- Tytuł:
- Small interfering RNA treatment can inhibit Cyprinid herpesvirus 3 associated cell death in vitro
- Autorzy:
-
Adamek, M.
Rauch, G.
Brogden, G.
Steinhagen, D. - Powiązania:
- https://bibliotekanauki.pl/articles/32253.pdf
- Data publikacji:
- 2014
- Wydawca:
- Polska Akademia Nauk. Czytelnia Czasopism PAN
- Opis:
- A Cyprinid herpesvirus 3 infection of carp induces a disease which causes substantial losses in carp culture. Here we present the use of a possible strategy for the management of the virus infection RNA interference based on small interfering RNAs. As a result of in vitro studies, we found that a mixture of short interfering RNAs specific for viral DNA enzyme synthesis and capsid proteins of the CyHV-3 can be a potential inhibitor of virus replication in fibroblastic cells. This gives the basis for the development of a combinatorial RNA interference strategy to treat CyHV-3 infections.
- Źródło:
-
Polish Journal of Veterinary Sciences; 2014, 17, 4
1505-1773 - Pojawia się w:
- Polish Journal of Veterinary Sciences
- Dostawca treści:
- Biblioteka Nauki
Artykuł