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    Wyświetlanie 1-11 z 11
    Tytuł:
    Utilization of the steelmaking slag by reduction with the use of the modified the chemical composition of the input material
    Zagospodarowanie żużli stalowniczych poprzez zastosowanie metody redukcji i modyfikacji składu chemicznego materiału redukowanego
    Autorzy:
    Falkus, J.
    Trębacz, L.
    Zawada, B.
    Powiązania:
    https://bibliotekanauki.pl/articles/353341.pdf
    Data publikacji:
    2010
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    żużel
    utylizacja
    redukcja
    modelowanie
    slag
    utilization
    reduction
    modeling
    Opis:
    Utilization of the steelmaking slag by reduction is the technology which seems to be today rather controversial. However it is possible to use this way of utilization in case if the economical surround will be changed. One of the possible improvement for the described method is the modifying input materials for process reduction. The thermodynamic model was developed which enable to optimize the chemical composition of the final product. The laboratory investigations confirmed a good agreement between model calculations and experimental results.
    Zastosowanie technologii redukcji żużla do utylizacji żużli stalowniczych wydaje się być dzisiaj pomysłem kontrowersyjnym. Jednakże wybór tej ścieżki utylizacji może stać się prawdopodobny w sytuacji zmiany warunków ekonomicznych w otoczeniu branży hutniczej. Jedną z metod udoskonalenia rozważanej technologii jest zastosowanie metody modyfikowania materiału wejściowego do procesu redukcji. Opracowany został model termodynamiczny, który umożliwia optymalizację składu chemicznego finalnego produktu prowadzonego procesu. Badania laboratoryjne potwierdziły dobrą zgodność obliczeń modelowych z wynikami eksperymentów.
    Źródło:
    Archives of Metallurgy and Materials; 2010, 55, 4; 1105-1112
    1733-3490
    Pojawia się w:
    Archives of Metallurgy and Materials
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Folate and homocysteine status in children with neurogenic bladder due to meningomyelocele
    Autorzy:
    Korzeniecka–Kozerska, A.
    Okurowska-Zawada, B.
    Bagińska, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/1916582.pdf
    Data publikacji:
    2014
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    folic acid
    homocysteine
    neurogenic bladder
    urodynamic investigation
    Opis:
    Introduction: Meningomyelocele (MMC) is the most severe form of spina bifida caused by both genetic and environmental components. It is well known that status of folate plays an important role in the risk of neural tube defects. High homocysteine (Hc) level may be associated with disturbed sensory and motor peripheral nerve function and is lowering after folic acid (FA) fortification. Purpose: To explore possible links of FA (folic acid) and Hc (Homocysteine) and to correlate them with renal and bladder function (based on urodynamics) as well as physical activity in patients with NB (neurogenic bladder) after MMC (myelomeningocele). Materials and methods: The investigation was conducted on two groups: group 1- 30 children with neurogenic bladder, group 2 - 20 healthy children with no abnormalities in urinary and nervous systems. The Hc concentration in urine and serum was estimated using the ELISA set and FA was measured in serum using electro-chemiluminescence method. FA/Hc ratio was calculated in all children. Results: The median serum and urine Hc were higher compared with reference group. Median FA/Hc ratio was statistically significantly lower in MMC group compared to reference group. There were no differences in serum FA between studied groups. We found statistically significant correlations between urodynamics parameters and FA and Hc. Conclusions: Hyperhomocyteinemia and hyper-homocysteinuria could be considered as factors influencing bladder function in MMC patients. Although serum FA level was in normal range in MMC patients it does not exclude disturbed folic acid status.
    Źródło:
    Progress in Health Sciences; 2014, 4, 2; 37-44
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Granulocyte colony-stimulating factor potential use in the treatment of children with cerebral palsy
    Autorzy:
    Paszko-Patej, G.
    Sienkiewicz, D.
    Okurowska-Zawada, B.
    Kułak, W.
    Powiązania:
    https://bibliotekanauki.pl/articles/1918437.pdf
    Data publikacji:
    2017
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    Granulocyte colony-stimulating factor
    neuroprotection
    studies
    cerebral palsy
    Opis:
    Granulocyte colony-stimulating factor (G-CSF) is a glycoprotein that stimulates the bone marrow to produce granulocytes and stem cells and release them into the blood. Recent studies demonstrated the presence of CSF-receptor (G-CSFR) system in the brain and spinal cord, and their roles in neuroprotection and neural tissue repair, as well as improvement in functional recovery. G-CSF exerts neuroprotective actions through the inhibition of apoptosis and inflammation, and the stimulation of neurogenesis. This review highlights recent studies on the potential use of G-CSF in cerebral palsy.
    Źródło:
    Progress in Health Sciences; 2017, 7(1); 187-192
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Effects of short moderate exercise on hematological parameters and stem cells in healthy humans
    Autorzy:
    Sochoń, K.
    Sienkiewicz, D.
    Okurowska-Zawada, B.
    Paszko-Patej, G.
    Wojtkowski, J.
    Dmitruk, E.
    Żak, J
    Kułak, W.
    Powiązania:
    https://bibliotekanauki.pl/articles/1918279.pdf
    Data publikacji:
    2016
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    Exercise
    healthy subjects
    stem cells
    Opis:
    Introduction: Exercise at various durations and intensities impact on blood and stem cells. This pilot study examined the effects of 30 minutes of treadmill walking on hematological indices and progenitor stem cells CD34+ in healthy subjects. Materials and methods: A total of 17 non-smoking, healthy students, aged 20 to 22 years participated. Hemoglobin, hematocrit, white blood cells, platelets, and stem cell CD34+ numbers were assessed before and after moderate exercise. Statistical analyses examined the relationships between CD34+ cells versus hematological indices, age, and body mass index. Results: Following exercise, significant increases were observed in leukocytes, neutrophils, eosinophils, and CD34+ cells numbers. For CD34+ cells, a fourfold increase was seen. Significant correlations between CD34+ cells, white blood cells, and neutrophils were found. Conclusion: Our results suggest that moderate exercise has a physiological impact on hematologic parameters and stem cells CD34+ in healthy subjects. Furthermore, our findings suggest that brief treadmill exercise may enhance tissue repair mechanisms so important in physiotherapy.
    Źródło:
    Progress in Health Sciences; 2016, 6(2); 184-187
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Safety and efficacy of granulocyte colony stimulating factor in a patient with tetraplegia caused by cervical hyperextension injury: a case report
    Autorzy:
    Okurowska-Zawada, B
    Kułak, W
    Sienkiewicz, D
    Paszko-Patej, G
    Dmitruk, E
    Kalinowska, A
    Wojtkowski, J
    Korzeniecka–Kozerska, A
    Powiązania:
    https://bibliotekanauki.pl/articles/1916580.pdf
    Data publikacji:
    2014
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    Cervical hyperextesniosn
    spinal cord injury
    tetraplegia
    male
    Opis:
    he authors present the case of a 17-year-old boy who suffered a cervical spinal injury as a result of the sharp bending of the head after slipping (without falling). After about 30 minutes, he began to feel tingling in the limbs and he developed tetraparesis. He went through physical rehabili-tation, psychological rehabilitation, occupational therapy, and periodic catheterization. Additionally, we introduced to him a low dose of analog granulocyte colony-stimulating factor (G-CSF). G-CSF 5 μg/kg was given subcutaneously daily for 5 days per month for 3 months, again after 6 months, and again after 10 months. The boy could sit indecently and walk with assistance. A significant increase in muscle strength in this patient with tetraplegia after 10 months of treatment may indicate beneficial effects of G-CSF in this disorder.
    Źródło:
    Progress in Health Sciences; 2014, 4, 2; 181-184
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Effects of granulocyte colony-stimulating factor therapy for osteogenesis imperfecta: a case report
    Autorzy:
    Paszko-Patej, G.
    Sienkiewicz, D.
    Kułak, W.
    Okurowska-Zawada, B.
    Wojtkowski, J.
    Kalinowska, A.
    Okulczyk, K.
    Sochoń, K.
    Dmitruk, E.
    Mirska, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/1918408.pdf
    Data publikacji:
    2017
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    Osteogenesis imperfecta
    granulocyte colony-stimulating factor
    muscle strength
    Opis:
    Introduction: Osteogenesis imperfecta (OI) is a genetic disorder of increased bone fragility and low bone mass. OI type IV. Materials and methods: We examined the safety and effectiveness of a low dose of analog granulocyte colony-stimulating factor (G-CSF) in a 15-year-old girl OI type IV. G-CSF 5 μg/kg was given subcutaneously, for 5 days/month for 3, 6 and 12 months. Laboratory tests, including blood, biochemical tests were performed, in addition to clinical examination.Results: Clinical examination revealed an increase of muscle strength in the upper and lower limbs between base line and day 6 and 12 months. We found no serious adverse events. Leukocyte levels remained below 38,000/μL. Low dose G-CSF was safe and well tolerated by the patient. Conclusions: A significant increase in muscle strength in this patient may indicate beneficial effects of G-CSF factor in this disorder. These results are inspiring and warrant further studies.
    Źródło:
    Progress in Health Sciences; 2017, 7(1); 205-208
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Effects of granulocyte colony-stimulating factor treatment in children and patients with cerebral palsy: a preliminary report
    Autorzy:
    Paszko-Patej, G.
    Kułak, W.
    Okurowska-Zawada, B.
    Sienkiewicz, D.
    Wojtkowski, J.
    Sochoń, K.
    Kalinowska, A.
    Okulczyk, K.
    Topór, E.
    Mirska, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/1918403.pdf
    Data publikacji:
    2017
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    Granulocyte colony-stimulating factor
    children
    cerebral palsy
    Opis:
    Introduction: Recent reports have revealed that neuroinflammation and apoptosis in brains affected by cerebral palsy could be therapeutic targets. Granulocyte colony-stimulating factor (G-CSF) exerts anti-inflammatory and antiapoptosis effects and stimulates the proliferation of neural stem and progenitor cells in the brain. Purpose: To assess the efficacy and safety of G-CSF treatment in children and adolescents with CP. Materials and methods: Six patients with spastic tetraplegia CP aged 3-15 years were enrolled in this study. Five patients had GMFCS (Gross Motor Function Classification System) level at V, three children had epilepsy, and three had severe mental retardation. We used the gross motor function measure-66 (GMFM-66) to assess motor function.GCSF (5μg/kg/body/day) was administered subcutaneously for five consecutive days during the four months. The parents also evaluated the physical and mental development of their children. Results: We observed improvement in motor function in patients with CP on the GMFM-66 scale. Parents reported improvement in behavior, speech development, and a decrease in spasticity in children with CP. G-CSF therapy was well-tolerated. No side effects were observed during the study. Conclusions: Our preliminary report suggests that G-CSF treatment improves motor and mental function in patients with CP. Further studies are needed to confirm these observations
    Źródło:
    Progress in Health Sciences; 2017, 7(1); 78-82
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Quality of life of children suffering from motor disabilities as evaluated by their parents
    Autorzy:
    Wojtkowski, J.
    Sienkiewicz, D.
    Okurowska-Zawada, B.
    Paszko-Patej, G.
    Konopka, A.
    Okulczyk, K.
    Średzińska, K.
    Dmitruk, E.
    Mirska, A.
    Kułak, W.
    Powiązania:
    https://bibliotekanauki.pl/articles/1918580.pdf
    Data publikacji:
    2018-01-09
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    Quality of life
    motor disability
    children
    parents
    Opis:
    Purpose: We assessed the quality of life of children with motor disabilities in comparison with healthy children, as evaluated by their parents, using the CHQ-PF28 questionnaire (Child Health Questionnaire—Parent Form). Materials and methods: In a prospective study, we evaluated the quality of life of 105 children with motor disabilities. Results: Our research showed lower quality of life in the group of children with motor disabilities compared with controls, both in terms of physical and psychosocial health. Significant correlations between independent walking and physical functioning, general behavior, and mental health of children suffering from motor disabilities were found. According to the average indices of quality of life of children suffering from motor disabilities, depending on sex, the greatest differences occurred in behavior and change of health status, while the smallest differences in self-esteem and parental involvement, compared with controls. In the case of healthy children, the largest differences appeared in the perception of pain, behavior, and self-esteem; whereas, the smallest variations occurred in the change of health status and physical activity. Conclusion: Children suffering from motor disabilities demonstrate lower quality of life compared with healthy children.
    Źródło:
    Progress in Health Sciences; 2017, 7(2); 60-66
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Granulocyte colony-stimulating factor therapy for facioscapulohumeral dystrophy: a case report
    Autorzy:
    Sienkiewicz, D.
    Kułak, W.
    Okurowska-Zawada, B.
    Paszko-Patej, G.
    Wojtkowski, J.
    Dmitruk, E.
    Okulczyk, K.
    Sochoń, K.
    Kalinowska, A.
    Żak, J.
    Pogorzelski, R.
    Powiązania:
    https://bibliotekanauki.pl/articles/1918329.pdf
    Data publikacji:
    2016
    Wydawca:
    Uniwersytet Medyczny w Białymstoku
    Tematy:
    Facioscapulohumeral dystrophy
    granulocyte colony-stimulating factor
    muscle strength
    Opis:
    We examined the safety and effectiveness of a low dose of analog granulocyte-colony stimulating factor in a 15-year-old boy with facioscapulohumeral dystrophy. The onset of disease was noted at 12 years of age. The physical examination noted general muscle atrophy more pronounced at left side of the body. He was able to walk 300 meters within 6 minute walk test. Granulocyte colony-stimulating factor 5 μg/kg was given subcutaneously daily for 5 days/month for 1, 2, 3, 6 and 12 months. Clinical examination, laboratory tests including blood, biochemical tests, and CD34+ cells were performed. A significant increase of muscle strength in the lower and upper limbs between baseline, and after 3 months of treatment, after 6, and after 12 months was found. He was able to walk 480 meters within 6 minutes after 12 months. Electromyography demonstrated increase of amplitude in the examined in upper and lower limbs after six months compared to baseline. Leukocyte levels remained below 25000/μL. CD34+ increased significantly at day 5 of granulocyte colony-stimulating factor admini-stration. It was safe and well tolerated by the patient. A significant increase in muscle strength in this patient with facioscapulohumeral dystrophy after 3 months of treatment, after 6, and after 12 months since the first treatment course was completed may indicate beneficial effects of granulocyte colony-stimulating factor in this disorder.
    Źródło:
    Progress in Health Sciences; 2016, 6(2); 175-177
    2083-1617
    Pojawia się w:
    Progress in Health Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Measurement of tool flank wear with the use of white light interferometer
    Pomiar zużycia ostrza skrawającego interferometrem światła białego
    Autorzy:
    Zawada-Tomkiewicz, A.
    Storch, B.
    Powiązania:
    https://bibliotekanauki.pl/articles/152482.pdf
    Data publikacji:
    2010
    Wydawca:
    Stowarzyszenie Inżynierów i Techników Mechaników Polskich
    Tematy:
    geometria narzędzia
    zużycie na powierzchni przyłożenia
    chropowatość na zaokrągleniu krawędzi skrawającej
    tool geometry
    flank wear
    roughness of the cutting edge rounding
    Opis:
    Tool geometry is one of the key factors influencing the quality of the cutting process. Usually the geometry is described for a new tool and the changes in it during cutting are explained with the use of tool wear indexes. They are quite easy to measure when the wear is significant. However, for the finishing processes the location of tool edge and the roughness of the tool edge are the most important factors, which are difficult to measure mainly because of a very developed surface of wear land with a number of difficult to measure points. In the paper, the Talysurf CCI 6000 was used to measure tool cutting wedge geometry, flank wear and roughness of the cutting edge. Measurement of tool irregularities with the use of CCI 6000 was rapid but its application was limited for measurement tool geometry in a state of wear.
    Geometria narzędzia jest kluczowym czynnikiem wpływającym na jakość procesu skrawania. Geometria podawana jest dla narzędzia nowego, natomiast zmiany na ostrzu podczas jego pracy opisywane są za pomocą wskaźników zużycia ostrza zdefiniowanych w normie ISO 3685. Wyznaczenie wartości wskaźników zużycia ostrza nie nastręcza wielu problemów, gdy wielkość ta dotyczy zużycia na granicy trwałości narzędzia [1-5]. Natomiast dla obróbki wykończeniowej decydującym o jakości procesu jest położenie krawędzi skrawającej (wymiar geometryczny przedmiotu) oraz chropowatość krawędzi skrawającej (mikrochropowatość powierzchni obrobionej) [6-9]. Charakterystyki te są trudne do zmierzenia ze względu na rozwiniętą powierzchnię zużycia ostrza oraz występujące mikropowierzchnie o znacznym nachyleniu. W artykule zaprezentowano pomiar geometrii narzędzia, zużycia na powierzchni przyłożenia oraz chropowatości powierzchni obrobionej przy zastosowaniu Talysurf CCI 6000 [10]. Pomiar przy użyciu CCI 6000 okazał się niezwykle szybki i dokładny. Ze względu na ograniczony zakres pomiaru wielkości, zarówno w pionie jak i w poziomie, dominującym czynnikiem określającym możliwości pomiarowe okazało się precyzyjne ustawianie ostrza podczas pomiaru.
    Źródło:
    Pomiary Automatyka Kontrola; 2010, R. 56, nr 8, 8; 950-953
    0032-4140
    Pojawia się w:
    Pomiary Automatyka Kontrola
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Spin trapping studies of essential oils in lipid systems
    Autorzy:
    Makarova, K.
    Drązikowska, K.
    Suska, B.
    Zawada, K.
    Wawer, I.
    Powiązania:
    https://bibliotekanauki.pl/articles/147786.pdf
    Data publikacji:
    2015
    Wydawca:
    Instytut Chemii i Techniki Jądrowej
    Tematy:
    spin trapping ESR
    essential oils
    DFT calculations
    lipids
    Opis:
    In the present work, we report the results of a spin trapping ESR study of four essential oils widely used for skin care products such as creams and bath salts. The studied essential oils are Rosmarini aetheroleum (rosemary), Menthae piperitae aetheroleum (mint), Lavandulae aetheroleum (lavender), and Thymi aetheroleum (thyme). Fenton reaction in the presence of ethanol was used to generate free radicals. The N-tert- -butyl-α-phenylnitrone (PBN) was used as a spin trap. In the Fenton reaction, the rosemary oil had the lowest effect on radical adduct formation as compared to the reference Fenton system. Since essential oils are known to be lipid soluble, we also conducted studies of essential oils in Fenton reaction in the presence of lipids. Two model lipids were used, namely 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) and 1,2-dipalmitoyl-sn- -glycero-3-phosphocholine (DPPC). The obtained results suggested that in the presence of DOPC lipids, the •OH and PBN/•CHCH3(OH) radicals are formed in both phases, that is, water and lipids, and all the studied essential oils affected the Fenton reaction in a similar way. Whereas, in the DPPC system, the additional type of PBN/X (aN = 16.1 G, aH = 2.9 G) radical adduct was generated. DFT calculations of hyperfi ne splittings were performed at B3LYP/6-311+G(d,p)/EPR-II level of theory for the set of c-centered PBN adducts in order to identify PBN/X radical.
    Źródło:
    Nukleonika; 2015, 60, No. 3, part 1; 461-468
    0029-5922
    1508-5791
    Pojawia się w:
    Nukleonika
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-11 z 11

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