Autor: Wawrzyniak, Dariusz - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Searching for anti-glioma activity. Ribonucleoside analogues with modifications in nucleobase and sugar moieties
Autorzy:: Framski, Grzegorz
Wawrzyniak, Dariusz
Jahnz-Wechmann, Zofia
Szymanska-Michalak, Agnieszka
Kraszewski, Adam
Barciszewski, Jan
Boryski, Jerzy
Stawinski, Jacek
Powiązania:: https://bibliotekanauki.pl/articles/1038738.pdf
Data publikacji:: 2016
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: ribonucleoside analogues
anti-glioblastoma activity
anticancer ribonucleotides
Opis:: Several ribonucleoside analogues with modifications in the nucleobase and sugar moiety have been screened for anti-glioma activity in the T98G glioma cell line using cervical (HeLa) cell line as reference human malignant cells, and lung fibroblast (MCR-5) cell line as non-cancerous reference cells. Among the investigated compounds, ribonucleosides containing 6-chloropurine (3), 7-guanine (5) and a pyrrolopyrimidine (18) as nucleobases, show promising anti-glioma activity with good selectivity indices, and can be considered as lead structures for further anti-cancer studies.
Źródło:: Acta Biochimica Polonica; 2016, 63, 4; 765-771
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Electronic nose with polymer-composite sensors for monitoring fungal deterioration of stored rapeseed
Autorzy:: Gancarz, Marek
Wawrzyniak, Jolanta
Gawrysiak-Witulska, Marzena
Wiącek, Dariusz
Nawrocka, Agnieszka
Rusinek, Robert
Powiązania:: https://bibliotekanauki.pl/articles/973040.pdf
Data publikacji:: 2017
Wydawca:: Polska Akademia Nauk. Instytut Agrofizyki PAN
Tematy:: principal component analysis
e-nose
rapeseed
ergosterol
colony forming units
volatile organic compounds
Opis:: Investigations were performed to examine the possibility of using an electronic nose to monitor development of fungal microflora during the first eighteen days of rapeseed storage. The Cyranose 320 device manufactured by Sensigent was used to analyse volatile organic compounds. Each sample of infected material was divided into three parts and the degree of spoilage was measured in three ways: analysis of colony forming units, determination of ergosterol content, and measurement of volatile organic compounds with the e-nose. Principal component analysis was performed on the generated patterns of signals and six groups of different spoilage levels were isolated. An analysis of sensorgrams for a few sensors with a strong signal for each group of rapeseed spoilage was performed. The ratio of the association time to the steady state was calculated. This ratio was different for the low level and the highest level of ergosterol and colony forming units. The results have shown that the e-nose can be a useful tool for quick estimation of the degree of rapeseed spoilage.
Źródło:: International Agrophysics; 2017, 31, 3
0236-8722
Pojawia się w:: International Agrophysics
Dostawca treści:: Biblioteka Nauki

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