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Wyszukujesz frazę "bilinski, R." wg kryterium: Wszystkie pola


Wyświetlanie 1-3 z 3
Tytuł:
Competition between plants from adjacent plots in field trial with winter oilseed rape (Brassica napus L.). 1. Effects of plant competition and variability of soil fertility inside the block
Konkurencja pomiędzy roślinami z sąsiadujących poletek w doświadczeniu polowym z rzepakiem ozimym. 1. Skutki konkurencji roślin i zmienności żyzności gleby wewnątrz bloku
Autorzy:
Krzymanski, J.
Krotka, K.
Ogrodowczyk, M.
Wos, H.
Bilinski, R.
Budzianowski, G.
Zagierska, J.
Powiązania:
https://bibliotekanauki.pl/articles/833370.pdf
Data publikacji:
2012
Wydawca:
Instytut Hodowli i Aklimatyzacji Roślin
Tematy:
competition
plant
adjacent plant
field trial
winter oilseed rape
oilseed rape
Brassica napus
plant competition
plant variation
soil fertility
seed yield
soil variability
regression analysis
variation analysis
regression coefficient
Źródło:
Rośliny Oleiste - Oilseed Crops; 2012, 33, 1
1233-8273
Pojawia się w:
Rośliny Oleiste - Oilseed Crops
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Epigenetic regulation in drug addiction
Autorzy:
Bilinski, P.
Wojtyla, A.
Kapka-Skrzypczak, L.
Chwedorowicz, R.
Cyranka, M.
Studzinski, T.
Powiązania:
https://bibliotekanauki.pl/articles/50469.pdf
Data publikacji:
2012
Wydawca:
Instytut Medycyny Wsi
Opis:
The interaction between environmental signals and genes has now taken on a clear molecular form as demonstrated by stable changes in chromatin structure. These changes occur through activation or repression of specific gene programmes by a combination of chromatin remodelling, activation and enzymatic modification of DNA and histones as well as nucleosomal subunit exchange. Recent research investigating the molecular mechanisms controlling drug-induced transcriptional, behavioural and synaptic activity has shown a direct role for chromatin remodelling – termed as epigenetic regulation – of neuronal gene programmes and subsequent addictive behaviour arising from it. Recent data suggest that repeated exposure to certain drugs promotes changes in levels of histone acetylation, phosphorylation and methylation, together with alterations in DNA methylation levels in the neurons of the brain reward centre, localised in the Nucleus Accumbens (NAc) region of the limbic system. The combination of acetylating, phosphorylating and methylating H3 and H4 histone tails alter chromatin compaction thereby promoting altered levels of cellular gene expression. Histone modifications, which weaken histone interaction with DNA or that promote recruitment of transcriptional activating complexes, correlate with permissive gene expression. Histone deacetylation, (which strengthen histone: DNA contacts), or histone methylation, (which recruits repressive complexes to chromatin), promote a state of transcriptional repression. Using animal models, acute cocaine treatment increases H4 acetylation at acutely regulated gene promoters, whereas H3 acetylation appears to predominate at chronically induced promoters. Chronic cocaine and alcohol treatment activate and repress many genes such as FosB, Cdk5, and Bdnf, where their dysregulation, at the chromatin level, contribute to the development and maintenance of addiction. Following drug exposure, it is still unknown, howver, how long these changes in chromatin structure persist in affecting neuronal function, but some do so for life.
Źródło:
Annals of Agricultural and Environmental Medicine; 2012, 19, 3
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Comparison of American guidelines for field triage and Polish criteria as qualification to a trauma center
Autorzy:
Nowakowski, J.
Nowakowski, R.
Biliński, P.
Nowak, B.
Wojciechowski, P.
Dworzyński, M.
Golis-Gucwa, M.
Timler, W.
Timler, M.
Timler, D.
Powiązania:
https://bibliotekanauki.pl/articles/2085003.pdf
Data publikacji:
2019
Wydawca:
Instytut Medycyny Wsi
Tematy:
trauma
guidelines
decision making
emergency medical services
EMS
injury
triage
ISS
multiple organ injuries
trauma center
Opis:
Introduction. Trauma is the third cause of death among the general population in Poland, and the first in people aged 1–44 years. Trauma centers are hospitals dedicated to treating patients with multiple organ injuries, in a complex way that endeavours to ensure a lower mortality rate, shorter hospital stay and better outcomes if the patients are transferred to such a center. Worldwide, there are many models on how to treat a trauma patient, but them to be qualified for the procedure, the selection of potential patients is crucial. Objective. The aim of the study was to compare the Polish model for qualification to a trauma center and American Guidelines for Field Triage. Materials and method. Retrospective analysis of medical documentation recorded between 1 January 2014 – 31 December 2014 was undertaken. The study concerned trauma patients admitted to the Emergency Department of the Regional Trauma Center at the Copernicus Memorial Hospital in Łódź, Poland. Inclusion criterion was initial diagnosis ‘multiple-organ injury’ among patients transported by the Emergency Medical Service (EMS). Results. In the period indicated, 3,173 patients were admitted to the Emergency Department at the Copernicus Memorial Hospital. From among them, 159 patients were included in the study. Only 13.2% of the patients fulfilled the Polish Qualification Criteria to Trauma Center in comparison to 87.4% who fulfilled the American Guidelines for Field Triage. Conclusions. Polish qualification criteria do not consider the large group of patients with severe injuries (ISS>15), but indicate patients with minimal chance of survival. Polish criteria do not consider the mechanism of injury, which is a relevant predictive indicator of severe or extremely severe injuries (ISS>15). Further studies should be undertaken to improve the qualification and treatment of trauma patients in Poland.
Źródło:
Annals of Agricultural and Environmental Medicine; 2019, 26, 3; 479-482
1232-1966
Pojawia się w:
Annals of Agricultural and Environmental Medicine
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-3 z 3

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