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Wyświetlanie 1-11 z 11
Tytuł:
Analysis of Thin Films by Time-of-Flight Low Energy Ion Scattering
Autorzy:
Průša, S.
Kolíbal, M.
Bábor, P.
Mach, J.
Šikola, T.
Powiązania:
https://bibliotekanauki.pl/articles/2047292.pdf
Data publikacji:
2007-03
Wydawca:
Polska Akademia Nauk. Instytut Fizyki PAN
Tematy:
68.49.Sf
81.05.Cy
68.55.-a
81.15.Ef
Opis:
In the paper the design and application of a time-of-flight low energy ion scattering instrument built into an UHV complex deposition and analytical apparatus is described. A special attention is aimed at demonstrating the ability of time-of-flight low energy ion scattering to analyse near-to-surface layers of thin films prepared both ex situ and in situ. It is shown that the broadening of peaks in time-of-flight low energy ion scattering spectra can be attributed to multiple scattering and inelastic losses of ions in deeper layers. As a result of that, the peak width of ultrathin films depends on their thickness.
Źródło:
Acta Physica Polonica A; 2007, 111, 3; 335-341
0587-4246
1898-794X
Pojawia się w:
Acta Physica Polonica A
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
The effects of increased inspired oxygen with and without dopamine on lung and diaphragm hydrogen peroxide and apoptosis following hemorrhagic shock
Autorzy:
Mach, W.J.
Thimmesch, A.R.
Slusser, J.G.
Clancy, R.L.
Pierce, J.D.
Powiązania:
https://bibliotekanauki.pl/articles/3448.pdf
Data publikacji:
2010
Wydawca:
Instytut Medycyny Wsi
Tematy:
reactive oxygen species
dopamine
lung
hydrogen peroxide
apoptosis
hemorrhagic shock
DNA damage
hemodynamics
acid-base balance
hyperoxia
Źródło:
Journal of Pre-Clinical and Clinical Research; 2010, 04, 1
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Influence of pre- pro- and synbiotics on the proper functioning of the Gut-Brain Axis and cognition in exposure to stress – review of the latest scientific reports from in vivo studies
Autorzy:
Szala-Rycaj, J.
Szewczyk, A.
Zagaja, M.
Andres-Mach, M.
Powiązania:
https://bibliotekanauki.pl/articles/28761767.pdf
Data publikacji:
2022
Wydawca:
Instytut Medycyny Wsi
Źródło:
Annals of Agricultural and Environmental Medicine; 2022, 29, 3; 326-335
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Attitudes of Poles towards science in the COVID-19 pandemic
Stosunek Polaków do nauki w pandemii COVID-19
Autorzy:
Sadowski, Ireneusz
Kołczyńska, Marta J.
Ciepielewska-Kowalik, Anna
Mach, Bogdan W.
Powiązania:
https://bibliotekanauki.pl/articles/1996051.pdf
Data publikacji:
2021
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
pandemic
COVID-19
science
trust
academic freedom
attitudes
Opis:
The article presents results of a survey of attitudes toward experts’ recommen- dations in fighting COVID-19 pandemic, scientists and science in general, and academic freedom in Poland, and discusses them in the context of the on-going pandemic as well as local developments in Poland. The global crisis triggered by the coronavirus pandemic highlighted the subtle, yet vital social role played by science, which in normal circumstances does not present itself that vividly. This, paradoxically, comes at a time, when the status of science and scientific freedom is disputed in the Polish public debate. The internet survey was conducted by the Institute of Political Studies of the Polish Academy of Sciences in April 2021 on a sample of Poles aged 18–65.
Źródło:
Nauka; 2021, 4; 19-36
1231-8515
Pojawia się w:
Nauka
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
No effect of 7-nitroindazole on the anticonvulsant action of vigabatrin and oxcarbazepine in pentylenetetrazole-induced seizures in mice
Autorzy:
Luszczki, J.J.
Szadkowski, M.
Zadrozniak, A.
Wojda, E.
Dudra-Jastrzebska, M.
Andres-Mach, M.
Powiązania:
https://bibliotekanauki.pl/articles/3243.pdf
Data publikacji:
2008
Wydawca:
Instytut Medycyny Wsi
Tematy:
7-nitroindazole
anticonvulsant action
vigabatrin
oxcarbazepine
pentylenetetrazole-induced seizure
mice
mouse
nitric oxide
neurotransmitter
Źródło:
Journal of Pre-Clinical and Clinical Research; 2008, 02, 2
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
No effect of water extract of Scutellariae radix on the anticonvulsant action of valproate, tiagabine and topiramate in two animal models of epilepsy
Autorzy:
Andres-Mach, M.
Dudra-Jastrzebska, M.
Heratym-Maj, A.
Czerwonka, A.
Raszewski, G.
Luszczki, J.J.
Powiązania:
https://bibliotekanauki.pl/articles/3723.pdf
Data publikacji:
2009
Wydawca:
Instytut Medycyny Wsi
Źródło:
Journal of Pre-Clinical and Clinical Research; 2009, 03, 2
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Characterization of acute adverse-effect profi le of carbamazepine and valproate in the grip-strength test in mice
Autorzy:
Luszczycki, J.J.
Zadrozniak, A.
Wlaz, A.
Andres-Mach, M.
Dudra-Jastrzebska, M.
Zwolinski, J.
Misiuta-Krzesinska, M.
Sielski, M.
Powiązania:
https://bibliotekanauki.pl/articles/3446.pdf
Data publikacji:
2008
Wydawca:
Instytut Medycyny Wsi
Źródło:
Journal of Pre-Clinical and Clinical Research; 2008, 02, 1
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Topinambur - new possibilities for use in a supplementation diet
Autorzy:
Szewczyk, A.
Zagaja, M.
Bryda, J.
Kosikowska, U.
Stepien-Pysniak, D.
Winiarczyk, S.
Andres-Mach, M.
Powiązania:
https://bibliotekanauki.pl/articles/2082014.pdf
Data publikacji:
2018
Wydawca:
Instytut Medycyny Wsi
Tematy:
Topinambur
microbiota
prebiotics
biofuels
Opis:
Jerusalem artichoke (Helianthus tuberosus Linne) is a tuberous perennial plant of the Asteraceae family, which originates from North America, and is also known as wild sunflower or topinambur (TPB). It is characterized by good tolerance to frost, drought and poor soil, strong resistance to pests and plant diseases. For ages it was cultivated due to being both an edible tuber and having healing properties. In folk medicine, TPB leaves are used for the treatment of bone fractures and pain. TPB tubers are rich in sugar and have therefore been used for the production of functional food ingredients, such as inulin. Moreover, TPB is one of the potential crops for bioenergy production, such as bioethanol, biobuthanol and biodiesel, and chemicals (lactic acid, butyric acid). A number of bioactive compounds from the above ground parts of this plant have been isolated which have demonstrating antifungal, antioxidant and anticancer activities. In recent years, a number of animal experiments have been carried out to assess the health properties of TPB. Obtained results show that TPB possess a wide spectrum of medical applications, e.g. reduction in the levels of plasma glucose, total cholesterol and triglyceride. Interestingly, TPB has been shown to be a valuable alternative source of prebiotic compounds. This review article presents recent scientific reports on the chemical and biological properties of TPB and its potential use as a prebiotic diet supplement.
Źródło:
Annals of Agricultural and Environmental Medicine; 2019, 26, 1; 24-28
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Diltiazem enhances the protective activity of oxcarbazepine against maximal electroshock-induced seizures in mice
Autorzy:
Zadrozniak, A.
Trojnar, M.K.
Trojnar, M.P.
Kimber-Trojnar, Z.
Dudra-Jastrzebska, M.
Andres-Mach, M.M.
Luszczki, J.J.
Powiązania:
https://bibliotekanauki.pl/articles/3526.pdf
Data publikacji:
2008
Wydawca:
Instytut Medycyny Wsi
Tematy:
calcium channel antagonist
diltiazem
protective activity
oxcarbazepine
maximal electroshock-induced seizure
mice
mouse
drug interaction
pharmacodynamic interaction
Źródło:
Journal of Pre-Clinical and Clinical Research; 2008, 02, 2
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Increased neurogenesis after ACEA and levetiracetam treatment in mouse pilocarpine model of epilepsy
Autorzy:
Zagaja, Mirosław
Szewczyk, Aleksandra
Haratym-Maj, Agnieszka
Rola, Radosław
Maj, Maciej
Łuszczki, Jarogniew J.
Anders-Mach, Marta
Powiązania:
https://bibliotekanauki.pl/articles/972512.pdf
Data publikacji:
2017
Wydawca:
Instytut Medycyny Wsi
Tematy:
neurogenesis
neurons
astrocytes
pilocarpine
ACEA
Levetiracetam
Opis:
Introduction and objectives. The aim of the study was to asses the impact of long-term therapy with the second generation antiepileptic drug levetiracetam (LEV) with arachidonyl-2’-chloroethylamide (ACEA), a highly selective cannabinoid CB1 receptor agoniston the process of neurogenesis in a mouse pilocarpine model of epilepsy (PILO). Additionally, a relationship was established between the treatment with ACEA in combination with LEV, and hippocampal neurogenesis in mouse PILO brain. Materials and method. All experiments were performed on adolescent male CB57/BL mice injected i.p. with LEV (10 mg/kg), ACEA (10 mg/kg) and PMSF (30 mg/kg) (phenylmethylsulfonyl fluoride — a substance protecting ACEA against degradation by the fatty-acid amidohydrolase), pilocarpine (PILO, a single dose 290 mg/kg) and methylscopolamine (30 min before PILO to stop the peripheral cholinergic effects of the pilocarpine, 1 mg/kg). The process of neurogenesis was evaluated after10 days treatment with LEV and ACEA. Results. Obtained results indicated that the combinations of ACEA+PMSF+LEV and ACEA +PMSF increased the total number of total newborn cells compared to the control. Moreover, ACEA+PMSF administered alone and in combination with LEV had a significant impact on neurogenesis increasing the total number of newborn neurons compared to the control group. Neither LEV nor PMSF had a significant impact on the number of proliferating cells and newborn neurons when compared to the control PILO group. In turn, LEV administered alone decreased significantly the number of astrocytes. However, ACEA+PMSF has demonstrated significant increase of astrocytes compare to control mice. Conclusions. These data provide substantial evidence that the combination of LEV+ACEA significantly increases the level of newborn neurons in the PILO dentate subgranular zone.
Źródło:
Journal of Pre-Clinical and Clinical Research; 2017, 11, 2; 136-141
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Interactions of retigabine with topiramate in the mouse tonic-clonic seizure model and chimney test - an isobolographic analysis
Autorzy:
Zagaja, Mirosław
Miziak, Barbara
Kondrat-Wróbel, Maria W.
Andres-Mach, Marta
Wróblewska-Łuczka, Paula
Adamczuk, Piotr
Chmura, Robert
Czuczwar, Stanisław Jerzy
Łuszczki, Jarogniew J.
Powiązania:
https://bibliotekanauki.pl/articles/972722.pdf
Data publikacji:
2017
Wydawca:
Instytut Medycyny Wsi
Tematy:
maximal electro-shock
drug interaction
isobolographic analysis
Retigabine
Topiramate
Opis:
Introduction and objectives. Nowadays, one of the treatment options for patients with refractory epilepsy is polytherapy with two or more antiepileptic drugs (AEDs). Retigabine (RTG) is a novel third-generation AED with unique molecular mechanisms of action that has recently been approved as an add-on drug for the treatment of tonic-clonic seizures. To characterize types of interactions between RTG and topiramate (TPM – a second-generation AED), the maximal electroshock- induced seizure model (MES) and chimney test in mice were used. Materials and method. In the MES model, the anticonvulsant effects of the drugs in terms of suppression of tonic-clonic seizures in male albino Swiss mice were assessed. In the chimney test, the acute neurotoxic effects of the drugs with respect to impairment of motor coordination were determined. Type I isobolographic analysis for the combination of RTG and TPM was applied to assess the anticonvulsant and neurotoxic effects in both the MES and chimney tests. Total brain concentrations of RTG and TPM were measured to exclude any pharmacokinetic interaction between drugs. Results. The type I isobolographic analysis of interaction revealed that the combination of RTG with TPM produced additive interaction in the MES test and additivity, with a slight tendency towards antagonism in terms of acute neurotoxic effects in the chimney test. Neither RTG nor TPM mutually affected total brain concentrations in the experimental animals. Conclusions. The isobolographically analyzed combination of RTG with TPM is favourable and may be recommended to some patients with refractory epilepsy.
Źródło:
Journal of Pre-Clinical and Clinical Research; 2017, 11, 1; 61-65
1898-2395
Pojawia się w:
Journal of Pre-Clinical and Clinical Research
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-11 z 11

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