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Wyszukujesz frazę "Karon, Jacek" wg kryterium: Autor


Wyświetlanie 1-2 z 2
Tytuł:
Foreign Body in the Gastrointestinal Tract Leading to Small Bowel Obstruction - Case Report and Literature Review
Autorzy:
Wnęk, Bartosz
łożyńska-Nelke, Aleksandra
Karoń, Jacek
Powiązania:
https://bibliotekanauki.pl/articles/1395997.pdf
Data publikacji:
2015-03-01
Wydawca:
Index Copernicus International
Tematy:
foreign body
gastrointestinal obstruction
weight loss
Opis:
The presence of a foreign body in the gastrointestinal tract constitutes a common pathology, considering surgical clinical practice. The management of the ingestion of a foreign body depends on many factors. The study presented a case of a 33-year-old female patient subjected to surgical treatment, due to deliberate swallowing of a balloon. The above-mentioned was the amateur equivalent of intragastric balloon insertion, inducing weight loss. This is a rare cause of a foreign body ingestion, seldomly found in literature data. The patient reported to the Emergency Department on the second day after ingestion with symptoms of mechanical subobstruction, and after initial diagnostics, was qualified for surgery. The postoperative period proved uneventful. The study illustrated the often unfavourable access to false data on the internet, which may stimulate towards the above-mentioned behaviour.
Źródło:
Polish Journal of Surgery; 2014, 86, 12; 594-597
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Transcriptional changes between uninflamed ulcerative colitis and familial adenomatous polyposis pouch mucosa can be attributed to an altered immune response
Autorzy:
Paziewska, Agnieszka
Horbacka, Karolina
Goryca, Krzysztof
Mikula, Michal
Jarosz, Dorota
Dabrowska, Michalina
Krokowicz, Piotr
Karon, Jacek
Ostrowski, Jerzy
Powiązania:
https://bibliotekanauki.pl/articles/1039136.pdf
Data publikacji:
2015
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
ulcerative colitis
familial adenomatous polyposis
pouch
gene expression
immune response
Opis:
A total proctocolectomy with ileal pouch-anal anastomosis (IPAA) is considered the surgery of choice for definitive management of familial adenomatous polyposis (FAP) and some patients with ulcerative colitis (UC). However, this surgical treatment is often associated with pouchitis, a long-term complication that occurs mostly in UC patients. The purpose of this study was to better define the molecular background of pouchitis. A microarray-based survey was performed using pouch mucosal samples collected from 28 and 8 patients undergoing surgery for UC and FAP, respectively. There were 4,770 genes that significantly differentiated uninflamed from inflamed mucosal samples, and their functional features were represented mostly by metabolic and cell proliferation pathways. In contrast, functional analyses of aberrantly expressed genes between UC and FAP samples, irrespective of mucosal inflammation status, revealed multiple pathways and terms that were linked to changes in immune response. Interestingly, the comparison of uninflamed UC and FAP samples identified a set of 29 altered probe sets, including an inflammation-related transcript encoding a Charcot-Leyden crystal (CLC) protein. The most distinct changes in gene expression profiles differentiating uninflamed UC and FAP pouch mucosal samples were attributed to the Gene Ontology category innate immune response. Our study confirmed that alterations in immune responses can be found between patients who underwent surgery for UC and FAP, independent of the pouch inflammation status. This observation may be important when managing IPAA patients.
Źródło:
Acta Biochimica Polonica; 2015, 62, 1; 69-75
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-2 z 2

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