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Wyświetlanie 1-8 z 8
Tytuł:
The IT strategy and perception of barriers faced by Polish manufacturing SMEs in the implementation of cloud computing
Autorzy:
Pamuła, Anna
Powiązania:
https://bibliotekanauki.pl/articles/1845503.pdf
Data publikacji:
2020
Wydawca:
Politechnika Śląska. Wydawnictwo Politechniki Śląskiej
Tematy:
cloud computing
IT strategy
manufacturing
IT
strategia IT
produkcja
Opis:
Purpose: The aim of the paper was to analyse barriers to adopting Cloud Computing solutions by small and medium-sized manufacturing enterprises in Poland. Design/methodology/approach: The paper is based on the review of literature and studies on the application of Cloud Computing solutions in small and medium-sized enterprises as well as the results of own research among this group of enterprises. Quantitative research was carried out using a survey questionnaire in December 2017 – February 2018, with the use of the CATI technique, among manufacturing enterprises in Poland. Findings: Investigated SMEs see fewer and fewer barriers in the implementation of new CC models. In the surveyed group most barriers are perceived by less than 30% of respondents. Research limitations/implications: A certain limitation of the study is that no separate Digital Business Strategy or Agile Strategy were considered, assuming that they were included in the adopted survey options. This result could have been influenced by the period in which the research was carried out, which is less than half a year before the entry into force of the General Data Protection Regulation – GDPR. Originality/value: The perception of barriers is discussed taking into account the application of an IT Strategy and the party responsible for the implementation.
Źródło:
Zeszyty Naukowe. Organizacja i Zarządzanie / Politechnika Śląska; 2020, 149; 463-479
1641-3466
Pojawia się w:
Zeszyty Naukowe. Organizacja i Zarządzanie / Politechnika Śląska
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Application of pixantrone in a III line of treatment as a bridge therapy to allotransplantation of stem cells
Autorzy:
Kwiatkowska-Pamuła, Anna
Janeczek, Aleksandra
Giebel, Sebastian
Powiązania:
https://bibliotekanauki.pl/articles/1035647.pdf
Data publikacji:
2020-06-30
Wydawca:
Medical Education
Tematy:
DLBCL lymphoma
allo-HSCT
cardiotoxicity
chemotherapy
pixantrone
Opis:
Diffuse large B-cell lymphomas are the most common group among all lymphomas. Despite the effectiveness of the I line therapy in 10–40% of patients, the possibility of relapse should be taken into account. The anthracycline antibiotics used in the II line therapy carry a high risk of cardiac complications. In patients with refractory or recurrent disease, emergency treatment is used, aiming for the transplantation of hematopoietic cells. If the II line therapy fails, the prognosis is bad. A new chance for patients with refractory or recurrent B-cell lymphoma is pixantrone dimaleate, a drug structurally related to anthracyclines with a significantly lower cardiotoxic potential. The paper presents a case of a 65-year-old patient with relapsing DLBCL lymphoma, after two treatment lines: R-CHOP and R-DHAP, and after autologous transplantation of stem cells, in which the use of pixantrone in the treatment of recurrence allowed to achieve remission and prepare the patient for the allo-HSCT procedure.
Źródło:
OncoReview; 2020, 10, 2; 57-61
2450-6125
Pojawia się w:
OncoReview
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Manufacturing and characterization of gellan gum – zinc oxide composites as potential biomaterials for wound treatment
Autorzy:
Macyk, Alicja
Kusibab, Anna
Pamuła, Elżbieta
Powiązania:
https://bibliotekanauki.pl/articles/27324040.pdf
Data publikacji:
2023
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
gellan gum
zinc oxide nanoparticles
zinc oxide
microparticles
wound healing
L929 fibroblasts
cynk
fibroblasty
biomateriały
Opis:
This study aimed to produce gellan gum-based hydrogels with the addition of zinc oxide as a potential dressing material. Hydrogels with ZnO concentrations of 0.01%, 0.02% and 0.04% were prepared, micrometric and nanometric ZnO particles were used, and a CaCl2 crosslinker was added to one part of the samples. All samples (14 types) produced by the freeze drying method were characterized with high swelling properties (>2000%), what is important to ensure the absorption of exudates from wounds. Samples with ZnO particles cross-linked with CaCl2 lost less mass after incubation in aqueous media and were characterized by better dimensional stability than those without crosslinking. The pH of the extracts of the samples containing ZnO particles was more neutral (pH 7.0-7.6) than that of the control gellan gum samples (pH of 5.5-6.1). The zinc release from cross-linked samples was twice as high for those containing nanometric particles than for micrometric particles (1.94 ± 0.04 mg/l and 0.93 ± 0.02, respectively). Relatively large amounts of released zinc species in the case of samples containing ZnO nanoparticles are promising in the context of the antibacterial properties and treatment of infected wounds. A lower amount of zinc released from samples with ZnO microparticles could be sufficient to prevent the development of the infection. Furthermore, both materials show satisfactory cytocompatibility with L929 fibroblasts, as shown by Alamar blue and live/dead viability tests, making them prospective candidates for wound healing
Źródło:
Engineering of Biomaterials; 2023, 26, 168; 2--8
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Curcumin delivery systems as dressing components for the treatment of diabetic foot ulcers: test on macrophages polarization
Autorzy:
Wójcik, Karolina
Kusibab, Anna
Sousa, Ana Beatriz
Barbosa, Judite Novais
Pamuła, Elżbieta
Powiązania:
https://bibliotekanauki.pl/articles/27324039.pdf
Data publikacji:
2023
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Tematy:
curcumin
immunomodulation
inflammation
macrophage polarization
polymeric microparticles
wound healing
makrofagi
polaryzacja
biomateriały
Opis:
The natural wound healing process consists of four basic phases: homeostasis, inflammation, proliferation, and remodelling. Macrophages play an important role in the body’s response to biomaterials, as they are modulators of the wound healing process and can polarize into different phenotypes capable of inducing both deleterious and beneficial effects on tissue repair. Curcumin (CU) is known for its anti-inflammatory properties and has the potential to treat diabetic foot ulcers, but it should be delivered to wounds in a controlled manner. In this study, the encapsulation of curcumin in polymeric microparticles based on poly(sebacic anhydride) (PSA) was developed using an emulsification method. PSA-based microparticles containing different concentrations of CU were obtained: 0% weight (wt). CU (unloaded microparticles), 5, 10, and 20 wt% CU. CU encapsulation efficiency and loading were determined using a fluorescence-based calibration curve method and semi-quantitative Fourier-transform infrared spectroscopy (FTIR) analysis. The potential cytotoxicity of the obtained biomaterials in contact with primary human macrophages and their susceptibility to polarization from the M1 (pro-inflammatory) phenotype to the M2 (antiinflammatory) phenotype were evaluated. The morphology of cells cultured in contact with polymeric microparticles was evaluated using phalloidin red and 4′,6-diamidino2-phenylindole (DAPI) staining. Macrophage phenotype was assessed using flow cytometry. The obtained biomaterials showed no cytotoxic effect on primary human macrophages. Flow cytometry studies showed enhanced polarization of macrophages into anti-inflammatory M2 phenotype when exposed to microparticles loaded with CU and CU powder as compared to unloaded microparticles
Źródło:
Engineering of Biomaterials; 2023, 26, 168; 15--24
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Synthesis and characterization of novel amphiphilic poly(2- oxazoline)-based copolymers for surface modification of biomaterials
Autorzy:
Tryba, Anna Maria
Kroneková, Zuzana
Mičušík, Matej
Paluszkiewicz, Czesława
Pamuła, Elżbieta
Kronek, Juraj
Powiązania:
https://bibliotekanauki.pl/articles/284353.pdf
Data publikacji:
2019
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Źródło:
Engineering of Biomaterials; 2019, 22, no.153; 87
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Poly(L-lactide-co-glycolide) membranes modified with RGD-poly-(2-oxazoline) for biomedical application
Autorzy:
Tryba, Anna Maria
Krok-Borkowicz, Małgorzata
Piergies, Natalia
Paluszkiewicz, Czesława
Frączyk, Justyna
Kolesińska, Beata
Pamuła, Elżbieta
Powiązania:
https://bibliotekanauki.pl/articles/1844845.pdf
Data publikacji:
2021
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Źródło:
Engineering of Biomaterials; 2021, 24, 163; 44
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Spectroscopy analyses of structure-property correlations in citrate-based elastomeric biomaterials
Autorzy:
Koper, Filip
Świergosz, Tomasz
Żaba, Anna
Flis, Agata
Trávníčková, Martina
Bačáková, Lucie
Pamuła, Elżbieta
Bogdał, Dariusz
Kasprzyk, Wiktor
Powiązania:
https://bibliotekanauki.pl/articles/1844713.pdf
Data publikacji:
2021
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Źródło:
Engineering of Biomaterials; 2021, 24, 163; 94
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Structure-property correlation studies of cross-linked citric acid-based elastomers
Autorzy:
Koper, Filip
Świergosz, Tomasz
Żaba, Anna
Flis, Agata
Bogdał, Dariusz
Trávníčková, Martina
Bačáková, Lucie
Pamuła, Elżbieta
Kasprzyk, Wiktor
Powiązania:
https://bibliotekanauki.pl/articles/1844844.pdf
Data publikacji:
2021
Wydawca:
Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie. Polskie Towarzystwo Biominerałów
Źródło:
Engineering of Biomaterials; 2021, 24, 163; 45
1429-7248
Pojawia się w:
Engineering of Biomaterials
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-8 z 8

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