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    Wyświetlanie 1-8 z 8
    Tytuł:
    Fibromatosis aggressiva of parapharyngeal space – a case report and review of literature.
    Autorzy:
    Piotrowska, Angelika
    Rzepakowska, Anna
    Chęciński, Piotr
    Niemczyk, Kazimierz
    Powiązania:
    https://bibliotekanauki.pl/articles/1400253.pdf
    Data publikacji:
    2017
    Wydawca:
    Index Copernicus International
    Tematy:
    desmoid-type fibromatosis
    parapharyngeal space tumor
    head and neck neoplasms
    Opis:
    Desmoid fibromatosis is defined as a rare fibroblastic proliferation. Although histologically benign, desmoids are locally invasive and associated with a high local recurrence rate. When located in the head and neck region, fibromatosis tends to be more aggressive and associated with significant morbidity, which may be attributed to the proximity of the vital structures. We report a case of 33-year-old woman with aggressive fibromatosis of parapharyngeal space. Complete surgical excision of the lesion was performed and the postoperative period was without complications. The patient remains under careful follow-up and there is no recurrence of the disease.
    Źródło:
    Polski Przegląd Otorynolaryngologiczny; 2017, 6, 2; 10-15
    2084-5308
    2300-7338
    Pojawia się w:
    Polski Przegląd Otorynolaryngologiczny
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Metallic body foreign language - case report
    Autorzy:
    Kuźmińska, Magdalena
    Wężyk, Aleksandra
    Kołodziejczyk, Paulina
    Gotlib, Tomasz
    Chęciński, Piotr
    Niemczyk, Kazimierz
    Powiązania:
    https://bibliotekanauki.pl/articles/1399934.pdf
    Data publikacji:
    2018
    Wydawca:
    Index Copernicus International
    Tematy:
    foreign body
    language
    metallic
    Opis:
    Probably every laryngologist in his career will face off an issue of foreign body removal. It can be problematic especially that foreign body cause the trauma of surrounding tissues or may translocate unpredictably. A space of the middle and lower throat is the most common location. Occasionally it can be located in less obviously place, which force the laryngologist to prevent more viligant diagnostic. A foreign body pounded within soft tissue of the oral cavity is the example. A case report of a metallic foreign body inherent in the tongue for more than six weeks before the final treatment is presented.
    Źródło:
    Polski Przegląd Otorynolaryngologiczny; 2018, 7, 2; 41-44
    2084-5308
    2300-7338
    Pojawia się w:
    Polski Przegląd Otorynolaryngologiczny
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Bone conduction stimulation of the otic capsule: a finite element model of the temporal bone
    Autorzy:
    Borkowski, Paweł
    Marek, Piotr
    Niemczyk, Kazimierz
    Lachowska, Magdalena
    Kwacz, Monika
    Wysocki, Jarosław
    Powiązania:
    https://bibliotekanauki.pl/articles/306896.pdf
    Data publikacji:
    2019
    Wydawca:
    Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
    Tematy:
    FEM
    kośc skroniowa
    ucho wewnętrzne
    bone conduction
    finite element analysis
    temporal bone
    otic capsule
    cochlea
    inner ear
    Opis:
    Bone conduction stimulation applied on the otic capsule may be used in a conductive hearing loss treatment as an alternative to the bone conduction implants in clinical practice. A finite element study was used to evaluate the force amplitude and direction needed for the stimulation. Methods: A finite element model of a female temporal bone with a precisely reconstructed cochlea was subjected to a harmonic analysis assuming two types of stimulation. At first, the displacement amplitude in the form of air conduction stimulation was applied on the stapes footplate. Then the force amplitude was applied on the otic capsule in the form of bone conduction stimulation. The two force directions were considered: 1) the primary direction, when a typical opening is performed during mastoidectomy, and was coincident with the axis of an imaginary cone, inscribed in the opening, and 2) the direction perpendicular to the stapes footplate. The force amplitude was set so that the response from the cochlea corresponded to the result of air conduction stimulation applied on the stapes footplate. Results: The amplitude and phase of vibration and the volume displacement on the round window membrane were considered as well as vibrations of the basilar membrane, spiral lamina, and promontory. Conclusions: The cochlear response was comparable for the two types of stimulation. The efficiency of bone conduction stimulation depended on the force direction. For the primary direction, the force was a few times smaller than for the direction perpendicular to the stapes footplate.
    Źródło:
    Acta of Bioengineering and Biomechanics; 2019, 21, 3; 75-86
    1509-409X
    2450-6303
    Pojawia się w:
    Acta of Bioengineering and Biomechanics
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Rare proliferative and inflammatory pathologies localized in the temporal bone – a review of the literature
    Autorzy:
    Roszkowski, Adam
    Witkowska, Alicja
    Baranek, Piotr
    Rzepakowska, Anna
    Wnuk, Emilia
    Niemczyk, Kazimierz
    Powiązania:
    https://bibliotekanauki.pl/articles/1399647.pdf
    Data publikacji:
    2019
    Wydawca:
    Index Copernicus International
    Tematy:
    fibrous dysplasia
    inflammatory pseudotumor
    osteoradionecrosis
    proliferative-inflammatory pathologies
    skull base
    temporal bone
    Opis:
    Introduction: Proliferative-inflammatory pathologies may occupy the temporal bone, resulting in: hearing loss, vestibular dysfunction, and neuropathies from cranial nerve compression. Although their occurrence is episodic, the appropriate diagnostic procedure is extremely important to achieve expected therapeutic effect. Aim: The aim of study was characterization of selected proliferative-inflammatory pathologies that may occupy the temporal bone: fibrous dysplasia, inflammatory pseudotumor, osteoradionecrosis, and presentation of diagnostic methods for the differentiation of these diseases as well as discussion on appropriate therapeutic options. Fibrous dysplasia (FD) is a slowly progressive, benign bone disorder of unknown etiology characterized by abnormal proliferation of fibrous tissue. Inflammatory pseudotumor (IPT) is a rare, non-malignant inflammatory process of unknown etiology, characterized by connective tissue proliferation and infiltration of inflammatory cells. Osteoradionecrosis of the temporal bone (TB-ORN) is a rare but potentially fatal complication of radiotherapy for head and neck cancer. Results: Due to the similarity of symptoms with typical inflammatory conditions of middle ear (pain, otorrhea, hearing loss), selected disorders may be a dilemma regarding the diagnosis and proper further treatment. The clinical examination is mandatory, however radiological imaging may demonstrate the presence of specific changes and direct the diagnosis. The computed tomography (CT) of fibrous dysplasia shows the abnormal organization of the bone structure. Magnetic resonance (MRI), as the most sensitive for inflammatory pseudotumors, visualizes inflammatory infiltration in soft tissues. The CT of temporal bone identifies the erosion in the course of osteoradionecrosis. However in all cases the final diagnosis may be establish using histopathological examination and after exclusion of the neoplastic process.
    Źródło:
    Polski Przegląd Otorynolaryngologiczny; 2019, 8, 3; 8-13
    2084-5308
    2300-7338
    Pojawia się w:
    Polski Przegląd Otorynolaryngologiczny
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    100 years of the Department of Otolaryngology, Head & Neck Surgery at the Medical University of Warsaw
    Autorzy:
    Niemczyk, Kazimierz
    Bruzgielewicz, Antoni
    Osuch Wójcikiewicz, Ewa
    Chęciński, Piotr
    Pierchała, Katarzyna
    Bartoszewicz, Robert
    Powiązania:
    https://bibliotekanauki.pl/articles/1399277.pdf
    Data publikacji:
    2020
    Wydawca:
    Index Copernicus International
    Tematy:
    Chair and Clinic of Otorhinolaryngology
    clinic achievements
    Development of Academic Otorhinolaryngology
    Opis:
    January 15, 2021 marks a hundred years from the establishment of the Clinic of Otorhinolaryngology, Head and Neck Surgery at the Medical University of Warsaw. The authors representing the oldest generations of the current Team present the history of the Clinic from the foundation until the present day. The main achievements throughout history and selected activities of the currently working Team are described.
    Źródło:
    Polski Przegląd Otorynolaryngologiczny; 2020, 9, 4; 1-10
    2084-5308
    2300-7338
    Pojawia się w:
    Polski Przegląd Otorynolaryngologiczny
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Basal cell carcinoma of the facial skin penetrating to the orbit – case report
    Autorzy:
    Czesak, Małgorzata
    Chęciński, Piotr
    Osuch-Wójcikiewicz, Ewa
    Bruzgielewicz, Antoni
    Sokołowski, Jacek
    Niemczyk, Kazimierz
    Powiązania:
    https://bibliotekanauki.pl/articles/1400278.pdf
    Data publikacji:
    2017
    Wydawca:
    Index Copernicus International
    Tematy:
    skin cancer
    basal cell carcinoma
    orbit
    Opis:
    Basal cell carcinoma (BCC) is the most frequent malignant neoplasm of the skin. In this report we present a case of a 59-year-old patient, who had noticed for five years gradually growing tumor of the facial skin. MR scans revealed pathological lesion in the left orbit. The patient required partial resection of the nose, orbital exenteration with anterolateral thigh free flap reconstruction. The authors present diagnostic problems and methods of treatment BCC.
    Źródło:
    Polski Przegląd Otorynolaryngologiczny; 2017, 6, 2; 64-69
    2084-5308
    2300-7338
    Pojawia się w:
    Polski Przegląd Otorynolaryngologiczny
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Salvage surgery of hypopharyngeal cancer as a second malignancy post radiotherapy and the possibility of digestive track reconstruction – study of three cases and the literature review
    Autorzy:
    Rzepakowska, Anna
    Jasińska, Agnieszka
    Wolniewicz, Maria
    Baranek, Piotr
    Osuch-Wójcikiewicz, Ewa
    Bruzgielewicz, Antoni
    Niemczyk, Kazimierz
    Powiązania:
    https://bibliotekanauki.pl/articles/1399615.pdf
    Data publikacji:
    2019
    Wydawca:
    Index Copernicus International
    Tematy:
    head and neck cancer
    second primary cancer
    hypopharyngeal cancer
    salvage surgery
    digestive tract reconstruction
    radial forearm free flap
    free autologous jejunal flap
    Opis:
    Patients with head and neck cancers have an increased risk of second malignant neoplasm occurrence (25% in long-term follow-up, 4% yearly). Most patients with a primary tumor can be treated with organ-preserving strategies including radiotherapy (RT) or chemoradiotherapy (CRT). Very often after radical surgical excision there are indications for adjuvant radiotherapy. However, if recurrence or second malignancy will develop after definitive primary RT, there are limitation to use therapeutic dose of radiation again for the same area. Salvage surgery is regarded as the only curative option in those cases. In our study we analysed 3 patients, who presented with head and neck second cancer in the area of hypopharynx, within 10-25 years after primary radiotherapy due to oropharyngeal and laryngeal cancer. A total pharyngectomy with larynx preservation and bilateral neck dissection were performed in the first case and the radial forearm free flap (RFFF) was used for reconstruction of the pharynx. Second patient, due to perilaryngeal invasion in radiological images, underwent total pharyngolaryngectomy with selective bilateral cervical lymph nodes dissection and digestive track was restored also with RFFF. The third patient had previously undergone laryngectomy and after total pharyngectomy the free autologous jejunal flap (FAJF) was used for reconstruction. The main goal of reconstruction after salvage surgery due to hypopharyngeal cancer is to reconstruct the digestive tract. The other important aspect is to optimize the anatomy for voice rehabilitation and swallowing. Unfortunately, radiation and chemotherapy impair wound healing, which indicates increased risk of postoperative complications and makes salvage surgery results unpredictable.
    Źródło:
    Polski Przegląd Otorynolaryngologiczny; 2019, 8, 1; 33-39
    2084-5308
    2300-7338
    Pojawia się w:
    Polski Przegląd Otorynolaryngologiczny
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Partial characterization of human choriocarcinoma cell line JAR cells in regard to oxidative stress.
    Autorzy:
    Hallmann, Anna
    Klimek, Jerzy
    Masaoka, Makoto
    Kamiński, Marcin
    Kędzior, Jakub
    Majczak, Anna
    Niemczyk, Edyta
    Woźniak, Michał
    Trzonkowski, Piotr
    Wakabayashi, Takashi
    Powiązania:
    https://bibliotekanauki.pl/articles/1041517.pdf
    Data publikacji:
    2004
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    menadione
    flow cytometry
    JAR cells
    placenta
    H2O2
    oxidative stress
    Opis:
    Characterization of free radical-induced cell injury processes of placenta cells is of vital importance for clinical medicine for the maintenance of intrauterine fetal life. The present study has analyzed cell injury processes in cells of the choriocarcinoma cell line JAR treated with menadione, an anticancer drug, and Hg2O2 in comparison to osteosarcoma 143B cells using electron microscopic and flow cytometric techniques. Flow cytometry on JAR cells exposed to 100 μM menadione and double-stained with Annexin V and propidium iodide (PI) detected apoptotic cells reaching the maximum after 4 h of incubation with a rapid decrease thereafter. Viable cells became decreased to 46% of the control after 2 h of incubation, reaching 5% after 4 h. Cells stainable with both Annexin V and PI began to increase distinctly after 2 h of incubation, reaching 55% after 4 h. Electron microscopy showed that cells stainable with both dyes specified above had condensed nuclei and swollen cytoplasm, suggesting that they were undergoing a switch of the cell death mode from apoptosis to necrosis. On the other hand, 90% of 143B cells remained intact after 4 h of menadione treatment although the intracellular levels of superoxide were always higher than those of JAR cells treated with the drug. In contrast, JAR cells were more resistant than 143B cells to H2O2-induced cytotoxicity. These results may suggest that cytotoxicity of menadione cannot be explained simply by oxygen free radicals generated from the drug. The resistance of JAR cells to oxygen free radical-induced cytotoxicity may be advantageous for intrauterine fetal life.
    Źródło:
    Acta Biochimica Polonica; 2004, 51, 4; 1023-1038
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-8 z 8

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