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Wyświetlanie 1-2 z 2
Tytuł:
Risk Factors for Wound Dehiscence after Laparotomy – Clinical Control Trial
Autorzy:
Kenig, Jakub
Richter, Piotr
Żurawska, Sabina
Lasek, Anna
Zbierska, Katarzyna
Nowak, W.
Powiązania:
https://bibliotekanauki.pl/articles/1396927.pdf
Data publikacji:
2012-12-01
Wydawca:
Index Copernicus International
Tematy:
dehiscence
risk factors
Opis:
Described in the literature dehiscence rate in the adult population is 0.3-3.5%, and in the elderly group as much as 10%. In about 20-45% evisceration becomes a significant risk factor of death in the perioperative period. The aim of the study was to identify the main risk factors for abdominal wound dehiscence in the adult population. Material and methods. The study included patients treated in the 3rd Department of General Surgery, Jagiellonian University Collegium Medicum in Cracow in the period from January 2008 to December 2011, in which at that time laparotomy was performed and was complicated by wound dehiscence in the postoperative period. For each person in a research group, 3-4 control patient were selected. Selection criteria were corresponding age (± 2-3 years), gender, underlying disease and type of surgery performed. Results. In 56 patients (2.9%) dehiscence occurred in the postoperative period with 25% mortality. The group consisted of 37 men and 19 women with the mean age of 66.8 ± 12.6 years. Univariate analysis showed that chronic steroids use, surgical site infection, anastomotic dehiscence/fistula in the postoperative period and damage to the gastrointestinal tract are statistically significant risk factors for dehiscence. Two first of these factors occurred to be independent risk factors in the multivariate analysis. In addition, due to the selection criteria, a group of risk factors should also include male gender, emergency operation, midline laparotomy, colorectal syrgery and elderly age (> 65 years). Logistic regression analysis did not show that a particular surgeon, time of surgery or a particular month (including holiday months) were statistically significant risk factor for dehiscence. Conclusions. Wound dehiscence is a serious complication with relatively small incidence but also high mortality. Preoperative identification of risk factors allows for a more informed consent before patient’s treatment and to take measures to prevent or minimize the consequences of complication associated with it.
Źródło:
Polish Journal of Surgery; 2012, 84, 11; 565-573
0032-373X
2299-2847
Pojawia się w:
Polish Journal of Surgery
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Characteristics of CRY1AB Protein From Bioinsecticides and Insect Resistant GM Crops
Autorzy:
Żmijewska, Ewelina
Linkiewicz, Anna
Żurawska-Zajfert, Magdalena
Grelewska-Nowotko, Katarzyna
Sowa, Sławomir
Zimny, Janusz
Powiązania:
https://bibliotekanauki.pl/articles/2199646.pdf
Data publikacji:
2016-06-20
Wydawca:
Instytut Hodowli i Aklimatyzacji Roślin
Tematy:
biological insecticide
Cry1Ab protein
Cry protein mode of action
GM plant
Opis:
Biological insecticides are an effective method used in plant protection. One of the most widely used active substances in biological insecticides is Cry1Ab protein, which is toxic for lepidopteran insects. This protein is produced during bacterial sporulation by Bacillus thuringiensis. Other sources of Cry1Ab protein are genetically modified plants (GM) with expression of cry1Ab gene. Cry1Ab protein in both bioinsecticides and GM plants is present in the form of protoxin, which requires activation by enzymatic treatment in the gut of susceptible insects. So far, Cry1Ab mode of action is not fully understood, but there are 3 main concepts describing it. Two of them assume that a toxic protein after binding to receptors in the insect gut penetrates into the cells, causing pore formation in the gut, which leads to the death of the sensitive insect. In the third model Cry1Ab toxic action is a result of toxin-induced chemical processes initiating a cell death pathway. This work describes the structure and mode of action of Cry1Ab protein, present in biological insecticides and genetically modified plants.
Źródło:
Plant Breeding and Seed Science; 2016, 73; 25-37
1429-3862
2083-599X
Pojawia się w:
Plant Breeding and Seed Science
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-2 z 2

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