Temat: chromosomal aberrations - Katalog OPAC zbiorów

Skocz do pozycji: 1.

Tytuł:: Assessment of DNA damage using chromosomal aberrations assay in lymphocytes of waterpipe smokers
Autorzy:: Alsatari, Enas S.
Azab, Mohammad
Khabour, Omar F.
Alzoubi, Karem H.
Sadiq, May F.
Powiązania:: https://bibliotekanauki.pl/articles/2180083.pdf
Data publikacji:: 2012-06-01
Wydawca:: Instytut Medycyny Pracy im. prof. dra Jerzego Nofera w Łodzi
Tematy:: waterpipe
smoking
cigarette
chromosomal aberrations
Opis:: Objectives: The aim of this study was to investigate the genotoxicity of waterpipe smoking in the lymphocytes of waterpipe smokers using chromosomal aberrations (CAs) assay. Materials and Methods: Fifty waterpipe smokers and 18 healthy nonsmokers volunteered to participate in the study. Additionally, 18 heavy cigarette smokers were recruited for comparison. Chromosomal aberrations (CAs) assay was used to evaluate DNA damage in the lymphocytes. Results: The results showed that similarly to cigarette smoking, waterpipe smoking significantly increased the frequencies of CAs (p < 0.01). In addition, the frequencies of CAs increased with more waterpipe use. Conclusions: Waterpipe smoking causes DNA damage to lymphocytes and the damage increases with more waterpipe use.
Źródło:: International Journal of Occupational Medicine and Environmental Health; 2012, 25, 3; 218-224
1232-1087
1896-494X
Pojawia się w:: International Journal of Occupational Medicine and Environmental Health
Dostawca treści:: Biblioteka Nauki

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Skocz do pozycji: 2.

Tytuł:: Estimation of cytogenetic risk among coke oven workers exposed to polycyclic aromatic hydrocarbons
Autorzy:: Sureshkumar, Shanmugam
Balachandar, Vellingiri
Devi, Subramaniam
Arun, Meyyazhagan
Karthickkumar, Alagamuthu
Balamuralikrishnan, Balasubramanian
Sankar, Kathannan
Mustaqahamed, Shafi
Dharwadkar, Shanwaz
Sasikala, Keshavarao
Cho, Ssang-Goo
Powiązania:: https://bibliotekanauki.pl/articles/1039534.pdf
Data publikacji:: 2013
Wydawca:: Polskie Towarzystwo Biochemiczne
Tematy:: polycyclic aromatic hydrocarbons (PAHs)
coke oven workers
chromosomal aberrations (CA)
micronucleus (MN)
XRCC1
Opis:: Polycyclic aromatic hydrocarbons (PAHs) result from the incomplete combustion of natural or synthetic organic materials. The working environment at a coke plant can negatively affect the employed workers who were exposed to coke oven emissions containing PAHs, which formed and released into the environment by the process of pyrolysis of coke. This study aims to analyze the relationship between the exposure of PAHs and the risk of genetic damages such as chromosomal alteration (CA), micronucleus (MN), and DNA damage (PCR-RFLP) in peripheral blood lymphocytes of 27 coke oven workers and equal number of control subjects. The exposed subjects and controls were divided into two groups based on their age (group I<35 years and group II ≥35 years). The exposed subjects were further classified into two groups based on the exposure period (<12 years and ≥12 years). The frequencies of CA and MN in exposed subjects are relatively high with respect to controls. The XRCC1 399 Arg/gln polymorphism showed a substantial smaller difference in allele frequencies between exposed and control subjects. Based on present data, it was concluded that coke oven workers under risk should be monitored for adverse effects of the any long-term exposure.
Źródło:: Acta Biochimica Polonica; 2013, 60, 3; 375-379
0001-527X
Pojawia się w:: Acta Biochimica Polonica
Dostawca treści:: Biblioteka Nauki

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