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Wyszukujesz frazę "Michalak, Piotr." wg kryterium: Autor

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    Wyświetlanie 1-15 z 15
    Tytuł:
    Thermal - electrical analogy in dynamic simulations of buildings: comparison of four numerical solution methods
    Autorzy:
    Michalak, Piotr
    Powiązania:
    https://bibliotekanauki.pl/articles/1819185.pdf
    Data publikacji:
    2020
    Wydawca:
    Politechnika Koszalińska. Wydawnictwo Uczelniane
    Tematy:
    thermal-electrical analogy
    RC network
    lumped capacitance
    BESTEST
    Euler method
    Heun's method
    analogia termiczna
    analogia elektryczna
    metoda Eulera
    Opis:
    The lumped capacitance method is widely used in dynamic modelling of buildings. Models differ in complexity, solution methods and ability to simulate transient behaviour of described objects. The paper presents a mathematical description of a simple 1R1C thermal network model of a building zone. Four numerical methods were applied to solve differential equation describing its dynamics. For validation purposes two test cases (600 and 900) from the BESTEST procedure were used. In both cases detailed results were given. Better ability of the simulation model to reproduce transient behaviour of the modelled buildings was noticed in case of the lightweight object (case 600). Annual heating and cooling demand was within the reference range for heavyweight one (case 900). The kind of the computation method had no significant effect on simulation results.
    Źródło:
    Journal of Mechanical and Energy Engineering; 2020, 4, 2; 179--188
    2544-0780
    2544-1671
    Pojawia się w:
    Journal of Mechanical and Energy Engineering
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Modelling of global solar irradiance on sloped surfaces in climatic conditions of Kraków
    Autorzy:
    Michalak, Piotr
    Powiązania:
    https://bibliotekanauki.pl/articles/2064387.pdf
    Data publikacji:
    2019
    Wydawca:
    STE GROUP
    Tematy:
    diffuse irradiance
    anisotropic model
    sloped surface
    typical meteorological year
    EN-ISO 52010-1
    model anizotropowy
    typowy rok meteorologiczny
    natężenie promieniowania słonecznego
    Opis:
    The paper presents calculations of global solar irradiance on inclined surfaces of any orientation in the hourly time step. For computational purposes there were used the data from typical meteorological years (TMY) available in a form of text files on the website of the Ministry of Infrastructure and Development. Hourly solar global horizontal irradiance from measurements from the file for Kraków was used as input for five anisotropic models (Hay, Muneer, Reindl, Perez and Perez according to the new PN-EN ISO 52010-1 standard). Direct normal and diffuse horizontal and then global irradiances were calculated. To illustrate the effects of using different models, for the exemplary residential building, monthly solar heat gains and heating demand was determined according to the monthly method of PN-EN ISO 13790. In comparison to the solar data from the TMY, an average decrease in the value of solar gains amounted 37%, what resulted in an increase in the calculated heat demand of the building by 10%. This is very important since this change takes place without any modernisation works.
    Źródło:
    New Trends in Production Engineering; 2019, 2, 1; 505--514
    2545-2843
    Pojawia się w:
    New Trends in Production Engineering
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Application of artificial neural networks in predicting voter turnout based on the analysis of demographic data
    Autorzy:
    Michalak, Piotr
    Powiązania:
    https://bibliotekanauki.pl/articles/92572.pdf
    Data publikacji:
    2019
    Wydawca:
    Oddział Kartograficzny Polskiego Towarzystwa Geograficznego
    Tematy:
    artificial neural networks
    voter turnout
    machine learning
    cartographic research method
    Opis:
    The author presents the results of research on the use of artificial neural networks in predicting voter turnout. He describes the principles of operation of artificial neural networks, as well as detailed results of two machine learning methods used to predict voter turnout. The research resulted in creation of a functional model that allows for prediction of voter turnout results with a considerable degree of accuracy. The entire research process was carried out using the cartographic research method.
    Źródło:
    Polish Cartographical Review; 2019, 51, 3; 109-116
    2450-6974
    Pojawia się w:
    Polish Cartographical Review
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Ventilation heat loss in a multifamily building under varying air density
    Autorzy:
    Michalak, Piotr
    Powiązania:
    https://bibliotekanauki.pl/articles/95344.pdf
    Data publikacji:
    2020
    Wydawca:
    Politechnika Koszalińska. Wydawnictwo Uczelniane
    Tematy:
    air density
    heat capacity
    dry air
    volumetric heat capacity
    ventilation heat loss
    EN ISO 13790
    monthly method
    gęstość powietrza
    pojemność cieplna
    suche powietrze
    objętościowa pojemność cieplna
    wentylacyjna strata ciepła
    Opis:
    Standards related to calculation methods used in building energy performance simulation tools usually impose constant volumetric heat capacity of air. However, this simplification may result in errors if the actual conditions differ from the assumptions made. The paper presents the problem of dry air density and specific heat capacity variation and their influence on calculated energy use for space heating in a multifamily building. The monthly calculation method of PN-EN ISO 13790 was used. Simulations were performed in five cities, each in one climatic zone according to PN-EN 12831. Variation of the air density caused by air temperature and elevation resulted in differences in calculated heating demand from -4.5% to 4.5% in relation to that at constant volumetric heat capacity assumed in PN-EN ISO 13790.
    Źródło:
    Journal of Mechanical and Energy Engineering; 2020, 4, 1; 97-102
    2544-0780
    2544-1671
    Pojawia się w:
    Journal of Mechanical and Energy Engineering
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Temperature efficiency of heat exchangers in air handling units
    Autorzy:
    Michalak, Piotr
    Grygierczyk, Stanisław
    Powiązania:
    https://bibliotekanauki.pl/articles/95368.pdf
    Data publikacji:
    2019
    Wydawca:
    Politechnika Koszalińska. Wydawnictwo Uczelniane
    Tematy:
    ventilation
    heat recovery
    rotary heat exchanger
    cross-flow heat exchanger
    temperature efficiency
    PN-EN 308
    wentylacja
    odzysk ciepła
    obrotowy wymiennik ciepła
    krzyżowy wymiennik ciepła
    sprawność temperaturowa
    Opis:
    In order to reduce ventilation heat loss and improve energy efficiency of low-energy buildings air-handling units (AHUs) with heat recovery are used. The article presents results of surveys performed in a passive building located in Katowice concerning the temperature efficiency of heat and cold recovery of two selected AHUs, with different heat exchangers. For this purpose the measurement data from the Building Management System (BMS) for the period 1.08.2015-31.07.2016 were used. The first unit was equipped with a rotary heat exchanger. Its average annual temperature efficiency of heat recovery was 47.2% annually. The efficiency of cold recovery amounted 52.9% on average for the warm half year. The second unit had a cross-flow exchanger. The average annual temperature efficiency of heat recovery in this device was 80.1%. The efficiency of cold recovery amounted 57.2% on average for the warm half year. Additional remarks concerning the temperature measurement in analysed units were also given.
    Źródło:
    Journal of Mechanical and Energy Engineering; 2019, 3, 3; 267-272
    2544-0780
    2544-1671
    Pojawia się w:
    Journal of Mechanical and Energy Engineering
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Conception and realization of 19d locomotive modernization
    Koncepcja i realizacja modernizacji lokomotywy 19d
    Autorzy:
    Michalak, Piotr
    Jakuszko, Wojciech
    Powiązania:
    https://bibliotekanauki.pl/articles/33770822.pdf
    Data publikacji:
    2017
    Wydawca:
    Sieć Badawcza Łukasiewicz - Poznański Instytut Technologiczny
    Tematy:
    locomotive 19d
    modernization
    concept
    implementation
    lokomotywa 19d
    modernizacja
    koncepcja
    realizacja
    Opis:
    The article presents the main stages of the process of 19D locomotive modernization. The assumptions of locomotive design, stages of conception, realization of modernization, and the final stage of the locomotive are described. The modernization of locomotive was as a part of the realized project of Applied Research Program 3 No PBS3/B6/33/2015 titled: „Platform of modernized combustion 6-axle locomotives meeting the requirements of European Union with using locomotives operated in the country” carried out by the Rail Vehicles Institute ‘TABOR” in Poznań and the Rail Vehicles PESA Bydgoszcz S.A.
    W artykule przedstawiono główne etapy procesu realizacji modernizacji lokomotywy 19D. Opisano założenia projektu lokomotywy, etapy koncepcji, realizacji modernizacji, aż do końcowego etapu powstania lokomotywy. Modernizacja lokomotywy powstała w ramach realizowanego projektu Programu Badań Stosowanych 3 nr PBS3/B6/33/2015 pt.: „Platforma zmodernizowanych spalinowych lokomotyw 6-osiowych spełniających wymagania Unii Europejskiej z wykorzystaniem lokomotyw eksploatowanych w kraju” wykonywanego przez Instytut Pojazdów Szynowych TABOR w Poznaniu i Pojazdy Szynowe PESA Bydgoszcz S.A.
    Źródło:
    Rail Vehicles/Pojazdy Szynowe; 2017, Nr 4; 57-68
    0138-0370
    2719-9630
    Pojawia się w:
    Rail Vehicles/Pojazdy Szynowe
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Ageism: A Problem of the Twenty First Century
    Ageizm: problem XXI wieku
    Autorzy:
    Michalak, Piotr
    Zarzecki, Andrzej
    Zarzecka, Joanna
    Powiązania:
    https://bibliotekanauki.pl/articles/22446485.pdf
    Data publikacji:
    2021
    Wydawca:
    Stowarzyszenie Absolwentów i Przyjaciół Wydziału Prawa Katolickiego Uniwersytetu Lubelskiego
    Tematy:
    ageism
    discrimination
    medicine
    dentistry
    COVID-19
    ageizm
    dyskryminacja
    medycyna
    stomatologia
    Opis:
    The ageing of society is a global process which is gaining strength. The quality of ageing is an essential parameter of this process. It has been predicted that the percentage of elderly individuals will double during the period 2015-2050. The aim of the present paper was to analyse the literature on discriminatory behaviour due to age, or so-called ageism, with particular emphasis on behaviour within the area of healthcare, including that of dentists. Ageism may constitute an important factor in the health and well-being of elderly people, one which should be considered in the design of strategies to support healthier and happier ageing. A survey of the Polish population showed that 26% of participants aged 65 and over considered that their peers are being discriminated against, whereas 8% had personally witnessed discrimination. It has been emphasised that aversion to the elderly and discrimination against them in medical facilities is observed more frequently in situations involving time pressure and shortage of medical personnel. More and more frequently, elderly people retain their natural teeth; accordingly, there is a growing demand for trained dentists to provide comprehensive care for elderly patients. Nevertheless, it has been indicated that mere improvement of levels of knowledge about the ageing process does not change attitudes towards elderly patients. Following analysis of the relevant literature, it should be noted that the volume of research on ageism conducted outside the US is negligible. Research related to this subject in the field of dentistry is most often limited to students’ attitudes. The current COVID-19 pandemic has highlighted inappropriate behaviours characterised by ageism.
    Starzenie się społeczeństwa jest procesem globalnym i przybierającym na sile, a jakość starzenia się jest istotnym parametrem tego procesu. Prognozuje się, że w latach 2015-2050 dojdzie do podwojenia odsetka ludzi w wieku starszym. Celem pracy była analiza piśmiennictwa dotycząca zachowań dyskryminacyjnych ze względu na wiek tzw. ageizm, ze szczególnym uwzględnieniem zachowań w obrębie ochrony zdrowia, w tym również lekarzy dentystów. Ageizm może być ważnym czynnikiem wpływającym na zdrowie i samopoczucie osób starszych, co powinno być brane pod uwagę przy opracowywaniu strategii wspierania zdrowszego i szczęśliwszego starzenia się. W badaniu ankietowym populacji Polskiej wykazano, że 26% uczestników powyżej 65. roku życia uważa grupę swoich rówieśników za dyskryminowaną, a 8% było świadkami dyskryminacji. Podkreśla się, że niechęć do ludzi starszych i ich dyskryminacja w placówkach medycznych jest częściej obserwowana w sytuacjach presji czasowej i niedoboru personelu medycznego. Starsi ludzie coraz częściej zachowują naturalne uzębienie, w związku z tym rośnie zapotrzebowanie na przeszkolonych lekarzy zajmujących się kompleksową opieką nad pacjentami w starszym wieku. Pomimo to wskazuje się, że sama poprawa wiedzy na temat procesu starzenia nie zmienia postawy wobec pacjentów seniorów. Po analizie piśmiennictwa należy zauważyć znikomą ilość badań poświęconych tematyce ageizmu prowadzonych poza USA. Badania prowadzone w dziedzinie stomatologii odnoszące się do tej tematyki najczęściej ograniczane są do badania postaw studentów. Obecny czas pandemii COVID-19 uwypuklił nieprawidłowe zachowania obarczone ageizmem.
    Źródło:
    Biuletyn Stowarzyszenia Absolwentów i Przyjaciół Wydziału Prawa Katolickiego Uniwersytetu Lubelskiego; 2021, 16, 18 (2); 193-207
    2719-3128
    2719-7336
    Pojawia się w:
    Biuletyn Stowarzyszenia Absolwentów i Przyjaciół Wydziału Prawa Katolickiego Uniwersytetu Lubelskiego
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Possibility to use a dual-drive locomotive type 111DE for passenger transport in the territory of Poland
    Autorzy:
    Michalak, Piotr
    Urbański, Patryk
    Podziński, Mateusz
    Dobrowolski, Piotr
    Powiązania:
    https://bibliotekanauki.pl/articles/38955717.pdf
    Data publikacji:
    2023
    Wydawca:
    Politechnika Warszawska, Wydział Transportu
    Tematy:
    passenger transport
    dual-drive locomotive
    rail transport
    transport pasażerów
    lokomotywa z podwójnym napędem
    transport kolejowy
    Opis:
    The vast majority of passenger rail transport in Poland is carried out by vehicles powered by electric traction. In case when a train needs to pass through a non-electrified section of the line, it is necessary to use an electric traction-independent vehicle, which, translated into the current situation, means using a vehicle with an internal combustion engine. The authors propose using a dual-drive 111DE locomotive for passenger rail transport, which can move on electrified and non-electrified railway lines. The article also presents data on the railway infrastructure and statistics on passenger rail transport in Poland. Considerations and justification for the use of a dual-drive vehicle are presented.
    Źródło:
    WUT Journal of Transportation Engineering; 2023, 136; 35-47
    1230-9265
    Pojawia się w:
    WUT Journal of Transportation Engineering
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The selection of the engine unit - main engine generator during the modernization of the 19D/TEM2 locomotive
    Autorzy:
    Michalak, Piotr
    Merkisz, Jerzy
    Stawecki, Włodzimierz
    Andrzejewski, Maciej
    Daszkiewicz, Paweł
    Powiązania:
    https://bibliotekanauki.pl/articles/2097461.pdf
    Data publikacji:
    2020
    Wydawca:
    Polskie Towarzystwo Naukowe Silników Spalinowych
    Tematy:
    railway
    diesel locomotive
    modernization
    CFD simulation
    exhaust emission
    kolej
    lokomotywa spalinowa
    modernizacja
    symulacja CFD
    emisja spalin
    Opis:
    The paper aims to present a generating set selection methodology for a modernized diesel locomotive. An analysis of the number of rolling stock, with particular emphasis on the number of diesel locomotives owned by national carriers was performed. Based on the popularity of the locomotives operated on Polish railways, the TEM2 locomotive was chosen to be the base reference for the modernized 19D locomotive described in the paper. The scope of the locomotive's modernization was described. Modernization included: replacement of the internal combustion engine, replacement of the generator set, installation of a new braking system with a pneumatic board and air preparation and treatment system, application of a modern control and diagnostics system with anti-slip system at start-up and braking, and the installation of railway traffic safety devices.
    Źródło:
    Combustion Engines; 2020, 59, 3; 38--46
    2300-9896
    2658-1442
    Pojawia się w:
    Combustion Engines
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Color vision assessment following cataract surgery using anomaloscope
    Autorzy:
    Zabel, Jacek
    Michalak, Krzysztof Piotr
    Olszewski, Jan
    Koszałkowski, Maciej
    Przekoracka-Krawczyk, Anna
    Powiązania:
    https://bibliotekanauki.pl/articles/2046657.pdf
    Data publikacji:
    2021-12-27
    Wydawca:
    Medical Education
    Tematy:
    cataract
    color vision deficits
    anomaloscope
    Moreland test
    Ray leigh test
    Opis:
    Aim: To evaluate the impact of cataract on color vision detection using an anomaloscope. Methods: 12 patients aged 64–82 years with history of cataract surgery in one eye and mature cataracts in the other eye were examined for color vision using the Rayleigh and the Moreland anomaloscope tests. Results: Different patterns of blue and green color vision deterioration have been observed in the eye with cataract as compared to the IOL eye. A decrease in M1 to approximately 1 (the minimum of the Moreland test scale) was observed in 5 out of 12 participants, whereas an increase in M2 to 99 (the maximum of the Moreland test scale) was observed in 6 out of 12 subjects. R1 found in the Rayleigh test was significantly lower in the cataract eyes as compared to the IOL eyes (38.9 ± 2.3 vs. 43.4 ± 1.6; p < 0.001). Conclusions: It has been shown that cataract causes a decrease in color sensitivity, especially affecting green and blue colors. Following IOL implantation, the previously deteriorated vision of green and blue was clearly improved. The most valuable parameters of the anomaloscope test, which enable to determine cataract severity, were M1, M2 and R1.
    Źródło:
    OphthaTherapy; 2021, 8, 4; 265-273
    2353-7175
    2543-9987
    Pojawia się w:
    OphthaTherapy
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Protection of valuable areas of local cultural heritage in sustainable development. Cultural parks in the Lodz Region
    Autorzy:
    Boryczka, Ewa M.
    Michalak, Justyna
    Rzeńca, Piotr
    Powiązania:
    https://bibliotekanauki.pl/articles/95968.pdf
    Data publikacji:
    2019
    Wydawca:
    Fundacja Ekonomistów Środowiska i Zasobów Naturalnych
    Tematy:
    dziedzictwo kulturowe
    park kulturowy
    kompleksowa ochrona
    krajobraz kulturowy
    rozwój zrównoważony
    cultural heritage
    cultural park
    comprehensive protection
    cultural landscape
    sustainable development
    Opis:
    Cultural park is one of the forms, in which valuable areas and historical establishments are protected under the Polish law. Protection covers “space” in its entirety with elements of wild nature and man-made structures. Such spaces have been shaped by the history of human interventions into a unique and original cultural landscape, a complex spatial structure consisting of: passages (rivers, channels, roads, and borders), plains (meadows, fields, water reservoirs, and forests), and objects (natural objects and monuments). They ensure sustainability of development processes. In circumstances created by globalisation, investment pressure, and seeking short-term benefits, comprehensive protection of valuable cultural areas acquires special importance from the point of view of sustainable growth. The paper aims to identify valuable areas of local cultural heritage in the context of sustainable development on the example of cultural parks established in the Lodz voivodeship.
    Źródło:
    Ekonomia i Środowisko; 2019, 1; 225-240
    0867-8898
    Pojawia się w:
    Ekonomia i Środowisko
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Purine metabolism in the light of aerobic and anaerobic capacity of female boxers
    Autorzy:
    Domaszewska, Katarzyna
    Szewczyk, Piotr
    Kryściak, Jakub
    Michalak, Edyta
    Podgórski, Tomasz
    Powiązania:
    https://bibliotekanauki.pl/articles/1030895.pdf
    Data publikacji:
    2020
    Wydawca:
    Uniwersytet Szczeciński. Wydawnictwo Naukowe Uniwersytetu Szczecińskiego
    Tematy:
    Acid-Base Balance (ABB)
    Wingate anaerobic test
    anaerobic threshold (AT)
    maximal oxygen uptake
    purine nucleotides
    uric acid
    Opis:
    The aim of the work was to assess the intensity of purine nucleotide degradation during maximum physical exercise. 5 elite female boxers were the subject of the study. Each of them underwent two exercise stress tests in order to evaluate the level of V̊O2peak and the level of anaerobic capacity during a Wingate test. The study involved collecting capillary and venous blood samples at rest and after the exercise test to determine the Acid-Base Balance (ABB), concentration of lactic acid (LA) and purine metabolism nucleotides. The average value of V̊O2peak was 40.92 (SD = 4.087) ml/kg/min, the average anaerobic capacity Ppeak was 7.57 (SD = 0.380) Watt/kg. The workload resulted in significant changes in the level of ABB and LA after both of the exercise stress tests (p < 0.001). Concentrations of hypoxanthine (Hx), xanthine (X) and uric acid (UA) in the blood increased significantly after the Wingate test (p < 0.05). The level of plasma purine nucleotides at rest and after standard exercise may be a useful tool for monitoring the adaptation of energetic processes in different training phases and support the overload diagnosis.
    Źródło:
    Central European Journal of Sport Sciences and Medicine; 2020, 30, 2; 97-106
    2300-9705
    2353-2807
    Pojawia się w:
    Central European Journal of Sport Sciences and Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Septic shock in the course of liver abscess rescued with percutaneous drainage – a literature review and case report
    Autorzy:
    Snarska, Jadwiga
    Michalak, Maciej
    Masiulaniec, Piotr
    Jacyna, Krzysztof
    Zalewski, Artur
    Powiązania:
    https://bibliotekanauki.pl/articles/1393916.pdf
    Data publikacji:
    2016
    Wydawca:
    Index Copernicus International
    Tematy:
    liver abscess
    septic shock
    percutaneous drainage
    Opis:
    This study presented a septic shock occurring with striking speed during the percutaneous drainage of a large abscess of the liver in an 18-year-old female patient after an appendectomy performed 3 months earlier using the laparoscopic method because of its phlegmonous and gangraenosus inflammation. The post-operative course was complicated by increased suppuration in places after removal of the trocars. After including the intravenous antibiotic therapy and under the USG control, the percutaneous drainage of the abscess was performed. While withdrawing the guide of the drainage catheter set, the symptoms of septic shock occurred. The pharmacological treatment was applied with continuation of the antibiotic therapy till a negative result of microbiological tests was obtained and the normalization of life parameters. The patient was not qualified for treatment in the ICU. She was discharged in a generally good condition after 24 days of hospitalization. In the case of this patient, the drain covered with the content of the abscess may have contact with the adjacent tiny blood vessels, which may have contributed to the systemic inflammatory response syndrome that was linked with fast-developing sceptic shock.
    Źródło:
    Polish Journal of Surgery; 2016, 88, 5; 496-503
    0032-373X
    2299-2847
    Pojawia się w:
    Polish Journal of Surgery
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Factors determining the quality of life in patients undergoing radical surgery due to malignant tumors of the rectum
    Autorzy:
    Błaszkowski, Tomasz
    Kładny, Józef
    Al-Amawi, Tariq
    Kaczmarek, Krystian
    Kwietniak, Marcin
    Wojtasik, Piotr
    Halczak, Mirosław
    Michalak, Tomasz
    Jezierski, Karol
    Chmialak, Mariusz
    Powiązania:
    https://bibliotekanauki.pl/articles/1391544.pdf
    Data publikacji:
    2021
    Wydawca:
    Index Copernicus International
    Tematy:
    Rectal cancer
    Quality of life
    Colostomy
    Radiotherapy
    Opis:
    Introduction: Rectal cancer is one of the most common malignancies in developed countries. However, despite the increasingly better preoperative diagnostics, adaptation of surgical techniques to the location and advancement of the tumor, the combination of surgical treatment with neoadjuvant therapy and adjuvant treatment, standardized control tests, Poland still has not obtained satisfactory results regarding long-term survival. In addition, the effects of the therapy often differ significantly from those expected by patients and the doctors treating them. Aim of the study: To evaluate the effects of rectal cancer treatment among patients of the General and Oncological Surgery Clinic of the Pomeranian Medical University in Szczecin. The impact of numerous factors on postoperative quality of life was analyzed. Material and methods: Between 2007 - 2015, 263 radical resection procedures were performed in patients with diagnosed rectal cancer. Retrospectively, based on medical records, a database was created covering a range of clinical data. Information about death dates of some patients was obtained at the Registry Office in Szczecin. A survey supplementing clinical data and standardized quality of life assessment forms (EORTC QLQ - C30 and CR29) were sent to 120 living patients. A telephone conversation was carried out with some patients who did not respond to the surveys. Finally, data from 90 people was collected, which represents 75% of the patients enrolled in the study. Patients quality of life was assessed using EORTC questionnaire evaluation guides. Results: The patients quality of life worsened the most as a result of anorectal dysfunction. Incontinence of gases and stool, urgency and difficulty in defecation were demonstrated primarily in patients undergoing low rectal resection and irradiation. Patients undergoing radiotherapy, as a result of persistent low anterior resection syndrome, were forced to partially or completely withdraw from professional activity and to limit the pursuit of their interests. Their contacts with family, friends and acquaintances have also deteriorated. The presence of the intestinal stoma significantly affected the deterioration of the reception of the body's own image. However, no relation was found between the existence of the fistula and other aspects of the patients everyday life, including functioning in life and social roles. Conclusions: Due to the acceptable postoperative quality of life of patients with fistula and numerous imperfections of sphincter preserving techniques, operations resulting in terminal ostomy should not be considered as an extremity, and in the case of tumors of the lower rectum with unaffected sphincters, they should be considered as alternative methods for low anterior resection.
    Źródło:
    Polish Journal of Surgery; 2021, 93, 3; 1-9
    0032-373X
    2299-2847
    Pojawia się w:
    Polish Journal of Surgery
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Identification of serum proteome components associated with progression of non-small cell lung cancer
    Autorzy:
    Pietrowska, Monika
    Jelonek, Karol
    Michalak, Malwina
    Roś, Małgorzata
    Rodziewicz, Paweł
    Chmielewska, Klaudia
    Polański, Krzysztof
    Polańska, Joanna
    Gdowicz-Kłosok, Agnieszka
    Giglok, Monika
    Suwiński, Rafał
    Tarnawski, Rafał
    Dziadziuszko, Rafał
    Rzyman, Witold
    Widłak, Piotr
    Powiązania:
    https://bibliotekanauki.pl/articles/1039297.pdf
    Data publikacji:
    2014
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    cancer staging
    early detection
    lung cancer
    proteomics
    serum biomarkers
    Opis:
    The aim of the present study was to perform comparative analysis of serum from patients with different stages of non-small cell lung cancer (NSCLC) using the three complementary proteomic approaches to identify proteome components associated with the progression of cancer. Serum samples were collected before any treatment from 200 patients with NSCLC, including 103 early stage, 64 locally advanced and 33 metastatic cancer samples, and from 200 donors without malignancy. The low-molecular-weight fraction of serum proteome was MALDI-profiled in all samples. Serum proteins were characterized using 2D-PAGE and LC-MS/MS approaches in a representative group of 30 donors. Several significant differences were detected between serum samples collected from patients with early stage cancer and patients with locally advanced cancer, as well as between patients with metastatic cancer and patients with local disease. Of note, serum components discriminating samples from early stage cancer and healthy persons were also detected. In general, about 70 differentiating serum proteins were identified, including inflammatory and acute phase proteins already reported to be associated with the progression of lung cancer (serum amyloid A or haptoglobin). Several differentiating proteins, including apolipoprotein H or apolipoprotein A1, were not previously associated with NSCLC. No significant differences in patterns of serum proteome components were detected between patients with adenocarcinoma and squamous cell carcinoma. In conclusion, we identified the biomarker candidates with potential importance for molecular proteomic staging of NSCLC. Additionally, several serum proteome components revealed their potential applicability in early detection of the lung cancer.
    Źródło:
    Acta Biochimica Polonica; 2014, 61, 2; 325-331
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
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