Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Wyszukujesz frazę "tertiary structure" wg kryterium: Temat


Wyświetlanie 1-5 z 5
Tytuł:
Structural similarity of CheY-like proteins
Autorzy:
Banach, M.
Konieczny, L.
Roterman, I.
Powiązania:
https://bibliotekanauki.pl/articles/1938624.pdf
Data publikacji:
2016
Wydawca:
Politechnika Gdańska
Tematy:
hydrophobicity
tertiary structure
hydrophobic core
Opis:
The problem of structural similarity of polypeptide chains of low sequence similarity representing a similar 3D structural form has been the object of analysis of researchers engaged in the protein folding problem. Three homologous proteins of similar biological function with low sequence similarity are the objects of analysis presented in this paper. The structure of a hydrophobic core is used as the criterion for structural similarity assessment of these three proteins. The applied method allows recognition of differentiati on in topologically similar structures.
Źródło:
TASK Quarterly. Scientific Bulletin of Academic Computer Centre in Gdansk; 2016, 20, 4; 383-392
1428-6394
Pojawia się w:
TASK Quarterly. Scientific Bulletin of Academic Computer Centre in Gdansk
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
RNA dactyloscopy
Autorzy:
Gabryelska, Marta
Wyszko, Eliza
Barciszewski, Jan
Powiązania:
https://bibliotekanauki.pl/articles/1038740.pdf
Data publikacji:
2016
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
hammerhead ribozyme
RNA tertiary structure
fingerprint
Opis:
Despite the wealth of data on RNA secondary structure, conformational dynamics and tertiary structure in vitro and in vivo, predicting RNA biological activity in cellular environments remains difficult. Here, we present a comparison between in silico RNA fingerprinting and published experimental data that sheds light on efficient design of the hammerhead ribozyme molecules with a high intracellular efficiency. Our method, which we call RNA dactyloscopy, is a reliable tool for assessing the catalytic properties, modeling and design of RNA.
Źródło:
Acta Biochimica Polonica; 2016, 63, 4; 785-787
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Correlated mutations in selected protein families
Autorzy:
Leluk, J.
Sobczyk, M.
Becella, Ł.
Powiązania:
https://bibliotekanauki.pl/articles/1986920.pdf
Data publikacji:
2002
Wydawca:
Politechnika Gdańska
Tematy:
protein sequence
multiple alignment
tertiary structure
mutational correlation
genetic semihomology algorithm
Opis:
Four different protein families (two proteinase inhibitor families, myoglobins and lysozymes) were surveyed for correlated mutations with respect to the position distance and their significance in structure stabilization and biological activity. They were chosen for this study in order to verify the currently admitted model of mutational correlation relationship with respect to spatial contact of the residues and contribution in protein biological activity. There was observed high contribution of spatially dispersed residues (which are also not involved in the protein active center) in mutational correlation. Because of the significantly large distance between correlated positions these cases do not correspond explicitly to any mechanism included in current hypotheses. It is suggested that the role of residue spatial contact in structure preservation, intermolecular interaction and active site rescue mechanisms only partially explains the correlation phenomenon.
Źródło:
TASK Quarterly. Scientific Bulletin of Academic Computer Centre in Gdansk; 2002, 6, 3; 469-482
1428-6394
Pojawia się w:
TASK Quarterly. Scientific Bulletin of Academic Computer Centre in Gdansk
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Structure of small G proteins and their regulators.
Autorzy:
Paduch, Marcin
Jeleń, Filip
Otlewski, Jacek
Powiązania:
https://bibliotekanauki.pl/articles/1043851.pdf
Data publikacji:
2001
Wydawca:
Polskie Towarzystwo Biochemiczne
Tematy:
small G protein
GAP
protein-protein interaction
GTPase
GDI
Rho
Ras
protein tertiary structure
GEF
Opis:
In recent years small G proteins have become an intensively studied group of regulatory GTP hydrolases involved in cell signaling. More than 100 small G proteins have been identified in eucaryotes from protozoan to human. The small G protein superfamily includes Ras, Rho Rab, Rac, Sar1/Arf and Ran homologs, which take part in numerous and diverse cellular processes, such as gene expression, cytoskeleton reorganization, microtubule organization, and vesicular and nuclear transport. These proteins share a common structural core, described as the G domain, and significant sequence similarity. In this paper we review the available data on G domain structure, together with a detailed analysis of the mechanism of action. We also present small G protein regulators: GTPase activating proteins that bind to a catalytic G domain and increase its low intrinsic hydrolase activity, GTPase dissociation inhibitors that stabilize the GDP-bound, inactive state of G proteins, and guanine nucleotide exchange factors that accelerate nucleotide exchange in response to cellular signals. Additionally, in this paper we describe some aspects of small G protein interactions with downstream effectors.
Źródło:
Acta Biochimica Polonica; 2001, 48, 4; 829-850
0001-527X
Pojawia się w:
Acta Biochimica Polonica
Dostawca treści:
Biblioteka Nauki
Artykuł
Tytuł:
Charakterystyka geomorfologiczna obszaru położonego wzdłuż Doliny Środkowej Noteci
Autorzy:
Ratajczak-Szczerba, M.
Powiązania:
https://bibliotekanauki.pl/articles/294966.pdf
Data publikacji:
2011
Wydawca:
Stowarzyszenie Geomorfologów Polskich
Tematy:
geological structure
geomorphology
relief
Tertiary deposits
Quaternary deposits
end moraine
Wyrzysk oscillation
Opis:
The investigated area is located along the Noteć Middle Valley and is situated on the border of several physical-geographical and geomorphologic units. There are according to Krygowski (2000): the Noteć Middle Valley, the Gwda Valley, the Wałcz Lake District, the Kraina Lake District, the Chodzież Lake District. Varied geological structure and the relief of the area. The expression of dynamic activity of the last Scandinavian ice sheet are impressive ladforms like end moraine hills of the Chodzież subphase, the Wyrzysk oscillation, glacial gully, outwash levels.
Źródło:
Landform Analysis; 2011, 16; 99-106
1429-799X
Pojawia się w:
Landform Analysis
Dostawca treści:
Biblioteka Nauki
Artykuł
    Wyświetlanie 1-5 z 5

    Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies