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Wyświetlanie 1-15 z 33
Tytuł:
Alantolactone and isoalantolactone suppress maximal electroshock-induced tonic seizures in mice
Autorzy:
Luszczki, J.J.
Marzeda, E.
Kondrat-Wrobel, M.W.
Florek-Luszczki, M.
Powiązania:
https://bibliotekanauki.pl/articles/3044.pdf
Data publikacji:
2014
Wydawca:
Instytut Medycyny Wsi
Tematy:
alantolactone
isoalantolactone
electroshock-induced tonic seizure
seizure
mice
mouse
treatment
Źródło:
Journal of Pre-Clinical and Clinical Research; 2014, 08, 1
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
An uncommon manifestation of a common disease
Autorzy:
Dsilva, Giselle
Kulkarni, Vrinda
Aher, Sangeeta
Powiązania:
https://bibliotekanauki.pl/articles/972179.pdf
Data publikacji:
2017
Wydawca:
Polskie Towarzystwo Parazytologiczne
Tematy:
disseminated cysticercosis
seizure
Taenia solium
Albendazole
Opis:
Neurocysticercosis is the common parasitic disease of the central nervous system. One of the uncommon manifestations and a rare complication is its disseminated form. Human cysticercosis is caused by the spreading of the embryo of Taenia solium in the intestine via the hepatoportal system to different tissues and internal organs of the body. The organs most commonly affected are the subcutaneous tissue, skeletal muscles, lungs, brain, eyes, liver, and occasionally the heart, thyroid, and pancreas. We report a case of a 62 year old male, who has been presented, with seizures and subcutaneous nodules on both extremities. After investigation he was diagnosed as a case of disseminated cysticercosis involving brain, subcutaneous tissue, liver, muscles and pericardial fat.
Źródło:
Annals of Parasitology; 2017, 63, 4; 357-360
0043-5163
Pojawia się w:
Annals of Parasitology
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Classification of Seizure Types Using Random Forest Classifier
Autorzy:
Basri, Ashjan
Arif, Muhammad
Powiązania:
https://bibliotekanauki.pl/articles/2123290.pdf
Data publikacji:
2021
Wydawca:
Stowarzyszenie Inżynierów i Techników Mechaników Polskich
Tematy:
EEG
fast fourier transform
seizure
random forest
Opis:
Epilepsy is one of the most common mental disorders in the world, affecting 65 million people. The prevalence in Arab countries of Epilepsy is estimated at 174 per 100,000 individuals, and in Saudi Arabia is 6.54 per 1,000 individuals. Epilepsy seizures have different types, and each patient needs to have a treatment plan according to the seizure type. Hence, accurate classification of seizure type is an essential part of diagnosing and treating epileptic patients. In this paper, features based on fast Fourier transform from EEG montages are used to classify different types of seizures. Since the distribution of classes is not uniform and the dataset suffers from severe imbalance. Various algorithms are used to under-sample the majority class and over-sample the minority classes. Random forest classifier produced classification accuracy of 96% to differentiate three types of seizures from the healthy EEG reading.
Źródło:
Advances in Science and Technology. Research Journal; 2021, 15, 3; 167--178
2299-8624
Pojawia się w:
Advances in Science and Technology. Research Journal
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Basal ganglia calcifications is not inconsequential in pediatric cases
Autorzy:
Erok, Berrin
Tatar, Sertaç
Uzunhan, Tuğçe Aksu
Bezen, Diğdem
Önder, Hakan
Powiązania:
https://bibliotekanauki.pl/articles/2040198.pdf
Data publikacji:
2021-09-30
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
basal ganglia calcification
idiopathic hypoparathyroidism
seizure
Opis:
Introduction. Basal ganglia calcification (BGC) in pediatric population is rare and is considered as a pathological finding. Various causes may be responsible for BGC including hypoparathyroidism, various infectious, toxicities or hereditary disorders. Aim. We aimed to present a 8 year old boy presented with generalized seizure and bilateral small amount of globus pallidum calcifications on neuroimaging studies leading to the diagnosis of idiopathic hypoparathyroidism, which is a treatable cause of seizure. Description of the case. A 8-year-old boy presented to our emergency department with generalized seizure for the first time in his life. There was no history of previous head trauma and his family history was unremarkable. Neurological examination revealed no pathological findings. Radiological imaging studies revealed only bilateral small amount of globus pallidus calcifications. He was referred to the pediatric endocrinology department for further evaluation of the hypocalcemic convulsion, where laboratory investigations revealed idiopathic hypoparathyroidism as the cause of hypocalcemic convulsion with exclusion of the other causes. Conclusion. Even a small amount of BGC in pediatric patients may be the sign of primary hypoparathyroidism and should be evaluated with serum electrolyte levels for early diagnosis and for the prevention of multisystemic complications of hypoparathyroidism.
Źródło:
European Journal of Clinical and Experimental Medicine; 2021, 3; 267-269
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Effect of N-(p-ethoxycarbonylphenylmethyl) -p-isopropoxyphenylsuccinimide on the anticonvulsant action of four classical antiepileptic drugs in the mouse maximal electroshock-induced seizure model
Autorzy:
Łuszczki, J.J.
Marzeda, E.
Kondrat-Wrobel, M.W.
Wrobel, J.
Kocharov, S.L.
Florek-Luszczki, M.
Powiązania:
https://bibliotekanauki.pl/articles/3266.pdf
Data publikacji:
2014
Wydawca:
Instytut Medycyny Wsi
Tematy:
N-(p-ethoxycarbonylphenylmethyl) -p-isopropoxyphenylsuccinimide
anticonvulsant action
antiepileptic drug
mice
mouse
electroshock-induced seizure model
seizure
Źródło:
Journal of Pre-Clinical and Clinical Research; 2014, 08, 1
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Synthesis and study of substituted amides of some 5-membered isocyclic and heterocyclic acids as potential anticonvulsants
Autorzy:
STRUPIŃSKA, MARZANNA
JAKUBOWICZ, BARTŁOMIEJ
ROSTAFIŃSKA-SUCHAR, GRAŻYNA
PIRIANOWICZ-CHABER, ELŻBIETA
KONAROWSKA, MAGDALENA
MAZUREK, ALEKSANDER P.
Powiązania:
https://bibliotekanauki.pl/articles/895607.pdf
Data publikacji:
2018-06-30
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
Maximal electroshock seizure test
anticonvulsant activity
substituted benzylamides of isocyclic acids
substituted benzylamides of heterocyclic acids
psychomotor seizure test
Opis:
A series of substituted amides of isocyclic and heterocyclic acids have been synthesized. All obtained compounds were evaluated qualitatively for their anticonvulsant activity in the maximal electroshock seizure test (MES test) and psychomotor seizure test (6 Hz test) in mice after intraperitoneal administration. The neurological toxicity was determined in the rotorod neurotoxicity test (Tox test). Two of these compounds appeared most promising: 3-oxo-1-cyklopentanecarboxylic acid 2-fluorobenzylamide (5), 1-cyclopentenecarboxylic acid 2-(trifluoromethyl)benzylamide (8) and were tested quantitatively in MES test in mice after oral administration (o.p.) and in 6 Hz test in mice after intraperitoneal administration(i.p.). Compound (5) showed MES ED50 =82.65 mg/kg and compound (8) showed 6 Hz ED50=84.13 mg/kg.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2018, 75, 3
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Valeriana officinalis extract and 7-Nitroindozole ameliorated seizure behaviours, and 7-Nitroindozole reduced blood pressure and ECG parameters in pentylenetetrazole-kindled rats
Autorzy:
Kapucu, A.
Ustunova, S.
Akgun-Dar, K.
Powiązania:
https://bibliotekanauki.pl/articles/2087306.pdf
Data publikacji:
2020
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
Seizure
7-Nitroindazole
Valerian
PTZ kindling
Heart rate
QTc
Źródło:
Polish Journal of Veterinary Sciences; 2020, 23, 3; 349-357
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
No effect of agmatine on the protective activity of clobazam and pregabalin against maximal electroshock-induced seizures in mice
Autorzy:
Luszczki, J.J.
Jaskolska, A.
Dworzanski, W.
Kominek, M.
Mazurkiewicz, L.P.
Ossowska, G.
Powiązania:
https://bibliotekanauki.pl/articles/3584.pdf
Data publikacji:
2010
Wydawca:
Instytut Medycyny Wsi
Tematy:
agmatine
protective activity
clobazam
pregabalin
maximal electroshock-induced seizure
mice
mouse
Źródło:
Journal of Pre-Clinical and Clinical Research; 2010, 04, 1
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Diphenyl diselenide and diphenyl ditelluride increase the latency for 4-aminopyridine-induced chemical seizure and prevent death in mice
Autorzy:
Brito, Verônica
Rocha, João
Folmer, Vanderlei
Erthal, Fernando
Powiązania:
https://bibliotekanauki.pl/articles/1040644.pdf
Data publikacji:
2009
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
seizure
diphenyl diselenide
selenium
diphenyl ditelluride
4-aminopyridine
lipid peroxidation
Opis:
In this work was investigated the effect of pre-treatment with (PhSe)2 and (PhTe)2 on chemical seizure and 4-aminopyridine-induced lethality in mice. Additionally, lipid peroxidation levels of whole brain after treatment with 4-aminopyridine and effect of pre-treatment with (PhSe)2 and (PhTe)2 on these levels were investigated. Mice were pre-treated with (PhSe)2 or (PhTe)2 (50, 100, or 150 µmol/kg) 30 min before 4-aminopyridine (12 mg/kg) administration. The treatment with 4-aminopyridine caused a significant incidence of seizures (clonic, tonic) and death. Pre-treatment with (PhSe)2 and (PhTe)2 significantly increased the latency for clonic and tonic seizures, and prevented 4-aminopyridine-induced death. Significantly, the pre-treatment with (PhSe)2 or (PhTe)2 increased the latency for clonic seizures in a dose-dependent manner. Additionally, a significant increase was observed in the brain lipid peroxidation level after treatment with 4-aminopyridine, which was significantly inhibited by pre-treatment with 150 µmol/kg (PhSe)2 or (PhTe)2. These results demonstrate that (PhSe)2 and (PhTe)2 counteract the harmful effects of 4-aminopyridine. It is possible that this effect results from modulation of the redox state of N-methyl-d-aspartate receptors and/or of Ca2+ channel activity with subsequent alteration in neurotransmitter release. Importantly, this study provides evidence for anticonvulsant and antioxidant properties of (PhSe)2 and (PhTe)2, which indicates a neuroprotective activity of these compounds.
Źródło:
Acta Biochimica Polonica; 2009, 56, 1; 125-134
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Poisson Weighted Ishita Distribution: Model for Analysis of Over-Dispersed Medical Count Data
Autorzy:
Para, Bilal Ahmad
Jan, Tariq Rashid
Powiązania:
https://bibliotekanauki.pl/articles/1058917.pdf
Data publikacji:
2020-09-04
Wydawca:
Główny Urząd Statystyczny
Tematy:
compounding model
coverage probability
simulation
count data
epileptic seizure counts
Opis:
A new over-dispersed discrete probability model is introduced, by compounding the Poisson distribution with the weighted Ishita distribution. The statistical properties of the newly introduced distribution have been derived and discussed. Parameter estimation has been done with the application of the maximum likelihood method of estimation, followed by the Monte Carlo simulation procedure to examine the suitability of the ML estimators. In order to verify the applicability of the proposed distribution, a real-life set of data from the medical field has been analysed for modeling a count dataset representing epileptic seizure counts.
Źródło:
Statistics in Transition new series; 2020, 21, 3; 171-184
1234-7655
Pojawia się w:
Statistics in Transition new series
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Paroxysmal non-epileptic events vs epilepsy – what we know and where we are in medicine?
Autorzy:
Syzdoł, Bartłomiej
Ziółkiewicz, Aleksandra
Sielwanowska, Wiktoria
Żybowska, Monika
Wilczek, Natalia
Szukała, Klaudia
Chrościńska-Krawczyk, Magdalena
Powiązania:
https://bibliotekanauki.pl/articles/40495975.pdf
Data publikacji:
2024-03-30
Wydawca:
Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
Tematy:
epilepsy
non-epileptic seizure in childhood
paroxysmal non-epileptic events
Opis:
Introduction and aim. Paroxysmal non-epileptic events (PNEEs) are neurological conditions that include behavioral changes or disturbances of consciousness. The aim of the article is to compare individual paroxysmal non-epileptic events disorders, to indicate differences in their clinical picture and to discuss their differential diagnosis. Material and methods. A review of the most common non-epileptic paroxysmal events is presented based on the available literature of PubMed and Google Scholar databases from 2000 to 2023. Analysis of the literature. Depending on the age of the child, the nature and type of seizures are variable. Unfortunately, epilepsy is currently overdiagnosed, which results in the inclusion of antiepileptic drugs without the need to use them. This may be related to the immaturity of the central nervous system, malfunctioning of other organs or have a psychogenic background. In most cases, they do not require pharmacological treatment. Conclusion. Paroxysmal non-epileptic events, due to the diverse and uncharacteristic clinical picture, pose a major diagnostic challenge. Because of the current overdiagnosis of epilepsy they should always bear in mind differential diagnosis. This is important because of the differences in the treatment of these disorders.
Źródło:
European Journal of Clinical and Experimental Medicine; 2024, 22, 1; 164-171
2544-2406
2544-1361
Pojawia się w:
European Journal of Clinical and Experimental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Interaction between diuretics and tiagabine in the maximal electroshock seizure threshold test in mice
Autorzy:
Lukawski, K.
Swiderska, G.
Czuczwar, S.J.
Powiązania:
https://bibliotekanauki.pl/articles/3637.pdf
Data publikacji:
2010
Wydawca:
Instytut Medycyny Wsi
Tematy:
interaction
diuretic effect
tiagabine
maximal electroshock seizure
threshold test
mice
mouse
Źródło:
Journal of Pre-Clinical and Clinical Research; 2010, 04, 1
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
A Comparative View of Terrorist Acts and Legislative Measures Countering this Phenomenon in Albania and the United States of America
Autorzy:
Çukaj, Lirime
Powiązania:
https://bibliotekanauki.pl/articles/1036124.pdf
Data publikacji:
2013
Wydawca:
Academicus. International Scientific Journal publishing house
Tematy:
seizure
confiscation
ministry of Finance
anti-mafia law
USA patriot act
Opis:
Terrorist acts have been a worrisome phenomenon for all nations. Paradoxically, although states have been conscious about the danger of this phenomenon, there is no definition of terrorist acts so far. States have been skeptical and they have not agreed that the judgment of these criminal offences be performed by international jurisdictions, thus opting for the domestic jurisdiction. Nevertheless, states have lacked the willingness to establish joint criminal policies and find efficacious means to combat these terrorist acts. One of these efficacious means has been the seizure and confiscation of licit and illicit assets possessed by terrorist groups. This is the focus of this short study, which will be inclusive by viewing this topic under the general framework of international acts, our domestic legislation, as well as the American one. This paper aims at presenting the legislative measures taken by the Albanian state to meet international requirements. It endeavors to provide arguments why all licit and illicit assets associated with terrorist acts are seized and confiscated. Special attention is paid to the way these assets are administered. Moreover, this study tries to analyze the achievements and problems in Albania, as well as provide conclusions and recommendations.
Źródło:
Academicus International Scientific Journal; 2013, 08; 126-137
2079-3715
2309-1088
Pojawia się w:
Academicus International Scientific Journal
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Interactions of levetiracetam with ethosuximide in the mouse 6 Hz psychomotor seizure model - a type II isobolographic analysis
Autorzy:
Luszczki, J.J.
Wlaz, A.
Kondrat-Wrobel, M.W.
Pyrka, D.
Florek-Luszczki, M.
Powiązania:
https://bibliotekanauki.pl/articles/3145.pdf
Data publikacji:
2014
Wydawca:
Instytut Medycyny Wsi
Tematy:
6 Hz psychomotor seizure model
antiepileptic drug
drug interaction
ethosuximide
levetiracetam
isobolographic analysis
Opis:
The aim of the present study was to characterize the anticonvulsant effects of levetiracetam in combination with ethosuximide in the mouse 6 Hz psychomotor seizure model. Limbic (psychomotor) seizure activity was evoked in albino Swiss mice by a current (32 mA, 6 Hz, 3 s stimulus duration) delivered via ocular electrodes; type II isobolographic analysis was used to characterize the consequent anticonvulsant interactions between the drug combinations for fixed-ratios of 1:1, 1:2, 1:5 and 1:10. With type II isobolographic analysis, the combinations of levetiracetam with ethosuximide for the fixed-ratios of 1:5 and 1:10 were supra-additive (synergistic; P<0.05 and P<0.01, respectively) in terms of seizure suppression, while the combinations for the fixed-ratios of 1:1 and 1:2 were additive in the mouse 6 Hz psychomotor seizure model. The combinations of levetiracetam with ethosuximide for the fixed-ratios of 1:5 and 1:10 appear to be particularly favorable combinations exerting supra-additive interaction in the mouse 6 Hz psychomotor seizure model. Finally, it may be concluded that because of the synergistic interactions between levetiracetam and ethosuximide, the combination might be useful in clinical practice.
Źródło:
Journal of Pre-Clinical and Clinical Research; 2014, 08, 2
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Posterior reversible encephalopathy syndrome – Case report
Autorzy:
Kulczynski, M.
Kuroska, G.
Sapko, K.
Marciniec, M.
Munoz-Niklitschek, E.
Dyndor, P.
Dyndor, K.
Powiązania:
https://bibliotekanauki.pl/articles/2098209.pdf
Data publikacji:
2020
Wydawca:
Instytut Medycyny Wsi
Tematy:
oedema
posterior reversible encephalopathy syndrome
seizure
nausea
neurological deficit
ischaemia
magnetic resonance imaging
Opis:
Introduction. Posterior reversible encephalopathy syndrome (PRES) is a group of clinical disorders typically manifested by the presence of seizures, headache, impaired consciousness, nausea and focal neurological deficits. It is stated that PRES is a result of high blood pressure which leads to impaired self-regulation and hyperperfusion causing endothelial damage and vasogenic oedema or that excessive arteriolar vasoconstriction causes reduced blood flow, thus causing ischemia and cytotoxic oedema. Case Report. A 21-year-old woman was admitted to obstetrics & gynaecology department with symptoms of eclampsia. CT of the head revelaed a holohemispheric watershed pattern. MRI confirmed the presence of vasogenicoedema in the affected regions, typical for PRES. C-section was performed. Ten days after administering treatment, MRI showed complete withdrawal of the lesions. The diagnosis of PRES was based on clinical symptoms and MRI, with typical cortical and subcortical oedema without infarction.
Źródło:
Journal of Pre-Clinical and Clinical Research; 2020, 14, 4; 123-125
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Wyświetlanie 1-15 z 33

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