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    Wyświetlanie 1-6 z 6
    Tytuł:
    Biochemiczna diagnostyka nowotworów narządu płciowego kobiety – co nowego?
    Biochemical diagnostics of gynecological malignancies – what’s new?
    Autorzy:
    Kamińska, Janina
    Kowalska, Maria
    Kotowicz, Beata
    Fuksiewicz, Małgorzata
    Siedlecka, Alicja
    Bidziński, Mariusz
    Powiązania:
    https://bibliotekanauki.pl/articles/908180.pdf
    Data publikacji:
    2006
    Wydawca:
    Medical Communications
    Tematy:
    cervical carcinoma
    cytokines
    diagnostic sensitivity
    markers of bone turnover
    tumor markers
    Opis:
    The analysis of the utility of serum SCC determination, combined with other tumor markers and cytokine assessment in cervical cancer patients, was performed. However, only CA 125 levels were found to relate to the histopathological type of the tumor, and were higher in adenocarcinoma. In addition, in patients with adenocarcinoma, CA 125 presented higher diagnostic sensitivity than CEA, standard tumor marker for cervical cancer. We have also shown that complementary IL-6 and SCC assessment in patients with cervical cancer improve the diagnostic sensitivity, independent of histopathological type. This would be especially important for early diagnostics and monitoring of patients. We have also demonstrated the possible use of bone metabolism markers in patients after oncological treatment with posttreatment osteoporosis, which is a common side effect of cancer treatment. Actually, bone metabolism markers join the array of tumor markers, to monitor osteoporosis treatment. For the monitoring purposes, these markers are more efficient than densitometry methods. Our preliminary results on osteocalcin, PINP and Ctx point at PINP as the most promising marker.
    W pracy analizowano przydatność oznaczania SCC z innymi markerami nowotworowymi i cytokinami w surowicy krwi chorych na raka szyjki macicy. Analizując zależność pomiędzy stężeniami badanych markerów nowotworowych i cytokin a typem histopatologicznym, stwierdzono, że stężenia CA 125 były istotnie wyższe u chorych na gruczołowego raka szyjki macicy. Ponadto wykazano, że u chorych na gruczołowego raka szyjki macicy oznaczanie stężeń CA 125 ma większą przydatność diagnostyczną niż oznaczenia CEA, który uznawany jest za standardowy marker dla tego nowotworu. Stwierdzono również, że oznaczanie IL-6 z SCC u chorych na raka szyjki macicy, niezależnie od typu histopatologicznego, zwiększa czułość diagnostyczną, co ma szczególne znaczenie we wczesnych stopniach zaawansowania klinicznego i może być przydatne do monitorowania wyników leczenia. Omówiono także możliwość wykorzystania markerów obrotu kostnego po leczeniu onkologicznym, które jest często przyczyną licznych powikłań, między innymi takich jak osteoporoza. W chwili obecnej panel markerów nowotworowych został poszerzony o markery obrotu kostnego, które mogą być przydatne w ocenie skuteczności leczenia osteoporozy. Od niedawna stosowane markery obrotu kostnego umożliwiają ocenę skuteczności leczenia w znacznie krótszym czasie niż metody densytometryczne. Do najczęściej wykorzystywanych markerów należą: osteokalcyna, PINP i Ctx. Wyniki naszych wstępnych badań sugerują jednak, że największą przydatność ma oznaczanie stężeń PINP.
    Źródło:
    Ginekologia Onkologiczna; 2006, 4, 1; 10-13
    1731-5379
    Pojawia się w:
    Ginekologia Onkologiczna
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Impedance cardiography – Old method, new opportunities. Part I. Clinical applications
    Autorzy:
    Siedlecka, Jadwiga
    Siedlecki, Patryk
    Bortkiewicz, Alicja
    Powiązania:
    https://bibliotekanauki.pl/articles/2177029.pdf
    Data publikacji:
    2015-02-24
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    impedance cardiography
    hypertension
    heart failure
    dyspnea
    cardiac rehabilitation
    Opis:
    Monitoring of cardiovascular hemodynamic changes requires a very expensive and highly specialized equipment and skilled medical personnel. Up to the present time, an inexpensive, non-invasive and easy-to-use method which, like Doppler echocardiography, magnetic resonance angiography or radionuclide imaging, would assess hemodynamics of the cardiovascular system was not available. A method known as impedance cardiography (ICG) or thoracic electrical bioimpedance cardiography (TEBC) meets those criteria. It is non-invasive, which is of a particular advantage over the conventional methods that require catheterization. As a result, the patient is not at risk of possible complications and the procedure is less expensive and easier. Impedance cardiography, despite its non-invasive character, has not been so far extensively used for monitoring of hemodynamic parameters in hospitalized patients. Various authors report that attempts have been continued to compare the results from ICG and those obtained by other diagnostic methods. This paper presents the use of impedance cardiography in diagnosis of hypertension, cardiac insufficiency, differentiating the causes of acute dyspnea, as well as in assessing the effects of cardiac rehabilitation in patients with heart failure.
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2015, 28, 1; 27-33
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Impedance cardiography – Old method, new opportunities. Part II. Testing of cardiovascular response to various factors of work environment
    Autorzy:
    Siedlecka, Jadwiga
    Siedlecki, Patryk
    Bortkiewicz, Alicja
    Powiązania:
    https://bibliotekanauki.pl/articles/2177030.pdf
    Data publikacji:
    2015-02-24
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    impedance cardiography
    cardiovascular system
    work environment
    occupational stress
    physical activity
    drivers’ health
    Opis:
    Impedance cardiography seems to be a very good, although underappreciated diagnostic method. What may distinguish it from among the many research methods is the fact that it enables non-invasive monitoring of cardiac output, stroke volume and systemic vascular resistance. Holter recording of the hemodynamic parameters makes it possible to study them not only in stationary (hospital, outpatient clinic) conditions, but also during household or professional activities, e.g., during road vehicle driving. Assessment of the trends of changes in the circulatory system of the employee at work makes it possible to judge whether the type of work performed by the worker is well tolerated – whether it is not too hard or too stressful. This is important, therefore, impedance cardiography can be extensively used in occupational medicine. Provision of preventive care to workers according to current standards requires, on the one hand, the use of the latest diagnostic methods while, on the other hand, the methods must be inexpensive, because otherwise the employer would not be able or willing to pay the associated costs. Impedance cardiography meets those criteria; however, few data is available in literature worldwide on the use of this method in the research on the impact of occupational work on cardiovascular responses of the employees. This work reports the use of impedance cardiography in studies on the various aspects of work environment.
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2015, 28, 1; 34-41
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Can alveolar hypoventilation due to kyphoscoliosis be a contraindication to driving?
    Autorzy:
    Kania, Aleksander
    Nastałek, Paweł
    Celejewska-Wójcik, Natalia
    Sładek, Krzysztof
    Kosobudzki, Marcin
    Bortkiewicz, Alicja
    Siedlecka, Jadwiga
    Powiązania:
    https://bibliotekanauki.pl/articles/2161948.pdf
    Data publikacji:
    2019-10-16
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    scoliosis
    non-invasive ventilation
    professional driving
    traffic-related accidents
    hypoventilation
    sleep apnoea
    Opis:
    Road accidents are among the main fatalities worldwide and drowsy driving is a significant cause of road deaths where drivers are at fault. There are well known diseases which impair sensory and cognitive functions and can cause sleepiness during driving. Such diseases can be an important contraindication to driving because they may have an adverse effect on its safety. Thus, medical examinations for drivers should also be directed at identifying any possible conditions posing risks for driving safety. Occupational medicine specialists should look for symptoms of locomotor and sleep-related breathing disorders as these are medical conditions which could preclude a person from driving. In this case report, the authors describe a professional driver with chest deformity and present a pioneering attempt at assessing his medical fitness to drive. It is also explained why scoliosis can impair driving ability and how it should be diagnosed and treated. Finally, the authors describe how they used driving simulator tests as part of their diagnosis and suggest a relevant treatment regimen. Int J Occup Med Environ Health. 2019;32(5):735–45
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2019, 32, 5; 735-745
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Dietary habits and myocardial infarction in occupationally active men
    Autorzy:
    Bortkiewicz, Alicja
    Gadzicka, Elżbieta
    Siedlecka, Jadwiga
    Szyjkowska, Agata
    Viebig, Piotr
    Wranicz, Jerzy K.
    Kurpesa, Małgorzata
    Trzos, Ewa
    Makowiec-Dąbrowska, Teresa
    Powiązania:
    https://bibliotekanauki.pl/articles/2161938.pdf
    Data publikacji:
    2019-11-15
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    nutrition
    food
    acute myocardial infarction
    physical work
    mental work
    body mass index
    Opis:
    Objectives Only a few studies have been undertaken to analyze the dietary habits of people with cardiovascular diseases. The aim of this study was to evaluate the dietary behaviors of working people who were hospitalized due to experiencing the first acute cardiovascular incident. Material and Methods In the study, the Functional Activity Questionnaire was used. The study was conducted in 2 groups. The first group included all the men hospitalized during 1 year (January–December 2009) in 2 clinics of cardiology, who were professionally active until the first myocardial infarction (MI). It comprised 243 men aged 26–70 years. The reference group consisted of 403 men, blue- and white-collar workers, aged 35–65 years. Results The body mass index of the MI patients was significantly higher (p = 0.006). The frequency of consumption of particular products in the MI group and in the reference group differed significantly for 11 of 21 products. The MI patients significantly less frequently reported the daily consumption of fruit, raw vegetables, cheese, vegetable oils and fish. In this group, the consumption of salty (p = 0.0226) or fatty (p < 0.0001) foods was significantly higher. It was shown that, after adjusting for age, education and the type of work, the daily consumption of fish, salads and cooked vegetables, as well as fruit and vegetable oils, significantly reduced the risk of myocardial infarction. An increased MI risk was, in turn, associated with obesity and preference for fatty foods. Conclusions The authors found that diet significantly modified the MI risk in the examined workers. This indicates that an important aspect of prevention activities among working people should involve education about proper dietary habits. Int J Occup Med Environ Health. 2019;32(6):853–63
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2019, 32, 6; 853-863
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Analysis of bus drivers reaction to simulated traffic collision situations – eye-tracking studies
    Autorzy:
    Bortkiewicz, Alicja
    Gadzicka, Elżbieta
    Siedlecka, Jadwiga
    Kosobudzki, Marcin
    Dania, Marta
    Szymczak, Wiesław
    Jóźwiak, Zbigniew
    Szyjkowska, Agata
    Viebig, Piotr
    Pas-Wyroślak, Alicja
    Makowiec-Dąbrowska, Teresa
    Kapitaniak, Bronisław
    Hickman, Jeffrey S.
    Powiązania:
    https://bibliotekanauki.pl/articles/2161982.pdf
    Data publikacji:
    2019-04-03
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    road safety
    driver
    eye-tracking
    visual strategy
    accidents
    driving simulator
    Opis:
    Objectives The aim of the study was to establish whether the driver’s visual strategy may influence a driver’s behavior to avoid a crash in a high-risk situation. Any published papers on drivers’ visual strategies just before a crash were not found. Material and Methods Tests were performed using a high-tech driving bus simulator. Participants comprised 45 men drivers, aged 43.5±7.9 years old, seniority as a bus driver of 13.3±8.6 years. The tests were preceded by medical examinations: general, neurological and ophthalmological. Each participant drove the same city route for approximately 40 min (entire route – ER). In the final phase, a collision situation was simulated (a phantom car blocked the participant’s right of way). Driver’s visual strategy was analyzed using the FaceLab device with 2 cameras during ER and just before collision. The field-of-view covered by camera 1 was divided into 8 regions, by camera 2 into 10 regions. The distribution of gazes in regions was a criterion of visual strategy. Results Thirty-five drivers completed the simulated driving test, 14 escaped the collision, 21 crashed. These groups differed only in resting systolic blood pressure before the test. The analysis of covariance, after adjusting to this factor, indicated that during the ER visual strategy recorded by camera 1 did not differ between groups, in camera 2 the drivers in the crash group fixed their gaze more frequently (p = 0.049) in region 3 (close part of the road in front of the windshield). Just before the collision drivers who escaped the collision fixed their gaze significantly more often in region 6 (left side of the road) in camera 1 and in region 6 (in front of the windshield,) and region 10 (right side) in camera 2. Conclusions The visual strategy has an impact on the road safety. The analysis of visual strategies may be a useful tool for the training of drivers. Int J Occup Med Environ Health. 2019;32(2):161–74
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2019, 32, 2; 161-174
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-6 z 6

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