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    Wyświetlanie 1-3 z 3
    Tytuł:
    Preventive use of Lactobacillus plantarum LS/07 and inulin to relieve symptoms of acute colitis
    Autorzy:
    Hijová, Emília
    Šoltésová, Alena
    Salaj, Rastislav
    Kuzma, Jozef
    Strojný, Ladislav
    Bomba, Alojz
    Gregová, Kristína
    Powiązania:
    https://bibliotekanauki.pl/articles/1039004.pdf
    Data publikacji:
    2015
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    colitis
    Sprague-Dawley rats
    inulin
    Lactobacillus plantarum LS/07
    Opis:
    The aim of presented study was to investigate the influence of Lactobacillus plantarum LS/07 and inulin on the activity of β-glucuronidase enzyme, and counts of coliform and lactobacilli in fresh caecal digesta, cytokine levels (IL-6, IL-8), and trancription nuclear factor kappa beta (NFκB) activities in colon tissue and blood samples of rats with dextran sulphate sodium (DSS) induced acute colitis. The rats were randomly divided into four groups - CG, AC, AC+PRE and AC+PRO. Colitis was induced using of 5% DSS in drinking water for 7d. DSS application increased activity of β-glucuronidase (P < 0.001), increased counts of coliforms, and decreased lactobacilli counts (P < 0.05) in comparison to control group. Serum and tissue levels of IL-6 and IL-8 as well as tissue NFκB activities showed increased expression in acute colitis group. Inulin diet modified counts of microorganims and decreased β-glucuronidase activity, suppressed NFκB activities (P < 0.001) and down regulate synthesis of IL-6 (P < 0.01) in serum and colon tissue and tissue IL-8 (P < 0.05). Lactobacillus plantarum LS/07 decreased β-glucuronidase activity (P < 0.05), levels of IL-6 and IL-8 (P < 0.001). These results were consistent with the addition of histological findings. Our results indicate that dietary intake of Lactobacillus plantarum LS/07 and inulin suppressed expression observed markers, which play an important role in the inflammatory process, which predisposes their use in prevention or treatment of acute colitis.
    Źródło:
    Acta Biochimica Polonica; 2015, 62, 3; 553-557
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Ability of Lactobacillus plantarum LS/07 to modify intestinal enzymes activity in chronic diseases prevention
    Autorzy:
    Hijová, Emília
    Kuzma, Jozef
    Strojný, Ladislav
    Bomba, Alojz
    Bertková, Izabela
    Chmelárová, Anna
    Hertelyová, Zdena
    Benetinová, Veronika
    Štofilová, Jana
    Ambro, Ľuboš
    Powiązania:
    https://bibliotekanauki.pl/articles/1038694.pdf
    Data publikacji:
    2017
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    Sprague-Dawley rats
    bacterial enzyme
    cancer
    atherosclerosis
    dysbiosis
    Opis:
    The ability of probiotic strain Lactobacillus plantarum LS/07 to modify the activity of intestinal bacterial enzymes - β-glucuronidase (β-GLUCUR), β-galactosidase (β-GAL), and β-glucosidase (β-GLU) in prevention of chronic diseases - cancer, atherosclerosis and dysbiosis was investigated. The male Sprague-Dawley rats were randomly divided into 12 experimental groups: controls groups - C (control), AT (atherosclerotic), CC (carcinogenic), dysbiotic groups - each group in combination with antibiotics (ATB), probiotics groups - in combinatioan with probiotic (PRO) alone, and each group with combination of antibiotic and probiotic (ATB+PRO). In the control group the β-glucuronidase activity did not change throughout the experiment. High fat diet in atherosclerotic group significantly increased the activity of β-glucuronidase (P<0.001) and β-glucosidase (P<0.01). Azoxymethane application in carcinogenic group significantly increased β-glucuronidase (P<0.01), but reduced β-glucosidase (P<0.01) activity. Daily application of probiotics alone and in combination with antibiotic increased β-galactosidase, of β-glucosidase, and decreased β-glucuronidase activity. In control antibiotic group we observed significant increase in β-glucuronidase (P<0.05) and decreased β-glucosidase (P<0.01) activity which can be caused by the change of microflora in favor of coliform bacteria. These findings indicate the positive effects of probiotic Lactobacillus plantarum LS/07 and suggest its use in disease prevention in human medicine and some animal species.
    Źródło:
    Acta Biochimica Polonica; 2017, 64, 1; 113-116
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Identification of leading factors supporting decisions in preventive quality management
    Autorzy:
    Misztal, Agnieszka
    Drzewiecka-Dahlke, Milena
    Marczewska-Kuźma, Roma
    Gruszka, Józef
    Powiązania:
    https://bibliotekanauki.pl/articles/27313507.pdf
    Data publikacji:
    2022
    Wydawca:
    Politechnika Śląska. Wydawnictwo Politechniki Śląskiej
    Tematy:
    decision making
    prevention of non-conformities
    quality management
    podejmowanie decyzji
    zapobieganie niezgodnościom
    zarządzanie jakością
    Opis:
    Purpose: The main aim of the article is to present the results of research of entrepreneurs who maintain a certified quality management system in terms of leading factors supporting decisions of a preventive approach to management. Design/methodology/approach: Interview method conducted in manufacturing companies with an implemented and certified quality management system using CATI technique Findings: Research has shown that in large industrial enterprises the key stimulants of preventive actions are, above all, efficient information flow, technical and organizational order, as well as consistent pursuit of the goal. Smaller enterprises put the main emphasis on maintaining good relations with the environment, safety and ergonomics of work, as well as skillful selection of suppliers. Research limitations/implications: The authors of the paper see the need to continue research in the field of in-depth analysis of selected factors in relation to the effectiveness of the actions taken and the possibility of supporting information. Practical implications: Entrepreneurs with knowledge of key stimulants will make decisions more consciously and focused on a targeted analysis of data in order to search for relevant premises to prevent non-compliance. Originality/value: This paper concerns key factors influencing a preventive approach that can support decision-making. For the purposes of multicriteria decision-making processes, it is valuable to know the key stimuli characteristic of effective preventive actions. An additional value of the article is the showing of the factors with a differentiation by company size. This enables a more relevant focus of the research results.
    Źródło:
    Zeszyty Naukowe. Organizacja i Zarządzanie / Politechnika Śląska; 2022, 162; 473--500
    1641-3466
    Pojawia się w:
    Zeszyty Naukowe. Organizacja i Zarządzanie / Politechnika Śląska
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-3 z 3

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