi, Laura
Salini, Chiara
Messina, Gabriele
Powiązania:
https://bibliotekanauki.pl/articles/2085658.pdf
Data publikacji:
2022-02-15
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
hepatitis B
vaccination
medical students
immunization
hepatitis B antibodies
seroepidemiological studies
Opis:
ObjectivesSince 1991 hepatitis B vaccination has been mandatory for all newborns in Italy. The aim of the study was to verify the long-term seroprevalence and the efficacy of hepatitis B vaccination in medical students of the University of Siena.Material and MethodsA cross-sectional observational study was conducted on a population of 850 medical students of the University of Siena (322 males and 528 females, mean age: 23 years) by obtaining from the medical reports the serological analysis data for the total anti-hepatitis B antibodies (HBsAb) and information on hepatitis B vaccination (number of vaccine doses, age at the first vaccination, time since the final vaccination dose, country of origin). Raw odds ratios (ORs) and 95% confidence intervals (CIs) were initially calculated to evaluate the association between 2 variables. The adjusted ORs were then calculated using a multivariate logistic regression model to study the association between the variables and the possible confounding factors.ResultsOverall, 593 students (69.76%) were immunized against hepatitis B, while 257 (30.24%) had HBsAb antibody titer <10 mIU/ml. From the OR calculation, an inverse correlation emerged between seropositivity to hepatitis B and age, and between seropositivity to hepatitis B and the age at the first vaccination dose. There was also a correlation between seropositivity and the number of vaccination doses received. By performing the multivariate logistic analysis, correlations with these variables were confirmed.ConclusionsA significant part of the studied population was not immunized against hepatitis B virus, despite the fact that vaccination had been carried out as prescribed by law. The results of the study reaffirm the importance of health surveillance in subjects at biological risk such as medical students.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2022, 35, 1; 75-80
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Hepatic expression of miR-122 and antioxidant genes in patients with chronic hepatitis B
Autorzy:
Wójcik, Kamila
Piekarska, Anna
Szymańska, Bożena
Jabłonowska, Elżbieta
Powiązania:
https://bibliotekanauki.pl/articles/1038774.pdf
Data publikacji:
2016
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
hepatitis B
antioxidant genes
miR-122
Opis:
Introduction: The pathogenesis of chronic hepatitis B depends on both, the immune response and oxidative stress. Aim of the study: To assess the hepatic expression of miR-122 and the antioxidant genes: HMOX-1, NQO1 and GFER1, in liver biopsy specimens obtained from patients with chronic hepatitis B, with regard to selected clinical and histological parameters, using RT-PCR. Results: The study group comprised 34 HBV-infected patients. Statistically significant associations were found between lower hepatic expression of HMOX-1 and greater severity of liver inflammation (p=0.04). However, significantly higher expression of NQO1 was observed in patients with advanced liver fibrosis (p=0.035). Hepatic expression of miR-122 in HBV patients was not associated with viral load or liver injury. Conclusion: The hepatic expression of HMOX-1and NQO1 may be associated with liver injuries in chronic hepatitis B. However, hepatic expression of miR-122 does not seem to correspond to progression of the liver disease.
Źródło:
Acta Biochimica Polonica; 2016, 63, 3; 527-531
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Neutrophil-lymphocyte ratio and mean platelet volume as predictive factors for liver fibrosis and steatosis in patients with chronic hepatitis B
Autorzy:
Pokora-Rodak, A.
Kiciak, S.
Tomasiewicz, K.
Powiązania:
https://bibliotekanauki.pl/articles/2081973.pdf
Data publikacji:
2018
Wydawca:
Instytut Medycyny Wsi
Tematy:
neutrophil-lymphocyte ratio
hepatitis B
liver fibrosis
liver steatosis
Opis:
Objective. Evaluation of the neutrophil-lymphocyte ratio and mean platelet volume as predictive factors for liver fibrosis and steatosis in HBV patients qualified for antiviral treatment. Materials and method. The study comprised 38 CHB patients who had commenced antiviral treatment, and 20 healthy volunteers who constituted the clinical control group. All patients had their blood count taken and underwent hepatic assessment using transient elastography with CAP (controlled attenuation parameter). Results. It was found that the mean hepatic fibrosis was 8.7 kPa (±8.8) and the mean liver steatosis – 286 db/m (±64). Mean NLR – 2.78(±1.1), whereas in the control group the mean NLR value was 1.64(±0.98). A negative linear correlation (r= -0.34; p=0.035) was found between liver fibrosis and the NLR value in the study group. No correlation was observed between hepatic steatosis and the NLR. Mean MPV – 12.6fl (±3.1), which was considerably higher in the CBH patients than in the control group. A positive correlation (r= 0.79, p= 0.001) was found between MPV and disease severity evaluated with transient elastography. Conclusions. The NLR and the MPV were significantly higher in the CHB patients than in the healthy volunteers. Both the NLR and the MPV can be treated as predictive factors for liver fibrosis in this group of patients.
Źródło:
Annals of Agricultural and Environmental Medicine; 2018, 25, 4; 690-692
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Diagnosis and treatment difficulties in 18-year-old male patient with hereditary hemochromatosis, chronic hepatitis B, Gilbert syndrome and ulcerative colitis
Autorzy:
Sikorska, Katarzyna
Liberek, Anna
Romanowski, Tomasz
Szlagatys-Sidorkiewicz, Agnieszka
Landowski, Piotr
Bielawski, Krzysztof
Powiązania:
https://bibliotekanauki.pl/articles/1039929.pdf
Data publikacji:
2011
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
hereditary hemochromatosis
ulcerative colitis
chronic hepatitis B
Glibert syndrome
Opis:
Among possible causes of chronic hepatitis in adolescents most common are infections, autoimmune disorders and metabolic diseases. Thus, diagnostic procedures should be multidirectional. This study reports diagnosis and treatment difficulties in an 18-year-old male patient with hereditary hemochromatosis (HH), ulcerative colitis (UC), chronic hepatitis B (CHB) and Gilbert syndrome. The presented case illustrates problems in diagnostics related to the presence of numerous disease conditions in one patient. It should be taken into consideration that these diseases coexisting in one patient can mutually affect their symptoms creating specific diagnostic difficulties.
Źródło:
Acta Biochimica Polonica; 2011, 58, 2; 251-254
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Prevalence of hepatitis B virus infection among barbers and their knowledge, attitude and practices in the district of Sukkur, Sindh
Autorzy:
Abbasi, Imran N.
Fatmi, Zafar
Kadir, Muhammad M.
Sathiakumar, Nalini
Powiązania:
https://bibliotekanauki.pl/articles/2178888.pdf
Data publikacji:
2014-10-01
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
hepatitis B
barbers
peri-urban
Sukkur
knowledge
attitude and practices
Opis:
Objectives: Several occupations in developing countries lag behind in ensuring the safety of their workers in occupational settings. Lack of implementation of safety guidelines at workplaces can expose workers to health risks. In Pakistan, barbers are one of the un-regulated occupational groups. Low literacy, increased frequency of direct skin contact and blade/razors use can expose barbers to body fluids including blood of the customers. We conducted this study in order to determine hepatitis B virus (HBV) prevalence among barbers and their knowledge, attitude and practices in a peri-urban district of Sindh. Material and Methods: Three hundred eighty-five barbers from the Sukkur district were interviewed using a structured questionnaire. Blood samples were collected and tested for HBsAg. A scale was built to determine the proportions of responses to knowledge, attitude and practice items. Results: The prevalence of HBV among barbers was 2.1%. The barbers’ knowledge on HBV and its transmission routes was poor. The response to attitude items was good, except that only 35.1% of the participants agreed to have vaccination against HBV. The overall performance on the knowledge and practice scales was poor compared to the attitude scale on which 80% of the barbers performed well. Conclusion: The prevalence of HBV among barbers was lower compared to the available national figures for the prevalence among the general population.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2014, 27, 5; 757-765
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Hepatitis B and C infection: Is it a problem in Polish healthcare workers?
Autorzy:
Rybacki, Marcin
Piekarska, Anna
Wiszniewska, Marta
Walusiak-Skorupa, Jolanta
Powiązania:
https://bibliotekanauki.pl/articles/2179151.pdf
Data publikacji:
2013-06-01
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
healthcare workers
HBV prevalence
HCV prevalence
hepatitis B vaccination
ALT testing
Opis:
Objectives: Hepatitis B (HBV) and C viruses (HCV) are among the most frequent blood borne pathogens. According to WHO, 5% of healthcare workers (in central Europe), are exposed to at least one sharps injury contaminated with HBV per year, 1,7% - contaminated with HCV. Aims: The aims of the study were to determine prevalence of HCV and HBV infections, vaccination efficacy against hepatitis B and usefulness of alanine aminotransferase (ALT) testing in prophylactic examinations in healthcare workers (HCWs). Material and Methods: In a group of 520 healthcare workers, a survey, laboratory and serologic tests such as ALT, HBsAg, anti-HBs, anti-HBcT and anti-HCV were carried out. Results: The study revealed a low rate of workers with presence of HBsAg and anti-HCV (1,2% and 0,8% respectively). Anti-HBcT was found in 99 subjects (19%) without a significant association with experiencing an occupational percutaneous injury. Being vaccinated against HBV was declared by 90% of the subjects. There was no relationship between ALT level rise and positive HBsAg, anti-HCV and anti-HBcT tests. Conclusion: A seroprevalence of HBV and HCV markers in HCWs found in the study is low and similar to the one found in general population. Current or past hepatitis B infections were independent of needle stick injuries. Vaccination against HBV coverage, although found to be high, should improve to 100%. Occupational prophylactic medical examinations found performing ALT test (obligatory in Poland for HCWs) not helpful. It seems that determination of anti-HBcT and anti-HCV status would be essential in pre-employment medical examinations.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2013, 26, 3; 430-439
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The assessment of knowledge about viral hepatitis among Polish society
Autorzy:
Ślusarz, Krystian
Szczygieł, Katarzyna
Sobala-Szczygieł, Barbara
Jaroszewicz, Jerzy
Powiązania:
https://bibliotekanauki.pl/articles/1065218.pdf
Data publikacji:
2019
Wydawca:
Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:
HAV infection
HBV infection
HCV infection
knowledge assessment
viral hepatitis A
viral hepatitis B
viral hepatitis C
Opis:
Viral hepatitis is caused by viruses, the most important of which are hepatitis A virus (HAV), hepatitis B virus (HBV) and hepatitis C virus (HCV). New discoveries and new therapeutic options result in better and better results of treatment. However, the public's awareness of the occurrence of these diseases and the detection of infections as soon as possible is still important, what is associated with better outcomes. In order to assess the basic knowledge about viral hepatitis among Polish society, an online survey spread throughout Poland and covering mainly young people was created. 2205 responses were collected and analyzed. On the basis of the results obtained, it can be concluded that Polish youth have little knowledge about viral hepatitis, what is associated with less awareness of the possibility of infection.
Źródło:
World Scientific News; 2019, 135; 1-13
2392-2192
Pojawia się w:
World Scientific News
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The expression of HBV antigens in transgenic lettuce micropropagated in vitro cultures for the purpose of anti-HBV vaccine
Autorzy:
Czyz, M.
Wyrwa, K.
Bociag, P.
Dembczynski, R.
Marecik, R.
Krajewski, P.
Kapusta, J.
Pniewski, T.
Powiązania:
https://bibliotekanauki.pl/articles/951182.pdf
Data publikacji:
2015
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
conference
hepatitis B virus
vaccine
vaccination
vaccine production
antigen expression
micropropagation
transgenic plant
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2015, 96, 1
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Prevalence of blood-borne viruses among Iranian dentists: Results of a national survey
Autorzy:
Ahmad Akhoundi, Mohammad Sadegh
Momeni, Nafiseh
Norouzi, Mehdi
Ghalichi, Leila
Shamshiri, Ahmad Reza
Alavian, Seyed Moayed
Poortahmasebi, Vahdat
Jazayeri, Seyed Mohammad
Powiązania:
https://bibliotekanauki.pl/articles/2177368.pdf
Data publikacji:
2015-05-18
Wydawca:
Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:
infection control
blood-borne viruses
dentists
Health care workers
occult hepatitis B infection
HBV vaccine
Opis:
Objectives Health care workers, including dentists, are at the front line for acquiring blood-borne virus infections. This study aimed to investigate the prevalence of hepatitis B, hepatitis C and human immunodeficiency viruses among Iranian dentists. Material and Methods The survey included 1628 dental health care workers who attended the 51st annual Congress of the Iranian Dental Association. Data on the risk of blood-borne virus transmission during health care and infection control practices were gathered from self-administered questionnaires. Sera were screened serologically by enzyme-linked immunosorbent assay (ELISA). The positive samples were examined by polymerase chain reaction (PRC) followed by direct sequencing. Results Six (0.36%) and 81 (5.0%) were positive for hepatitis B surface antigen (HBsAg) and (anti-hepatitis B virus core antigen (anti-HBc), respectively. Only 1 (0.061%) was positive for anti-hepatitis C virus (anti-HCV). No case was positive for anti-human immunodeficiency virus (anti-HIV). One case was diagnosed as being occult hepatitis B virus (HBV) infection. One thousand five hundred thirty-five (94.3%) of participants had received at least 1 dose of HBV vaccine. One thousand three hundred fifty-nine (88.5%) contained hepatitis B surface antibody (anti-HBs) > 10 IU/ml, of whom 55 (4.0%) were anti-HBc positive, suggesting that they had been infected with HBV in the past. Anti-HBc positive cases had past histories of hepatitis, either their own or their spouses’. Individuals with inadequate anti-HBs levels (< 10 IU/ml) were significantly more prevalent among anti-HBc positive cases (p < 0.001). Conclusions The prevalence of blood-borne viruses among dental HCWs found in this study was lower than past reports from Iranian dentists and general population. The implementation of HBV vaccination together with improvement in infection control procedures has reduced the potential for risk infection among Iranian dentists.
Źródło:
International Journal of Occupational Medicine and Environmental Health; 2015, 28, 3; 593-602
1232-1087
1896-494X
Pojawia się w:
International Journal of Occupational Medicine and Environmental Health
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Construction and expression of indonesian hepatitis B core antigen (HBcAg) in Lactococcus lactis as potential therapeutic vaccine
Autorzy:
Anwar, R.I.
Mustopa, A.Z.
Ningrum, R.A.
Sucharsono, S.
Powiązania:
https://bibliotekanauki.pl/articles/81249.pdf
Data publikacji:
2019
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
hepatitis B virus
antigen
Lactococcus lactis
cytotoxic T
immune response
therapeutic vaccination
protein expression
patient
Indonesia
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2019, 100, 1
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Expression of hepatitis B core antigen in lettuce and tobacco for advanced plant-derived vaccine formulations
Autorzy:
Pyrski, M.
Kasprzyk, A.
Bogusiewicz, M.
Bociag, P.
Czyz, M.
Pniewski, T.
Powiązania:
https://bibliotekanauki.pl/articles/951208.pdf
Data publikacji:
2015
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
conference
hepatitis B virus
antigen expression
virus-like particle
transgenic tobacco
lettuce plant
Agrobacterium tumefaciens
immunoblot
ELISA test
Źródło:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2015, 96, 1
0860-7796
Pojawia się w:
BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Percutaneous Exposure Incidents Among Australian Hospital Staff
Autorzy:
Smith, D. R.
Leggat, P. A.
Takahashi, K.
Powiązania:
https://bibliotekanauki.pl/articles/90789.pdf
Data publikacji:
2005
Wydawca:
Centralny Instytut Ochrony Pracy
Tematy:
Percutaneous Exposure Incident
needlestick
sharps
health care workers
Australia
hospital
universal precautions
nurse
doctor
Hepatitis B
pielęgniarka przemysłowa
szpitale
wypadki przy pracy
warunki pracy
czynniki ryzyka
personel pielęgniarski
Opis:
We investigated all reported percutaneous exposure incidents (PEI) among staff from a large Australian hospital in the 3-year period, 2001–2003. There were a total of 373 PEI, of which 38.9% were needlestick injuries, 32.7% were cutaneous exposures and 28.4% sharps-related injuries. Nurses were the most commonly affected staff members, accounting for 63.5% of the total, followed by doctors (18.8%) and other staff (17.7%). Needlestick injuries were responsible for the majority of nurses’ PEI (44.7%). Sharps injuries constituted the major category for doctors (44.3%). Most needlestick injuries (67.6%) were caused by hollow-bore needles, while the majority of cutaneous exposures involved blood or serum (55.8%). Most sharps injures were caused by unknown devices (35.9%) or suture needles (34.9%). Overall, our investigation suggests that PEI is a considerable burden for health care workers in Australia. Further research is now required to determine the relationships, if any, between workers who suffer PEI and those who do not.
Źródło:
International Journal of Occupational Safety and Ergonomics; 2005, 11, 3; 323-330
1080-3548
Pojawia się w:
International Journal of Occupational Safety and Ergonomics
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Hepatic liver diseases - methods for diagnosis and medical informatics for treatment support
Autorzy:
Tsakona, A.
Paschali, K.
Tsolis, D.
Skapetis, G.
Powiązania:
https://bibliotekanauki.pl/articles/333397.pdf
Data publikacji:
2011
Wydawca:
Uniwersytet Śląski. Wydział Informatyki i Nauki o Materiałach. Instytut Informatyki. Zakład Systemów Komputerowych
Tematy:
zapalenie wątroby
wirusowe zapalenie wątroby typu A
wirusowe zapalenie wątroby typu B
marskość wątroby
informatyka medyczna
hepatitis
HAV
HBV
cirrhosis
HER
medical informatics
Opis:
Liver diseases and more specifically viral hepatitis are at the center of interest due to their global spreading, even in the most developed countries. The range of symptoms, the complications and the course of the disease have imposed the operation of liver centers at the outpatients' departments of hospitals, where the contribution of several specialized doctors the disease is diagnosed, prevented and treated. Many patients suffer from hepatitis without knowing it either because they manifest no symptoms or because the infection is not traced through the usual lab tests. This paper focuses on studying and proving how the systematic reading of the main liver diseases and the methods through which the doctor makes the diagnosis can help the study and analysis of a series of steps that have to be followed in order to treat the disease. Then, the use of a modern information system using Medical Informatics technologies is proposed so as both the task of diagnosis and the efforts to treat and overcome the problems related to the liver disease to be supported.
Źródło:
Journal of Medical Informatics & Technologies; 2011, 17; 211-218
1642-6037
Pojawia się w:
Journal of Medical Informatics & Technologies
Dostawca treści:
Biblioteka Nauki
Artykuł
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