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    Tytuł:
    Education for Sustainable Development. in the Academic Education in Poland in the Light of the Education for Sustainable Development Strategy
    Autorzy:
    Sadowska-Konczal, Agnieszka
    Powiązania:
    https://bibliotekanauki.pl/articles/472546.pdf
    Data publikacji:
    2014
    Wydawca:
    Uniwersytet Pedagogiczny im. Komisji Edukacji Narodowej w Krakowie
    Tematy:
    education for sustainable development,
    sustainable development,
    strategy for education for sustainable development
    Źródło:
    Annales Universitatis Paedagogicae Cracoviensis. Studia ad Didacticam Biologiae Pertinentia; 2014, IV; 17-28
    2083-7267
    2450-3487
    Pojawia się w:
    Annales Universitatis Paedagogicae Cracoviensis. Studia ad Didacticam Biologiae Pertinentia
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The effect of calorie restriction on the anthropometric parameters, HOMA-IR index, and lipid profile of female office workers with overweight and obesity: a preliminary study
    Autorzy:
    Sadowska-Krępa, Ewa
    Gdańska, Agnieszka
    Přidalová, Miroslava
    Rozpara, Michał
    Grabara, Małgorzata
    Powiązania:
    https://bibliotekanauki.pl/articles/2152975.pdf
    Data publikacji:
    2022
    Wydawca:
    Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
    Tematy:
    insulin resistance
    lipid profile
    reduction diet
    snacking
    coronavirus pandemic
    low physical activity level
    Opis:
    Objectives This study evaluates the effect of a 3-month calorie restriction (CR) without snacking on the anthropometric parameters, Homeostatic Model Assesment of Insulin Resistance (HOMA-IR), and lipid profiles of female office workers with overweight or obesity, whose physical activity was limited during the COVID-19 pandemic lockdown. Material and Methods Forty-eight women aged 20–38 years (28.9±5.24) with low physical activity levels were divided into a non-snacking (NS) group (N = 21) and a snacking (S) group (N = 27) prior to the dietary intervention. Their daily energy intake during the intervention was lowered by 30% compared with the baseline level, and the proportion of polyunsaturated fatty acids and fiber in their diet was increased (to >30 g/day). The proportion of saturated fatty acids and simple carbohydrates was also reduced. The study participants were assessed at the baseline and post-intervention for anthropometric variables (body weight, body fat percentage BMI, waist circumference, hip circumference, waist-to-hip ratio) and the concentrations of insulin, total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C). Moreover, the values for HOMA-IR, the atherogenic index of plasma (AIP), and the ratios of TC/HDL-C, TG/HDL-C, and LDL-C/HDL-C were calculated. Results All anthropometric parameter values obtained post-intervention were lower than the baseline in both groups. The serum insulin concentration and HOMA-IR decreased respectively by an average of 6% and 25% in the NS group and 37% and 45% in the S group. The lipid profiles of all participants improved significantly, with the LDL-C concentration showing a more promising trend in the S group (decrease by 27%) than in the NS group (17%). Conclusions The study showed that CR improved the anthropometric parameters, HOMA-IR index, and lipid profiles of all participants.
    Źródło:
    International Journal of Occupational Medicine and Environmental Health; 2022, 35, 6; 693-706
    1232-1087
    1896-494X
    Pojawia się w:
    International Journal of Occupational Medicine and Environmental Health
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The comparison between the two most common histological subtypes of breast cancer - invasive ductal and invasive lobular breast carcinoma
    Autorzy:
    Fudalej, Marta
    Sobiborowicz-Sadowska, Aleksandra
    Mormul, Agata
    Jopek, Sylwia
    Borowiec, Agnieszka
    Sikorski, Piotr
    Patera, Janusz
    Deptała, Andrzej
    Badowska-Kozakiewicz, Anna M.
    Powiązania:
    https://bibliotekanauki.pl/articles/44426576.pdf
    Data publikacji:
    2024-04-07
    Wydawca:
    Medical Education
    Tematy:
    immunohistochemistry
    invasive lobular carcinoma
    invasive ductal carcinoma
    Opis:
    Introduction: Invasive lobular carcinoma (ILC) occurs in 5–15% of all cases of breast cancer. In most studies, it is found to be more common among older patients, form larger tumours and present with ill-defined margins, in comparison to invasive ductal carcinoma (IDC). Material and methods: Histological preparations were obtained from 651 patients suffering from breast cancer. Preparations stained with hematoxylin and eosin were used to identify tumour type and grading. Samples underwent a basic molecular profile evaluation encompassing ER (oestrogen receptor), PR (progesterone receptor) and human epidermal growth factor receptor 2 (HER2) expression. Results: 592 cases of IDC and 59 cases of ILC were detected. The median age was 60 in both groups. While there were no statistically significant differences between IDC and ILC in nodal status and tumour size for all age groups, IDC was more frequently diagnosed at higher grading (G3). G3 accounted for 32% of all IDC specimens compared to only 13% of ILC specimens. In both groups, the most prevalent combination of hormone receptors was ER+/PR+/HER2-. The differences in ER and PR expression were statistically significant; both were assessed as positive in most ILC cases and just over half of IDC. No HER2 amplification was noted in most cases in both cancer subtypes. Conclusions: In our study, IDC and ILC showed no difference with respect to patients’ median age at the diagnosis and local disease advancement defined by TNM. ILC cases were hormone-dependent and HER2-negative more frequently than IDC. Grade 3 tumours accounted for a higher proportion of IDC cases. This was in line with several other clinicopathological analyses of breast cancer. However, there are also several papers indicating ILC’s association with favourable prognostic features, not only in terms of hormone receptors and HER2 expression but also tumour size and nodal involvement. This underlines the fact that clear differences between IDC and ILC prognosis still cannot be established.
    Źródło:
    OncoReview; 2024, 14, 1; 9-15
    2450-6125
    Pojawia się w:
    OncoReview
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-3 z 3

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