Temat: alanine - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Taurine-EVA copolymer-paraffin rods dosimeters for EPR high-dose radiation dosimetr
Autorzy:: Maghraby, A. M.
Mansour, A.
Abdel-Fattah, A. A.
Powiązania:: https://bibliotekanauki.pl/articles/147366.pdf
Data publikacji:: 2014
Wydawca:: Instytut Chemii i Techniki Jądrowej
Tematy:: EPR
ESR
radiation dosimetry
taurine
alanine
Opis:: Taurine/EPR rods (3 × 10 mm) have been prepared by a simple technique in the laboratory where taurine powder was mixed with a molten mixture of paraffin wax and an ethylene vinyl acetate (EVA) copolymer. The binding mixture EVA/Paraffin does not present interference or noise in the EPR signal before or after irradiation. The rods show good mechanical properties for safe and multi-use handling. An EPR investigation of radiation induced radicals in taurine rods revealed that there are two types of radicals produced after exposure to gamma radiation (60Co). EPR spectra were recorded and analyzed – also the microwave power saturation and modulation amplitude were studied and optimized. Response of taurine to different radiation doses (1.5–100 kGy) was studied and found to follow a linear relationship up to 100 kGy. Radiation induced radicals in taurine persists and showed a noticeable stability over 94 days following irradiation. Uncertainities associated with the evaluation of radiation doses using taurine dosimeters were discussed and tabulated. It was found that taurine possesses good dosimetric properties using EPR spectroscopy in high doses in addition to its simple spectrum.
Źródło:: Nukleonika; 2014, 59, 1; 9-13
0029-5922
1508-5791
Pojawia się w:: Nukleonika
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Alanine dosimetry of 60 MeV proton beam - preliminary results
Autorzy:: Michalec, B.
Mierzwińska, G.
Sowa, U.
Ptaszkiewicz, M.
Nowak, T.
Swakoń, J.
Powiązania:: https://bibliotekanauki.pl/articles/146730.pdf
Data publikacji:: 2012
Wydawca:: Instytut Chemii i Techniki Jądrowej
Tematy:: alanine
dosimetry
electron paramagnetic resonance (EPR)
proton beam
Opis:: Electron paramagnetic resonance (EPR) spectrometry (X-band) was used to determine the dose absorbed in alanine detectors, of different shapes and different alanine content, irradiated with Co-60 gamma rays and in a 60 MeV proton beam. The goal of our study was to confirm applicability of alanine as a passive detector in therapeutic proton beam. In the paper dose response characteristic and relative efficiency of alanine are shown. The study confirmed that alanine detectors with a high alanine content (ca. 95%) may be a useful and convenient tool for dose measurements in proton beams, used for eye cancer treatment.
Źródło:: Nukleonika; 2012, 57, 4; 503-506
0029-5922
1508-5791
Pojawia się w:: Nukleonika
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 3.

Tytuł:: Theoretical Inversion of Amino Acids (Alanine and Aspartic Acid) by Semi-empirical Methods
Autorzy:: Mohamed, M. E.
Powiązania:: https://bibliotekanauki.pl/articles/412336.pdf
Data publikacji:: 2013
Wydawca:: Przedsiębiorstwo Wydawnictw Naukowych Darwin / Scientific Publishing House DARWIN
Tematy:: inversion
alanine
aspartic
semi-empirical methods
AM1
Opis:: The inversion reaction coordinate of free amino acids (alanine, aspartic acid) have been computationally calculated by semi-empirical methods AM1. A transition state for free alanine and aspartic acid were obtained as a three membered ring in which the α-C-H and α-C-CH3 are slightly elongated, 1.2 and 2.17 Å respectively in the alanine transition state. The activation energy of alanine is 77.52 kcal/mol in the gas phase and 76.66 kcal/mol in aqueous phase, and for aspartic acid is 54.87 kcal/mol in the gas phase and 50.86 kcal/mol in aqueous phase.
Źródło:: International Letters of Chemistry, Physics and Astronomy; 2013, 7, 1; 37-44
2299-3843
Pojawia się w:: International Letters of Chemistry, Physics and Astronomy
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 4.

Tytuł:: The Popular Ergogenic Substances in Sport and Physical Activity
Autorzy:: Świtała, Katarzyna
Powiązania:: https://bibliotekanauki.pl/articles/2192855.pdf
Data publikacji:: 2023
Wydawca:: Uniwersytet Szczeciński. Wydawnictwo Naukowe Uniwersytetu Szczecińskiego
Tematy:: β-alanine
caffeine
creatine monohydrate
creatine malate
sodium bicarbonate
Opis:: Few supplements have a scientifically proven ergogenic effects of improving exercise capacity and/or physical performance in sport. The athletes require specialised nutrition, including precisely good quality supplementation, i.e. scientifically tested. Nowadays, more and more athletes use nutritional supplementation to improve their sporting performance both at the elite and non-elite levels. In this review, ergogenic substances such as the β-alanine, caffeine, creatine monohydrate, creatine malate, sodium bicarbonate were analysed among athletes/active people from an exercise and health capacity perspective. The aim of this review is to analyse the efficacy, mechanisms of action, dosage, side effects of the selected ergogenic substances, among athletes involved in physical effort/specific sport disciplines. Furthermore, the article will show the benefits of using these supplements in terms of health as well as improvement of exercise capacity among athletes.
Źródło:: Central European Journal of Sport Sciences and Medicine; 2023, 41; 69-80
2300-9705
2353-2807
Pojawia się w:: Central European Journal of Sport Sciences and Medicine
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 5.

Tytuł:: Application of alanine dosimetry in dose assessment for ocular melanoma patients undergoing proton radiotherapy : preliminary results
Autorzy:: Mierzwińska, G.
Kłodowska, M.
Michalec, B.
Pędracka, A.
Rydygier, M.
Swakoń, J.
Waligórski, M. P. R.
Powiązania:: https://bibliotekanauki.pl/articles/146382.pdf
Data publikacji:: 2015
Wydawca:: Instytut Chemii i Techniki Jądrowej
Tematy:: alanine
EPR dosimetry
proton beam
proton radiotherapy
Quality Assurance (QA)
Opis:: Basing on alanine solid state/electron paramagnetic resonance (EPR) dosimetry, a supplementary method of cumulatively recording the therapeutic dose received by ocular cancer patients undergoing fractionated proton radiotherapy is proposed. By applying alanine dosimetry during the delivery of consecutive fractions, the dose received within each fraction can be read out by EPR spectrometry and a fi nal permanent cumulative record of the total dose delivered obtained. The dose response of the alanine detector was found to be practically independent on its position within the extended proton Bragg peak region. Dose measurements based on entrance dose recorded in proton beams individually formed for each patient are presented. The described method will be applied as a complementary Quality Assurance procedure for patients undergoing proton radiotherapy at the Institute of Nuclear Physics, Polish Academy of Sciences, Krakow, Poland (IFJ PAN).
Źródło:: Nukleonika; 2015, 60, No. 3, part 2; 609-613
0029-5922
1508-5791
Pojawia się w:: Nukleonika
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 6.

Tytuł:: Emulsion electrospinning – method to introduce proteins for biomedical applications
Autorzy:: Kurpanik, Roksana
Rapacz-Kmita, Alicja
Ścisłowska-Czarnecka, Anna
Stodolak-Zych, Ewa
Powiązania:: https://bibliotekanauki.pl/articles/2058398.pdf
Data publikacji:: 2021
Wydawca:: Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:: emulsion electrospinning
alanine
polycaprolactone
Tween 80
Triton X-100
micelle
proteiny
zastosowanie
biomedycyna
Opis:: The aim of this work was to obtain polymer fibers by the emulsion electrospinning. For this purpose, polycaprolactone (PCL) was used, which was modified before the electrospinning stage with micelles obtained by the oil-in-water (O/W) emulsion method. Micelles were obtained by combining the non-ionic surfactant Tween 80 or Triton X-100 used at different concentrations with the amino acid alanine. The obtained fibrous substrates had a typical unimodal fiber size distribution and their average size was in the range of 590-800 nm. The effectiveness of the emulsion electrospinning process was confirmed by Fourier Transform Infrared Spectroscopy - Attenuated Total Reflectance (FTIR-ATR) showing the presence of surfactants. The addition of micelles to the polymer solution significantly reduces the contact angle of nonwoven fabrics: from 120° (for PCL) to ~20-30° for surfactant-loaded nonwovens, and the micellar form allows tracking the release of alanine into the solution (UV-Vis). The combination of the core-shell- -morphology of the emulsion electrospun fibers allows comparable amino acid release times. There were no significant differences in both the amount of alanine released and the rate of its release between PCL/ Tween80/alanine and PCL/Triton X-100/alanine fibers, which were characterized by a similar fiber size.
Źródło:: Engineering of Biomaterials; 2021, 24, 162; 20--25
1429-7248
Pojawia się w:: Engineering of Biomaterials
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 7.

Tytuł:: Ontogenetic features of protein metabolism in laying hens during the rearing and egg production period
Ontogenetyczne cechy metabolizmu białek u kur nieśnych w okresie wychowu i produkcji jaj
Autorzy:: Kyryliv, B.
Powiązania:: https://bibliotekanauki.pl/articles/2606360.pdf
Data publikacji:: 2018
Wydawca:: Zachodniopomorski Uniwersytet Technologiczny w Szczecinie. Wydawnictwo Uczelniane ZUT w Szczecinie
Tematy:: laying hen
egg production
critical period
rearing
protein metabolism
amine nitrogen
alanine transaminase
aspartate transaminase
Źródło:: Acta Scientiarum Polonorum. Zootechnica; 2018, 17, 3; 17-22
1644-0714
Pojawia się w:: Acta Scientiarum Polonorum. Zootechnica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 8.

Tytuł:: Conformational properties of N-acetyl-L-alanine N',N'-dimethylamide.
Autorzy:: Siodłak, Dawid
Rzeszotarska, Barbara
Broda, Małgorzata
Powiązania:: https://bibliotekanauki.pl/articles/1043329.pdf
Data publikacji:: 2004
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: ab initio/DFT calculations
N-alkylpeptides
β-turns
alanine derivative
N',N'-dimethylamides
peptide design
Opis:: Ab initio/DFT analysis of the conformational properties of free Ac-Ala-NMe2 (N-acetyl-L-alanine-N',N'-dimethylamide) in terms of the N-H···O, N-H···N, C-H···O hydrogen bonds and Cδ+ = Oδ- dipole attractions was performed. The Ala residue combined with the C-terminal tertiary amide prefers an extended conformation and that characteristic of the (i + 1)th position of the βVIb turn. These can be easily remodelled into a structure compatible with the (i + 1)th position of the βII/βVIa turn. The residue has also the potential to adopt the conformation accommodated at both central positions of the βIII/βIII' turn or the (i + 1)th position of the βI/β'I turn.
Źródło:: Acta Biochimica Polonica; 2004, 51, 1; 137-143
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 9.

Tytuł:: Conformational properties of N',N'-dimethylamides of N-acetyldehydroalanine and N-acetyl-(Z)-dehydropheny-alanine.
Autorzy:: Siodłak, Dawid
Broda, Małgorzata
Rzeszotarska, Barbara
Kozioł, Anna
Dybała, Izabela
Powiązania:: https://bibliotekanauki.pl/articles/1044080.pdf
Data publikacji:: 2001
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: alanine and phenylalanine derivatives
N',N'-dimethylamides
X-ray crystallography
α,β-dehydroamino acids
theoretical calculations
Opis:: Conformational preferences of Ac-ΔAla-NMe2 and Ac-(Z)-ΔPhe-NMe2 were studied and compared with those of their monomethyl counterparts as well as with those of their saturated analogues. X-Ray data and energy calculations revealed a highly conservative conformation of the dehydro dimethylamides, which is located in a high-energy region of the Ramachandran map.
Źródło:: Acta Biochimica Polonica; 2001, 48, 4; 1179-1183
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 10.

Tytuł:: Influence of substitutions of Isu1 residues on binding to Jac1 protein
Autorzy:: Mozolewska, M. A.
Powiązania:: https://bibliotekanauki.pl/articles/1938619.pdf
Data publikacji:: 2016
Wydawca:: Politechnika Gdańska
Tematy:: Saccharomyces cerevisiae
Isu1-Jac1 protein complex
alanine scan
molecular dynamics
coarse-grained UNRES force field
Opis:: The iron-sulfur (Fe/S) clusters are the most ancient co-factors of proteins involved in the most essential processes in bacterial systems and yeast, such as Saccharomyces cerevisiae. The main protein involved in the Fe/S cluster transfer is the Iron sulfur cluster assembly protein 1 (Isu1), which interacts with Jac1 during one of the stages of the Fe/S cluster biogenesis cycle forming a binary complex. In this work, the interaction interface of Isu1 was investigated by selective substitutions of amino-acid residues to understand their role in binding to the Jac1 protein. An initial alanine scan was done to limit the number of possible residues subjected to the replacement and to confirm the previously obtained results. Then, MD simulations using the coarse-grained UNRES force field were run for two selected mutants: L63 V72 F94 and L63 V64 G65 D71. The analysis of the dynamics and interaction patterns of the Isu1-Jac1 complexes confirmed that the investigated residues played an important role in their binding.
Źródło:: TASK Quarterly. Scientific Bulletin of Academic Computer Centre in Gdansk; 2016, 20, 4; 417-423
1428-6394
Pojawia się w:: TASK Quarterly. Scientific Bulletin of Academic Computer Centre in Gdansk
Dostawca treści:: Biblioteka Nauki