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    Wyświetlanie 1-4 z 4
    Tytuł:
    Optimization of Complex Operations in the Supply Chain Through the Implementation of Advanced Planning System
    Autorzy:
    Rut, Joanna
    Kulińska, Ewa
    Powiązania:
    https://bibliotekanauki.pl/articles/504299.pdf
    Data publikacji:
    2018
    Wydawca:
    Międzynarodowa Wyższa Szkoła Logistyki i Transportu
    Tematy:
    enterprise
    optimization
    supply chain
    information flow
    IT systems
    APS
    planning
    scheduling
    Opis:
    Contemporary variability of the environment and market dynamics force enterprises to optimize operations in the supply chain. Advanced IT systems such as the Advanced Planning System are a powerful tool that supports many areas in supply chain management. An efficient supply chain is a key element in gaining a competitive advantage in the market. Therefore, the foundation of the material and information flow regulation in manufacturing enterprises is the efficient exchange of information with both the internal and external environment of the organization. The article presents the optimization process of complex operations taking place in the supply chain by implementing the Advanced Planning System in the examined enterprise. It also enumerates significant benefits resulting from the implementation.
    Źródło:
    Logistics and Transport; 2018, 40, 4; 91-96
    1734-2015
    Pojawia się w:
    Logistics and Transport
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Improvement of the manufacturing and logistic process in the researched company
    Doskonalenie procesu produkcji I logistyki w badanym przedsiębiorstwie
    Autorzy:
    Rut, Joanna
    Wengel, Monika
    Powiązania:
    https://bibliotekanauki.pl/articles/1384808.pdf
    Data publikacji:
    2019
    Wydawca:
    Polskie Wydawnictwo Ekonomiczne
    Tematy:
    improvement
    manufacturing process
    logistics
    IT systems
    lean production
    doskonalenie
    proces produkcji
    logistyka
    systemy IT
    Opis:
    Manufacturing and logistics process in conditions of the contemporary market must be multidimensional and multicriterial. Activities associated with production and logistics are closely related. Improvement of the manufacturing process and logistics areas in enterprises has a great importance and can bring a lot of benefits. Each optimization of the manufacturing and logistics proces should be analyzed, adapted to needs of the given enterprise and successively implemented. The article describes proposals to improve the manufacturing and Logistics process in researched enterprise, through identification of functional problems. In addition, indicates important possible benefits, resulting from the use of tools, systems and techniques to optimize production and logistics areas in the organization.
    W warunkach współczesnego rynku proces produkcji i logistyki musi mieć charakter wielowymiarowy i wielokryterialny. Działania związane z produkcją i logistyką są ze sobą ściśle powiązane. Doskonalenie procesu produkcji i obszarów logistyki w przedsiębiorstwach ma ogromne znaczenie i może przynieść wiele korzyści. Każda optymalizacja procesu produkcji i logistyki powinna być przeanalizowana, dostosowana do potrzeb danego przedsiębiorstwa i sukcesywnie wdrażana. Niniejszy artykuł przedstawia propozycje doskonalenia procesu produkcji i logistyki w badanym przedsiębiorstwie, poprzez identyfikację problemów funkcjonalnych. Ponadto wskazuje istotne możliwe do uzyskania korzyści, wynikające z zastosowania narzędzi, systemów i technik optymalizujących obszary produkcji i logistyki w organizacji.
    Źródło:
    Gospodarka Materiałowa i Logistyka; 2019, 12; 47-52
    1231-2037
    Pojawia się w:
    Gospodarka Materiałowa i Logistyka
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Neutrophil-lymphocyte ratio and creatinine reduction ratio predict good early graft function among adult cadaveric donor renal transplant recipients. Single institution series
    Autorzy:
    Hogendorf, Piotr
    Suska, Anna
    Skulimowski, Aleksander
    Rut, Joanna
    Grochowska, Monika
    Wencel, Aleksandra
    Dziwisz, Filip
    Nowicki, Michał
    Szymański, Dariusz
    Poznańska, Grażyna
    Durczyński, Adam
    Strzelczyk, Janusz
    Powiązania:
    https://bibliotekanauki.pl/articles/1392878.pdf
    Data publikacji:
    2018
    Wydawca:
    Index Copernicus International
    Tematy:
    neutrophil-lymphocyte ratio
    creatinine reduction ratio
    graft function
    cadaveric donor
    delayed graft function kidney transplant
    Opis:
    The Background Delayed graft function (DGF) is a common complication following kidney transplantation and is associated with ischemia-reperfusion injury (IRI). Lymphocytes contribute to the pathogenesis of IRI and ischemia-reperfusion related to delayed graft function. Materials and Methods : 135 Caucasian patients received a kidney graft from deceased heart-beating organ donors. We divided patients into 2 groups - patients with the eGFR>=30 on the 21st day post-transplantation (n=36) and patients with the eGFR<30 on the 21st day post-transplantation (n=99) to assess kidney graft function. We measured serum creatinine levels on 1st and 2nd post-transplant day and preoperative levels of monocytes, lymphocytes, platelets, and neutrophils and their ratios. Results: We have found statistically significant differences between the eGFR<30 and the eGFR>=30 groups in the average lnLymphocytes (0.36 +/-0.6 vs. -0.016 +/-0.74, respectively p=0.004) lnNLR (1,27 +/-0.92 vs. 1.73+/-1.08 p=0.016) lnLMR (1.01 +/-0.57 vs. 0.73 +/-0.64 p=0.02), lnPLR (4.97 +/-0.55 vs. 5.26 +/- 0.67 p=0.023), and CCR 2% (-20.20 +/- 21.55 vs. -4.29 +/- 29.62 p=0.004. In the univariate analysis, factors of lnLymphocytes >=0.22 (OR=0.331 95%CI 0.151-0.728 p=0.006), lnLMR>=1.4 (OR=0.255 95%CI 0.072-0.903 p=0.034) were associated with a worse graft function, while lnNLR>=1.05 (OR=2.653 95%CI 1.158-6,078 p=0.021), lnPLR>=5.15 (OR=2.536 95%CI 1.155-5.566 p=0.02) and CRR2 (OR=3.286 95% CI 1.359-7.944 p=0.008) indicated a better graft function. Conclusion: A higher absolute lymphocyte count (lnLymphocytes) and lnLMR, as well as lower lnNLR and lnPLR were associated with a lower eGFR on the 21st day after kidney transplantation. In the multivariate analysis, CRR2 in combination with either lnLymphocytes, lnNLR or lnPLR improved the accuracy of detecting patients with poor graft function.
    Źródło:
    Polish Journal of Surgery; 2018, 90, 2; 28-33
    0032-373X
    2299-2847
    Pojawia się w:
    Polish Journal of Surgery
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Elevated preoperative levels of CA 19-9 and CA 125 predicts overall survival time in the pancreatic adenocarcinoma. Single institution series.
    Autorzy:
    Hogendorf, Piotr
    Skulimowski, Aleksander
    Durczyński, Adam
    Kumor, Anna
    Poznańska, Grażyna
    Poznańska, Agnieszka
    Oleśna, Aleksandra
    Rut, Joanna
    Øvereng Juliebø, Siri
    Szmiel, Aneta
    Pirowski, Wojciech
    Strzelczyk, Janusz
    Powiązania:
    https://bibliotekanauki.pl/articles/1391695.pdf
    Data publikacji:
    2020
    Wydawca:
    Index Copernicus International
    Tematy:
    general surgery
    pancreatic neoplasms
    biomarkers
    prognostic factors
    Opis:
    Introduction: Pancreatic cancer is a devastating disease, being the seventh cause of cancer-related deaths worldwide. Its aggressiveness is due to its specific biology and the late diagnosis of cancer. Therefore, the prognosis for patients suffering from this cancer is dismal, with 5-year overall survival rate of around 6–10%. Up to date, only a complete surgical resection of the cancerous entity warrants a significant improvement in patients’ survival. Nevertheless, the pancreatic cancer’s biology is still not fully elucidated, so that the accuracy of prognosis for certain patients is highly uncertain. Consequently, the importance of both clinical and basic research aiming to reveal the crucial molecular factors affecting long-term prognosis should be highlighted. There is a growing number of evidence that biomarkers of PC not only reflect the presence of tumor itself but also present a “hint” regarding its physiology. Thus the aim of this study was to assess the levels of commonly measured biomarkers and their influence on patients’ overall survival. Materials and methods: The retrospective analysis of data on 129 patients admitted to our Department due to the diagnosis of pancreatic cancer was carried out. On the day of admission all the patients had their levels of CA19-9, CA125, CEA and CA15-3 measured. The overall survival (OS) was defined as time elapsing from the day of admission to the day of death. The Kaplan- Meier curves were built for all potential factors, Cox regression model was applied to carry out a multivariate analysis. Results: We retrospectively analyzed 129 patients with a mean age of 62 years. As many as 95 of them had an unresectable lesion and 34 underwent curative operation. In total, the analyzed patient group was characterized by a median survival of 7 months and 12 days. Cumulative 1-year, 2-year and 4-year survival rates were 35%, 16% and 15%, respectively. In univariate analysis, factors such as age >= 60, inoperable lesion, CA19-9 >= 200, CA125 >= 20 and Neutrophile to Lymphocyte Ratio (NLR) >= 5 were associated with a lower median OS. In multivariate analysis, three factors, CA19-9 >= 200, CA125 >= 20 and age >= 60, were found to be statistically significant. Indeed, patients possessing all of them noted much poorer outcomes regarding OS factors: 89 days versus 235 days for the other patients (log rank test P = 0.02). Conclusions: Our study fortifies the evidence that preoperative levels of CA19-9 and CA125 have a direct influence on the longterm OS. Interestingly, in our patient group, the correlation of biomarkers with OS was higher than that of resectability. However, our study has some limitations regarding, for instance, the lack of data on chemotherapy, comorbidities etc. In the view of recent molecular studies on mucin involvement in PC development, it provides a strong clinical evidence to prove their importance.
    Źródło:
    Polish Journal of Surgery; 2020, 92, 3; 32-38
    0032-373X
    2299-2847
    Pojawia się w:
    Polish Journal of Surgery
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-4 z 4

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