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Wyświetlanie 1-4 z 4
Tytuł:
Decreasing the Retirement Age in the View of Dynamically Ageing Population in Poland
Obniżenie wieku emerytalnego wobec dynamicznie starzejącej się populacji w Polsce
Autorzy:
Iwański, Rafał
Tomczak, Łukasz
Lipska-Sondecka, Agnieszka
Powiązania:
https://bibliotekanauki.pl/articles/1857828.pdf
Data publikacji:
2021-03-31
Wydawca:
Wydawnictwo Adam Marszałek
Tematy:
pension system
social insurance
retirement security
system emerytalny
ubezpieczenie społeczne
ubezpieczenie emerytalne
Opis:
The aim of the article is to present expectations and attitudes of Polish society towards the retirement age. The problem is crucial due to dynamic ageing of population. The research was conducted on a national research sample with calculations based on stratified quota sampling. The research was conducted in 2019 on a sample of n = 2088 respondents. Despite the ageing population, the majority of respondents believe that the age entitling to retirement benefits should not be higher than 60 years for women and 65 for men. Residents of larger cities and respondents with higher earnings supported a higher retirement age. Respondents stated that the most significant factor influencing the amount of retirement benefits is job seniority and the amount of contributions to retirement pension schemes, not the condition of Polish and world economy. The presented results are extremely important for current and future rulers due to the design of changes in the scope of retirement benefits.
Celem artykułu jest przedstawienie oczekiwań i postaw społeczeństwa polskiego wobec wieku emerytalnego. Problem jest istotny ze względu na dynamiczne starzenie się populacji. Badania przeprowadzono na ogólnopolskiej próbie badawczej, opartej o dobór kwotowo-warstwowy. Badanie przeprowadzono w 2019 roku na próbie n = 2088 respondentów. Mimo starzenia się społeczeństwa większość respondentów uznała, że wiek uprawniający do emerytury nie powinien przekraczać 60 lat dla kobiet i 65 lat dla mężczyzn. Mieszkańcy większych miast i respondenci o wyższych zarobkach opowiadali się za wyższym wiekiem emerytalnym. Respondenci wskazywali, że najważniejszym czynnikiem wpływającym na wysokość świadczeń emerytalnych jest staż pracy i wysokość składek na emerytury, a nie stan gospodarki polskiej i światowej. Przedstawione wyniki są niezwykle istotne dla obecnych i przyszłych rządzących ze względu na projektowanie zmian w zakresie świadczeń emerytalnych.
Źródło:
Athenaeum. Polskie Studia Politologiczne; 2021, 71; 77-88
1505-2192
Pojawia się w:
Athenaeum. Polskie Studia Politologiczne
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Myeloid sarcoma associated with blast crisis in chronic myelogenous leukemia - case report
Autorzy:
Szymczyk, Agnieszka
Podhorecka, Monika
Tomczak, Waldemar
Szumiło, Justyna
Hus, Marek
Powiązania:
https://bibliotekanauki.pl/articles/972387.pdf
Data publikacji:
2016
Wydawca:
Instytut Medycyny Wsi
Tematy:
myeloid sarcoma
chronic myelogenous leukemia
blast crisis
Opis:
Introduction. Myeloid sarcoma (MS) is a rare extramedullary tumour which may precede or occur concomitantly with bone marrow involvement in acute myeloid leukemia, myelodysplastic syndrome, or blast crisis in chronic myeloproliferative disorder. Myeloid sarcoma is most commonly found in lymph nodes, skin, subcutaneous tissue and gums, while it is less common in bones, the retroperitoneal space and eye socket. Case Report. The case is reported of a 65-year-old woman with chronic myelogenous leukemia treated for about 20 years with hydroxyurea, 6-mercaptopurine and tyrosine-kinase inhibitors. During the treatment, the general condition of the patient progressively deteriorated, lymphadenopathy and splenomegaly worsened, and blast crisis was diagnosed. After the first cycle of induction chemotherapy, the patient’s lymph nodes were swollen and painful. One of the lymph nodes was subjected to histopathology, on the basis of which a diagnosis of MS was made. As the patient showed no response to the treatment, palliative care was initiated. Three months after the diagnosis of MS, the disease progressed. The patient died of infectious complications. Conclusions: A diagnosis of MS, which is considered an adverse prognostic factor, significantly reduces the chances of remission and overall survival in patients with acute myelogenous leukemia or blast crisis inchronic myeloproliferative disorders. It seems that early confirmation of the diagnosis and initiation of the treatment adjusted to the patient’s clinical condition may improve the prognosis and increase the response rates.
Źródło:
Journal of Pre-Clinical and Clinical Research; 2016, 10, 2; 136-139
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
STABILITY STUDIES OF CEFTIOFUR SODIUM IN AQUEOUS SOLUTIONS AND IN THE SOLID PHASE
Autorzy:
Dołhań, Agnieszka
Sobczak, Agnieszka
Muszalska, Izabela
Medenecka, Beata
Garbacki, Piotr
Tomczak, Szymon
Jelińska, Anna
Powiązania:
https://bibliotekanauki.pl/articles/895368.pdf
Data publikacji:
2018-12-31
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
stability
kinetic parameters
thermodynamic parameters
solid phase
Opis:
Ceftiofur sodium (CFT), a third-generation cephalosporin for parenteral use, is commonly used in veterinary medicine against aerobic Gram-positive and Gram-negative bacteria as well as certain anaerobes. Its broad spectrum of activity and resistance to beta-lactamases result from the presence of methoxyimino and aminothiazole moieties at C-7 in the cephalosporin structure. The aim of this study was a comprehensive evaluation of the stability of CFT in the solid phase and in aqueous solutions. A fast and sensitive HPLC isocratic method was used for the determination of CFT degradation in the solid phase and in aqueous solutions. CFT degradation occurred according to a first-order reaction depending on the substrate concentration. The kinetic and thermodynamic parameters of CFT degradation in the solid phase were calculated. General acid-base hydrolysis of CFT was not observed in the solutions of hydrochloric acid, sodium hydroxide, phosphate (pH 5.84 – 7.25), acetate (pH 3.65 – 5.48) and borate (pH 7.49 – 10.07) buffers. CFT was the most stable in the pH range 2 – 6. The susceptibility of CFT to degradation under the influence of stress factors (pH, temperature, buffer components concentration, relative air humidity) should be considered in terms of storage conditions and the preparation of the product for administration.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2018, 75, 6; 1279-1286
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Mitochondria-associated satellite I RNA binds to hnRNP K protein
Autorzy:
Klimek-Tomczak, Karolina
Mikula, Michał
Dzwonek, Artur
Paziewska, Agnieszka
Wyrwicz, Lucjan
Hennig, Ewa
Ostrowski, Jerzy
Powiązania:
https://bibliotekanauki.pl/articles/1041284.pdf
Data publikacji:
2006
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
hnRNP K protein
SAGE
mitochondria
satellite I RNA
Opis:
hnRNP K protein, which localizes to the nucleus, cytoplasm and mitochondria, is involved in the various cellular processes that compose gene expression. We used a SAGE-based assay to profile RNAs associated with hnRNP K protein in rat mitochondria. RNA was isolated from mitoplasts obtained from highly purified and RNase-treated mitochondria. Total RNA and RNA associated with hnRNP K protein were then used as input material for generating two SAGE libraries. Mitochondrion-derived tags isolated from the total mitoplast RNA library represented 86.3%, while those isolated from the library constructed from RNA associated with hnRNP K protein represented only 28.2% of selected tags. Thus, an unexpected number of nuclear-encoded RNAs were purified from mitochondria. Many of these transcripts were co-purified with hnRNP K protein, and high levels of nuclear-encoded RNAs co-immunoprecipitating with K protein corresponded to elevated hnRNP K protein levels of the organelle. The most abundant RNAs that were co-purified with hnRNP K protein represented transcripts originating from satellite I DNA. While satellite I RNA levels were higher in the nucleus and cytoplasm than in mitochondria, the most abundant binding of satellite I transcripts to hnRNP K protein was found in mitochondria. The role of satellite I RNA in mitochondria remains to be elucidated.
Źródło:
Acta Biochimica Polonica; 2006, 53, 1; 169-178
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-4 z 4

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