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    Wyświetlanie 1-4 z 4
    Tytuł:
    A quantitative risk assessment of sinonasal cancer as a function of time in workers occupationally exposed to wood dust
    Autorzy:
    Soćko, Renata
    Powiązania:
    https://bibliotekanauki.pl/articles/2086482.pdf
    Data publikacji:
    2021-08-05
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    occupational exposure
    risk assessment
    wood dust
    mathematical models
    carcinogenicity
    nasal cancer
    Opis:
    ObjectivesThe aim of this study is to conduct a quantitative assessment of the risk related to occupational exposure to wood dust and the occurrence of sinonasal epithelial cancer (SNEC) by histotype, depending on the duration of exposure, using mathematical models.Material and MethodsThe relationship between the occurrence of SNEC by histotype (adenocarcinoma [AR] and tumors of other histotypes) and exposure to wood dust has been studied using the values of the odds ratios for individual periods of employment involving exposure to wood dust, and their 95% confidence intervals. The dose-response curves were constructed (more precisely, the duration of exposure-response curves). The author attempted to match the linear, quadratic or exponential models.ResultsIn all SNEC cases, there is a relationship between the duration of occupational exposure to wood dust and the relative risk of developing cancer. The estimated relative risk of developing AR after 35 years of exposure to wood dust is about 300, and the estimated risk of developing SNEC is 50, compared to non-exposed people for whom the relative risk is equal to 1. However, the relative risk of developing other types of cancer is <20, also in comparison with non-exposed people.ConclusionsThe author has identified a relationship between the duration of occupational exposure to wood dust and the relative risk of developing cancer in all SNEC cases.
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2021, 34, 4; 541-549
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The history of arsenical pesticides and health risks related to the use of Agent Blue
    Autorzy:
    Bencko, Vladimir
    Yan Li Foong, Florence
    Powiązania:
    https://bibliotekanauki.pl/articles/989807.pdf
    Data publikacji:
    2017
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    arsenicals in agriculture
    organic arsenicals use
    farmers’ health
    arsenical pesticides
    carcinogenicity
    agent blue toxicity
    Opis:
    Arsenicals in agriculture. Beginning in the 1970s, the use of arsenic compounds for such purposes as wood preservatives, began to grow. By 1980, in the USA, 70% of arsenic had been consumed for the production of wood preservatives. This practice was later stopped, due to the US Environmental Protection Agency (EPA) ban of the arsenic-and chromium-based wood preservative chromated copper arsenate. In the past, arsenical herbicides containing cacodylic acid as an active ingredient have been used extensively in the USA, from golf courses to cotton fields, and drying-out the plants before harvesting. The original commercial form of Agent Blue was among 10 toxic insecticides, fungicides and herbicides partially deregulated by the US EPA in February 2004, and specific limits on toxic residues in meat, milk, poultry and eggs, were removed. Today, however, they are no longer used as weed-killers, with one exception – monosodium methanearsonate (MSMA), a broadleaf weed herbicide for use on cotton. Severe poisonings from cacodylic acid caused headache, dizziness, vomiting, profuse and watery diarrhea, followed by dehydration, gradual fall in blood pressure, stupor, convulsions, general paralysis and possible risk of death within 3–14 days. The relatively frequent use of arsenic and its compounds in both industry and agriculture points to a wide spectrum of opportunities for human exposure. This exposure can be via inhalation of airborne arsenic, contaminated drinking water, beverages, or from food and drugs. Today, acute organic arsenical poisonings are mostly accidental. Considerable concern has developed surrounding its delayed effects, for its genotoxic and carcinogenic potential, which has been demonstrated in epidemiological studies and subsequent animal experiments. Conclusions. There is substantial epidemiological evidence for an excessive risk, mostly for skin and lung cancer, among humans exposed to organic arsenicals in occupational and environmental settings. Furthermore, the genotoxic and carcinogenic effects have only been observed at relatively high exposure rates. Current epidemiological and experimental studies are attempting to elucidate the mechanism of this action, pointing to the question whether arsenic is actually a true genotoxic, or rather an epigenetic carcinogen. Due to the complexity of its effects, both options remain plausible. Its interactions with other toxic substances still represent another important field of interest.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2017, 24, 2
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Determination and evaluation of seasonal changes of DBPs after chlorination in networks using underground water. Muş, Turkey case
    Autorzy:
    Avşar, Edip
    Sönmez, Mücahit
    Kiliç, Adile
    Powiązania:
    https://bibliotekanauki.pl/articles/2171844.pdf
    Data publikacji:
    2022
    Wydawca:
    Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
    Tematy:
    działanie rakotwórcze
    węgiel organiczny
    THM
    HAN
    chlorowanie wody
    zmiany sezonowe
    carcinogenicity
    organic carbon
    water chlorination
    seasonal changes
    Opis:
    This study aimed to determine the seasonal change of the concentrations of trihalomethanes (THMs) and one of the newly emerging byproducts haloacetonitriles (HANs), the most abundant group of some disinfection by-products (DBPs) forming as a result of chlorination of drinking water supplied from 2 different reservoirs to the city centre of Muş for disinfection purposes and called chlorinated organic halogens. The quantitative determination of these compounds, some of which may have carcinogenic properties, and the evaluation of their possible effects on public health constitute the importance of the study. The results show that although there is not sufficient chlorination in both water networks and total organic carbon (TOC) values are low in underground water, the total THMs some-times exceed the 100 μg/dm3 value applied in Turkey and pose a risk. It was observed that the total HAN values remain below the 2 μg/dm3 concentration in both networks.
    Źródło:
    Environment Protection Engineering; 2022, 48, 4; 5--19
    0324-8828
    Pojawia się w:
    Environment Protection Engineering
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Hazardous Compounds in Urban Pm in the Central Part of Upper Silesia (Poland) in Winter
    Niebezpieczne związki w miejskim pyle zawieszonym w centralnej części Górnego Śląska w zimie
    Autorzy:
    Rogula-Kozłowska, W.
    Kozielska, B.
    Klejnowski, K.
    Powiązania:
    https://bibliotekanauki.pl/articles/204935.pdf
    Data publikacji:
    2013
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    pył zawieszony
    pył PM2,5
    pył PM1
    metale ciężkie
    WWA
    wielopierścieniowe węglowodory aromatyczne
    związki rakotwórcze
    jakość powietrza
    Zabrze
    PM1
    PM2,5
    heavy metals
    PAH
    benzo(a)pyrene
    carcinogenicity
    hazardous compounds
    toxicity equivalency factor
    BEQ
    Opis:
    Thirteen fractions of ambient dust were investigated in Zabrze, a typical urban area in the central part of Upper Silesia (Poland), during a heating season. Fifteen PAH and Cr, Mn, Co, Ni, As, Se, Cd, Pb contents of each fraction were determined. The dust was sampled with use of a cascade impactor and chemically analyzed with an energy dispersive X-ray fl uorescence spectrometer (PANalytical Epsilon 5) and a gas chromatograph with a fl ame ionisation detector (Perkin Elmer Clarus 500). The concentrations of PM1 and the PM1-related PAH and elements were much higher than the ones of the coarse dust (PM2.5-10) and the substances contained in it. The concentrations of total PAH and carcinogenic PAH were very high (the concentrations of PM1-, PM2.5-, and PM10-related BaP were 16.08, 19.19, 19.32 ng m-3, respectively). The municipal emission, resulted mainly from hard coal combustion processes, appeared to be the main factor affecting the air quality in Zabrze in winter.
    Próbki trzynastu frakcji pyłu zawieszonego były pobierane w Zabrzu w okresie grzewczym (centralna część Górnego Śląska, Polska). Punkt poboru jest charakterystyczny dla obszaru miejskiego. Zbadano zawartość 15 WWA oraz Cr, Mn, Co, Ni, As, Se, Cd, Pb w każdej frakcji pyłu. Do poboru pyłu zastosowano impaktor kaskadowy, a do analizy chemicznej – spektrometr fl uorescencji rentgenowskiej z dyspersją energii (PANalytical Epsilon 5) oraz chromatograf gazowy z detektorem płomieniowo-jonizacyjnym (Perkin Elmer Clarus 500). Zarówno stężenia pyłu PM1 jak i stężenia związanych z nim WWA i pierwiastków były znacznie wyższe niż stężenia pyłu grubego (PM2.5-10) i związanych z nim substancji. Stężenia sumy WWA, a w szczególności kancerogennych związków tej grupy były bardzo wysokie (np. stężenia dla BaP związanego z PM1- i PM2.5- oraz PM10- wynosiły odpowiednio: 16.08, 19.19, 19.32 ng m-3). Na podstawie uzyskanych wyników badań dla ww. zanieczyszczeń stwierdzono, że za stan jakości powietrza w Zabrzu, w zimie, odpowiedzialna jest emisja komunalna – stacjonarne źródła spalania, głównie spalanie węgla.
    Źródło:
    Archives of Environmental Protection; 2013, 39, 1; 53-65
    2083-4772
    2083-4810
    Pojawia się w:
    Archives of Environmental Protection
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-4 z 4

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