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    Wyświetlanie 1-6 z 6
    Tytuł:
    Electron work function as a direct parameter for bacterial infection risk of implant surfaces
    Autorzy:
    Gołda-Cępa, M.
    Syrek, K.
    Brzychczy-Włoch, M.
    Sulka, G. D.
    Kotarba, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/284984.pdf
    Data publikacji:
    2016
    Wydawca:
    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
    Tematy:
    bacterial infections
    implants
    nanoporous materials
    Źródło:
    Engineering of Biomaterials; 2016, 19, 138; 58
    1429-7248
    Pojawia się w:
    Engineering of Biomaterials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Bacteriophages, phage endolysins and antimicrobial peptides - the possibilities for their common use to combat infections and in the design of new drugs
    Autorzy:
    Mirski, T.
    Mizak, L.
    Nakonieczna, A.
    Gryko, R.
    Powiązania:
    https://bibliotekanauki.pl/articles/2083224.pdf
    Data publikacji:
    2019
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    bacteriophages
    phage endolysins
    antimicrobial peptides
    synergy
    bacterial infections
    Opis:
    The antibiotic resistance in many pathogenic bacteria has become a major clinical problem, therefore, the necessity arises to search for new therapeutic strategies. The most promising solution lies in bacteriophages, phage endolysins and antimicrobial peptides. The aim of this study is to review the possibilities for the common use of bacteriophages, phage endolysins and antimicrobial peptides, both in the form of combined therapies and new strategies for the production of peptide drugs. Bacteriophages are viruses that specifically infect and destroy pathogenic bacteria by penetration into bacterial cells, causing metabolism disorders and, consequently, cell lysis. Phage-encoded endolysins are bacteriolytic proteins produced at the end of the phage lytic cycle that destroy elements of bacterial cell wall and enable the release of phage progeny from host cells. Antimicrobial peptides (AMPs) constitute an element of the innate immunity of living organisms and are characterized by the activity against a broad spectrum of bacteria. In the literature, there are only a few reports on the direct interaction of bacteriophages, phage endolysins and antimicrobial peptides against pathogenic bacteria. In each of them, a synergistic effect was observed, and Phage-encoded antimicrobial peptides as a specific group of AMPs have were also discussed. Phage-display technique was also reviewed in terms of its applications to produce and deliver biologically active peptides. The literature data also suggest that bacteriophages, phage endolysins and antimicrobial peptides can be used in combined therapy, thus negating many of the limitations resulting from their specificity as a single antimicrobial agent.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2019, 26, 2; 203-209
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Vaginal biocoenosis examining comparing to exfoliative cervical cytology
    Autorzy:
    Hawryluk, M.
    Ustymowicz, W.
    Hawryluk, L.
    Maciorkowska, M.
    Prycznicz, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/1918532.pdf
    Data publikacji:
    2017-11-12
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    Bacterial infections
    Candida sp
    cervical cytology
    Trichomonas vaginalis
    vaginal biocoenosis
    Opis:
    Introduction: At present, the gynaecologists have been increasingly frequently switching from vaginal biocoenosis assessment towards cervical cytology results to obtain information on the type of infection. Exfoliative cervical cytology is a screening test for dysplastic intraepithelial lesions and ectocervical cancers. One should emphasize however that one of the four parts of the new Bethesda classification specifies such inflammatory lesions as: Trichomonas vaginalis, Candida, Actinomyces, Chlamydia, cellular changes consistent with HSV infection and changes of bacterial flora. The gynaecologists however may perform vaginal biocoenosis assessment individually and diagnose its abnormalities in a relatively short timeframe.Conclusions: Lack of 100% correlation between the vaginal biocoenosis test and cytological result according to the Bethesda system means that assessment of vaginal microflora in phase-contrast microscopy should not be abandoned. Purpose: To analyse the association between lesions revealed during vaginal biocoenosis assessment in correlation to lesions described in the studies dedicated to cytological assessment of ectocervical smear. Material and methods: The study group included 1991 female patients scheduled for the follow-up cytological screening in a gynaecological office. Patients underwent gynaecological examination covering external areas, colposcopy, vaginal pH measurement, sampling for vaginal biocoenosis assessment purposes and cytological sampling. Results: It was demonstrated that diagnostic conformity for Candida sp accounted for only 17.2%, changes of bacterial flora for only 4% and – in the case of Trichomonas vaginalis - for only 3.9%. According to observations, bacterial infections and candidiases have been more frequently diagnosed during vaginal biocoenosis examining comparing to cytological screening, whereas infections with Trichomonas vaginalis have been more frequently diagnosed in cytological screening. Conclusions: Lack of 100% correlation between the vaginal biocoenosis test and cytological result according to the Bethesda system means that assessment of vaginal microflora in phase-contrast microscopy should not be abandoned.
    Źródło:
    Progress in Health Sciences; 2017, 7(2); 36-42
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Fabrication of filter membrane of organic compound to protect the upper respiratory tract from viral and bacterial infections, including SARS-CoV-2, compliant with FFP2 standard
    Autorzy:
    Brzezińska, Natalia
    Pyza, Maciej
    Kłeczek, Anna
    Kulińska, Karolina
    Gabor, Jadwiga
    Garczyk-Mundała, Żaneta
    Świnarew, Andrzej
    Powiązania:
    https://bibliotekanauki.pl/articles/24200848.pdf
    Data publikacji:
    2022
    Wydawca:
    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
    Tematy:
    face masks
    viral and bacterial infections
    betulin
    filtering membrane
    FFP2 standard
    Opis:
    Bacteria, viruses, and other pathogens in the surrounding environment are biological threat to human health and life. The development of various diseases in the world, as well as the pandemic caused by the rapid spread of the SARS-CoV-2 virus, have increased the demand for the use of upper respiratory protection devices. Out of concern for the natural environment, the aim of this work was to develop an innovative solution i.e. the FFP3 filtering membrane made of an organic compound. First, preliminary tests of the FFP2 mask were carried out to assess the chemical composition, morphological structure - fibers geometry, thickness, density, and arrangement. The FTIR analysis study was conducted to confirm that the main chemical in the mask was polypropylene (PP) and high-density polyethylene (HDPE). Optical, confocal microscopy and computer microtomography studies showed the fibers structure. They were densely arranged and their thickness was less than 1 den. The fiber structure of the FFP2 mask was also compared before and after immersing in betulin, an organic compound obtained from birch bark via the Soxhlet extraction. In addition, the assessment of microbiological activity was made on the reference strain Escherichia coli ATCC 25922, and the anti-inflammatory activity on normal human skin fibroblasts on polycarbonate with betulin. The studies showed that betulin supported the material antibacterial and anti-inflammatory properties.
    Źródło:
    Engineering of Biomaterials; 2022, 25, 166; 2--11
    1429-7248
    Pojawia się w:
    Engineering of Biomaterials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Developing a model of information transfer practice between institutions targeted at primary health care patients who are asymptomatic carriers of carbapenemase producing Enterobacteriacae
    Autorzy:
    Timler, Małgorzata
    Timler, Wojciech
    Kozłowski, Remigiusz
    Zdęba-Mozoła, Agnieszka
    Marczak, Michał
    Timler, Dariusz
    Powiązania:
    https://bibliotekanauki.pl/articles/22394055.pdf
    Data publikacji:
    2023-11-14
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    ambulatory care
    bacterial infections
    drug resistance-bacterial
    health communication
    delivery of health care
    bacteria anaerobic
    Opis:
    Background Drug-resistant bacteria are one of the main reasons of deaths worldwide. A significant group of these bacteria are carbapenemase producing Enterobacteriaceae (CPE). The goal of this study was to develop a diagnostic and therapeutic model targeted at asymptomatic carriers of CPE. Material and Methods A team of experts from different branches connected to health care, discussing the topic based on the data collected from previous research. Working sessions were dispersed between June and December 2022. The consensus has been reached via repeated discussion and literature search. Results The facility where CPE are detected is required to create an alert pathogen note and to notify sanitary-epidemiological station and National Reference Centre for Antimicrobial Susceptibility of Microorganisms – neither these institutions, nor the patient are required to notify the primary care physician. In primary care clinics, it is possible to work towards breaking the transmission of CPE by educating patients with CPE and persons who were in contact with them, and to undertake actions in order to look for patients with risk factors for CPE colonisation. In order to improve communication between individual levels of the health care system, standardised information could be introduced to the discharge note about a case of CPE, which will be electronically transmitted to the primary care facility. It might contribute to effective combating of the spread of CPE, by serving as a source of knowledge and education for patients and by checking the patient’s risk factors, which will improve the performance of tests for CPE colonisation. Conclusions The established model of good practice requires a change of legal regulations and its implementation, which will reduce the spread of CPE in health care facilities and will enable its future improvement.
    Źródło:
    Medycyna Pracy. Workers’ Health and Safety; 2023, 74, 4; 263-270
    0465-5893
    2353-1339
    Pojawia się w:
    Medycyna Pracy. Workers’ Health and Safety
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Epidemiological Trends of Antibiotic-Resistant Neisseria Gonorrhea in The EU/EEA/European Region: a Systematic Review
    Trendy epidemiologiczne dotyczące antybiotykoopornej Neisseria Gonorrhea w regionie UE/EOG/Europy: przegląd systematyczny
    Autorzy:
    Gill, Gurkeerat
    Powiązania:
    https://bibliotekanauki.pl/articles/2188100.pdf
    Data publikacji:
    2023-03-31
    Wydawca:
    Akademia Bialska Nauk Stosowanych im. Jana Pawła II w Białej Podlaskiej
    Tematy:
    Neisseria gonorrhea
    drug resistance
    bacterial infections
    epidemiology
    sexually transmitted diseases
    lekooporność
    infekcje bakteryjne
    epidemiologia
    choroby przenoszone droga płciową
    Opis:
    Neisseria gonorrhea is becoming more resistant to available antibiotic treatments. The growing antibiotic resistance of Neisseria gonorrhea in clinical isolates has been observed by different national surveillance systems around the globe and is posing a serious public health risk. The EU/EEA/European region is equally impacted by this developed antibiotic resistance in Neisseria gonorrhea isolates. Hence, this systematic review is focused to uncover the antibiotic resistance patterns of Neisseria gonorrhea across different countries in the EU/EEA/European region. The database PubMed and journal “Eurosurveillance” were used to search for the articles published between 2000-2020. Eight analytical studies that filled the selection criteria were included in the review. In the EU/EEA/European region, susceptibility and resistance of Neisseria gonorrhea toward different antibiotics varied from country to country. Neisseria gonorrhea displayed higher susceptibility toward spectinomycin and azithromycin and also displayed a high level of resistance to ciproflaxin and penicillin. With the antibiotics that are currently effective, there is a higher chance that Neisseria gonorrhea will develop gradual resistance toward those antibiotics in future too. Therefore, continuous surveillance of antibiotic-resistant Neisseria gonorrhea and health promotion awareness programs, and also investments in new effective antibiotic inventions can be helpful to tackle this issue.
    Neisseria gonorrhea staje się w coraz większym stopniu oporna na dostępne antybiotyki. Rosnącą oporność Neisseria gonorrhea na antybiotyki w izolatach klinicznych zaobserwowano za pośrednictwem różnych krajowych systemów nadzoru na całym świecie i stanowi ona poważne zagrożenie dla zdrowia publicznego. Region UE/EOG/ Europy jest w równym stopniu dotknięty rozwiniętą opornością na antybiotyki u izolatów Neisseria gonorrhea. Z tego względu niniejszy systematyczny przegląd koncentruje się na opisie wzorców oporności Neisseria gonorrhea na antybiotyki w różnych krajach UE/EOG/ Europy. Do wyszukania artykułów opublikowanych w latach 2000-2020 wykorzystano bazę danych PubMed oraz czasopismo „Eurosurveillance”. Do przeglądu włączono osiem badań analitycznych, które spełniły kryteria wyboru. W regionie UE/EOG/Europy wrażliwość i oporność Neisseria gonorrhea na różne antybiotyki różniła się w zależności od kraju. Neisseria gonorrhea wykazywała większą wrażliwość na spektynomycynę i azytromycynę, a także wykazywała wysoki poziom oporności na cyproflaksynę i penicylinę. Przy uwzględnieniu obecnie skutecznych antybiotyków istnieje większe prawdopodobieństwo, że Neisseria gonorrhea rozwinie stopniową oporność również na te antybiotyki w przyszłości. Dlatego też ciągłe monitorowanie opornych na antybiotyki bakterii Neisseria gonorrhea i zapewnienie programów uświadamiających w zakresie promocji zdrowia, a także inwestycji w nowe skuteczne rozwiązania z zakresu antybiotyków mogą być pomocne w rozwiązaniu tego problemu.
    Źródło:
    Health Problems of Civilization; 2023, 17, 1; 62-75
    2353-6942
    2354-0265
    Pojawia się w:
    Health Problems of Civilization
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
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