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    Wyświetlanie 1-3 z 3
    Tytuł:
    Anticancer activity of some new series of 2-(substituted)amino-1,3-thiazole derivatives
    Autorzy:
    Bakare, Safyah B.
    Powiązania:
    https://bibliotekanauki.pl/articles/780055.pdf
    Data publikacji:
    2019
    Wydawca:
    Zachodniopomorski Uniwersytet Technologiczny w Szczecinie. Wydawnictwo Uczelniane ZUT w Szczecinie
    Tematy:
    Thiazole
    Anticancer
    Cell Cycle Analysis
    Annexin V
    FITC
    Doxorubicin
    Opis:
    A series of thiazole derivatives were synthesized and structurally elucidated by IR, 1H NMR, 13C NMR, mass and elemental analyses. The prepared compounds were screened for their cytotoxic activity against Leukemia HL-60 cell line. Compound 4b was considered as the most promising antitumor candidate among the tested compounds. Mechanism of action of compound 4b evaluated by flow cytometric assay revealed cell cycle arrest at G2/M phase and pre-G1 apoptosis. The ratio of apoptosis was also determined. Moreover, compound 4b increased the concentration of caspase 3 by 4 fold more than untreated control.
    Źródło:
    Polish Journal of Chemical Technology; 2019, 21, 3; 19-25
    1509-8117
    1899-4741
    Pojawia się w:
    Polish Journal of Chemical Technology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Fatigue Characteristics of Selected Light Metal Alloys
    Autorzy:
    Cieśla, M.
    Junak, G.
    Marek, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/357014.pdf
    Data publikacji:
    2016
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    Ti-6Al-4V titanium alloy
    2017A aluminium alloy
    AZ31 magnesium alloy
    low-cycle fatigue
    high-cycle fatigue
    fatigue life
    Opis:
    The paper addresses results of fatigue testing of light metal alloys used in the automotive as well as aerospace and aviation industries, among others. The material subject to testing comprised hot-worked rods made of the AZ31 alloy, the Ti-6Al-4V two-phase titanium alloy and the 2017A (T451) aluminium alloy. Both low- and high-cycle fatigue tests were conducted at room temperature on the cycle asymmetry ratio of R=-1. The low-cycle fatigue tests were performed using the MTS-810 machine on two levels of total strain, i.e.Δεc= 1.0% and 1.2%. The high-cycle fatigue tests, on the other hand, were performed using a machine from VEB Werkstoffprufmaschinen-Leipzig under conditions of rotary bending. Based on the results thus obtained, one could develop fatigue life characteristics of the materials examined (expressed as the number of cycles until failure of sample Nf) as well as characteristics of cyclic material strain σa=f(N) under the conditions of low-cycle fatigue testing. The Ti-6Al-4V titanium alloy was found to be characterised by the highest value of fatigue life Nf, both in lowand high-cycle tests. The lowest fatigue life, on the other hand, was established for the aluminium alloys examined. Under the high-cycle fatigue tests, the life of the 2017A aluminium and the AZ31 magnesium alloy studied was determined by the value of stress amplitude σa. With the stress exceeding 150 MPa, it was the aluminium alloy which displayed higher fatigue life, whereas the magnesium alloy proved better on lower stress.
    Źródło:
    Archives of Metallurgy and Materials; 2016, 61, 1; 271-274
    1733-3490
    Pojawia się w:
    Archives of Metallurgy and Materials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Contribution to the biology of ten vertiginid species
    Autorzy:
    Myzyk, S.
    Powiązania:
    https://bibliotekanauki.pl/articles/84447.pdf
    Data publikacji:
    2011
    Wydawca:
    Uniwersytet Mikołaja Kopernika. Wydział Biologii i Ochrony Środowiska. Stowarzyszenie Malakologów Polskich
    Tematy:
    Vertigo angustior
    Vertigo antivertigo
    Vertigo moulinsiana
    Vertigo pusilla
    Vertigo pygmaea
    Vertigo ronnebyensis
    V.ertigo substriata
    Truncatellina cylindrica
    Columella aspera
    Columella edentula
    new information
    life cycle
    snail
    land snail
    Vertiginidae
    animal reproduction
    shell variation
    vertiginid species
    habitat
    identification
    distribution
    Opis:
    Laboratory and field observations on Vertigo angustior Jeffreys, V. antivertigo (Draparnaud), V. moulinsiana (Dupuy), V. pusilla O. F. Müller, V. pygmaea (Draparnaud), V. ronnebyensis (Westerlund), V. substriata (Jeffreys), Truncatellina cylindrica (Férussac), Columella aspera Waldén and C. edentula (Draparnaud) provided new information on their life cycle. Genus Vertigo: the life span is 1–3 years, with most snails dying in the next year after hatching. The reproductive season lasts from half of May till the beginning of September; depending on the life span eggs are laid during 1–3 seasons. The number of eggs per lifetime varies widely, the maximum numbers are 55–79 in V. moulinsiana, pygmaea and ronnebyensis, 102–120 in V. angustior, pusilla and substriata and 218 in V. antivertigo. Most eggs are laid at the stage of one cell (even oocyte II), but in some the advancement of development indicates retention of 1–3 days. Hatching usually starts in the second half of June and lasts till the second half of September. Only some of the snails reach maturity in the year of hatching, usually after the reproductive season. Genus Truncatellina: in the wild the life span of most individuals is about one year, some live till the age of about two years. Eggs are laid from half of June till the end of August (in laboratory maximum 11 eggs); hatching takes place from July till the end of September. Genus Columella: in the laboratory C. aspera lays eggs from half of May till the beginning of September (maximum 5 eggs); hatching starts at half of June and continues till the end of September. C. edentula in the laboratory lays eggs at half of April, and juveniles hatch at the end of May and beginning of June.
    Źródło:
    Folia Malacologica; 2011, 19, 2
    1506-7629
    Pojawia się w:
    Folia Malacologica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-3 z 3

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