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    Wyświetlanie 1-5 z 5
    Tytuł:
    Basal ganglia calcifications is not inconsequential in pediatric cases
    Autorzy:
    Erok, Berrin
    Tatar, Sertaç
    Uzunhan, Tuğçe Aksu
    Bezen, Diğdem
    Önder, Hakan
    Powiązania:
    https://bibliotekanauki.pl/articles/2040198.pdf
    Data publikacji:
    2021-09-30
    Wydawca:
    Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
    Tematy:
    basal ganglia calcification
    idiopathic hypoparathyroidism
    seizure
    Opis:
    Introduction. Basal ganglia calcification (BGC) in pediatric population is rare and is considered as a pathological finding. Various causes may be responsible for BGC including hypoparathyroidism, various infectious, toxicities or hereditary disorders. Aim. We aimed to present a 8 year old boy presented with generalized seizure and bilateral small amount of globus pallidum calcifications on neuroimaging studies leading to the diagnosis of idiopathic hypoparathyroidism, which is a treatable cause of seizure. Description of the case. A 8-year-old boy presented to our emergency department with generalized seizure for the first time in his life. There was no history of previous head trauma and his family history was unremarkable. Neurological examination revealed no pathological findings. Radiological imaging studies revealed only bilateral small amount of globus pallidus calcifications. He was referred to the pediatric endocrinology department for further evaluation of the hypocalcemic convulsion, where laboratory investigations revealed idiopathic hypoparathyroidism as the cause of hypocalcemic convulsion with exclusion of the other causes. Conclusion. Even a small amount of BGC in pediatric patients may be the sign of primary hypoparathyroidism and should be evaluated with serum electrolyte levels for early diagnosis and for the prevention of multisystemic complications of hypoparathyroidism.
    Źródło:
    European Journal of Clinical and Experimental Medicine; 2021, 3; 267-269
    2544-2406
    2544-1361
    Pojawia się w:
    European Journal of Clinical and Experimental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Non-ketotic hyperglycemia and diabetic striatopathy – a rare presentation with hemichorea-hemiballismus
    Autorzy:
    Erok, Berrin
    Keklikoğlu, Taha Oğuz
    Kış, Naciye
    Önder, Hakan
    Powiązania:
    https://bibliotekanauki.pl/articles/2053960.pdf
    Data publikacji:
    2022-03-30
    Wydawca:
    Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
    Tematy:
    diabetic striatopathy
    hemiballismus
    hemichorea
    hyperdense basal ganglia
    Opis:
    Introduction and aim. Non-ketotic hyperglycemia (NKHG), also known as hyperosmolar hyperglycemic state (HHS) is a serious metabolic complication of diabetes mellitus (DM).The mortality rate can be up to 20% and this is much more higher than that of diabetic ketoacidosis (DKA). It is usually precipitated by an event such as pulmonary/urinary infection, myocardial infarction (MI) or stroke. In this state of metabolic derangements, central nervous system (CNS) manifestations including altered mental status with or without focal neurological deficits are prominent clinical presentations. On the other hand, HHS may also be complicated with various other CNS events. Herein, a quite rare presentation of HHS with hemichorea ‒ hemiballismus in a 71 year old female patient with type 2 DM is presented. Description of the case. A 71-year-old female patient type 2 DM presented to our emergency department with progressive involuntary movements on the right upper and lower extremities accompanied by semiconsciousness during the last 24 hours. On neurological examination, cranial nerves and cerebellar signs were found to be normal, as the deep tendon reflexes. However, involuntary non-rhythmic writhing movements at rest were present on her right sided extremities. The fingerstick evaluation showed marked hyperglycemia (HG). The laboratory findings were characterized with high blood glucose level without obvious acidosis compatible with HHS. In urine analysis, glucosuria without significant ketonuria was detected. On head CT, subtle hyperdensity was noted in the left neostriatal regions without any mass effect or perilesional edema, compatible with left sided diabetic striatopathy (DS). Conclusion. Diabetic striatopathy is a quite rare presentation of HHS with hemichorea – hemiballismus. The characteristic computed tomograhy (CT) findings of associated striatopathy should be differentiated from vascular lesions that may also present with unilateral findings in the course of HHS and should not be overlooked in diabetic patients to recognise the ongoing HHS before the coma precedes.
    Źródło:
    European Journal of Clinical and Experimental Medicine; 2022, 1; 122-125
    2544-2406
    2544-1361
    Pojawia się w:
    European Journal of Clinical and Experimental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Do Gulf War veterans with high levels of deployment-related exposures display symptoms suggestive of Parkinson’s disease?
    Autorzy:
    Chao, Linda L.
    Powiązania:
    https://bibliotekanauki.pl/articles/2161963.pdf
    Data publikacji:
    2019-07-15
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    occupational exposure
    pesticides
    chemical exposure
    Parkinson’s disease
    basal ganglia
    Gulf War
    Opis:
    Objectives Veterans of the 1991 Gulf War (GW) were exposed to a myriad of potentially hazardous chemicals during deployment. Epidemiological data suggest a possible link between chemical exposures and Parkinson’s disease (PD); however, there have been no reliable data on the incidence or prevalence of PD among GW veterans to date. This study included the following 2 questions: 1. Do deployed GW veterans display PD-like symptoms? and 2. Is there a relationship between the occurrence and quantity of PD-like symptoms, and the levels of deployment-related exposures in GW veterans? Material and Methods Self-reports of symptoms and exposures to deployment-related chemicals were filled out by 293 GW veterans, 202 of whom had undergone 3 Tesla volumetric measurements of basal ganglia volumes. Correlation analyses were used to examine the relationship between the frequency of the veterans’ self-reported exposures to deployment-related chemicals, motor and non-motor symptoms of PD, and the total basal ganglia volumes. Results Healthy deployed GW veterans self-reported few PD-like non-motor symptoms and no motor symptoms. In contrast, GW veterans with Gulf War illness (GWI) self-reported more PD-like motor and non-motor symptoms, and more GW-related exposures. Compared to healthy deployed veterans, those with GWI also had lower total basal ganglia volumes. Conclusions Although little is known about the long-term consequences of GWI, findings from this study suggest that veterans with GWI show more symptoms as those seen in PD/prodromal PD, compared to healthy deployed GW veterans. Int J Occup Med Environ Health. 2019;32(4):503–26
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2019, 32, 4; 503-526
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Motor Control: Neural Models and Systems Theory
    Autorzy:
    Doya, K.
    Kimura, H.
    Miyamura, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/908323.pdf
    Data publikacji:
    2001
    Wydawca:
    Uniwersytet Zielonogórski. Oficyna Wydawnicza
    Tematy:
    adaptacyjny układ sterowania
    model wielokrotny
    inverse model
    adaptive control
    cerebellum
    reinforcement learning
    basal ganglia
    multiple models
    Opis:
    In this paper, we introduce several system theoretic problems brought forward by recent studies on neural models of motor control. We focus our attention on three topics: (i) the cerebellum and adaptive control, (ii) reinforcement learning and the basal ganglia, and (iii) modular control with multiple models. We discuss these subjects from both neuroscience and systems theory viewpoints with the aim of promoting interplay between the two research communities.
    Źródło:
    International Journal of Applied Mathematics and Computer Science; 2001, 11, 1; 77-104
    1641-876X
    2083-8492
    Pojawia się w:
    International Journal of Applied Mathematics and Computer Science
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Natural/sexual selection: What’s language (evolution) got to do with it?
    Autorzy:
    Progovac, Ljiljana
    Powiązania:
    https://bibliotekanauki.pl/articles/1120961.pdf
    Data publikacji:
    2019
    Wydawca:
    Uniwersytet im. Adama Mickiewicza w Poznaniu
    Tematy:
    evolution of grammar/syntax
    (sexual) selection
    decomposition of transitivity
    bro-ca’s-basal ganglia network
    (verbal) aggression
    Opis:
    By considering a specific scenario of early language evolution, here I advocate taking into account one of the most obvious players in the evolution of human language capacity: (sexual) selection. The proposal is based both on an internal reconstruction using syntactic theory, and on comparative typological evidence, directly bringing together, formal, typological, and evolutionary considerations. As one possible test case, transitivity is decomposed into evolutionary primitives of syntactic structure, revealing a common denominator and the building blocks for crosslinguistic variation in transitivity. The approximations of this early grammar, identified by such a reconstruction, while not identical constructs, are at least as good proxies of the earliest stages of grammar as one can find among tools, cave paintings, or bird song. One subtype of such “living fossils” interacts directly with biological considerations of survival, aggression, and mate choice, while others clearly distinguish themselves in fMRI experiments. The fMRI findings are consistent with the proposal that the pressures to be able to master ever more and more complex syntax were at least partly responsible for driving the selection processes which gradually increased the connectivity of the Broca’s-basal ganglia network, crucial for syntactic processing, among other important functions.
    Źródło:
    Yearbook of the Poznań Linguistic Meeting; 2019, 5, 1; 35-58
    2449-7525
    Pojawia się w:
    Yearbook of the Poznań Linguistic Meeting
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-5 z 5

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