Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

English (EN)·Polski (PL)·Yкраїнський (UK)
Przejdź do strony domowej biblioteki Centralna Biblioteka Wojskowa Link otwiera się w nowym oknie Logo biblioteki Prolib Integro - strona głównaCentralna Biblioteka Wojskowa

Wyszukujesz frazę "Luchowska-Kocot, D." wg kryterium: Autor

  Lista filtrów
Wyrównaj
    Wyświetlanie 1-8 z 8
    Tytuł:
    The influence of lithium and/or selenium on plasma amino acids profile in rats
    Autorzy:
    Kiełczykowska, M.
    Musik, I.
    Luchowska-Kocot, D.
    Polz-Dacewicz, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/28761873.pdf
    Data publikacji:
    2022
    Wydawca:
    Instytut Medycyny Wsi
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2022, 29, 1; 136-142
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    PDGF-BB homodimer serum level – a good indicator of the severity of alcoholic liver cirrhosis
    Autorzy:
    Kurys-Denis, E.
    Prystupa, A.
    Luchowska-Kocot, D.
    Krupski, W.
    Bis-Wencel, H.
    Panasiuk, L.
    Powiązania:
    https://bibliotekanauki.pl/articles/2085441.pdf
    Data publikacji:
    2020
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    alcohol
    liver cirrhosis
    Child-Pugh score
    platelet derived growth factor AA
    platelet growth factor AB
    platelet derived
    growth factor BB
    Opis:
    Introduction. Liver cirrhosis is a chronic disease in which progressive fibrosis is noted. This process leads to changed architectonics of the liver parenchyma and the appearance of regenerative nodules, all of which are caused by pathological activation of the hepatic stellate cells. This process is enhanced on a molecular level by many cytokines, with platelet-derived growth factors (PDGFs) playing the key role. Objective. The aim of the study was to assess serum concentrations of PDGFs active biodymers (PDGF-AA, PDGF-BB and PDGF-AB) in patients with alcoholic liver cirrhosis, and to correlate them with the stage of disease. Materials and method. 64 patients with alcoholic cirrhosis and a control group of 16 healthy individuals were analysed. Liver cirrhosis was determined based on clinical image, history of the patients’ alcohol consumption, laboratory findings and abdominal ultrasonography. The serum PDGF-AA, PDGF-BB and PDGF-AB concentrations were determined using ELISA kits. Results. Serum concentration of PDGF-AA and PDGF-BB homodimers increases in patients with alcoholic liver cirrhosis (p=0.034 and p<0.0001, respectively), unlike the serum concentration of PDGF-AB heterodimer (p>0.05). When the stage of the disease increases, the concentrations of PDGF-AA and PGFD-BB in blood also oncrease. Furthermore, the serum level of both PDGF-AA and PDGF-BB correlates significantly with the severity of alcoholic liver cirrhosis (measured by Pugh-Child’s scale), the correlation being stronger in the case of PDGF-BB levels than PDGF-AA (R=0.28; p=0.027 and R=0.26; p=0.038, respectively). Conclusions. The plasma levels of PDGF-AA and -BB may be indicators of alcohol-induced liver fibrosis process, and might be considered as future possible treatment targets, with PDGF-BB levels being an even better indicator than PDGF-AA levels.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2020, 27, 1; 80-85
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Oxidative stress-induced growth inhibitor 1 in alcohol-induced liver cirrhosis
    Autorzy:
    Sak, J.J.
    Prystupa, A.
    Bis-Wencel, H.
    Kiciński, P.
    Luchowska-Kocot, D.
    Krukowski, H.
    Nowicki, G.J.
    Panasiuk, L.
    Powiązania:
    https://bibliotekanauki.pl/articles/28761891.pdf
    Data publikacji:
    2021
    Wydawca:
    Instytut Medycyny Wsi
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2021, 28, 4; 676-680
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Iron in medicine and treatment
    Żelazo w medycynie i lecznictwie
    Autorzy:
    Luchowska-Kocot, D.
    Powiązania:
    https://bibliotekanauki.pl/articles/13550.pdf
    Data publikacji:
    2014
    Wydawca:
    Uniwersytet Warmińsko-Mazurski w Olsztynie / Polskie Towarzystwo Magnezologiczne im. Prof. Juliana Aleksandrowicza
    Tematy:
    iron
    medicine
    treatment
    iron deficiency
    anaemia
    restless legs syndrome
    Willis-Ekbom disease zob.restless legs syndrome
    Wittmaack-Ekbom syndrome zob.restless legs syndrome
    pregnancy
    Opis:
    Being a component of many proteins and enzymes, iron is an essential microelement for humans. However, this element can also be toxic when present in excess because of its ability to generate reactive oxygen species. This dual nature imposes a strict regulation mechanism of the iron concentration in the body. In humans, systemic iron homeostasis is mainly regulated on the level of intestinal absorption. A patient diagnosed with excess iron in the body should be treated safely and effectively. And the therapy should be consistent with the treatment of concurrent diseases. On the other hand, iron deficiency is one of the most common disorders affecting humans. Iron-deficiency anaemia continues to represent a major public health problem worldwide, being prevalent among pregnant women, where it represents an important risk factor for maternal and infant health. A problem detecetd relatively recently and therefore not fully clarified yet is the iron therapy in patients with restless legs syndrome (RLS). RLS is a common neurological condition defined clinically as the urge to move the legs. Reduced brain iron is strongly associated with restless legs syndrome. RLS can also be a consequence of iron deficiency in the body. This review will focus on iron as an element whose abnormal metabolism or deficiency in the body can lead to diseases e.g. anaemia, restless legs syndrome and iron overload. Here we will describe methods of therapy, paying particular attention to the types and dosages of medications.
    Żelazo jest podstawowym mikroelementem organizmu ludzkiego, stanowi bowiem istotny element wielu białek i enzymów. Jednak pierwiastek ten może wykazywać działanie toksyczne, gdy występuje w nadmiarze, ze względu na jego zdolność do generowania reaktywnych form tlenu. Ten podwójny charakter żelaza narzuca ścisłą regulację stężenia żelaza w organizmie. U ludzi homeostaza ustrojowa żelaza jest głównie regulowana na poziomie wchłaniania jelitowego. Pacjent, u którego zdiagnozowano nadmiar żelaza w organizmie, powinien być poddany bezpiecznemu i skutecznemu leczeniu, które jest zgodne z terapią współistniejących schorzeń. Niedobór żelaza jest jednym z najczęstszych zaburzeń dotykających ludzi. Niedokrwistość spowodowana niedoborem żelaza nadal stanowi istotny problem zdrowia publicznego na całym świecie. Szczególnie dotyczy kobiet w ciąży, stanowiąc istotny czynnik ryzyka dla zdrowia matki i dziecka. Stosunkowo nowym i nie do końca wyjaśnionym zagadnieniem jest terapia żelazem chorych na zespół niespokojnych nóg (RLS). Jest to stan neurologiczny klinicznie określany jako przymus poruszania nogami. Z zespołem niespokojnych nóg związana jest ściśle redukcja żelaza w mózgu. RLS może być również konsekwencją niedoboru żelaza w organizmie. W pracy omówiono nieprawidłowy metabolizm żelaza lub jego brak w organizmie, co może prowadzić do ww. jednostek chorobowych. Opisano również metody terapii, zwracając szczególną uwagę na rodzaj i wielkość dawki proponowanych leków.
    Źródło:
    Journal of Elementology; 2014, 19, 3
    1644-2296
    Pojawia się w:
    Journal of Elementology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Factors influencing serum chemerin and kallistatin concentrations in patients with alcohol-induced liver cirrhosis
    Autorzy:
    Prystupa, A.
    Kiciński, P.
    Luchowska-Kocot, D.
    Sak, J.
    Prystupa, T.K.
    Tan, Y.-H.
    Panasiuk, L.
    Załuska, W.
    Powiązania:
    https://bibliotekanauki.pl/articles/2082078.pdf
    Data publikacji:
    2018
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    alcohol-induced liver cirrhosis
    chemerin
    kallistatin
    Opis:
    Introduction. In Poland, an increasing number of patients are hospitalized due to liver diseases. One of the common liver diseases is cirrhosis, which can be caused by alcohol, viral hepatitis, autoimmune processes and metabolic diseases. Materials and method. The study included 99 patients with alcoholic cirrhosis from the Lublin region of Eastern Poland. The control group consisted of 20 healthy individuals without liver disease who did not abuse alcohol. The concentrations of serum kallistatin and chemerin were determined using ELISA kits. Objective. The aim of the study is to evaluate serum levels of kallistatin and chemerin in patients with different stages of alcoholic liver cirrhosis. Results. The highest chemerin level was found in the control group – 182.6±80.4 ng/ml. In other stages of liver cirrhosis, the following levels were observed: 175.7±62.7 ng/ml in Child-Pugh stage A (Ch-P A), 150.2±59.7 ng/ml in Ch-P B and 110.3±73.6 ng/ml in Ch-P C. Significant differences in chemerin levels between controls and Ch-P C patients (p=0.01), as well as between the Ch-P A patients and Ch-P C patients (p=0.02), were demonstrated. The highest kallistatin level was demonstrated in the control group – 8.2±3.5 μg/ml. In other stages of liver cirrhosis, the following concentrations were found: 7.2±27 μg/ml in Ch-P A, 4.4±2.2 μg/ml in Ch-P B and 3.5±1.9 μg/ml in Ch-P C (Tab. 3). Statistically significant differences were observed between controls and Ch-P B patients (p<0.001), controls and Ch-P C patients (p<0.001), Ch-P A and Ch-P B patients (p=0.01), as well as Ch-P A and Ch-P C patients (<0.001). Conclusions. The levels of chemerin and kallistatin decrease with progression of liver damage during alcoholic liver cirrhosis. The impairment of its synthetic function leads to reductions in levels of the adipokines studied.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2019, 26, 1; 143-147
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Correlations among plasma silicon, magnesium and calcium in patients with knee osteoarthritis - analysis in consideration of gender
    Autorzy:
    Musik, I.
    Kurzepa, J.
    Luchowska-Kocot, D.
    Kocot, J.
    Paździor, M.
    Polz-Dacewicz, M.
    Kiełczykowska, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/2082056.pdf
    Data publikacji:
    2018
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    osteoarthritis of knee
    silicon
    calcium
    magnesium
    males
    females
    Opis:
    Introduction and objective. Osteoarthrits (OA) is a complex, chronic disorder of cartilage and bone, related to homeostasis of bioelements. The current study aimed at evaluation of correlations between plasma silicon, magnesium and ionized calcium in OA patients in consideration to gender. Materials and method. The study comprised 59 patients aged 69.5±9.0 years (18 males aged 66.8±9.2; 41 females aged 70.7±8.8), admitted to the Trauma and Orthopaedic Ward of the Independent Public Health Care Centre in Łęczna, Poland, due to OA and qualified to surgery. Control group consisted of 19 subjects without OA (54.5±8.6 years; 10 males aged 41.3±9.3; 9 females aged 69.1±14.9). Plasma concentrations of silicon and magnesium (spectrophotometric methods) and ionized calcium (potentiometric method) were determined. Results. Silicon in OA patients was significantly increased vs. control. In OA males and OA females, silicon was enhanced vs. the respective controls, but it was statistically significant only in males. Magnesium in OA patients was not significantly different from control group. In females, a significant decrease vs. the respective control was observed. No significant differences were observed in the case of ionized calcium. Positive correlations between silicon and magnesium in healthy control, both in the whole group and in male and female subgroups, were noted, while no such effect was observed in OA subjects. Conclusions. The results might suggest some connection between higher OA incidence in women and the depleted magnesium in the organism. Silicon increase in OA patients, especially in men, may indicate its intense metabolism during the articular inflammatory process, likely dependent on sex hormones. It remains open whether the plasma Si increase is the effect or cause of OA.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2019, 26, 1; 97-102
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Analysis of novel serum markers of fibrosis and angiogenesis in patients with alcoholic liver cirrhosis
    Autorzy:
    Prystupa, A.
    Kiciński, P.
    Luchowska-Kocot, D.
    Nowicki, G.
    Dzida, G.
    Myśliński, W.
    Zakrzewski, M.
    Mosiewicz, J.
    Panasiuk, L.
    Powiązania:
    https://bibliotekanauki.pl/articles/28762972.pdf
    Data publikacji:
    2020
    Wydawca:
    Instytut Medycyny Wsi
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2020, 27, 4; 568-573
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Afamin and adropin in patients with alcohol-induced liver cirrhosis
    Autorzy:
    Prystupa, A.
    Kiciński, P.
    Luchowska-Kocot, D.
    Sak, J.
    Prystupa, T.
    Chen, K.-H.
    Chen, Y.-H.
    Panasiuk, L.
    Załuska, W.
    Powiązania:
    https://bibliotekanauki.pl/articles/2081906.pdf
    Data publikacji:
    2018
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    alcoholic liver cirrhosis
    Adropin
    Child-Pugh score
    afamin
    Opis:
    The aim of the study was to determine serum concentrations of afamin and adropin in patients with alcoholic liver cirrhosis and to define their correlation with the stage of disease. The study included 99 patients with alcoholic cirrhosis from the region of Lublin, (Eastern Poland). Liver cirrhosis was diagnosed based on clinical features, history of heavy alcohol consumption, laboratory tests and abdominal ultrasonography. The control group consisted of 20 healthy individuals without liver disease who did not abuse alcohol. The serum afamin and adropin concentrations were determined using ELISA kits. The concentration of afamin was found to be significantly lower in patients with compensated alcoholic liver cirrhosis, i.e. P-Ch B (85.1±40.6 μg/ml) and P-Ch C (56.4±32.3 μg/ml) individuals, compared to the control group (135.9±43.6 μg/ml); p-value was <0.01 and <0.001, respectively. As far as adropin is concerned, a reverse relationship was demonstrated: the highest concentration was found in patients with P-Ch C (11.7±5.7 ng/ml) cirrhosis. Furthermore, the above concentration was significantly higher compared to patients with P-Ch A cirrhosis (7.2±2.8 ng/ml; p<0.05) and controls (7.5±2.6 ng/ml; p<0.05). The concentration of afamin decreases with the severity of alcoholic liver cirrhosis, which most likely results from impaired hepatic synthesis. Otherwise, the higher the stage of disease according to the Child-Pugh score, the higher the concentration of adropin.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2018, 25, 3; 527-531
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-8 z 8

      Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies