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    Wyświetlanie 1-7 z 7
    Tytuł:
    Fatigue characteristics of materials used in transport industry applications
    Autorzy:
    Belan, Juraj
    Kuchariková, Lenka
    Mazur, Magdalena
    Tillová, Eva
    Chalupová, Mária
    Powiązania:
    https://bibliotekanauki.pl/articles/88678.pdf
    Data publikacji:
    2019
    Wydawca:
    Stowarzyszenie Menedżerów Jakości i Produkcji
    Tematy:
    fatigue properties
    Inconel alloy
    aluminum alloy
    fatigue fracture
    transportation safety
    właściwości zmęczeniowe
    stop Inconel
    stop aluminium
    pęknięcie zmęczeniowe
    próba zmęczeniowa
    bezpieczeństwo transportu
    Opis:
    Designers have a major interest about fatigue properties of materials used in transport industry. Each component in transport works under alternating stress. From this point of view the fatigue properties are important for single parts lifetime resulting into safety of whole components as cars and airplanes what leads to safety on the roads or air and have influence on human life as well. Therefore this paper deals with fatigue properties of wrought Inconel alloy IN 718 and aluminum cast alloy AlSi9Cu3. Both materials were put on fatigue push – pull test, but Ni – based IN 718 alloy at frequency of loading around 20 000 kHz (High Frequency High Cycles Fatigue) and aluminum alloy AlSi9Cu3 at frequency of loading around 80 Hz (Low Frequency High Cycles Fatigue). These parameters were chosen with respect of usage such materials for production of components used in transport industry applications. Results after fatigue tests are presented as Wohler curve. For prediction of source of fracture the SEM fractography analysis of fatigue fracture surfaces was made.
    Źródło:
    System Safety : Human - Technical Facility - Environment; 2019, 1, 1; 810-818
    2657-5450
    Pojawia się w:
    System Safety : Human - Technical Facility - Environment
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Gelsolin in human colon adenocarcinoma cells with different metastatic potential
    Autorzy:
    Litwin, Monika
    Mazur, Antonina
    Nowak, Dorota
    Mannherz, Hans
    Malicka-Błaszkiewicz, Maria
    Powiązania:
    https://bibliotekanauki.pl/articles/1040503.pdf
    Data publikacji:
    2009
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    gelsolin
    actin
    cancer
    Opis:
    Gelsolin, one of a major actin-binding proteins, is involved in the regulation of actin cytoskeleton organization by its severing and capping activity towards actin filaments. Human colon adenocarcinoma cell line LS180 and its selected variants of different metastatic potential were used to check for a correlation between gelsolin level, its subcellular localization and the invasive capacity of cells. Based on immunoblotting experiments, a decreased level of gelsolin was detected in the most invasive 5W subline when compared to the parental cell line LS180. The intracellular distribution of actin filaments and gelsolin in colon adenocarcinoma cells was examined by confocal microscopy. In the 5W subline, unlike in the other examined cells, gelsolin was colocalized with filamentous actin at the cell periphery. In summary, in human colon adenocarcinoma cells, gelsolin level and its subcellular distribution seem to correlate with their metastatic potential.
    Źródło:
    Acta Biochimica Polonica; 2009, 56, 4; 739-743
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Delusional Misidentification Syndrome: dissociation between recognition and identification processes
    Autorzy:
    Leis, Kamil
    Mazur, Ewelina
    Racinowski, Mariusz
    Jamrożek, Tomasz
    Gołębiewski, Jakub
    Gałązka, Przemysław
    Pąchalska, Maria
    Powiązania:
    https://bibliotekanauki.pl/articles/2106025.pdf
    Data publikacji:
    2019-12-18
    Wydawca:
    Fundacja Edukacji Medycznej, Promocji Zdrowia, Sztuki i Kultury Ars Medica
    Tematy:
    intermetamorphosis syndrome
    Fregoli syndrome
    Capgras syndrome
    delusional misidentification syndromes
    schizophrenia
    Opis:
    Delusional misidentification syndrome (DMS) is an umbrella term for syndromes of intermetamorphosis, Fregoli, and Capgras. DMS) is thought to be related to dissociation between recognition and identification processes. DMS was described for the first time in 1932 as a variant of the Capgras syndrome and is currently on the DSM-V list of diseases as an independent disease entity. Patients affected by DMS believed that people around them, most often family, have changed physically (appearance) and mentally (character). Other symptoms include confabulation, derealization or depersonalization. In patients, aggressive behavior is often observed, aimed at alleged doppelgangers resulting from the sense of being cheated and manipulated. With the intermetamorphosis syndrome, for example, schizophrenia, depression, bipolar disorder or other misidentification syndromes (Fregoli's, Capgras) may coexist. There is also a reverse intermetamorphosis, where the object of the changed appearance or character becomes the patient himself. One of its forms may be lycanthropy. The etiology of the intermetamorphosis has not been fully understood, one of the reasons may be brain damage and changes in the parietal and/or temporal lobes of the right hemisphere. It may then damage long neuronal connections to the frontal areas of the brain, disturbances of working memory (WM) accountable for the keep and online management of data, so that it is available for further processing, and the patient's will be uncritical. The basic method of diagnosis of this delusion is a medical interview with the patient. Other diagnostic methods include computed tomography, magnetic resonance imaging, EEG and ERPs. Experimental methods include searching for the neuromarker of DMS. Currently, there are no treatment guidelines of this delusional disorder, and pharmacotherapy experimental, but the drugs from the group of neuroleptics and lithium seem effective. Some hope for the treatment is created by neurotherapy, but it is also experimental.
    Źródło:
    Acta Neuropsychologica; 2019, 17(4); 456-467
    1730-7503
    2084-4298
    Pojawia się w:
    Acta Neuropsychologica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    First report of a Staphylococcus caprae isolated from middle ear fluid of an infant with recurrent acute otitis media
    Autorzy:
    Mazur, Elżbieta
    Żychowski, Piotr
    Juda, Marek
    Korona-Głowniak, Izabela
    Niedzielska, Grażyna
    Malm, Anna
    Kozioł-Montewka, Maria
    Powiązania:
    https://bibliotekanauki.pl/articles/991004.pdf
    Data publikacji:
    2017
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    staphylococcus caprae
    recurrent acute otitis media
    middle ear fluid
    antimicrobial susceptibility
    biochemical profile
    Opis:
    Staphylococcus caprae was originally isolated from goat milk. This uncommon coagulase-negative staphylococcus, usually associated with animals, has only infrequently been detected in human clinical specimens. Its association with acute otitis media has not been demonstrated so far. The study reports the first isolation of S. caprae from the middle ear fluid of a 12-month-old infant with recurrent, bilateral acute otitis media. Biochemical traits and susceptibility pattern of the isolated strain are also presented.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2017, 24, 3
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Arabidopsis thaliana Nudix hydrolase AtNUDT7 forms complexes with the regulatory RACK1A protein and Ggamma subunits of the signal transducing heterotrimeric G protein
    Autorzy:
    Olejnik, Kamil
    Bucholc, Maria
    Anielska-Mazur, Anna
    Lipko, Agata
    Kujawa, Martyna
    Modzelan, Marta
    Augustyn, Agnieszka
    Kraszewska, Elzbieta
    Powiązania:
    https://bibliotekanauki.pl/articles/1039863.pdf
    Data publikacji:
    2011
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    protein complexes
    Nudix
    AtNUDT7
    Arabidopsis thaliana
    heterotrimeric G protein
    RACK1A
    Opis:
    Arabidopsis thaliana AtNUDT7 Nudix pyrophosphatase hydrolyzes NADH and ADP-ribose in vitro and is an important factor in the cellular response to diverse biotic and abiotic stresses. Several studies have shown that loss-of-function Atnudt7 mutant plants display many profound phenotypes. However the molecular mechanism of AtNUDT7 function remains elusive. To gain a better understanding of this hydrolase cellular role, proteins interacting with AtNUDT7 were identified. Using AtNUDT7 as a bait in an in vitro binding assay of proteins derived from cultured Arabidopsis cell extracts we identified the regulatory protein RACK1A as an AtNUDT7-interactor. RACK1A-AtNUDT7 interaction was confirmed in a yeast two-hybrid assay and in a pull-down assay and in Bimolecular Fluorescence Complementation (BiFC) analysis of the proteins transiently expressed in Arabidopsis protoplasts. However, no influence of RACK1A on AtNUDT7 hydrolase catalytic activity was observed. In vitro interaction between RACK1A and the AGG1 and AGG2 gamma subunits of the signal transducing heterotrimeric G protein was also detected and confirmed in BiFC assays. Moreover, association between AtNUDT7 and both AGG1 and AGG2 subunits was observed in Arabidopsis protoplasts, although binding of these proteins could not be detected in vitro. Based on the observed interactions we conclude that the AtNUDT7 Nudix hydrolase forms complexes in vitro and in vivo with regulatory proteins involved in signal transduction. Moreover, we provide the initial evidence that both signal transducing gamma subunits bind the regulatory RACK1A protein.
    Źródło:
    Acta Biochimica Polonica; 2011, 58, 4; 609-616
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    VDR gene single nucleotide polymorphisms and their association with risk of oral cavity carcinoma
    Autorzy:
    Małodobra-Mazur, Małgorzata
    Paduch, Agnieszka
    Lebioda, Arleta
    Konopacka, Maria
    Rogoliński, Jacek
    Szymczyk, Cezary
    Wierzgoń, Janusz
    Maciejewski, Adam
    Chmielik, Ewa
    Jonkisz, Anna
    Półtorak, Stanisław
    Dobosz, Tadeusz
    Powiązania:
    https://bibliotekanauki.pl/articles/1039670.pdf
    Data publikacji:
    2012
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    VDR gene
    SNP
    oral cavity cancer
    Opis:
    Vitamin D3 (1,25(OH)2D3 (1,25-dihydroxyvitamin D3)) is a hormone playing a crucial role in numerous biological processes in the human body, including induction and control of cell proliferation and differentiation. Numerous data relate the vitamin D3 level with various types of cancer. It has been suggested that SNPs in the vitamin D3 receptor (VDR) gene might influence both the risk of cancer occurrence and cancer progression. The aim of this study was to search for genetic correlations between individual SNPs in the VDR gene and the risk of oral cavity carcinoma. Two SNPs were selected based on the literature and our previous results. Seventy-three patients with squamous cell carcinoma of the head and neck and one hundred control subjects were investigated. Two SNPs in the VDR gene were genotyped in minisequencing reactions followed by capillary electrophoresis. Hardy-Weinberg equilibrium (HWE), the χ2 test and logistic regression were used for statistical analysis. The SNP rs2238135 in the VDR gene displayed statistical differences in frequency between the tested groups (p=0,0007). Furthermore, the G/C genotype of the rs2238135 in the VDR gene was characterized by a 3.16 fold increased risk of oral cavity carcinoma. The obtained results provide evidence for a genetic association between rs2238135 in the VDR gene and the occurrence and risk of oral cavity cancer.
    Źródło:
    Acta Biochimica Polonica; 2012, 59, 4; 627-630
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Radon intercomparison tests : Katowice, 2016
    Autorzy:
    Chałupnik, Stanisław
    Skubacz, Krystian
    Wysocka, Małgorzata
    Mazur, Jadwiga
    Bonczyk, Michał
    Kozak, Krzysztof
    Grządziel, Dominika
    Urban, Paweł
    Tchorz-Trzeciakiewicz, D.
    Kozłowska, Beata
    Walencik-Łata, Agata
    Podstawczyńska, Agnieszka
    Olszewski, Jerzy
    Bartak, Jakub
    Karpińska, Maria
    Wołoszczuk, Katarzyna
    Dohojda, Marek
    Nowak, Jakub
    Długosz-Lisiecka, Magdalena
    Foerster, Elisabeth
    Przylibski, Tadeusz A.
    Powiązania:
    https://bibliotekanauki.pl/articles/146183.pdf
    Data publikacji:
    2020
    Wydawca:
    Instytut Chemii i Techniki Jądrowej
    Tematy:
    active monitors
    passive monitors
    Polish Radon Centre
    proficiency test
    radon
    Opis:
    At the beginning of the year 2016, the representatives of the Polish Radon Centre decided to organize proficiency tests (PTs) for measurements of radon gas and radon decay products in the air, involving radon monitors and laboratory passive techniques. The Silesian Centre for Environmental Radioactivity of the Central Mining Institute (GIG), Katowice, became responsible for the organization of the PT exercises. The main reason to choose that location was the radon chamber in GIG with a volume of 17 m3 , the biggest one in Poland. Accordingly, 13 participants from Poland plus one participant from Germany expressed their interest. The participants were invited to inform the organizers about what types of monitors and methods they would like to check during the tests. On this basis, the GIG team prepared the proposal for the schedule of exercises, such as the required level(s) of radon concentrations, the number and periods of tests, proposed potential alpha energy concentration (PAEC) levels and also the overall period of PT. The PT activity was performed between 6th and 17th June 2016. After assessment of the results, the agreement between radon monitors and other measurement methods was confirmed. In the case of PAEC monitors and methods of measurements, the results of PT exercises were consistent and confirmed the accuracy of the calibration procedures used by the participants. The results of the PAEC PTs will be published elsewhere; in this paper, only the results of radon intercomparison are described.
    Źródło:
    Nukleonika; 2020, 65, 2; 127-132
    0029-5922
    1508-5791
    Pojawia się w:
    Nukleonika
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-7 z 7

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