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    Wyświetlanie 1-12 z 12
    Tytuł:
    Conformational analysis of fragment of human Pin1 ww domain: influence of charged amino-acid residues on β-hairpin structure
    Autorzy:
    Makowska, J.
    Uber, D.
    Żmudzińska, W.
    Chmurzyński, L.
    Powiązania:
    https://bibliotekanauki.pl/articles/1935818.pdf
    Data publikacji:
    2014
    Wydawca:
    Politechnika Gdańska
    Tematy:
    peptide conformation
    β-hairpin
    hPin1 protein
    NMR
    Opis:
    We examined the effect of like-charged residues on the conformation of an original nine amino-acid-residue fragment of the human Pin1 WW domain (hPin1) with the following sequence: Ac-Arg-Met-Ser-Arg-Ser-Ser-Gly-Arg-Val-NH 2 (U9). This was facilitated by CD and NMR spectroscopic measurements, and molecular dynamics calculations. Our ear lier studies suggested that the presence of like-charged residues at the end of a short polypeptide chain composed of nonpolar residues could induce a chain reversal. For the U9 peptide, canonical MD simulations with NMR -derived restraints demonstrated the presence of ensembles of structures with a tendency to form a β -chain reversal. Additionally, thermal stabilities of the peptide under study were measured using differential scanning calorimetry ( DSC ). The estimated well defined phase transition point showed that conformational equilibria in the U9 peptide were strongly dependent on temperature.
    Źródło:
    TASK Quarterly. Scientific Bulletin of Academic Computer Centre in Gdansk; 2014, 18, 4; 343--349
    1428-6394
    Pojawia się w:
    TASK Quarterly. Scientific Bulletin of Academic Computer Centre in Gdansk
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Probing of Cu2+ ions binding to A β (5−16) peptide using ITC measurements and MD simulations
    Autorzy:
    Makowska, J.
    Żmudzińska, W.
    Wyrzykowski, D.
    Brzozowski, K.
    Zblewska, H.
    Chmurzyński, L.
    Powiązania:
    https://bibliotekanauki.pl/articles/1938620.pdf
    Data publikacji:
    2016
    Wydawca:
    Politechnika Gdańska
    Tematy:
    A β (5 − 16) fragments
    metal-peptide binding
    isothermal titration calorimetry
    molecular dynamics simulations
    Opis:
    It is shown that probably three residues: His6, His14 and His16 in the original sequence A β (1−42) serve as metal-binding sites for Cu2+ions. On the other hand, there is a possibility that only one of them plays a crucial role in the formation of the{A β (1-42)-Cu2+} complex. The isothermal titration calorimetry (ITC) measurements supported by molecular dynamic simulation (MD) with the NMR-derived restrains were used to investigate the interactions of Cu2+ with A β(5-16), a fragment of the A β(1-42) protein, with the following sequence: Ac-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-NH2, termed HZ1. The conditional thermodynamic parameters suggest that the formation of the Cu2+-HZ1 complex is both an enthalpy and entropy driven process under the experimental conditions. The studies presented here (after comparison with our previous results) show that the affinity of peptides to copper metal ions depends on two factors: the primary structure (amino acid composition) and the shape of the peptide conformation adopted.
    Źródło:
    TASK Quarterly. Scientific Bulletin of Academic Computer Centre in Gdansk; 2016, 20, 4; 409-416
    1428-6394
    Pojawia się w:
    TASK Quarterly. Scientific Bulletin of Academic Computer Centre in Gdansk
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Albinism – common phenomenon during cereal androgenesis
    Autorzy:
    Makowska, K.
    Zimny, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/951185.pdf
    Data publikacji:
    2015
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    androgenesis
    doubled haploid
    albinism
    chloroplast
    photosynthesis
    genetic research
    Źródło:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology; 2015, 96, 1
    0860-7796
    Pojawia się w:
    BioTechnologia. Journal of Biotechnology Computational Biology and Bionanotechnology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Detection and Recognition of Environmental Sounds by Musicians and Non-Musicians
    Autorzy:
    Miśkiewicz, A.
    Rościszewska, T.
    Żera, J.
    Majer, J.
    Okoń-Makowska, B.
    Powiązania:
    https://bibliotekanauki.pl/articles/176313.pdf
    Data publikacji:
    2018
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    environmental sounds
    detection threshold
    recognition threshold
    Opis:
    The article reports three experiments conducted to determine whether musicians possess better ability of recognising the sources of natural sounds than non-musicians. The study was inspired by reports which indicate that musical training develops not only musical hearing, but also enhances various non-musical auditory capabilities. Recognition and detection thresholds were measured for recordings of environment al sounds presented in quiet (Experiment 1) and in the background of a noise masker (Experiment 2). The listener’s ability of sound source recognition was inferred from the recognition-detection threshold gap (RDTG) defined as the difference in signal level between the thresholds of sound recognition and sound detection. Contrary to what was expected from reports of enhanced auditory abilities of musicians, the RDTGs were not smaller for musicians than for non-musicians. In Experiment 3, detection thresholds were measured with an adaptive procedure comprising three interleaved stimulus tracks with different sounds. It was found that the threshold elevation caused by stimulus interleaving was similar for musicians and non-musicians. The lack of superiority of musicians over non-musicians in the auditory tasks Explorer in this study is explained in terms of a listening strategy known as casual listening mode, which is a basis for auditory orientation in the environment.
    Źródło:
    Archives of Acoustics; 2018, 43, 4; 581-592
    0137-5075
    Pojawia się w:
    Archives of Acoustics
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Isotope effects on selected physicochemical properties of nitromethane and 1-pentanol
    Autorzy:
    Makowska, A.
    Szydłowski, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/148594.pdf
    Data publikacji:
    2006
    Wydawca:
    Instytut Chemii i Techniki Jądrowej
    Tematy:
    deuterium
    isotope effects
    density
    viscosity
    speed of sound
    nitromethane
    1-pentanol
    Opis:
    Densities, kinematic viscosities, speed of sound and refractive indices of nitromethane and 1-pentanol and their deuterated derivatives CD3NO2 and C5H11OD were measured. The data obtained allowed to calculate molar volumes, dynamic viscosities, isentropic compressibilities and isobaric thermal expansion. Deuterium isotope effect on the selected physicochemical properties of both nitromethane and 1-pentanol has been determined. Large isotope effects characterizing density, viscosity and speed of sound are observed for nitromethane and much smaller for 1-pentanol. Isotope effects on molar volume are small both for nitromethane and 1-pentanol, but of the opposite sign. These observations are in agreement with the expectations.
    Źródło:
    Nukleonika; 2006, 51,suppl.2; 81-85
    0029-5922
    1508-5791
    Pojawia się w:
    Nukleonika
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The geodetic monitoring of the engineering structure - a practical solution of the problem in 3D space
    Autorzy:
    Filipiak-Kowszyk, D.
    Janowski, A.
    Kamiński, W.
    Makowska, K.
    Szulwic, J.
    Wilde, K.
    Powiązania:
    https://bibliotekanauki.pl/articles/106889.pdf
    Data publikacji:
    2016
    Wydawca:
    Politechnika Warszawska. Wydział Geodezji i Kartografii
    Tematy:
    displacement
    monitoring
    adjustment
    przemieszczenie
    monitorowanie
    dostosowanie
    Opis:
    The study raises the issues concerning the automatic system designed for the monitoring of movement of controlled points, located on the roof covering of the Forest Opera in Sopot. It presents the calculation algorithm proposed by authors. It takes into account the specific design and location of the test object. High forest stand makes it difficult to use distant reference points. Hence the reference points used to study the stability of the measuring position are located on the ground elements of the sixmeter-deep concrete foundations, from which the steel arches are derived to support the roof covering (membrane) of the Forest Opera. The tacheometer used in the measurements is located in the glass body placed on a special platform attached to the steel arcs. Measurements of horizontal directions, vertical angles and distances can be additionally subject to errors caused by the laser beam penetration through the glass. Dynamic changes of weather conditions, including the temperature and pressure also have a significant impact on the value of measurement errors, and thus the accuracy of the final determinations represented by the relevant covariance matrices. The estimated coordinates of the reference points, controlled points and tacheometer along with the corresponding covariance matrices obtained from the calculations in the various epochs are used to determine the significance of acquired movements. In case of the stability of reference points, the algorithm assumes the ability to study changes in the position of tacheometer in time, on the basis of measurements performed on these points.
    Źródło:
    Reports on Geodesy and Geoinformatics; 2016, 102; 1-14
    2391-8365
    2391-8152
    Pojawia się w:
    Reports on Geodesy and Geoinformatics
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The effect of storage on physicochemical properties of spray-dried milk, egg and milk-egg mixture
    Wpływ przechowywania na cechy fizykochemiczne mleka, jaj i mieszanki mleczno-jajowej w proszku
    Autorzy:
    Chudy, S.
    Pikul, J.
    Rudzinska, M.
    Makowska, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/36117.pdf
    Data publikacji:
    2015
    Wydawca:
    Polska Akademia Nauk. Instytut Agrofizyki PAN
    Opis:
    The aim of this work was to obtain a new spray-dried milk-egg mixture and to compare its physicochemical properties with the properties of whole milk powder and egg powder. The powders prepared were packaged in bags under air and vacuum and stored for 24 months. During storage all of the properties assayed (lightness, hydroxymethylfurfural, Maillard browning intensity, thiobarbituric acid reactive substances, solubility index, pH) deteriorated. The addition of milk to egg before drying improved the solubility of egg powder. Solubility of milk powder was higher than 2 cm3 in the twelfth month of storage. For this reason the powders retained their best qualities till the sixth month of storage. The kind of packaging had an influence on the quality of the products (vacuum packaging delayed the deterioration of powders).
    Celem pracy było wyprodukowanie nowych proszków mleczno-jajowych i porównanie ich właściwości fizykochemicznych z właściwościami pełnego mleka i jaja w proszku. Proszki zostały zapakowanie w woreczki z tworzywa sztucznego w otoczeniu powietrza oraz próżni i poddane przechowywaniu przez okres 24 miesięcy. Podczas przechowywania wszystkie oznaczane cechy uległy pogorszeniu (jasność, hydroksymettylofurfural, intensywno brązowienia, związki reagujące z kwasem tiobarbiturowym, indeks rozpuszczalności, pH). Dodatek mleka do jaj spowo-dował polepszenie rozpuszczalności proszku jajowego. W 12 miesiącu przechowywania rozpusz-czalność mleka w proszku była wyższa niż zalecenia (tj. >2 cm3 ). Z uwagi na ten fakt stwierdzono, że proszki zachowały swoje najlepsze cechy do 6 miesiąca przechowywania. Sposób pakowania miał statystycznie istotny wpływ na badane właściwości fizykochemiczne (pakowanie próżniowe opóźniało proces starzenia się proszków).
    Źródło:
    Acta Agrophysica; 2015, 22, 1
    1234-4125
    Pojawia się w:
    Acta Agrophysica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The Impact of Extrusion on the Biogas and Biomethane Yield of Plant Substrates
    Autorzy:
    Pilarski, K.
    Pilarska, A. A.
    Witaszek, K.
    Dworecki, Z.
    Żelaziński, T.
    Ekielski, A.
    Makowska, A.
    Michniewicz, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/952409.pdf
    Data publikacji:
    2016
    Wydawca:
    Polskie Towarzystwo Inżynierii Ekologicznej
    Tematy:
    extrusion
    lignocellulosic biomass
    anaerobic digestion
    biomethane yield
    economic balance
    Opis:
    The objective of the present work was to determine the effect of pretreatment by extrusion on the biogas and biomethane yield of lignocellulosic substrates such as maize silage and maize straw silage. The biogas yields of the substrates before and after treatment were compared. Moreover, energy efficiency of pretreatment by extrusion was analyzed in order to assess the applicability of the process in an agricultural biogas plant. Extrusion tests were carried out in a short single-screw extruder KZM-2 in which the length-to-diameter ratio of the screw was 6:1 and rotational speed was 200 rpm. The biogas yield tests of the plant substrates after extrusion were carried out in a laboratory scale, using 15 biofermenters operated in a periodic manner, at a constant temperature of 39°C (mesophilic digestion) and controlled pH conditions. The gas-emission analysis was performed using a certified gas analyzer from Geotech GA5000. Pretreatment by extrusion was observed to improve the quantity of methane generated: in terms of fresh matter for maize silage subjected to extrusion, the methane yield was 16.48% higher than that of the non-extruded silage. On the other hand, maize straw silage after extrusion gave 35.30% more methane than did the same, non-extruded, material. Differences in yields relative to dry organic matter are also described in this paper. Taking into account the amount of energy that is spent on pretreatment and the generated amount of methane, the energy balance for the process gives an idea of the economics of the operation. For maize silage, energy efficiency was lower by 13.21% (-553.2 kWh/Mg), in contrast to maize straw silage, where the increase in energy was 33.49% (678.4 kWh/Mg). The obtained results indicate that more studies on the pretreatment and digestion of maize silage are required in order to improve the efficiency of its use for making biogas. To fully utilize its potential, it is necessary to know thoroughly the effect of the extrusion process and of biogas production on energy efficiency at different conditions.
    Źródło:
    Journal of Ecological Engineering; 2016, 17, 4; 264-272
    2299-8993
    Pojawia się w:
    Journal of Ecological Engineering
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    PCR-RFLP-based molecular studies on inter-population variability in the crucian carp (Carassius carassius L.)
    Autorzy:
    Kempter, J.
    Panicz, R.
    Makowska, M.
    Metza, M.
    Keszka, S.
    Kielpinski, M.
    Sadowski, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/841729.pdf
    Data publikacji:
    2011
    Wydawca:
    Uniwersytet Szczeciński. Wydawnictwo Naukowe Uniwersytetu Szczecińskiego
    Tematy:
    PCR-RFLP method
    molecular study
    interpopulation variability
    carp
    crucian carp
    Carassius carassius
    Cyprinidae
    fish
    population genetics
    restriction enzyme
    Opis:
    Genetic variability of three sympatric crucian carp ( Carassius carassius ) populations from NW Poland was studied within a research project aimed at assessing the utility of those populations for stocking in inland waters. DNA samples were collected from 65 individuals. Restriction analysis was performed using 4 enzymes (HaeIII, HinfI, FspBI, TasI) of known restriction sites. The restriction pro files obtained were classified as belonging to a single haplotype (H-1). Selected DNA products were sequenced; the subsequent comparison made it possible to detect the presence of substi- tutions in the genome fragment analysed.
    Źródło:
    Zeszyty Naukowe Uniwersytetu Szczecińskiego. Acta Biologica; 2011, 18
    1230-3976
    Pojawia się w:
    Zeszyty Naukowe Uniwersytetu Szczecińskiego. Acta Biologica
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Modelling of carbon and nitrogen compounds removal from domestic wastewater in a modernized biological reactor
    Autorzy:
    Makowska, M.
    Jadanowski, S.
    Tränckner, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/207574.pdf
    Data publikacji:
    2018
    Wydawca:
    Politechnika Wrocławska. Oficyna Wydawnicza Politechniki Wrocławskiej
    Tematy:
    biological reactor
    domestic wastewater
    activated sludge process
    hybrid technology
    removal nitrogen
    reaktor biologiczny
    ścieki domowe
    proces osadu czynnego
    proces hybrydowy
    usuwanie azotu
    Opis:
    Upgrading concepts for the Bioblok MU200a wastewater treatment plant have been presented. The main goals were to achieve an effective nitrogen removal and reduce energy demand. The reference version has been presented, followed by two retrofitting options: introduction of intermittent aeration for alternating aerobic and anoxic conditions, additionally including a retrofitting option to a hybrid technology that combines advantages of activated sludge and biofilm. To design and assess both variants, the ASM3 model was used, running on the Simba# simulator. A rather complex biofilm model, necessary for the hybrid concept, was bypassed by installing a separate activated sludge process differing in terms of sludge age and disposal of its excess sludge to the reactor. In this way, favorable technological parameters for efficient wastewater treatment could be assessed. Both upgrading concepts can be recommended for their satisfactory treatment effectiveness, feasibility in existing plants and considerable energy savings. The significance of the modelled effects was statistically confirmed two-tailed Student’s t-test.
    Źródło:
    Environment Protection Engineering; 2018, 44, 4; 69-83
    0324-8828
    Pojawia się w:
    Environment Protection Engineering
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Treatment of wastewater from service areas at motorways
    Oczyszczanie ścieków z miejsc obsługi podróżnych przy autostradzie
    Autorzy:
    Makowska, M.
    Mazurkiewicz, J.
    Powiązania:
    https://bibliotekanauki.pl/articles/205279.pdf
    Data publikacji:
    2016
    Wydawca:
    Polska Akademia Nauk. Czytelnia Czasopism PAN
    Tematy:
    motorway service areas
    local treatment plants
    biofilters
    wastewater treatment
    facilities at transport routes
    miejsca obsługi podróżnych
    MOP
    natężenie ruchu
    autostrada A2
    oczyszczalnie lokalne
    biofiltr
    jakość ścieków
    Opis:
    This paper deals with wastewater treatment systems placed in motorway service areas (MSAs). In the years 2008-2009 eight of such facilities installed on the stretch of the A2 motorway between Poznań and Nowy Tomyśl were examined and analyzed. The system consists of a septic tank, a submerged aerated biofilter and an outflow filter. The volume of traffic on the highway was analyzed, the amount of water use was measured and peak factors were calculated. On this basis it was concluded that the inflows to the wastewater treatment systems in many cases exceeded the nominal design values. Based on the analysis of effluent quality it was found that the effects of plant operation in large part did not meet the requirements. It was found that the bioreactor aeration system and the design of the suspension separator (outflow filter) should be modified. One of the solutions was to use the soil-reed bed for wastewater treatment. The treatment of wastewater from the MSAs is a task that must take into account the unusual character of these facilities and the atypical quality of the effluent.
    Praca dotyczy systemów oczyszczania ścieków w Miejscach Obsługi Podróżnych (MOP) przy autostradach. Badano i analizowano 8 instalacji zamontowanych w MOP-ach przy autostradzie A2 między Poznaniem a Nowym Tomyślem. Systemy składają się z osadnika gnilnego, zanurzonego, napowietrzanego złoża biologicznego i filtra odpływowego. Analizowano natężenie ruchu na autostradzie, ilość zużywanej wody oraz jakość ścieków na wlocie i wylocie z bioreaktora. Na tej podstawie stwierdzono, że wielkość oczyszczalnie nie jest adekwatna do ilości i jakości dopływających ścieków. Stwierdzono, że jakość odpływu jest niezadowalająca oraz zaproponowano zmiany konstrukcyjne i technologiczne.
    Źródło:
    Archives of Environmental Protection; 2016, 42, 4; 80-89
    2083-4772
    2083-4810
    Pojawia się w:
    Archives of Environmental Protection
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Marcello Garzaniti, „Słowianie. Historia, kultury i języki” [„The Slavs. History, Cultures and Languages”], trans. J. Groblińska, K. Kowalik, A. Makowska-Ferenc, ed. Z.A. Brzozowska, P. Kręzel, J.M. Wolski, Wydawnictwo Uniwersytetu Łódzkiego, Łódź 2023, pp. 566
    Autorzy:
    Brzozowska, Zofia A.
    Kręzel, Piotr
    Powiązania:
    https://bibliotekanauki.pl/articles/31337803.pdf
    Data publikacji:
    2023
    Wydawca:
    Uniwersytet Łódzki. Wydawnictwo Uniwersytetu Łódzkiego
    Źródło:
    Studia Ceranea; 2023, 13; 784-785
    2084-140X
    2449-8378
    Pojawia się w:
    Studia Ceranea
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-12 z 12

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