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    Wyświetlanie 1-3 z 3
    Tytuł:
    Acute Ischemia of the Lower Extremity During Renal Transplantation – Case Report
    Autorzy:
    Krupiński, Radosław
    Wolski, Andrzej
    Bicki, Jacek
    Rudzki, Sławomir
    Powiązania:
    https://bibliotekanauki.pl/articles/1395773.pdf
    Data publikacji:
    2014-08-01
    Wydawca:
    Index Copernicus International
    Tematy:
    renal transplantation
    acute limb ischemia
    Opis:
    Acute ischemia of the lower extremity during renal transplantation is a rare complication of such procedure, but if it occurs, requires immediate vascular repair. This paper present one case of such complication that occurred during many years of renal transplantation at the Department of General and Transplantation Surgery, Public Hospital No. 4 in Lublin. Furthermore, a method to solve this problem is presented.
    Źródło:
    Polish Journal of Surgery; 2014, 86, 8; 374-376
    0032-373X
    2299-2847
    Pojawia się w:
    Polish Journal of Surgery
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Evaluation of the knowledge of the issues related to human papillomavirus infections within young women
    Autorzy:
    Węgorowski, Paweł
    Michalik, Joanna
    Turkowska, Karolina
    Stanisławek, Andrzej
    Wolski, Dariusz
    Bieńko, Marek
    Radzki, Radosław P.
    Powiązania:
    https://bibliotekanauki.pl/articles/454862.pdf
    Data publikacji:
    2018
    Wydawca:
    Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
    Tematy:
    HPV virus
    human papillomavirus cervical cancer
    Opis:
    Introduction. Human papillomavirus infections are frequent in on average 9% to 13% of the female population, and the risk of infection throughout life exceeds 50%. The HPV virus causes changes in the mucous membranes and the skin of the genital area in both women and men. Aim. This paper presents epidemiology, prophylaxis, diagnostics and treatment of HPV and cervical cancer infections. In addition, the knowledge of issues related to human papillomavirus infection among young women was assessed. Materials and methods. The diagnostic survey method was used to carry out the research. The research tool was a questionnaire of own authorship consisting of 41 questions. The research group consisted of 240 women. The research was carried out from June to September 2016 at the Chodźki Medical Center and the Luxmed facility in Lublin. Results. There is a relationship between the education of the respondents and their knowledge about the human papillomavirus infection. The studies did not show a significant relationship between the self-esteem of the studied women and whether they were vaccinated against the HPV virus (Chi-square = 0.362, p = 0.547). Conclusions. The general level of knowledge on issues related to human papillomavirus infection among young women is at the secondary level. A higher level of general knowledge was shown by women with better education, related to the medical and biological sciences. The self-assessment of the respondents coincides with the general knowledge, based on detailed questions, on issues related to HPV infection. Promoting knowledge about HPV infection is unsatisfactory
    Źródło:
    European Journal of Clinical and Experimental Medicine; 2018, 4; 308-316
    2544-2406
    2544-1361
    Pojawia się w:
    European Journal of Clinical and Experimental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Pre-analytical-related variability influencing serum peptide profiles demonstrated in a mass spectrometry-based search for colorectal and prostate cancer biomarkers
    Autorzy:
    Karczmarski, Jakub
    Rubel, Tymon
    Mikula, Michal
    Wolski, Jan
    Rutkowski, Andrzej
    Zagorowicz, Edyta
    Dadlez, Michal
    Ostrowski, Jerzy
    Powiązania:
    https://bibliotekanauki.pl/articles/1039544.pdf
    Data publikacji:
    2013
    Wydawca:
    Polskie Towarzystwo Biochemiczne
    Tematy:
    mass spectrometry; peptidome; serum; cancer; fibrinopeptide A
    apolipoprotein A-IV
    Opis:
    Although the degradome, which comprises proteolytic fragments of blood proteins, presents a potential source of diagnostic biomarkers, studies on cancer peptide biomarkers have provided inconsistent conclusions. In the present study, we reevaluated the usefulness of serum degradome analyses for searching peptide cancer biomarker candidates. Particular attention was paid to pre-analytical factors influencing the variability of determined peptide levels, including clotting time and control group selection. Studies were conducted on 44 and 86 serum samples collected from cancer patients and healthy individuals, respectively, using liquid chromatography electrospray ionization mass spectrometry (LC-ESI-MS)-based analyses. We identified 1373 unique peptides, nearly 40% of which originated from five blood proteins: fibrinogen alpha chain, apolipoprotein A-IV (APOA4), complement C3, apolipoprotein A-I, and alpha-1-antitrypsin. A set of 118 and 88 peptides exhibited highly significant differences (adjusted p-value ≤ 0.01 and fold change ≥ 2) in pair-wise comparisons of control vs. prostate cancer and control vs. colorectal cancer, respectively, with 37 peptides displaying a consistent direction of change for these pair-wise comparisons. The levels of 67 peptides differed significantly in serum samples collected from healthy individuals immediately prior to colonoscopy and those who underwent colonoscopic examination at least four weeks earlier. Of them, 49 peptides originated from APOA4. Whereas earlier studies, including ours, have utilized fragments of fibrinopeptide A (FPA) to distinguish cancer from healthy cases, here we show that their absolute abundance is a sensitive indicator of clotting time. These observations may have implications for future serum peptidome studies since these issues have not previously been recognized.
    Źródło:
    Acta Biochimica Polonica; 2013, 60, 3; 417-425
    0001-527X
    Pojawia się w:
    Acta Biochimica Polonica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-3 z 3

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