Wszystkie pola: protein synthesis in vitro - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: An inhibitory effect of cyclic nucleotide-independent protein kinases on protein synthesis in vitro
Autorzy:: Jakubowicz, Teresa
Paleń, Emilia
Szyszka, Ryszard
Kudlicki, Wiesław
Gąsior, Eugeniusz
Powiązania:: https://bibliotekanauki.pl/articles/1046110.pdf
Data publikacji:: 1982
Wydawca:: Polskie Towarzystwo Biochemiczne
Źródło:: Acta Biochimica Polonica; 1982, 29, 1-2; 45-55
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

Artykuł

Skocz do pozycji: 2.

Tytuł:: Inhibitory effects of pentamidine analogues on protein biosynthesis in vitro.
Autorzy:: Bielawski, Krzysztof
Galicka, Anna
Bielawska, Anna
Średzińska, Krystyna
Powiązania:: https://bibliotekanauki.pl/articles/1044401.pdf
Data publikacji:: 2000
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: amidine
elongation factors
protein synthesis in vitro
DAPI
Opis:: Pentamidine despite its rather high toxicity, is currently in clinical use. For development of new drugs of this type it is important to know the mechanism of their action. Two new amidines (I and II) and 4',6-diamidino-2-phenylindole (DAPI) were found in preliminary experiments to inhibit protein synthesis in vitro in the cell-free rat liver system. The three compounds differed in the precise mode of action. The inhibitory effect of I on the activity of the eukaryotic elongation factor eEF-2 and ribosomes seems to suggest that the binding site of eEF-2 on the ribosome was blocked by this compound. eEF-2 has been identified as the primary target of II and eEF-1 as the primary target of DAPI in the system studied.
Źródło:: Acta Biochimica Polonica; 2000, 47, 1; 113-120
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

Artykuł

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