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Wyszukujesz frazę "Borowicz, K.K." wg kryterium: Autor

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    Wyświetlanie 1-15 z 15
    Tytuł:
    Isobolographic interaction between AO-294, an enantiomer of losigamone, and valproate in the mouse model of maximal electroshock
    Autorzy:
    Borowicz, K.K.
    Jaszczyk, B.
    Powiązania:
    https://bibliotekanauki.pl/articles/3738.pdf
    Data publikacji:
    2007
    Wydawca:
    Instytut Medycyny Wsi
    Źródło:
    Journal of Pre-Clinical and Clinical Research; 2007, 01, 1
    1898-2395
    Pojawia się w:
    Journal of Pre-Clinical and Clinical Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Effect of IEM 1460 - a selective antagonist of GluR2-lacking AMPA receptors - on the action of conventional antiepileptic drugs against maximal electroshock in mice
    Autorzy:
    Borowicz, K.K.
    Banach, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/3599.pdf
    Data publikacji:
    2007
    Wydawca:
    Instytut Medycyny Wsi
    Źródło:
    Journal of Pre-Clinical and Clinical Research; 2007, 01, 1
    1898-2395
    Pojawia się w:
    Journal of Pre-Clinical and Clinical Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Isobolographic interaction between AO-294, an enantiomer of losigamone, and phenobarbital in the mouse model of maximal electroshock
    Autorzy:
    Borowicz, K.K.
    Jaszczyk, B.
    Powiązania:
    https://bibliotekanauki.pl/articles/3604.pdf
    Data publikacji:
    2007
    Wydawca:
    Instytut Medycyny Wsi
    Źródło:
    Journal of Pre-Clinical and Clinical Research; 2007, 01, 1
    1898-2395
    Pojawia się w:
    Journal of Pre-Clinical and Clinical Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Anticonvulsant activity of convntional antiepileptic drugs unaltered by vinpocetine in mouse model of epilepsy
    Autorzy:
    Borowicz, K.K.
    Swiader, M.
    Banach, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/3020.pdf
    Data publikacji:
    2007
    Wydawca:
    Instytut Medycyny Wsi
    Źródło:
    Journal of Pre-Clinical and Clinical Research; 2007, 01, 1
    1898-2395
    Pojawia się w:
    Journal of Pre-Clinical and Clinical Research
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Effects of fluoxetine on the anticonvulsant action of valproate and ethosuximide in mouse model of myoclonic convulsions
    Autorzy:
    Borowicz, K.K.
    Piskorska, B.
    Stepniak, B.
    Czuczwar, S.J.
    Powiązania:
    https://bibliotekanauki.pl/articles/50030.pdf
    Data publikacji:
    2012
    Wydawca:
    Instytut Medycyny Wsi
    Opis:
    Depression is becoming a growing problem in rural areas. This psychiatric disorder often accompanies epilepsy. The aim of this study was to assess the influence of fluoxetine (FXT), a commonly used antidepressant, on the protective action of two conventional antiepileptic drugs: ethosuximide (ETX) and valproate (VPA), against pentylenetetrazole (PTZ)-induced convulsions in mice. Motor coordination and long-term memory deficits induced by FXT, antiepileptic drugs alone and in combinations with FXT were assessed in the chimney test and passive-avoidance task, respectively. Brain concentrations of ETX and VPA were measured by immunofluorescence. Obtained results indicate that FXT at the dose of 15 mg/kg (ip, 30 min before the test) significantly increased the threshold for clonic convulsions. The antidepressant drug at lower doses remained ineffective in this respect. Moreover, FXT at the highest subprotective dose (10 mg/kg, ip) markedly enhanced the anticonvulsant effects of VPA, but not of ETX, against PTZ-induced seizures. The interaction between FXT and VPA seems to be pharmacodynamic because the antidepressant drug did not alter the brain concentration of VPA. With regard to adverse effects, FXT, VPA, ETX, and the combinations of FXT with antiepileptic drugs, did not impair motor coordination and long-term memory in mice. In conclusion, the combination of FXT with VPA may be advantageous in the treatment of myoclonic epilepsy, and therefore it should be recommended for further study in clinical conditions.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2012, 19, 3
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Tourist maps - definition, types and contents
    Autorzy:
    Jancewicz, K.
    Borowicz, D.
    Powiązania:
    https://bibliotekanauki.pl/articles/92418.pdf
    Data publikacji:
    2017
    Wydawca:
    Oddział Kartograficzny Polskiego Towarzystwa Geograficznego
    Tematy:
    tourism
    tourist maps
    orientation
    navigation maps
    Opis:
    Tourist maps are one of the most common groups of cartographic documents. Their variety in terms of content, subject matter and publication titles is a result of growing popularity of diverse forms of tourism activity. The aim of the authors of this article is to demonstrate issues related to tourist maps, including their variety in relation to contemporary forms of tourism. As tourist maps are constantly developing, the authors decided to propose a classification of tourist maps which is adequate from the point of view of the types of maps we currently distinguish. Taking into consideration the aim and type of tourism, the maps were divided into the following sub-groups: maps for sightseeing tourism, qualified tourism, and other tourism, as well as tourist city maps, and maps prepared for promotion and advertising of tourism. The first there categories were further divided into more detailed sub-categories and each of them was described briefly in terms of its content. The classification of maps based on their scales and form of content presentation was also included. The authors attempted also to define the concept of “tourist map” itself. The authors defined it as a geographic representation of an area presented on a plane, in accordance with specific mathematical rules, which should include topographic contents, information about tourist attractions of a given area, its tourist and complementary infrastructure, presented with the help of conventional signs, in a matter appropriate for the scale of the map and its intended use. Contributing to the discussion on the place of tourist map in the general classification of maps, the article distinguishes not only general-geographic maps and thematic maps, but also orientation and navigation maps. This terms covered tourist maps, road maps, and navigation maps: sailing, sea, aerial and city maps. They consist a group of maps in which the functions they play determine their informational content and their form of cartographic presentation. However, unlike on thematic maps, where the general geographic content is merely a background for presentation of the theme-related phenomena, the geographic content is essential in case of tourist maps. It is precisely the general geographic content which is primarily responsible for communicating information which is meant to be used for orientation and navigation purposes.
    Źródło:
    Polish Cartographical Review; 2017, 49, 1; 27-41
    2450-6974
    Pojawia się w:
    Polish Cartographical Review
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Analysis of the influence of a metha-type metaphysical stem on biomechanical parameters
    Autorzy:
    Pozowski, A.
    Ścigała, K.
    Kierzek, A.
    Paprocka-Borowicz, M.
    Kuciel-Lewandowska, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/307293.pdf
    Data publikacji:
    2013
    Wydawca:
    Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
    Tematy:
    metaphysial stem
    osteointegration
    primary stability
    secondary stability
    stem loosening
    finite element method
    trwałość
    metoda elementów skończonych
    biomechanika
    Opis:
    The full postoperative loading of the limb is possible if patients are properly selected and qualified for hip arthroplasty and the requirements as to the proper position of the metaphysial stem are met. The lack of precision, and patient qualification which does not satisfy the fixed criteria may result in stem setting inconsistent with the assumptions. An analysis based on the finite element method (FEM) will enable one to find out how to plan the magnitude of operated joint loading on the basis of the position of the stem in the postoperative radiograph. By analyzing the distribution of bone tissue deformations one can identify the zones where the spongy bone is overloaded and determine the strain level in comparison with the one determined for a model of the bone with the stem in proper position. On the basis of the results obtained one can estimate the range of loads for the operated limb, which will not result in the loss of the stem’s primary stability prior to obtaining secondary stability through osteointegration. Moreover, an analysis of the formation of bone structures around the stem showed that the incorrect setting of a Metha-type stem may lead to the initiation of loosening.
    Źródło:
    Acta of Bioengineering and Biomechanics; 2013, 15, 2; 13-20
    1509-409X
    2450-6303
    Pojawia się w:
    Acta of Bioengineering and Biomechanics
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Evaluation of serum cytokine levels in recurrent airway obstruction
    Autorzy:
    Niedzwiedz, A.
    Borowicz, H.
    Kubiak, K.
    Nicpon, J.
    Skrzypczak, P.
    Jaworski, Z.
    Cegielski, M.
    Powiązania:
    https://bibliotekanauki.pl/articles/31728.pdf
    Data publikacji:
    2016
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Opis:
    Recurrent airway obstruction (RAO) represents a serious health problem and is traditionally classified as an allergic disease, where contact with an antigen can induce clinical airway inflammation, bronchial hyper-responsiveness and reversible airway obstruction. Previous studies have demonstrated the presence of the Th2 response in the lungs of human patients with asthma and horses with heaves. These cells are involved in the production of cytokines which regulate the synthesis of immunoglobulins. 40 horses were evaluated: 30 horses with RAO and 10 healthy animals. The expression levels of interferon-alpha 1 (IFN-α1), interferon-gamma (IFN-γ), interleukin-1β, (IL-1β), IL-2, IL-4, IL-13 and tumor necrosis factor alpha (TNF-α) were measured in the serum obtained from control and RAO-susceptible horses during crisis. In all the patients, serum cytokine levels were detected. Serum median IL-13 and IFN-γ levels were significantly higher in RAO-affected horses than in the healthy group (p < 0.001). The serum median IFN-α1, IL-1β, IL-2, IL-4, and TNF-α levels were similar in both groups. These results indicate a low variability of the levels of cytokines and a high frequency of their detection in serum samples from horses with RAO. Immune mechanisms involved in equine RAO are more complex than those defined by a simple Th1/Th2 dichotomy.
    Źródło:
    Polish Journal of Veterinary Sciences; 2016, 19, 4
    1505-1773
    Pojawia się w:
    Polish Journal of Veterinary Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Extent of protective or allergy-inducing effects in cats and dogs
    Autorzy:
    Krzych-Fałta, E.
    Furmanczyk, K.
    Piekarska, B.
    Raciborski, F.
    Tomaszewska, E.
    Walkiewicz, A.
    Samel-Kowalik, P.
    Borowicz, J.
    Namysłowski, A.
    Smoliński, B.K.
    Powiązania:
    https://bibliotekanauki.pl/articles/2081716.pdf
    Data publikacji:
    2018
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    allergic diseases
    cat and dog allergens
    risk factors
    Opis:
    Objective. The study aimed to assess the effect of fur-bearing pets, including cats and dogs, on the health of individuals with allergic conditions. Materials and method. The study group comprised 18,617 individuals (16,562 from urban and 2,055 from rural areas). The tool used in the study was the European Community Respiratory Health Survey (ECRHS) and International Study of Asthma and Allergies in Childhood (ISAAC) study questionnaire, adapted to European conditions (Middle and Eastern Europe) and used as part of the study Implementation of a System for the Prevention and Early Detection of Allergic Diseases in Poland. Results. The factors determining the keeping of fur-bearing pets in a household included a larger living space and the number of cigarettes smoked, which were observed especially in urban settings. The keeping of fur-bearing animals in rural areas acts preventively against allergic conditions, while in urban areas, these animals were a factor clearly aggravating symptoms of bronchial asthma – the risk of cough (OR 1.921; CI 10–3.36; P=0.02) and wheezing (OR 2.60; CI 1.22–5.54; P=0.01). Conclusion. Fur-bearing animals kept in rural settings exhibit preventive effects on the development of allergies; whereas in urban areas they exacerbate allergic symptoms, especially the symptoms of bronchial asthma.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2018, 25, 2; 268-273
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Condition of mineralized tooth tissue in a population of 15-year-old adolescents living in a region of Ukraine with slightly exceeded fluorine concentration in the water
    Autorzy:
    Bachanek, T.
    Hendzel, B.
    Wolańska, E.
    Samborski, D.
    Jarosz, Z.
    Pitura, K.M.
    Dzida, K.
    Podymniak, M.
    Tymczyna-Borowicz, B.
    Niewczas, A.
    Shibynskyy, V.
    Zimenkovsky, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/2085118.pdf
    Data publikacji:
    2019
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    tooth tissue
    fluorine
    chemical composition of water
    Opis:
    Introduction. Fluorine is a common element in nature; however, the difference between a beneficial dose and a toxic dose for the organisms is small. The main source of fluoride for humans is water in addition to food. Objective. The aim of this study was to estimate the degree of severity of pathological changes, namely, caries or fluorosis, in the mineralized tooth tissue of 15-year-old adolescents with respect to their hygienic and nutritional habits, and the content of fluorine in drinking water, soil and plant products. Materials and method. 100 adolescents aged 15 from schools in Sosniłka, L’viv region, were examined. The condition of mineralized tooth tissue was evaluated by the caries severity, expressed by the mean number D3MFT, caries frequency and value of the SIC index. Fluorine in plant material and soil were determined according to the PN-G-04543:1982 standard, and water according to the PN-EN ISO 10304 – 1: 2009+ AC: 2012 standard. Results. Severity of caries disease expressed by the D3MFT number in the examined group of 15-year-olds was 3.39; in the group of girls – 3.08, and in the group of boys – 3.76. In the examined group, the average number of teeth with fluorosis was 7.59. Value of the SIC index among the examined population of students (n-31) was 6.26: 5.89 (n-18) for girls and 7.31 (n-13) for boys. Fluorine concentration in the water was 0.78 – 1.25(mg·dm-3). In the soil, it also did not vary across the sampled areas and amounted, on average, to 176 mg·dm-3. The biggest fluorine content noted in the dry mass of beetroots was 3.50 (mg F· kg), and the lowest – 3.34 (mg F· kg). Conclusions. Close to optimal fluorine content lowers caries severity and frequency of fluorosis. Optimal fluorine content in drinking water and food does not require additional diet supplementation
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2019, 26, 4; 623-629
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Risk factors of postural defects in children at school age
    Autorzy:
    Latalski, M.
    Bylina, J.
    Fatyga, M.
    Repko, M.
    Filipovic, M.
    Jarosz, M.J.
    Borowicz, K.B.
    Matuszewski, L.
    Trzpis, T.
    Powiązania:
    https://bibliotekanauki.pl/articles/52145.pdf
    Data publikacji:
    2013
    Wydawca:
    Instytut Medycyny Wsi
    Opis:
    Introduction and objective: Postural defects increasingly more often concern children and adolescents at school age. The lack of prophylaxis and neglecting adequate procedures may lead to limitations of physical and motor abilities, back pain, or the development of severe spinal deformities. Recognition of the risk factors conducive to the occurrence of the disorder allows the creation of adequate conditions for the psychomotor development of children, as well as the elaboration and implementation of specified educational schemes directed at schools and parents. The study concerned determination of the risk factors for the development of postural defects in school age children. Material and methods: The study was conducted by means of a diagnostic survey. The study group covered 380 children aged 14 (175 girls (46.1%) and 205 boys (53.9%)) – selected at random from schools in eastern Poland and the Czech Republic. The significance of the relationships between variables was investigated by means of chi-square test for independence. The differences between the empirical and theoretical sample distribution was examined by means of chi-square goodnessof- fit test. The significance level was set at p=0.05. Results: The BMI in the population examined was 20.2, on average (from 14–39). Respondents living in rural areas and small towns constituted 57.63% of the study group, while inhabitants of medium-size and large cities – 42.37%. The majority of children in the study had been previously examined for the occurrence of postural defects (74.2%), whereas nearly every tenth child had never undergone such an examination. As many as 16.3% of adolescents did not know whether they had ever participated in a screening test. A defect was detected in 14.7% of children, in 56.6% no asymmetry was detected, while approximately 30% were not aware if their body posture was normal or not. Conclusions: 1. There is a relationship between physical activity of the child and the occurrence of postural defects. 2. There is a relationship between the economic standard of the family and awareness of own state of health. 3. There is a need for the creation of a system of education for parents and children concerning postural defects and risks resulting from these defects.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2013, 20, 3
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-15 z 15

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