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    Wyświetlanie 1-2 z 2
    Tytuł:
    Effect of substrate stiffness on differentiation of umbilical cord stem cells
    Autorzy:
    Witkowska-Zimny, Małgorzata
    Walenko, Katarzyna
    Wałkiewicz, Anna
    Pojda, Zygmunt
    Przybylski, Jacek
    Lewandowska-Szumieł, Małgorzata
    Powiązania:
    https://bibliotekanauki.pl/articles/1039745.pdf
    Data publikacji:
    2012
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    substrate stiffness
    osteogenic differentiation
    umbilical cord mesenchymal stromal/stem cells
    Opis:
    Tissue formation and maintenance is regulated by various factors, including biological, physiological and physical signals transmitted between cells as well as originating from cell-substrate interactions. In our study, the osteogenic potential of mesenchymal stromal/stem cells isolated from umbilical cord Wharton's jelly (UC-MSCs) was investigated in relation to the substrate rigidity on polyacrylamide hydrogel (PAAM). Osteogenic differentiation of UC-MSCs was enhanced on stiff substrate compared to soft substrates, illustrating that the mechanical environment can play a role in differentiation of this type of cells. These results show that substrate stiffness can regulate UC-MSCs differentiation, and hence may have significant implications for design of biomaterials with appropriate mechanical properties for regenerative medicine.
    Źródło:
    Acta Biochimica Polonica; 2012, 59, 2; 261-264
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Adaptive and maladaptive perfectionism, and professional burnout among medical laboratory scientists
    Autorzy:
    Robakowska, Marlena
    Tyrańska-Fobke, Anna
    Walkiewicz, Maciej
    Tartas, Małgorzata
    Powiązania:
    https://bibliotekanauki.pl/articles/2162449.pdf
    Data publikacji:
    2018-05-22
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    burnout
    adaptive perfectionism
    maladaptive perfectionism
    laboratory scientists
    disengagement
    exhaustion
    Opis:
    Background The goal of this paper is to verify the correlations between adaptive and maladaptive perfectionism and the selected demographic and job characteristics vs. professional burnout among medical laboratory scientists in Poland. Material and Methods The study group consisted of 166 laboratory scientists. The Polish Adaptive and Maladaptive Perfectionism Questionnaire (Szczucka) was used for testing perfectionism. The Oldenburg Burnout Inventory was used for examining burnout syndrome. Results Adaptive perfectionism was positively and maladaptive perfectionism was negatively correlated with both aspects of professional burnout: the disengagement from work and exhaustion. What is more, maladaptive perfectionism was correlated negatively with age and work experience. People in relationships have a higher level of disengagement and a higher level of exhaustion than single ones. The results of hierarchical regression analyses have revealed, after having controlled selected demographic and job factors, that a significant predictor of disengagement is the high level of adaptive perfectionism and low level of maladaptive perfectionism. In addition, a significant predictor of high level of exhaustion is the low level of maladaptive perfectionism. Conclusions Professional burnout among medical laboratory scientists is of a specific nature. The “healthier” perfectionism they reveal, the higher level of burnout they present. In this profession, lower risk of burnout is represented by those who are characterized by the lack of confidence in the quality of their actions and a negative reaction to their own imperfections associated with imposed social obligation to be perfect. The individuals pursuing their internal high standards experience burnout faster. Med Pr 2018;69(3):253–260
    Źródło:
    Medycyna Pracy; 2018, 69, 3; 253-260
    0465-5893
    2353-1339
    Pojawia się w:
    Medycyna Pracy
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-2 z 2

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