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    Wyświetlanie 1-13 z 13
    Tytuł:
    Cytotoxic and anti-cancer activity of the Cistus species of herbal plants
    Autorzy:
    Stępień, Agnieszka Ewa
    Powiązania:
    https://bibliotekanauki.pl/articles/454781.pdf
    Data publikacji:
    2017
    Wydawca:
    Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
    Tematy:
    anti-tumor activity
    Cistus species
    cytotoxic activity
    phytotherapeutics
    Opis:
    Aim. The aim of this paper is to provide an overview of the cytotoxic and anti-cancer properties of the major species of the genus Cistus. Materials and methods. Thirty four papers that discuss the medicinal history and current research of Cistus species as phytotherapeutics were used for this discussion. Literature analysis.The growing popularity of the Cistus species of herbs is mainly due to its anti-inflammatory, antimicrobial, antifungal and antioxidant properties. The results of in vitro studies indicate that the presence of pear extract significantly affects leukemia, leukemia, breast, colon, ovarian, pancreatic, and melanoma carcinomas. The significant growth inhibition of these cells, underlines its valuable anti-tumor properties and allows for the possibility of use as a therapeutic aid.
    Źródło:
    European Journal of Clinical and Experimental Medicine; 2017, 2; 165-168
    2544-2406
    2544-1361
    Pojawia się w:
    European Journal of Clinical and Experimental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Selected factors differentiating the forms of physical activity taken up or expected by the students of PSW in Biała Podlaska
    Autorzy:
    Stępień, Ewa
    Bergier, Barbara
    Niźnikowska, Ewelina
    Bergier, Józef
    Powiązania:
    https://bibliotekanauki.pl/articles/1054946.pdf
    Data publikacji:
    2015
    Wydawca:
    Uniwersytet Szczeciński. Wydawnictwo Naukowe Uniwersytetu Szczecińskiego
    Tematy:
    The International Physical Activity Questionnaire (IPAQ)
    physical activity
    students
    Opis:
    In view of new civilizational challenges of the 21st century, health promotion and education encouraging active participation in physical recreation, which should be implemented at all levels of education, within family, peer environment and local environment, become issues of particular importance. The research was carried out in the summer of 2013 and included 572 students of John Paul II State School of Higher Education in Biała Podlaska (PSW), of such degree courses as Tourism and Recreation, Public Health, Nursing, Rescue Medicine and Computer Science. The method used in the research was a diagnostic survey based on International Physical Activity Questionnaire (IPAQ). The aim of the study was to get to know the differentiation between the forms of recreational physical activity taken up and expected by the students of PWS and their gender, BMI and self-assessment of physical fitness. Basing on the results of the analysis it was concluded that the abovementioned independent variables have significant impact on the forms of physical activity chosen and expected by the surveyed. Studies of the literature on the subject and the results of our previous research entitle us to conclude that university students, who in the near future will constitute the intellectual elite of the country, should be aware of the influence of physical activity on general health, the importance of healthy lifestyle and their role in promoting healthy attitudes. However, the research showed that the students are not ready to perform such tasks, therefore the actions preparing them to lead a healthy lifestyle need to be intensified.
    Źródło:
    Central European Journal of Sport Sciences and Medicine; 2015, 10, 2; 87-94
    2300-9705
    2353-2807
    Pojawia się w:
    Central European Journal of Sport Sciences and Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Subjective and objective assessments of physical activity in professional active women aged 50 to 64 years
    Autorzy:
    Bergier, Barbara
    Gawlik, Krystyna
    Baj-Korpak, Joanna
    Stępień, Ewa
    Pocztarska-Głos, Agata
    Sidor, Mirosława
    Szepeluk, Adam
    Powiązania:
    https://bibliotekanauki.pl/articles/1030900.pdf
    Data publikacji:
    2020
    Wydawca:
    Uniwersytet Szczeciński. Wydawnictwo Naukowe Uniwersytetu Szczecińskiego
    Tematy:
    IPAQ-S
    accelerometer
    physical activity
    women aged 50 to 64 years
    Opis:
    Background: The aim of the study was to present data on subjective and objective assessments of physical activity in employed women and differences in their activity levels depending on age, education level, place of residence, financial status, and BMI. Another aim was to evaluate correlations of physical activity assessed subjectively and objectively with the aforementioned variables. Methods: Ninety employed women aged 50 to 64 years were divided into 3 groups. The International Physical Activity Questionnaire (IPAQ-S) was used for the subjective assessment, and the ActiGraph GT3X activity monitor was used for objective assessment. Results: The subjective assessment of total physical activity levels in the women was significantly higher than their objective assessment. The statistically significantly highest physical activity levels assessed by means of the questionnaire were found for women with the poorest financial status, or primary or secondary education levels and, for the assessments using accelerometers, the women with a BMI indicating overweight. A weak positive correlation (R = 0.25) was found between the total physical activity levels assessed subjectively and objectively. Conclusions: It seems that the use of only one tool for evaluation of physical activity level is not very conclusive. The use of both subjective and objective tools is needed to obtain reliable information about physical activity level.
    Źródło:
    Central European Journal of Sport Sciences and Medicine; 2020, 31, 3; 5-16
    2300-9705
    2353-2807
    Pojawia się w:
    Central European Journal of Sport Sciences and Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Evaluation of the Quality of Life of Women after Mastectomy
    Autorzy:
    Bolach, Bartosz
    Walowska, Jagoda
    Juskowiak, Ewa
    Stępień-Słodkowska, Marta
    Powiązania:
    https://bibliotekanauki.pl/articles/32443961.pdf
    Data publikacji:
    2024
    Wydawca:
    Uniwersytet Szczeciński. Wydawnictwo Naukowe Uniwersytetu Szczecińskiego
    Tematy:
    rehabilitation
    mastectomy
    breast cancer
    quality of life
    mental health
    social function
    Opis:
    Purpose The most frequent cancer among women in Poland and worldwide is breast cancer. The aim of the study was to assess the quality of women's life after unilateral and bilateral breast amputation. Research process The study included 47 women - 24 women after bilateral amputation and 23 unilateral amputees. Two questionnaires were used: European Organization for Research and Treatment of Cancer - Quality of Life Questionnaire: general and breast cancer module to measure the quality of life of patients treated for cancer. Results From among the assessed areas of quality of life, the sphere of emotional functioning was significantly disturbed. The passage of time improved the quality of life of the surveyed women. Thanks to early detection and treatment survival time is extended, however the disease becomes a chronic disorder affecting the psychosomatic sphere that changes the quality of life of these women.
    Źródło:
    Central European Journal of Sport Sciences and Medicine; 2024, 45; 55-64
    2300-9705
    2353-2807
    Pojawia się w:
    Central European Journal of Sport Sciences and Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Factors Associated with Physical Activity in People with Diabetes
    Autorzy:
    Sieńko-Awieraniów, Elżbieta
    Stępień-Słodkowska, Marta
    Latkowska, Agnieszka
    Głowacka, Ewa
    Powiązania:
    https://bibliotekanauki.pl/articles/1054668.pdf
    Data publikacji:
    2015
    Wydawca:
    Uniwersytet Szczeciński. Wydawnictwo Naukowe Uniwersytetu Szczecińskiego
    Tematy:
    Body Mass Index
    diabetes mellitus
    lifestyle
    physical activity
    Opis:
    Background: Diabetes mellitus is a chronic disease related to the occurrence of numerous metabolic disorders. Their common feature is hyperglycaemia, caused by insufficient insulin secretion or its malfunction. The World Health Organization states that 346 million people worldwide have diabetes. The studies in adults with type 2 diabetes clearly demonstrate that the change of lifestyle behaviours effectively improves glycemic control. The modifications of lifestyle habits, such as regular physical activity and healthier dietary habits prove to be beneficial for patients. The aim of this study was to determine the factors affecting the level of physical activity in people with diabetes mellitus. Methods: Research material consisted of the data gathered from a diagnostic survey, which was conducted in a form of a questionnaire. The study included 60 people with type 1 or type 2 diabetes. Results: Unfortunately, the results show that not all of them were active enough, which is so crucial for stabilizing the disease. Conclusions: The diagnosis of diabetes in the respondents resulted in more time being spent by them on physical activity, which resulted in the improvement of diabetes control and the normalization of body weight according to BMI, thus increasing the effectiveness of diabetes treatment and reducing complications. The frequency of the physical activity undertaken by the respondents prior to the disease was not related to gender, however, after the diagnosis, it was dependent on gender
    Źródło:
    Central European Journal of Sport Sciences and Medicine; 2015, 12, 4; 73-81
    2300-9705
    2353-2807
    Pojawia się w:
    Central European Journal of Sport Sciences and Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Application of the pyrolytic methylation to GC/MS profi ling of short-chain fatty acids in selected pharmaceutical preparations
    Zastosowanie pirolitycznej metylacji w oznaczaniu profi lu krótkołańcuchowych kwasów tłuszczowych w wybranych preparatach farmaceutycznych techniką GC/MS
    Autorzy:
    Chodurek, Ewa
    Kurkiewicz, Sławomir
    Dzierżęga-Lęcznar, Anna
    Stępień, Krystyna
    Dzierżewicz, Zofia
    Powiązania:
    https://bibliotekanauki.pl/articles/1038403.pdf
    Data publikacji:
    2011
    Wydawca:
    Śląski Uniwersytet Medyczny w Katowicach
    Tematy:
    pyrolysis
    gc/ms
    tmah derivatization
    scfa
    lab
    piroliza
    derywatyzacja
    tmah
    krótkołańcuchowe kwasy tłuszczowe
    bakterie kwasu
    mlekowego
    Opis:
    Lactic Acid Bacteria (LAB) belong to the normal fl ora of human alimentary tract and vaginal epithelium. The main products of LAB metabolism are short chain fatty acids (SCFA), which are known to have signifi cant infl uence on human health. The aim of this study was to examine the suitability of direct pyrolytic methylation in GC/MS profi ling of SCFA in the selected pharmaceutical preparations of LAB. For method optimization, standard SCFA samples consisting of acetic, propionic, butyric and lactic acids were pyrolyzed under various temperature conditions in the presence of methanolic solution of tetramethylammonium hydroxide (TMAH) as a derivatizing reagent. It was demonstrated that pyrolytic derivatization of standard SCFA to methyl esters was the most effi cient with the use 10% TMAH and the pyrolytic fi laments with Curie temperature of 480°C, when the pyrolysis cell was kept at 150°C. It was shown that the method is suitable for GC/MS qualitative analysis of SCFA profi le in the pharmaceutical preparations that contain LAB in lyophilized form.
    Bakterie kwasu mlekowego (Lactic Acid Bacteria – LAB) należą do naturalnej flory bakteryjnej zasiedlającej przewód pokarmowy oraz nabłonek pochwy człowieka. Głównym produktem metabolizmu LAB są krótkołańcuchowe kwasy tłuszczowe (short-chain fatty acids – SCFA) wywierające istotny wpływ na zdrowie człowieka. W pracy poddano ocenie przydatność techniki bezpośredniej metylacji pirolitycznej w oznaczaniu profi lu SCFA w wybranych preparatach farmaceutycznych LAB techniką GC/MS. W celu optymalizacji metody, wzorcowe próbki SCFA zawierające kwas octowy, propionowy, masłowy i mlekowy poddano pirolizie w obecności metanolowego roztworu wodorotlenku tetrametyloamoniowego (TMAH) w różnych warunkach temperaturowych. Stwierdzono, że derywatyzacja analizowanych kwasów tłuszczowych do estrów metylowych zachodziła z największą wydajnością pod wpływem 10% TMAH, gdy zastosowano druty pirolityczne o temperaturze Curie 480°C, a komorę pirolizera utrzymywano w temperaturze 150°C. Wykazano, że zoptymalizowana metoda jest przydatna w prowadzonej techniką GC/MS analizie jakościowej profi lu SCFA w wybranych preparatach farmaceutycznych zawierających LAB w formie liofi lizatu.
    Źródło:
    Annales Academiae Medicae Silesiensis; 2011, 65, 3; 16-20
    1734-025X
    Pojawia się w:
    Annales Academiae Medicae Silesiensis
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Regional strategies for pro-family policy in the care of rural child
    Autorzy:
    Sygit, Katarzyna
    Stępień-Słodkowska, Marta
    Krajewska-Pędzik, Anna
    Kaczmarczyk, Mariusz
    Pielichowska, Ewa
    Powiązania:
    https://bibliotekanauki.pl/articles/1054850.pdf
    Data publikacji:
    2014
    Wydawca:
    Uniwersytet Szczeciński. Wydawnictwo Naukowe Uniwersytetu Szczecińskiego
    Tematy:
    child
    family-supporting policy
    health care
    rural environment
    Opis:
    Health care of children and young people is part of a system of care of the so called “developmental age population.” In this system, prevention plays a key role. The aim of the study was, basing on the obtained results, to develop guidelines for the regional pro-family policy in care of a rural child. The study included children and young people of school age, from 14 to 19 years of age. Overall the analysis included 6,971 children and adolescents and 6,971 parents. Organization of health care of children and school adolescents depended on the solutions approved by individual founding bodies of Health Care Units and Regional Patients’ Funds. The withdrawal of nurses from school was observed. The tasks of prevention character performed previously by nurses employed at schools began to be implemented within the framework of primary health care in the child’s place of residence. For proper implementation of the tasks of school nurses and the proper development of school hygiene, it is important to establish a uniform and maximum number of pupils per one nurse, taking into account all circumstances, and to develop standards of care for the student, taking into account the age of the student, school type, and the region.
    Źródło:
    Central European Journal of Sport Sciences and Medicine; 2014, 7, 3; 73-80
    2300-9705
    2353-2807
    Pojawia się w:
    Central European Journal of Sport Sciences and Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Geochemistry of germanium in thermal waters of the Jelenia Góra geothermal system (Sudetes, Poland) : solute relationships and aquifer mineralogy
    Autorzy:
    Dobrzyński, Dariusz
    Tetfejer, Klaudia
    Stępień, Marcin
    Karasiński, Jakub
    Tupys, Andrii
    Słaby, Ewa
    Powiązania:
    https://bibliotekanauki.pl/articles/24459856.pdf
    Data publikacji:
    2023
    Wydawca:
    Polskie Towarzystwo Geologiczne
    Tematy:
    Germanium
    groundwater geochemistry
    geothermal water
    granite geochemistry
    Karkonosze Granite
    Jelenia Góra geothermal system
    Opis:
    A long-term (2004–2021) study of the chemical composition of thermal waters in the Jelenia Góra geothermal system provided information on a wide set of components. The subject of the present study is the geochemistry of germanium (Ge), which occurs in concentrations ranging from 2.7 to 6.3 μg/L in the waters studied. Interpretation of a set of 46 chemical analyses identified relationships between germanium and other elements in thermal waters from individual intakes. In the old thermal waters of Cieplice and Karpniki of deep circulation, germanium is derived from silicates and its concentration is controlled by the solubility of Ge-bearing quartz with an average Ge content of 1.5 μg/g. The source of germanium in the deep old thermal water at Staniszów is mainly sulphides, most likely arsenopyrite, but the secondary contribution of Ge from silicates (biotites, amphiboles) should not be ignored. The mineral phase, responsible for controlling Ge activity in this water, cannot yet be identified. The shallow thermal waters at Cieplice, which are a mixture of old thermal waters and modern waters, differ from the deep waters. Germanium in shallow waters probably is derived from silicates, but owing to mixing, there are no chemical equilibrium conditions; the concentration of Ge is determined by the dynamic equilibrium of the mixed water components. The modern water of intake no. 2 (Cieplice) differs from other shallow waters and also shows similarities to the Staniszów water. The germanium in the no. 2 water probably comes mainly from ferromagnesian minerals (biotite, amphiboles), although the influence of sulphides cannot be excluded. The relationships of germanium to other elements, including the Ge/Si ratio, appear to be effective indicators of hydrogeochemical conditions. Thermal waters from the different locations show both similarities and differences in chemical composition,especially of minor and trace components. At the present, still weak stage of recognition, the Jelenia Góra geothermal system can be treated as an area of occurrence of local systems responsible for the quantity and quality of thermal waters in individual intakes.
    Źródło:
    Annales Societatis Geologorum Poloniae; 2023, 93, 3; 323--344
    0208-9068
    Pojawia się w:
    Annales Societatis Geologorum Poloniae
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Yeast nuclear PET127 gene can suppress deletions of the SUV3 or DSS1 genes: An indication of a functional interaction between 3' and 5' ends of mitochondrial mRNAs
    Autorzy:
    Węgierski, Tomasz
    Dmochowska, Aleksandra
    Jabłonowska, Agnieszka
    Dziembowski, Andrzej
    Bartnik, Ewa
    Stępień, Piotr
    Powiązania:
    https://bibliotekanauki.pl/articles/1044752.pdf
    Data publikacji:
    1998
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Źródło:
    Acta Biochimica Polonica; 1998, 45, 4; 935-940
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Evolutionary conservation of the transcribed spacer sequences of the rDNA repeat unit in three species of the genus Aspergillus
    Autorzy:
    Borsuk, Piotr
    Gniadkowski, Marek
    Kucharski, Robert
    Bisko, Mariola
    Kanabus, Magdalena
    Stępień, Piotr
    Bartnik, Ewa
    Powiązania:
    https://bibliotekanauki.pl/articles/1045422.pdf
    Data publikacji:
    1994
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Źródło:
    Acta Biochimica Polonica; 1994, 41, 1; 73-77
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Microbial properties of soil fertilized by sewage sludge and cultivated with energy crops
    Właściwości mikrobiologiczne gleby nawożonej osadem ściekowym spod uprawy roślin energetycznych
    Autorzy:
    Górska, Ewa Beata
    Stępień, Wojciech
    Olejniczak, Izabella
    Pietkiewicz, Stefan
    Halaji, Hazem M.
    Kowalczyk, Paweł
    Powiązania:
    https://bibliotekanauki.pl/articles/470813.pdf
    Data publikacji:
    2016
    Wydawca:
    Uniwersytet Kardynała Stefana Wyszyńskiego w Warszawie
    Tematy:
    nawozy organiczne
    miskant
    mikroorganizmy
    ślazowiec pensylwański
    wierzba
    organic fertilizer
    Miscanthus
    microorganisms
    Virginia mallow
    Common osier willow
    Opis:
    Właściwości mikrobiologiczne gleby z dodatkiem osadu ściekowego, na której uprawiane są rośliny energetyczne, są mało poznane. Celem naszych badań była ocena wpływu nawożenia osadami ściekowymi na wybrane grupy fizjologiczne mikroorganizmów w glebie na której uprawiano następujące rośliny: miskant (miskant olbrzymi Greef et Ger), ślazowiec pensylwański (ślazowiec pensylwański (L.) Rusby) oraz wierzba (Alix viminalis L.). Osady ściekowe stosowano w dwóch dawkach 10 i 20 t / ha suchej masy (DW). W glebie oznaczono ogólną liczebność bakterii grupy coli, przetrwalnikujących bakterii redukujących siarczany, Proteus sp., saprofitycznych, termofilnych i tlenowych bakterii tworzących formy przetrwalnikowe. W zależności od dawki osad ściekowy zwiększył liczebność bakterii grupy coli i endosporowych bakterii redukujących siarczany i stymulował wzrost bakterii saprofitycznych i termofilnych. Uprawa miskanta ograniczyła liczbę bakterii z grupy coli natomiast ślazowca pensylwańskiego i miskanta zmniejszyła liczbę bakterii przetrwalnikujących i redukujących siarczany. Wierzba stymulowała wzrost bakterii saprofitycznych w glebie a ślazowiec pensylwański liczbę bakterii przetrwalnikowych. Nasze wyniki wykazały, że aktywność mikrobiologiczna gleby wyrażona liczebnością wybranych grup bakterii, zależy nie tylko od stosowanej dawki osadu ściekowego, lecz również od uprawianej rośliny energetycznej.
    The microbial activity of soil enriched with sewage sludge and cultivated with energy crops, is little known. The aim of this study was to assess the impact of sewage sludge fertilization on selected microorganisms in soil cultivated with the following crops: Miscanthus (Miscanthus x giganteus Greef et Deu), Virginia mallow (Sida hermaphrodita (L.) Rusby) and Common Osier willow (Salix viminalis L.). Sewage sludge was used in two rates 10 and 20 t/ha dry weight (DW). The numbers of total coliforms bacteria, sulphate-reducing spore-forming bacteria, Proteus sp., saprophytic, thermophilic and aerobic spore-forming bacteria were examined. Sewage sludge increased the number of coliforms and sulphate-reducing spore-forming bacteria, and stimulated the growth of saprophytic and thermophilic bacteria. Cultivation of Miscanthus limited the number of coliforms bacteria, while Virginia mallow and Miscanthus reduced the number of sulphate- -reducing spore-forming bacteria. Common Osier willow stimulated the growth of saprophytic bacteria in the soil, while Virginia mallow the number of spore-forming bacteria. Our results revealed that microbial activity of soil expressed as the number of selected bacterial groups, depends not only on the applied rate of sewage sludge fertilizer, but also on the cultivated energy crop.
    Źródło:
    Studia Ecologiae et Bioethicae; 2016, 14, 3; 131-142
    1733-1218
    Pojawia się w:
    Studia Ecologiae et Bioethicae
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    A human putative Suv3-like RNA helicase is conserved between Rhodobacter and all eukaryotes
    Autorzy:
    Dmochowska, Aleksandra
    Kalita, Katarzyna
    Krawczyk, Michał
    Golik, Paweł
    Mroczek, Katarzyna
    Lazowska, Jaga
    Stępień, Piotr
    Bartnik, Ewa
    Powiązania:
    https://bibliotekanauki.pl/articles/1044553.pdf
    Data publikacji:
    1999
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Źródło:
    Acta Biochimica Polonica; 1999, 46, 1; 155-162
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Differential stability of mitochondrial mRNA in HeLa cells
    Autorzy:
    Piechota, Janusz
    Tomecki, Rafał
    Gewartowski, Kamil
    Szczęsny, Roman
    Dmochowska, Aleksandra
    Kudła, Marek
    Dybczyńska, Lien
    Stepien, Piotr
    Bartnik, Ewa
    Powiązania:
    https://bibliotekanauki.pl/articles/1041282.pdf
    Data publikacji:
    2006
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    polyadenylation
    HeLa
    mitochondria
    poly(A) polymerase
    mRNA turnover
    Opis:
    The physiological significance and metabolism of oligoadenylated and polyadenylated human mitochondrial mRNAs are not known to date. After study of eight mitochondrial transcripts (ND1, ND2, ND3, ND5, CO1, CO2, ATP6/8 and Cyt. b) we found a direct correlation between the half-lives of mitochondrial mRNAs and their steady-state levels. Investigation of the mt-mRNA decay after thiamphenicol treatment indicated that three transcripts (ND2, ND3 and Cyt. b) are significantly stabilized after inhibition of mitochondrial translation. Careful analysis one of them, ND3, showed that inaccurate processing of the H-strand RNA precursor may occasionally occur between the ND3 and tRNAArg locus leading to synthesis of ND3 mRNAs lacking the STOP codon. However, analysis of the oligo(A) fraction observed in case of the ND3 indicates that partially polyadenylated mRNAs are linked rather to the transcription process than to the translation-dependent deadenylation. Analysis of ND3 mRNA turnover in cells with siRNA-mediated knock-down of the mitochondrial poly(A) polymerase shows that strongly decreased polyadenylation does not markedly affect the decay of this transcript. We present a model where oligoadenylated mitochondrial transcripts are precursors of molecules containing full length poly(A) tails.
    Źródło:
    Acta Biochimica Polonica; 2006, 53, 1; 157-168
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
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