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Wyszukujesz frazę "Khan, Mahmood" wg kryterium: Autor


Wyświetlanie 1-5 z 5
Tytuł:
Biotechnology of temperate fruit trees and grapevines
Autorzy:
Laimer, Margit
Mendonça, Duarte
Maghuly, Fatemeh
Marzban, Gorji
Leopold, Stephan
Khan, Mahmood
Balla, Ildiko
Katinger, Hermann
Powiązania:
https://bibliotekanauki.pl/articles/1041374.pdf
Data publikacji:
2005
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
plant biotechnology
patogen detection
molecular markers
Opis:
Challenges concerning fruit trees and grapevines as long lived woody perennial crops require adapted biotechnological approaches, if solutions are to be found within a reasonable time frame. These challenges are represented by the need for correct identification of genetic resources, with the foreseen use either in conservation or in breeding programmes. Molecular markers provide most accurate information and will be the major solution for questions about plant breeders rights. Providing healthy planting material and rapid detection of newly introduced pathogens by reliable methods involving serological and molecular biological tools will be a future challenge of increases importance, given the fact that plant material travels freely in the entire European Union. But also new breeding goals and transgenic solutions are part of the biotechnological benefits, e.g. resistance against biotic and abiotic stress factors, modified growth habits, modified nutritional properties and altered processing and storage qualities. The successful characterization of transgenic grapevines and stone fruit trees carrying genes of viral origin in different vectors constructed under ecological consideration, will be presented. Beyond technical feasibility, efficiency of resistance, environmental safety and Intellectual Property Rights, also public acceptance needs consideration and has been addressed in a specific project. The molecular determination of internal quality parameters of food can also be addressed by the use of biotechnological tools. Patient independent detection tools for apple allergens have been developed and should allow to compare fruits from different production systems, sites, and genotypes for their content of health threatening compounds.
Źródło:
Acta Biochimica Polonica; 2005, 52, 3; 673-678
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
USE OF GLUTARIC ACID TO IMPROVE THE SOLUBILITY AND DISSOLUTION PROFILE OF GLIPIZIDE THROUGH PHARMACEUTICAL COCRYSTALLIZATION
Autorzy:
Batool, Fakhra
Ahmad, Mahmood
Minhas, Muhammad U.
Khalid, Qandeel
Idrees, Hafiz A.
Khan, Fahad M.
Powiązania:
https://bibliotekanauki.pl/articles/895470.pdf
Data publikacji:
2019-02-28
Wydawca:
Polskie Towarzystwo Farmaceutyczne
Tematy:
FTIR
SEM
PXRD
thermal analysis
glipizide
glutaric acid
Opis:
The purpose of current study was to improve the solubility and dissolution profile of BCS class-II drug Glipizide using glutaric acid as a coformer via various cocrystalization techniques i.e., dry grinding, liquid assisted grinding, slurry and solvent evaporation. Fourier Transform Infrared Spectroscopy (FTIR) was performed to determine the interaction between components of glipizide-glutaric acid (GPZ-GLU) cocrystals. Powder X-ray Diffraction (PXRD) studies confirmed the crystalline nature of formulated cocrystals. Scanning Electron Microscopy (SEM) revealed cylindrical to rectangular shape of cocrystals. Flow properties of GPZ-GLU cocrystals were evaluated by micromeritics analysis. Size and surface morphology was determined by zeta sizer analysis and optical microscopy. Differential scanning calorimetry (DSC) and Thermogravimetric (TGA) analysis were performed to determine the melting points as well as thermal stability of pure components and formulated GPZ-GLU cocrystals. In-vitro drug release studies were carried out using dissolution apparatus-II. GPZ-GLU cocrystals showed higher drug release at pH 6.8 as compared to pH 1.2. However, percent drug release of optimum formulations at pH 6.8 was determined as; 24%-92.2% (F3) and 12.0%-93.5% (F7). Solubility studies revealed improved solubility as compared to pure drug in water i.e., 53 folds and 54.27 folds from F3 and F7 cocrystals, respectively. Finally it was concluded that glutaric acid has improved the solubility and dissolution profile of glipizide. However, many cocrystal formers have been reported in literature that can be used to enhance the physicochemical properties as well as bioavailability of poorly soluble drugs via cocrystalization technique.
Źródło:
Acta Poloniae Pharmaceutica - Drug Research; 2019, 76, 1; 103-114
0001-6837
2353-5288
Pojawia się w:
Acta Poloniae Pharmaceutica - Drug Research
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Holistic human resource development model in health sector : a phenomenological approach
Holistyczny model rozwoju zasobów ludzkich w sektorze zdrowia : podejście fenomenologiczne
Autorzy:
Arshad, Mohd Anuar
Shabbir, Muhammad Salman
Mahmood, Arshad
Sulaiman, Mohammed Ali Bait Ali
Khan, Shahid
Powiązania:
https://bibliotekanauki.pl/articles/405991.pdf
Data publikacji:
2019
Wydawca:
Politechnika Częstochowska
Tematy:
spiritual quotient
human resource development
HRD
phenomenological approach
iloraz duchowy
rozwój zasobów ludzkich
podejście fenomenologiczne
Opis:
This study proposed holistic human resource development model in health sector. This study focused on human resources (HR) managers and the top management of the health sector in Pakistan. Using a qualitative methodology, the researcher focused on the selected phenomenological method. In this study, primary data collection was conducted through personal interviews with human resource managers and the top management of three health organizations in Pakistan. With regard to the sampling technique, the study would be based on a specific sampling. This article presents the results of the three research objectives. The first research objective examines the development and implementation process of the human resource development model in organizations. Second, intelligence quotient and emotion quotient programs are defined by organizations within the current human resource development models. Third, this study examines the organization's understanding of spiritual quotient and evaluates awareness of the importance of spiritual quotient for the development of human resource development model. It suggests that spiritual quotient is an important part of organizational development.
W badaniu zaproponowano holistyczny model rozwoju zasobów ludzkich w sektorze opieki zdrowotnej. To badanie koncentrowało się na menedżerach ds. Zasobów ludzkich (HR) i najwyższym kierownictwie sektora opieki zdrowotnej w Pakistanie. Korzystając z metodologii jakościowej, badacz skoncentrował się na wybranej metodzie fenomenologicznej. W tym badaniu gromadzono dane pierwotne w drodze wywiadów osobistych z menedżerami ds. Zasobów ludzkich i najwyższym kierownictwem trzech organizacji zdrowotnych w Pakistanie. W odniesieniu do techniki pobierania próbek badanie opierałoby się na konkretnym pobieraniu próbek. W tym artykule przedstawiono wyniki trzech celów badawczych. Pierwszy cel badawczy dotyczy procesu opracowywania i wdrażania modelu rozwoju zasobów ludzkich w organizacjach. Po drugie, iloraz inteligencji i iloraz emocji są definiowane przez organizacje w ramach obecnych modeli rozwoju zasobów ludzkich. Po trzecie, badanie to bada zrozumienie ilorazu duchowego przez organizację i ocenia świadomość znaczenia ilorazu duchowego dla rozwoju modelu rozwoju zasobów ludzkich. Sugeruje, że iloraz duchowy jest ważną częścią rozwoju organizacji.
Źródło:
Polish Journal of Management Studies; 2019, 20, 1; 44-53
2081-7452
Pojawia się w:
Polish Journal of Management Studies
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Comparative evaluation of different techniques for herniorrhaphy in calves
Autorzy:
Fatima, A.
Arif Khan, M.
Aslam, S.
Ashraf, K.
Khalid Mahmood, A.
Asif, M.
Shah, S.
Hussain, N.
Powiązania:
https://bibliotekanauki.pl/articles/16539145.pdf
Data publikacji:
2022
Wydawca:
Polska Akademia Nauk. Czasopisma i Monografie PAN
Tematy:
calves
mesh application
suture material
umbilical hernia
Opis:
Umbilical hernia is one of the most common problems in young calves. This problem occurs in dairy sector as well as in the local farmers. Present study was conducted to compare outcomes of four different techniques of herniorrhaphy. Twenty four young calves (n=24) were divided in 4 groups (A, B, C, and D) which underwent four different surgical techniques. Group A underwent vicryl plus suture material and pants-over-west technique, Group B underwent mesh application with Dexon suture material by using simple interrupted suture pattern, Group C underwent closed method with Nylon No. 3 suture material by using vertical mattress suture pattern and Group D underwent clamp application method with Silk No. 2 suture material by using simple interrupted suture pattern. The result showed that mesh application method was comparatively better with respect to feed intake, body weight gain and healing time. There was no reoccurrence with non-significant hematological changes (p≤0.05). It is concluded that mesh application method is safer than other three techniques and there are no systemic effects of this surgical intervention on calves’ health.
Źródło:
Polish Journal of Veterinary Sciences; 2022, 25, 2; 207-212
1505-1773
Pojawia się w:
Polish Journal of Veterinary Sciences
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Proximate analysis of lignocellulosic biomass and its utilization for production, purification and characterization of ligninolytic enzymes by Aspergillus flavus
Autorzy:
Khan, Jehangir
Asad, Muahammad Javaid
Mahmood, Raja Tahir
Wattoo, Feeroza Hamid
Zainab, Tayyaba
Nazir, Sidrah
Shah, Muhammad Basir
Ahmed, Dawood
Powiązania:
https://bibliotekanauki.pl/articles/205277.pdf
Data publikacji:
2020
Wydawca:
Polska Akademia Nauk. Czytelnia Czasopism PAN
Tematy:
Aspergillus flavus
acid detergent lignin
ammonium sulfate
ligninolytic enzymes
Platanus orientalis
Opis:
Ligninolytic enzymes are employed for the production of second-generation biofuel to minimize fuel crisis. Additionally, they play a crucial role in global carbon cycle and a variety of applications in food, agriculture, paper and textile industries. On a large scale production of ligninolytic enzymes, microorganisms can be cultured on lignocellulosic wastes. In the present study, proximate analysis including acid detergent lignin (ADL), acid detergent cellulose (ADC), acid detergent fiber (ADF) and acid insoluble ash (AIA) were performed for Platanus orientalis (chinar), Bauhinia variegata (orchid tree), Pinus roxburghii (chirpine), wheat straw and wheat husk. Platanus orientalis was selected as substrate because of higher lignin contents for the production of ligninolytic enzymes by Aspergillus flavus. Solid State Fermentation was used and Response Surface Methodology was employed for optimizing various parameters and enzymes production. Maximum production was achieved at temperature 32°C, fermentation period 120 hours, pH 4.5, inoculums size 3.5 mL, substrate mesh size 80 mm, substrate size 7 g. Maximum purification of laccase, manganese peroxidase (MnP) and lignin peroxidase (LiP) was achieved with 50%, 60% and 40% ammonium sulfate respectively and it was enhanced by gel filtration chromatography. Characterization of enzymes shows that Laccase has 35°C optimum temperature, 4.5 pH, 0.289 mM Km and 227.27 μM/ml Vmax. Manganese peroxidase has 30°C optimum temperature, 5.5 pH, 0.538 mM Km and 203.08 μM/ml Vmax. Lignin peroxidase has 30°C optimum temperature, 3 pH, 2 mM Km and 2000 uM/ml Vmax. Protein concentrations found in crude extracts and partially purified enzymes are respectively: laccase 1.78 and 0.71 mg/ml, MnP 1.59 and 0.68 mg/ml. LiP, 1.70 and 0.69 mg/ml.
Źródło:
Archives of Environmental Protection; 2020, 46, 1; 3-13
2083-4772
2083-4810
Pojawia się w:
Archives of Environmental Protection
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-5 z 5

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