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Wyszukujesz frazę "Lentivirus" wg kryterium: Temat


Wyświetlanie 1-6 z 6
Tytuł:
Seroprevalence of small ruminant lentivirus infection in goats in Thailand
Autorzy:
Mongkonwattanaporn, T.
Lertwatcharasarakul, P.
Intaravichai, P.
Rukkwamsuk, T.
Powiązania:
https://bibliotekanauki.pl/articles/2087191.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
small ruminant lentivirus
ELISA
goats
prevalence
Źródło:
Polish Journal of Veterinary Sciences; 2021, 24, 2; 313-317
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The concentration of copper, zinc, manganese and selenium in the serum and liver of goats with caprine arthritis-encephalitis
Autorzy:
Milczarek, M.
Czopowicz, M.
Szara, E.
Szara, T.
Nalbert, T.
Kosieradzka, I.
Kaba, J.
Powiązania:
https://bibliotekanauki.pl/articles/2087644.pdf
Data publikacji:
2018
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
caprine arthritis-encephalitis
copper
goats
lentivirus
manganese
selenium
zinc
Źródło:
Polish Journal of Veterinary Sciences; 2018, 21, 4; 715-720
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Elevated expression of serine/threonine phosphatase type 5 correlates with malignant proliferation in human osteosarcoma
Autorzy:
Han, Kun
Gan, Zhihua
Lin, Shuchen
Hu, Haiyan
Shen, Zan
Min, Daliu
Powiązania:
https://bibliotekanauki.pl/articles/1038676.pdf
Data publikacji:
2017
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
cell proliferation
lentivirus
Osteosarcoma
PP5
siRNA
targeted therapy
Opis:
Osteosarcoma is the most common primary malignant bone tumor in adolescents and young adults. However, the involvement of serine/threonine phosphatase type 5 (PP5) in osteosarcoma remains unclear. The aim of this study was to evaluate the functional role of PP5 in osteosarcoma cells. Firstly, we found that PP5 is widely expressed in several human osteosarcoma cell lines. Then we used lentivirus-delivered siRNA to silence PP5 expression in Saos-2 and U2OS cell lines. Knockdown of endogenous PP5 expression by shRNA-expressing lentivirus significantly decreased the viability and proliferation of the osteosarcoma cells. Moreover, FACS analysis showed that knockdown of PP5 expression induced a significant arrest in the G0/G1 phase of the cell cycle, which was associated with the inhibition of cell proliferation. Therefore, knockdown of PP5 is likely to provide a novel alternative to targeted therapy of osteosarcoma and deserves further investigation.
Źródło:
Acta Biochimica Polonica; 2017, 64, 1; 11-16
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Review and future perspectives on the integration characteristics for equine lentivirus in the host genome
Autorzy:
Yu, Y.-Y.
Xu, M.-S.
Liang, H.
Wang, H.-Y.
Yu, C.-Q.
Liu, Q.
Powiązania:
https://bibliotekanauki.pl/articles/16647532.pdf
Data publikacji:
2023
Wydawca:
Polska Akademia Nauk. Czasopisma i Monografie PAN
Tematy:
lentivirus
equine infectious anemia virus
integration
long interspersed elements
Opis:
Despite over 40 years of research on the human immunodeficiency virus type 1 (HIV-1) vaccine, we still lack a considerable progress. Equine infectious anemia virus (EIAV) is a lentivirus in the Retroviridae family, akin to HIV-1 in genome structure and antigenicity. EIA is an important infectious disease in equids, characterized by anemia, persistent infection, and repeated fevers. The EIAV attenuated vaccine in China is the only lentiviral vaccine used on a large scale. Elucidating the mechanism of waning and induction of protective immunity from this attenuated vaccine strain will provide a critical theoretical basis and reference point for vaccine research, particularly in the development of lentivirus vaccines, with far-reaching scientific value and social significance. In this paper, we summarize the information related to EIAV integration site selection, particularly for the Chinese EIAV attenuated vaccine strains on the equine genome. This may improve our mechanistic understanding of EIAV virulence reduction at the host genome level. The obtained data may help elucidate the biological characteristics of EIAV, particularly the Chinese attenuated EIAV vaccine strain, and provide valuable information regarding retroviral infections, particularly lentiviral infection and associated therapeutic vectors.
Źródło:
Polish Journal of Veterinary Sciences; 2023, 26, 1; 163-172
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Antibodies to parainfluenza virus type 3 in goat population in Poland
Autorzy:
Moroz, A.
Czopowicz, M.
Mickiewicz, M.
Witkowski, L.
Szaluś-Jordanow, O.
Nalbert, T.
Klimowicz-Bodys, M.D.
Markowska-Daniel, I.
Bagnicka, E.
Kaba, J.
Powiązania:
https://bibliotekanauki.pl/articles/2087164.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
caprine arthritis-encephalitis
CAE
goats
parainfluenza
PIV-3
respiratory disease
small ruminant lentivirus
SRLV
Źródło:
Polish Journal of Veterinary Sciences; 2021, 24, 2; 235-241
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Use of HIV as a gene transfer vector
Autorzy:
Pluta, Krzysztof
Kacprzak, Magdalena
Powiązania:
https://bibliotekanauki.pl/articles/1040467.pdf
Data publikacji:
2009
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
Lentivirus
lentiviral vectors
AIDS
HIV-1 life cycle
viral-host protein interactions
gene therapy
animal transgenesis
cell engineering
Opis:
Despite the extensive research efforts over the past 25 years that have focused on HIV, there is still no cure for AIDS. However, tremendous progress in the understanding of the structure and biology of the HIV virus led to the development of safe and potent HIV-based transgene delivery vectors. These genetic vehicles are referred to as lentiviral vectors. They appear to be better suited for particular applications, such as transgene delivery into stem cells, compared to other viral- and non-viral vectors. This is because Lentivirus-based vectors can efficiently infect nondividing and slowly dividing cells. In the present review article, the current state of understanding of HIV-1 is discussed and the main characteristics that had an impact on vector design are outlined. A historical view on the vector concept is presented to facilitate discussion of recent results in vector engineering in a broader context. Subsequently, a state of the art overview concerning vector construction and vector production is given. This review also touches upon the subject of lentiviral vector safety and related topics that can be helpful in addressing this issue are discussed. Finally, examples of Lentivirus-based gene delivery systems and their applications are presented, with emphasis on animal transgenesis and human gene therapy.
Źródło:
Acta Biochimica Polonica; 2009, 56, 4; 531-595
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-6 z 6

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