Temat: clinical epidemiology - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Underdiagnosis of childhood asthma: A comparison of survey estimates to clinical evaluation
Autorzy:: Brożek, Grzegorz M.
Farnik, Małgorzata
Lawson, Joshua
Zejda, Jan E.
Powiązania:: https://bibliotekanauki.pl/articles/2179065.pdf
Data publikacji:: 2013-12-01
Wydawca:: Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:: children
asthma
clinical epidemiology
underdiagnosis
Opis:: Objectives: Diagnostic patterns play a role in asthma prevalence estimates and could have implications for disease management. We sought to determine the extent to which questionnaire-derived estimates of childhood asthma reflect the disease's true occurrence. Materials and Methods: Children aged 6-12 years from Katowice, Poland, were recruited from a crosssectional survey (N = 1822) via primary schools. Students were categorized into three mutually exclusive groups based on survey responses: "Asthma" (previously diagnosed asthma); "Respiratory symptoms" (no previous diagnosis of asthma and one or more respiratory symptoms during last year), "No respiratory symptoms" (no previous diagnosis of asthma or respiratory symptoms). A sample of children from each group (total N = 456) completed clinical testing to determine asthma presence according to GINA recommendations. Results: Based on the survey, 5.4% of children were classified with asthma, 27.9% with respiratory symptoms, and 66.7% with no respiratory symptoms or asthma. All previously known 41 cases of asthma were confirmed. New diagnoses of asthma were made in 21 (10.9%) and 8 (3.6%) of subjects from the "Respiratory symptoms" (N = 192) and "No respiratory symptoms" (N = 223) groups, respectively. The overall prevalence of childhood asthma, incorporating the results of clinical examination, was 10.8% (95% CI: 9.4-12.2), compared to the questionnaire-derived figure of 5.4% (95% CI: 4.4-6.5%) and affected females more than males. Conclusions: Asthma prevalence was underestimated in this population possibly resulting from under-presentation or under-diagnosis. This could have potential implications for proper management and well-being of children. Questionnaire estimates of prevalence should be considered carefully in the context of regional diagnostic patterns.
Źródło:: International Journal of Occupational Medicine and Environmental Health; 2013, 26, 6; 900-909
1232-1087
1896-494X
Pojawia się w:: International Journal of Occupational Medicine and Environmental Health
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Variability of clinical characteristic of colorectal cancer patients – analysis of selected parameters
Autorzy:: Copija, Angelika
Głogowski, Łukasz
Walkiewicz, Katarzyna
Janion, Karolina
Nowakowska-Zajdel, Ewa
Powiązania:: https://bibliotekanauki.pl/articles/1035800.pdf
Data publikacji:: 2018
Wydawca:: Medical Education
Tematy:: clinical features
colorectal cancer
epidemiology
Opis:: Introduction: A steady increase of the incidence of colorectal cancer has been observed for over 30 years, particularly in well-developed countries. Colorectal cancer is one of the lifestyle-related neoplasms and depends on environmental factors. Aim: Aim of the study was to analyse selected clinical features of colorectal cancer patients. Material and methods: The study group consisted of 577 consecutive patients with colorectal cancer treated in the Department of Clinical Oncology in Bytom in 2006–2014. The patients were included into the study prospectively. The analysis of selected clinical, pathological and anthropometrical parameters was conducted. Results: The study group included 237 women and 341 men aged 26 to 86 years (mean age 64.3 ± 9.2 years). Primary tumours were mostly located in the colon and had histological grade 2. The surgical removal of the primary tumour was performed in 540 patients. 65 patients underwent preoperative radiotherapy, 201 – postoperative chemotherapy and 91 – postoperative radio-chemotherapy. 132 of patients obtained the first-line palliative chemotherapy. 88 of patients did not received oncological treatment. KRAS/RAS mutation were determined in 73 patients and the EGFR expression status in 53 patients. Conclusions: Colorectal cancer patients are a heterogeneous group with differential clinical, pathological and molecular features. 1. Therapeutic management of patients with colorectal cancer largely depends on its location, clinical and pathological stage, patients performance status and comorbidities. 2. Understanding the clinical features of patients with colorectal cancer becomes helpful in designing of screening, which take into account clinical profile of the patient, i.e. age, gender, comorbidities and anthropometric characteristics
Źródło:: OncoReview; 2018, 8, 3; 80-85
2450-6125
Pojawia się w:: OncoReview
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: The clinical and epidemiological analysis of lip carcinoma in Holy Cross District in Poland
Autorzy:: Sylwia, Postuła
Bień, Stanisław
Powiązania:: https://bibliotekanauki.pl/articles/1401759.pdf
Data publikacji:: 2016
Wydawca:: Index Copernicus International
Tematy:: lip carcinoma
epidemiology
clinical characteristics
Opis:: Objective: Lip carcinoma, as classified according to TNM system, is one of localizations of oral carcinoma. However it differs in numerous factors from other head and neck cancer. Material: 342 patients with diagnosed lip carcinoma, collected from 2001 to 2012, who in majority came from one of Poland’s region – Holy Cross District. Among them 312 were treated primarily with surgery or with surgery + Rtg. Therapy. Methods:In retrospective survey the factors of age, sex and localization of lip carcinoma were taken into analysis. Apart of that in the subgroup who underwent surgery, the local and clinical staging, histopathology and selected patho-morphological factors were also presented. Results: In the analyzed group (n=342) the sex ratio was 6 : 1 in favor of men, with average age of 69,5 years, and the most common location (93,4%) of tumor was the lower lip. The majority of treated patients (n=312) have started therapy at the lover (T1+T2) local stage (93,9%), and in 97,4% squamous cell carcinoma was finally diagnosed. Discussion: Clinico-epidemiological characteristics of presented material is similar to data found in the literature. It must be stressed out that presented results might be comparable only with the data where TNM criteria of the lip are followed.
Źródło:: Polski Przegląd Otorynolaryngologiczny; 2016, 5, 1; 47-53
2084-5308
2300-7338
Pojawia się w:: Polski Przegląd Otorynolaryngologiczny
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 4.

Tytuł:: The multicenter study result of diagnosis and treatment laryngeal carcinoma in Poland from 2001 to 2010
Autorzy:: Osuch-Wójcikiewicz, Ewa
Bruzgielewicz, Antoni
Majszyk, Daniel
Łuczaj, Jarosław
Pawlak-Osińska, Katarzyna
Stodulski, Dominik
Pomarańska, Magdalena
Kaczmarczyk, Dariusz
Leszczyńska, Małgorzata
Domka, Wojciech
Miśkiewicz-Orczyk, Katarzyna
Postuła, Sylwia
Golusiński, Paweł
Piotrowicz, Michał
Niemczyk, Kazimierz
Powiązania:: https://bibliotekanauki.pl/articles/1400552.pdf
Data publikacji:: 2016
Wydawca:: Index Copernicus International
Tematy:: laryngeal carcinoma
epidemiology
clinical characteristics
multicenter study
Opis:: Introduction: The laryngeal cancer is the most frequently diagnose malignancy in head and neck region. The highest morbidity is within male patients in the age range between 50 and 70 years. The multicenter study, coordinated by Oto-laryngology Department of Medical University of Warsaw, was designed to investigate the epidemiology of laryngeal cancer in Poland from 1980 and to analyze the evolution of diagnostic and therapeutical procedures over the years.Material and methods: There was performed retrospective analysis of the medical records of patients with laryn-geal cancer hospitalized and treated in 12 otolaryngology centers in Poland from 2001 to 2010. The Microsoft Access 2003 (SP 2) platform was used to collect the data and subsequent statistical analysis.Results: There were collected data from 4124 patients, 3682 men (89,3%) and 442 women (10,7%). The largest group consisted of patients in the age range between 50 and 60 years (41,5%) and the second large group was of those be-tween 60 and 70 years (29,6%). The history of heavy cigarettes smoking was obtained from 81,3% of patients. Re-garding the staging of laryngeal cancer, there were 1634 patients with cancer stage of I or II, including 5 patients with carcinoma in situ and 2490 patients with III or IV stage. The most frequent localization of the cancer was the glottis, followed with invasion of all three laryngeal levels and tumors occupying both the epiglottis and glottis. The major-ity of patients – 1367 (33%) – has the T3 tumor advancement. The lymph nodes metastases (N) were present in 1216 (29,5%) patients and among them the N2b and N2c advancement ( lymph node larger than 6 cm, multiple) was de-tected in 533 of patients (13%). The lymph nodes involvement occurred in majority within advanced tumors of T3 or T4a. Considering the treatment options they varied depending on the staging of laryngeal cancer. The sole surgical procedures were performed in 73,7% of patients with cancer stage of I or II and in only 28.6% of patients with the stage of III or IV. The advanced tumors were in majority treated with the combined therapy: surgery and radiotherapy. The overall survival in patients with cancer stage of I and II was 64% and 61% for those with stage III and IV.Conclusions: The rate of laryngeal cancer detection is quite high in Poland, however the period from the onset of symptoms until diagnosis should be reduced. The effectiveness of surgical treatment is definitely unsatisfactory. The project to create a multicenter permanent base for monitoring the course of diagnosis and treatment in patients with laryngeal cancer surely will verify the procedures and enable to achieve better results. Continuation of this project is a task for all otorhinolaryngologists.KEYWORDS:laryngeal carcinoma, epidemiology, clinical characteristics, multicenter study
Źródło:: Polski Przegląd Otorynolaryngologiczny; 2016, 5, 2; 1-11
2084-5308
2300-7338
Pojawia się w:: Polski Przegląd Otorynolaryngologiczny
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 5.

Tytuł:: Primary progressive multiple sclerosis in the Polish population
Pierwotnie postępująca postać stwardnienia rozsianego w populacji polskich pacjentów
Autorzy:: Brola, Waldemar
Sobolewski, Piotr
Flaga, Stanisław
Fudala, Małgorzata
Potemkowski, Andrzej
Powiązania:: https://bibliotekanauki.pl/articles/1030018.pdf
Data publikacji:: 2017
Wydawca:: Medical Communications
Tematy:: clinical course
epidemiology
multiple sclerosis
primary progressive form
Opis:: Objectives: The aim of the study was the epidemiological analysis and evaluation of selected clinical and sociodemographic factors in Polish patients with primary progressive multiple sclerosis. Methods: The study included patients from 7 provinces in central and eastern Poland registered in the Registry of Patients with Multiple Sclerosis on 31 December 2016. The incidence of various forms of the disease was compared, and clinical, demographic and social disparities between relapsing-remitting and primary progressive multiple sclerosis were analysed. Results: Of 3,199 registered patients, 2,188 persons (66.2%) had the relapsing-remitting form of multiple sclerosis, 774 (24.2%) had the secondary progressive type and 307 (9.6%) suffered from primary progressive disease. The first symptoms of primary progressive multiple sclerosis appeared almost 10 years later than in patients with the relapsing-remitting type (39.2 ± 11.4 vs. 29.8 ± 9.8). The period from the first symptoms to diagnosis was more than twice as long in patients with primary progressive multiple sclerosis (5.8 ± 3.4) as in those with relapsing-remitting disease (2.4 ± 1.6). The average degree of disability in the Expanded Disability Status Scale was similar and amounted to 3.2 ± 2.1 for relapsing-remitting and 3.6 ± 2.4 for primary progressive multiple sclerosis. The relapsing-remitting form was observed more often in women (2.4:1), and the primary progressive form appeared with equal frequency in both sexes (1:1). Disease-modifying treatment was received by 34% of patients with relapsing-remitting and in only 1.9% of patients with primary progressive multiple sclerosis. Conclusions: The primary progressive form affects approximately 10% of Polish patients with multiple sclerosis. The first symptoms appear at about 40 years of age with equal frequency in both sexes, and its diagnosis takes more than twice as much time as in the case of relapsing-remitting multiple sclerosis.
Cel: Celem badania była analiza epidemiologiczna oraz ocena wybranych czynników klinicznych i socjodemograficznych polskich pacjentów z pierwotnie postępującym stwardnieniem rozsianym. Metody: Do badania włączono pacjentów zamieszkujących 7 województw środkowej i wschodniej Polski, objętych Rejestrem Chorych ze Stwardnieniem Rozsianym w dniu 31 grudnia 2016 roku. Porównywano częstość występowania poszczególnych postaci choroby, a także analizowano różnice kliniczne, demograficzne i społeczne między postacią rzutowo-remisyjną i pierwotnie postępującą stwardnienia rozsianego. Wyniki: Spośród 3199 zarejestrowanych pacjentów postać rzutowo-remisyjną miało 2188 osób (66,2%), wtórnie postępującą – 774 (24,2%), a pierwotnie postępującą – 307 (9,6%). Pierwsze objawy postaci pierwotnie postępującej stwardnienia rozsianego pojawiały się prawie 10 lat później niż w przypadku postaci rzutowo-remisyjnej (39,2 ± 11,4 vs 29,8 ± 9,8). U chorych z postacią pierwotnie postępującą okres od pierwszych objawów do rozpoznania był ponad dwukrotnie dłuższy (5,8 ± 3,4) niż u tych z postacią rzutowo-remisyjną (2,4 ± 1,6). Średni stopień niesprawności w Rozszerzonej Skali Niewydolności Ruchowej (Expanded Disability Status Scale, EDSS) był zbliżony i wynosił 3,2 ± 2,1 dla postaci rzutowo- -remisyjnej i 3,6 ± 2,4 dla pierwotnie postępującej. Postać rzutowo-remisyjną częściej stwierdzano u kobiet (2,4:1), natomiast postać pierwotnie postępująca występowała z równą częstością u obu płci (1:1). Leczenie modyfikujące przebieg choroby otrzymywało 34% osób z postacią rzutowo-remisyjną i tylko 1,9% z pierwotnie postępującą. Wnioski: Postać pierwotnie postępująca występuje u około 10% polskich pacjentów ze stwardnieniem rozsianym, pierwsze objawy pojawiają się około 40. roku życia z jednakową częstością u obu płci, a diagnoza postaci pierwotnie postępującej zajmuje ponad dwukrotnie więcej czasu niż rozpoznanie postaci rzutowo-remisyjnej.
Źródło:: Aktualności Neurologiczne; 2017, 17, 1; 5-14
1641-9227
2451-0696
Pojawia się w:: Aktualności Neurologiczne
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 6.

Tytuł:: Clinical and epidemiological characteristics of COVID-19 during the early phase of the SARS-CoV-2 pandemic: a cross-sectional study among medical school physicians and residents employed in a regional reference teaching hospital in Northern Italy
Autorzy:: Dini, Guglielmo
Montecucco, Alfredo
Rahmani, Alborz
Barletta, Chiara
Pellegrini, Luca
Debarbieri, Nicoletta
Orsi, Andrea
Caligiuri, Patrizia
Varesano, Serena
Manca, Alessia
Vargiu, Maria Paola
Di Carlo, Pia
Massa, Emanuela
Icardi, Giancarlo
Durando, Paolo
Powiązania:: https://bibliotekanauki.pl/articles/2086076.pdf
Data publikacji:: 2021-05-27
Wydawca:: Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:: occupational health
epidemiology
healthcare workers
clinical characteristics
COVID‑19
SARS-CoV-2
Opis:: ObjectivesThe aim of the study was to evaluate the clinical presentation and burden of SARS-CoV-2 infections among medical school physicians and residents, mainly young medical doctors. The awareness of COVID‑19 clinical manifestations can improve the early detection of mild cases, possibly reducing further transmission to colleagues and patients.Material and MethodsThe study was carried out in March–May 2020, involving medical school physicians in a teaching hospital in northern Italy, with a working population of 881 medical doctors. Data collection was performed using a structured form investigating clinical and epidemiological information.ResultsOne hundred sixty-two medical doctors contacted the Occupational Health Service reporting acute respiratory symptoms or close contact exposure to a confirmed COVID‑19 case. Among the confirmed COVID‑19 cases, most were male doctors during residency, and 85% presented a mild clinical picture. Fever (70.3%) and cough (51.4%) represented the most prevalent symptoms of COVID‑19. As revealed by the univariate analysis, the prevalence of real-time reverse transcriptase-polymerase chain reaction (RT-PCR) positivity increased with age (OR = 1.08, 95% CI: 1.02–1.14, p = 0.012), working in a COVID‑19 ward (OR = 3.33, 95% CI: 1.09–10.21, p = 0.031), presenting alteration or loss of smell/taste (OR = 10.00, 95%CI: 2.80–35.69, p < 0.001) and myalgia (OR = 3.20, 95% CI: 1.00–10.26, p = 0.046), while being a resident (OR = 0.20, 95% CI: 0.05–0.80, p = 0.030) was associated with reduced odds of being infected, compared to staff physicians. Age and loss of smell/taste were the only factors independently associated with RT-PCR positivity.ConclusionsThe majority of COVID‑19 cases showed a mild clinical syndrome, ranging from absence or paucity of symptoms to common cold or influenza-like symptoms. The findings of the present study increase the accuracy of the clinical diagnosis for the prompt identification and management of suspected COVID‑19 cases, being particularly useful during resurges of the SARS-CoV-2 pandemic.
Źródło:: International Journal of Occupational Medicine and Environmental Health; 2021, 34, 2; 189-201
1232-1087
1896-494X
Pojawia się w:: International Journal of Occupational Medicine and Environmental Health
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 7.

Tytuł:: Epidemiological and clinical picture of parasitic infections in the group of children and adolescents from north-east region of Poland
Autorzy:: Żukiewicz, M.
Kaczmarski, M.
Topczewska, M.
Sidor, K.
Tomaszewska, B.
Powiązania:: https://bibliotekanauki.pl/articles/2143366.pdf
Data publikacji:: 2011
Wydawca:: Polskie Towarzystwo Parazytologiczne
Tematy:: parasitic infection
child
adolescent
Polska
human disease
epidemiology
Ascaris lumbricoides
Toxocara
Giardia lamblia
risk factor
clinical symptom
Strongyloides stercoralis
Enterobius vermicularis
ELISA test
diagnosis
Opis:: The epidemiological and clinical purview of parasite diseases is constantly evolving, mainly due to the changes in human behavior and our environment. The aim of this study was frequency analysis of certain parasite infections, risk factors and clinical symptoms in children and adolescents of north-eastern Poland. 120 children were tested due to the symptoms resembling parasite infection from December 2008 to May 2009. 90 patients (the tested group) aged from 5 months to 18 years were found to be infected with one or more than one of the following parasites: Ascaris lumbricoides, Giardia lamblia, Toxocara spp., Strongyloides stercoralis or Enterobius vermicularis. 30 children with no infections found were the control group. Parasites were found by means of microscope decantation stool tests, RIDA Quick Giardia stool test and ELISA blood test (Toxocara IgG). The patients’ parents filled out the survey concerning the probability factors of infection and the ailments that were the cause of parasitical diagnosis. High percentage of either isolated or co-invasive parasite infections was ascertained in the tested group – 75%. The prevalence of ascariasis was 55.83%, toxocariasis – 16.67%, giardiasis – 12.5%, strongyloidiasis – 5.83% and of enterobiasis – 3.33%. The statistical significance of higher dirty hands–mouth contact frequency and more frequent presence of domestic animals in the tested group than in the control group was ascertained. A highly important correlation between the infection and the occurrence of symptoms from at least 3 various systems was ascertained. The presence of habits involving dirty hands – mouth contact and having domestic animals are significant risk factors of parasite infections. The presence of symptoms from at least 3 systems should compel to parasite infection diagnosis with proper differential diagnosis.
Źródło:: Wiadomości Parazytologiczne; 2011, 57, 3; 179-187
0043-5163
Pojawia się w:: Wiadomości Parazytologiczne
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 8.

Tytuł:: Epidemiological and clinical picture of parasitic infections in the group of children and adolescents from north-east region of Poland
Autorzy:: Zukiewicz, M.
Kaczmarski, M.
Topczewska, M.
Sidor, K.
Tomaszewska, B.
Powiązania:: https://bibliotekanauki.pl/articles/837861.pdf
Data publikacji:: 2011
Wydawca:: Polskie Towarzystwo Parazytologiczne
Tematy:: parasitic infection
child
adolescent
Polska
human disease
epidemiology
Ascaris lumbricoides
Toxocara
Giardia lamblia
risk factor
clinical symptom
Strongyloides stercoralis
Enterobius vermicularis
ELISA test
diagnosis
Źródło:: Annals of Parasitology; 2011, 57, 3
0043-5163
Pojawia się w:: Annals of Parasitology
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 9.

Tytuł:: Epidemiology of non-invasive aspergillosis of the maxillary sinuses - clinical data from the Maxillofacial Surgery Clinic of the Medical University in Lublin, Poland, 2005-2014
Autorzy:: Gaweda, A.
Wojciechowicz, J.
Barszczewski, G.
Tomaszewski, T.
Powiązania:: https://bibliotekanauki.pl/articles/3258.pdf
Data publikacji:: 2014
Wydawca:: Instytut Medycyny Wsi
Tematy:: epidemiology
non-invasive aspergillosis
aspergillosis
chronic sinusitis
maxillary sinus
clinical data
Maxillofacial Surgery Clinic
Medical University of Lublin
Polska
2005-2014 period
pathology
therapy
Opis:: Fungi are organisms which occur in the human environment. One of the potential pathogenic fungi is Aspergillus which belongs to mould, and is an etiological factor of non-invasive fungal paranasal sinusitis. Objective. Epidemiological analysis of aspergillosis of the maxillary sinuses. Material and methods. Retrospective analysis of the medical histories of 41 patients treated in the Maxillofacial Surgery Department of Medical University in Lublin, Poland between 2005–2014 due to non-invasive aspergillus maxillary sinusitis. The patients’ gender, age, and etiopathogenesis of the condition with signs and symptoms, and methods of treatment were analysed. Histological examination was crucial in the final diagnosis. Results. The majority of the patients constituted women aged 29–72. The most common complaints were suborbital pain, rhinorrhoea and impaired nasal ventilation. All the patients were treated surgically, and pharmacologically with Fluconazole. Conclusion. Fungal maxillary sinusitis should be taken into account in every case of chronic maxillary sinusitis resistant to standard treatment. Women are more susceptible to Aspergillosis, and the risk factors for the disease are endodontic treatment of the maxillary teeth and fistula antro-oralis post extractionem. Surgical treatment sometimes should be complemented by pharmacological antimycotic treatment.
Źródło:: Journal of Pre-Clinical and Clinical Research; 2014, 08, 2
1898-2395
Pojawia się w:: Journal of Pre-Clinical and Clinical Research
Dostawca treści:: Biblioteka Nauki