Autor: Płaczkowska, Sylwia - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Discrepancies in occurrence of metabolic disturbances related to gender among young people
Autorzy:: Płaczkowska, Sylwia
Pawlik-Sobecka, Lilla
Kokot, Izabela
Piwowar, Agnieszka
Powiązania:: https://bibliotekanauki.pl/articles/552966.pdf
Data publikacji:: 2017
Wydawca:: Stowarzyszenie Przyjaciół Medycyny Rodzinnej i Lekarzy Rodzinnych
Tematy:: metabolic diseases, metabolic syndrome X, young adult.
Źródło:: Family Medicine & Primary Care Review; 2017, 4; 387-392
1734-3402
Pojawia się w:: Family Medicine & Primary Care Review
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: The impact of dietary nitrates and acrylamide intake on systemic redox status in healthy young adults
Autorzy:: Piwowar, Agnieszka
Żurawska-Płaksej, Ewa
Bizoń, Anna
Sawicka, Ewa
Płaczkowska, Sylwia
Prescha, Anna
Powiązania:: https://bibliotekanauki.pl/articles/23370829.pdf
Data publikacji:: 2023-12-15
Wydawca:: Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:: acrylamide
nitrates
oxidative stress
intake with food
nutritional survey
oxidative/antioxidative balance
Opis:: Objectives The nitrogen-containing xenobiotics, such as nitrates and acrylamide may potentially influence systemic redox status and contribute to the generation of oxidative stress (OS) in the human body, but there is still a lack of studies that would evaluate the various parameters assessing the oxidative-antioxidant balance. The aim of this study was to evaluate the exposure to nitrates and acrylamide derived from daily diet and to analyze the impact of these nitrate-containing xenobiotics on the parameters of systemic redox status in healthy young adults. Material and Methods To assess nitrate and acrylamide intake in the study population, a semi-quantitative food frequency questionnaire was used. Systemic redox status was evaluated by measurement of a panel of biochemical parameters: enzymatic (glutathione S-transferase, glutathione reductase, glutathione peroxidase [GPx]) and non-enzymatic (uric acid, bilirubin and albumin), thiol/disulphide homeostasis parameters (total thiol, native thiol, and disulfide) and oxidative/ antioxidant balance indicators (total antioxidant status, total oxidant status, OS index). Results The average consumption of nitrates and acrylamide in the study population was 1.24 mg/kg b.w./day and 0.23 μg/kg b.w./day, respectively, which is within the normal value range. Of 12 measured parameters, significant differences were revealed for disulfide and total thiol levels, which were increased in the subgroup with the highest daily intake of nitrates compared to the subgroup with the lowest intake; for GPx, which was highest in the subgroup of the lowest daily intake of acrylamide; and for native thiols in the subgroup with the highest daily intake. Conclusions The intake of nitrogen-containing xenobiotics within the range considered as normal does not markedly influence redox state parameters in healthy young adults. Some significant changes were revealed only for thiol/disulphide homeostasis parameters, which may be the first line of antioxidant defense, as well as for GPx activity. Compensative mechanisms in healthy young people are efficient enough to neutralize OS induced by slightly increased exposure to nitrogen-containing xenobiotics delivered with food.
Źródło:: International Journal of Occupational Medicine and Environmental Health; 2023, 36, 6; 773-787
1232-1087
1896-494X
Pojawia się w:: International Journal of Occupational Medicine and Environmental Health
Dostawca treści:: Biblioteka Nauki

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