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    Wyświetlanie 1-9 z 9
    Tytuł:
    Estimation of internal distribution of temperature inside biological tissues by means of multifrequency microwave thermograph
    Autorzy:
    Stec, B.
    Dobrowolski, A.
    Powiązania:
    https://bibliotekanauki.pl/articles/308150.pdf
    Data publikacji:
    2002
    Wydawca:
    Instytut Łączności - Państwowy Instytut Badawczy
    Tematy:
    microwave thermograph
    radiometer
    thermal radiation
    breast carcinoma
    Opis:
    The paper presents problems connected with thermal radiation of human bodies in microwave range in aspect of diagnosis breast carcinoma. A mathematical model of transmission thermal radiation through tissues is introduced and methods of measurement of temperature, depth and size of heat source, by means of multifrequency microwave thermograph [1 - 7], are described. Theoretical considerations are supplemented with presentation of result experiments.
    Źródło:
    Journal of Telecommunications and Information Technology; 2002, 1; 39-42
    1509-4553
    1899-8852
    Pojawia się w:
    Journal of Telecommunications and Information Technology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Rak sitowaty imitujący ropień piersi – opis przypadku. Postępowanie diagnostyczno‑terapeutyczne
    Cribriform carcinoma mimicking breast abscess – case report. Diagnostic and therapeutic management
    Autorzy:
    Dobruch‑Sobczak, Katarzyna
    Roszkowska‑Purska, Katarzyna
    Chrapowicki, Eryk
    Powiązania:
    https://bibliotekanauki.pl/articles/1059119.pdf
    Data publikacji:
    2013
    Wydawca:
    Medical Communications
    Tematy:
    breast abscess
    breast carcinoma
    breast sonoelastography
    cribriform breast carcinoma
    histopathological examination
    sonography
    badanie histopatologiczne
    rak piersi
    rak sitowaty piersi
    ropień piersi
    sonoelastografia piersi
    ultrasonografia
    Opis:
    The authors presents a case of cribriform breast carcinoma in a cyst that clinically imitated an abscess. The case concerns a 71-year-old female patient treated for ankylosing spondylitis, with a positive family history of breast cancer. The patient presented at the surgical clinic for incision of an abscess of the mammary gland localized in the lower inner quadrant that was a consequence of previous trauma to the right breast. The abscess was incised and the serosanguineous contents were evacuated. The wound was drained and antibiotics (Dalacin with Metronidazol) were administered for the period of 10 days. During the treatment, a cutaneous fistula was formed. At the incision site, a hard thickening was palpable (tumor). Core needle biopsy of the clinically palpable tumor was performed and the purulent material from the fistula was collected for a culture test. Complete blood count did not reveal leucocytosis. In accordance with the obtained sensitivity report, the patient was started on antibiotics again. Breast ultrasound performed upon the completion of the antibiotic therapy, in the right breast, revealed two solidcystic oval lesions with thick echogenic walls and blurred margins. Both masses contained dense levels of fluid material and solid polycyclic structures. On sonoelastography, the lesions were heterogeneous with a high Young’s modulus. In the right axillary fossa, ultrasound examination revealed three abnormal lymph nodes enlarged to 31 mm length, which were rounded, hypoechoic and without visible sinuses. Histopathology of the core needle biopsy performed at admittance and after the antibiotic therapy indicated a breast abscess (presence of fibrinous and partly fibrinopurulent material). The mass was finally resected to confirm histopathology. The resected material revealed the presence of an invasive, moderately differentiated cribriform carcinoma, which developed within a cyst, with a 40% necrotic component. Eighteen months after the commencement of treatment, the patient remains under oncological supervision and continues hormonal therapy. There are no signs of relapse or foci of distant metastases. The occurrence of breast carcinoma within an abscess emphasises the need for comprehensive assessment and correlation of the clinical picture with imaging and histopathological findings. It also highlights the necessity to include breast abscess in the differential diagnosis of rare forms of carcinomas.
    Przedstawiono przypadek raka sitowatego piersi w torbieli klinicznie imitujący ropień. Dotyczy on 71‑letniej pacjentki leczonej z powodu zesztywniającego zapalenia stawów kręgosłupa, obciążonej rodzinnie rakiem piersi. Kobieta zgłosiła się do poradni chirurgicznej w celu nacięcia ropnia gruczołu piersiowego, zlokalizowanego w kwadrancie dolnym wewnętrznym, który powstał w następstwie urazu prawej piersi. Nacięto ropień, ewakuując treść surowiczo‑krwistą. Ranę zdrenowano oraz włączono antybiotykoterapię (Dalacin z Metronidazolem) na okres 10 dni. W trakcie leczenia doszło do powstania przetoki skórnej. W miejscu po nacięciu ropnia było wyczuwalne twarde zgrubienie (guz). Wykonano biopsję gruboigłową klinicznie wyczuwalnego guza oraz pobrano treść ropną z przetoki na posiew. W badaniu morfologii krwi nie występowała leukocytoza. Włączono ponownie antybiotykoterapię zgodnie z otrzymanym antybiogramem. W badaniu ultrasonograficznym piersi, wykonanym po zakończonej antybiotykoterapii, w prawej piersi uwidoczniono dwie lito‑płynowe owalne zmiany, z obecnością grubych echogennych ścian, o zatartych brzegach. W obu zmianach występowały poziomy zagęszczonej treści płynowej oraz lite struktury o policyklicznych kształtach. W sonoelastografii oceniane zmiany były heterogenne, o wysokich wartościach modułu Younga. W prawym dole pachowym w badaniu ultrasonograficznym stwierdzono trzy nieprawidłowe węzły chłonne, powiększone do 31 mm długości, zaokrąglone, hipoechogeniczne, bez widocznych zatok. Wynik badania histopatologicznego z biopsji gruboigłowej wykonanej przy przyjęciu oraz po zakończonej antybiotykoterapii wskazywał na ropień piersi (opisano obecność mas włóknikowych, częściowo włóknikowo‑ropnych). Dopiero wycięcie całej zmiany celem weryfikacji histopatologicznej ujawniło obecność inwazyjnego, średnio dojrzałego raka sitowatego, który rozwinął się w świetle torbieli, z obszarami martwicy obejmującej około 40% masy guza. Pacjentka po 18 miesiącach od rozpoczęcia leczenia pozostaje pod opieką onkologiczną, kontynuuje hormonoterapię, nie ma nawrotu choroby oraz ognisk przerzutów odległych. Opisany przypadek raka piersi w ropniu wskazuje na potrzebę kompleksowej oceny i korelacji obrazu klinicznego z wynikami badań obrazowych oraz histopatologicznych, a także uwzględniania w diagnostyce różnicowej ropnia piersi rzadko występujących postaci raka.
    Źródło:
    Journal of Ultrasonography; 2013, 13, 53; 222-229
    2451-070X
    Pojawia się w:
    Journal of Ultrasonography
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Multifrequency microwave thermograph for biomedical applications
    Autorzy:
    Stec, B.
    Dobrowolski, A.
    Susek, W.
    Powiązania:
    https://bibliotekanauki.pl/articles/308202.pdf
    Data publikacji:
    2004
    Wydawca:
    Instytut Łączności - Państwowy Instytut Badawczy
    Tematy:
    termografia mikrofalowa
    radiometr
    promieniowanie termiczne
    microwave thermograph
    radiometer
    thermal radiation
    breast carcinoma
    Opis:
    This paper presents problems related to thermal radiation of human bodies in microwave range in aspect of diagnosis of breast carcinoma. A mathematical model of thermal radiation transfer through tissues is introduced and methods of measurement of temperature, depth and size of a heat source, by means of multifrequency microwave thermography are described. Theoretical considerations are supplemented by presentation of experimental results.
    Źródło:
    Journal of Telecommunications and Information Technology; 2004, 1; 117-122
    1509-4553
    1899-8852
    Pojawia się w:
    Journal of Telecommunications and Information Technology
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Tumor Anti-Initiation and Anti-Progression Properties of Sulphated-Extract of Colocasia esculenta
    Autorzy:
    Gamal-Eldeen, Amira M.
    Amer, Hassan
    Fahmy, Cinderella A.
    Dahlawi, Haytham
    Elesawy, Basem H.
    Faizo, Nahla L.
    Raafat, Bassem M.
    Powiązania:
    https://bibliotekanauki.pl/articles/2015590.pdf
    Data publikacji:
    2021-12-01
    Wydawca:
    Instytut Rozrodu Zwierząt i Badań Żywności Polskiej Akademii Nauk w Olsztynie
    Tematy:
    Colocasia esculenta
    CYP1A
    cancer chemoprevention & tumor anti-initiating
    HDAC
    macrophage function
    breast MCF-7 carcinoma
    Opis:
    Colocasia esculenta (Taro) is an edible tuberous plant; however, corms are its most worldwide consumed part while the corm powder is widely used in food industries. In this work, a sulphated polysaccharide extract of C. esculenta corm (SCE) was prepared and its cancer chemopreventive properties was explored. The amending of carcinogen metabolism and radical scavenging affinity revealed that SCE is a strong tumor anti-initiation agent via suppressing cytochrome P450-1A and enhancing glutathione and the carcinogen detoxification enzyme; glutathione S-transferase. SCE exhibited a strong scavenging affinity towards critical radicals (hydroxyl and peroxyl). It induced lymphocyte growth and modulated the macrophage functions into an anti-inflammatory profile, via elevating macrophage proliferation and its binding affinity of fluorescein isothiocyanate-lipopolysaccharide (FITC-LPS) and inhibiting nitric oxide and tumor necrosis factor-α generation. Furthermore, SCE showed a potent cytotoxicity against human breast MCF-7 carcinoma cells (IC50 27.73 µg/mL), whereas SCE treatment inhibited the activity of histone deacetylase (HDAC IC50 37.70 µg/mL) and disturbed the pattern of cell cycle phases. An arrest in both S- and G2/M-phases was linked with shifted cell populations towards late apoptosis and necrosis, as detected by flow cytometry. SCE is a promising cancer chemopreventive agent to be used in healthy food industries and for high breast cancer-risk population.
    Źródło:
    Polish Journal of Food and Nutrition Sciences; 2021, 71, 4; 393-401
    1230-0322
    2083-6007
    Pojawia się w:
    Polish Journal of Food and Nutrition Sciences
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    The use of imaging tests to obtain optimal margins in breast surgery
    Autorzy:
    Ostańska, Elżbieta
    Bartusik-Aebisher, Dorota
    Gustalik, Joanna
    Aebisher, David
    Galiniak, Sabina
    Kaznowska, Ewa
    Powiązania:
    https://bibliotekanauki.pl/articles/1597322.pdf
    Data publikacji:
    2019
    Wydawca:
    Uniwersytet Rzeszowski. Wydawnictwo Uniwersytetu Rzeszowskiego
    Tematy:
    breast conserving surgery
    ductal carcinoma in situ
    extensive itraductal component invasive breast cancer
    lobular carcinoma in situ
    Opis:
    Introduction. The proper negative margins (R0) breadth in the breast - conserving surgery for invasive breast cancer (IBC) and ductal carcinoma in situ (DCIS) is very important. The presence positive surgical margins (R1) is associated with the necessity of reoperation. It delays the adjuvant therapy and psychologically burdens the patient. The re-operation increases the costs of treatment. The introduction of mammography (MMG) increased detection of DCIS by 20%. With the increase in malignancy, cancer detection decreases in MMG, inversely in MRI groving. Effective preoperative and intraoperative diagnosis aims to reduce the number of R1 resections. Aim. The size of the tumor next to its biology, determines the clinical course of the tumor. The accurate analysis of imaging tests is important. Material and methods. This analysis was performed using a systematic literature search. Results. Adequate surgical margins in breast cancer surgery for breast cancer have been reviewed. It is important to know if the cancer is multifocal and what the extent of the tumor is. Conclusion. The adequacy of margins is important for adjusting the volume of excision. It is avoiding unnecessary resection of healthy breast tissue. It is essential for a good cosmetic result and the local recurrence rate. The combination of breast MRI with conventional breast imaging resulted in the lover rate of the R1 resectios and the lower rate of the re-operation.
    Źródło:
    European Journal of Clinical and Experimental Medicine; 2019, 3; 246-249
    2544-2406
    2544-1361
    Pojawia się w:
    European Journal of Clinical and Experimental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Neuroendocrine carcinoma of the mammary gland. A case report of synchronous occurrence of two different carcinomas in one breast
    Neuroendokrynny rak gruczołu piersiowego. Opis przypadku jednoczesnego występowania dwóch różnych raków w tej samej piersi
    Autorzy:
    Lorek, Andrzej J.
    Boratyn-Nowicka, Agnieszka
    Powiązania:
    https://bibliotekanauki.pl/articles/1035730.pdf
    Data publikacji:
    2018
    Wydawca:
    Śląski Uniwersytet Medyczny w Katowicach
    Tematy:
    breast cancer
    imaging
    neuroendocrine carcinoma
    rak piersi
    diagnostyka
    rak neuroendokrynny
    Opis:
    The paper presents a case of primary neuroendocrine breast carcinoma that coexisted with a typical infiltrating carcinoma (BC) within the same mammary gland. It was diagnosed post-operatively on histopathological examination and confirmed by immunohistochemical analysis.
    W pracy przedstawiono przypadek pierwotnego neuroendokrynnego raka piersi, który współwystępował z typowym rakiem naciekającym (BC) w tym samym gruczole piersiowym. Został zdiagnozowany pooperacyjnie w badaniu histopatologicznym i potwierdzony w badaniach immunohistochemicznych.
    Źródło:
    Annales Academiae Medicae Silesiensis; 2018, 72; 252-256
    1734-025X
    Pojawia się w:
    Annales Academiae Medicae Silesiensis
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Overtreatment in surgery – does it concern also the patients with ductal breast carcinoma in situ
    Autorzy:
    Nowikiewicz, Tomasz
    Zegarski, Wojciech
    Głowacka-Mrotek, Iwona
    Powiązania:
    https://bibliotekanauki.pl/articles/1392549.pdf
    Data publikacji:
    2018
    Wydawca:
    Index Copernicus International
    Tematy:
    overtreatment
    overdiagnosis
    surgical treatment
    breast cancer
    ductal carcinoma in situ
    Opis:
    Overtreatment means treatment that goes beyond current standards, and patients with any disease can be overtreated. Overtreatment is also given to patients with cancer, including those who need surgery. Overtreatment is closely related to the problem of overdiagnosis. In patients with cancer, unnecessary surgery may cause complications and generates unnecessary costs. The size of the problem of unnecessary surgery in patients with cancer can best be shown among patients with the most common cancers, which dedicated screening programs. Breast cancer patients, particularly those with pre-invasive types of the tumor, who typically have ductal carcinoma in situ (80%), are likely to undergo unnecessary surgery. We describe the most common clinical problems caused by overtreating patients with ductal carcinoma in situ.
    Źródło:
    Polish Journal of Surgery; 2018, 90, 1; 47-51
    0032-373X
    2299-2847
    Pojawia się w:
    Polish Journal of Surgery
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    αB-crystallin as a promising target in pathological conditions - a review
    Autorzy:
    Maksymiuk, M.
    Sabiborowicz, A.
    Tuzimek, A.
    Deptała, A.
    Czerw, A.
    Badowska-Kozakiewicz, A.M.
    Powiązania:
    https://bibliotekanauki.pl/articles/2086060.pdf
    Data publikacji:
    2020
    Wydawca:
    Instytut Medycyny Wsi
    Tematy:
    αB-crystallin
    small heat-shock proteins
    breast cancer
    renal cell carcinoma
    Opis:
    Introduction and objective. αB-crystallin belongs to the ubiquitous family of small heat-shock proteins. It was discovered as a physiological protein of the eye lens, maintaining its liquid-like property. Furthermore, αB-crystallin was proved to playa bipolar role in both physiological and pathophysiological conditions. This review discusses current knowledge about the biology and genetics of αB-crystallin, and summarizes recent advances in understanding its role in ophthalmic and neurological disorders, as well as breast cancer, renal cancer and other malignancies. State of knowledge. α-crystallins are established as important elements of the protein quality control network, and consequently their defects are related to multiple human diseases. New studies highlight αB-crystallin’s involvement in proliferative diabetic retinopathy angiogenesis and point out its therapeutic potential in age-related macular degeneration. αB-crystallin is thought to be associated with the disease-causing protein aggregates, leading to its connection with such neurological disturbances as anaplastic astrocytoma, Parkinson disease, aging deficits in the peripheral nervous system and multiple sclerosis. In breast cancer, it was proven to be a marker of aggressive behaviur and cerebral metastases. Strong expression of αB-crystallin promoted growth and migration of clear cell renal cell carcinoma cells and was correlated with lower overall survival rate. Considering other malignancies, its various roles were established in colorectal and gastric cancers, head and neck squamous cell carcinomas and osteosarcomas. Conclusions. Further studies concerning αB-crystallin seem to be enormously promising, as they might improve our understanding of common human pathologies as well as contemporary diagnostics and treatment.
    Źródło:
    Annals of Agricultural and Environmental Medicine; 2020, 27, 3; 326-334
    1232-1966
    Pojawia się w:
    Annals of Agricultural and Environmental Medicine
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
    Tytuł:
    Clinical Significance of Van Nuys Prognostic Index As A Qualification Criterion to Sentinel Lymph Node Biopsy in Patients Diagnosed with Ductal Carcinoma in Situ
    Autorzy:
    Nowikiewicz, Tomasz
    Wiśniewska, Magdalena
    Wiśniewski, Michał
    Zegarski, Wojciech
    Powiązania:
    https://bibliotekanauki.pl/articles/1395856.pdf
    Data publikacji:
    2015-02-03
    Wydawca:
    Index Copernicus International
    Tematy:
    breast cancer
    ductal carcinoma in situ
    sentinel lymph node biosy
    Van Nuys Prognostic Index
    surgical treatment
    Opis:
    Diagnose of ductal carcinoma in situ (DCIS) requires, at least in a part of cases, assessment of auxiliary lymph nodes. The aim of the study was to analyze clinical value of Van Nuys Prognostic Index (VNPI) as the important criterion for qualification of DCIS patients to sentinel lymph node biopsy (SLNB). Material and methods. Analysis included patients diagnosed with DCIS and qualified to SLNB, operated in years 2004-2013. We performed a statistical analysis to assess correlation between VNPI value and positive pathological verification of excised sentinel lymph node (SLN). The influence of other clinical factors on presence of metastases in SLN was also determined. Results. 3,6% of DCIS patients were diagnosed with metastases in SLN. Metastases were diagnosed in 6.7% patients with VNPI > 10 points vs 3.4% in patients with VNPI < 10 points. In 75% of patients with metastatic SLN the value of VNPI was at least 10 points. In premenopausal patients metastases in SLN were diagnosed in 8.1% of cases vs 1.4% in postmenopausal patients. In patients diagnosed with cancer of the other breast metastases in SLN were found in 6.3% of cases vs 3.2% in one-sided cancer. Patients with multifocal cancer were over twice as often diagnosed with metastases in SLN (5% vs 2%). There was no correlation found between VNPI value and positive pathological verification of SLN. No differences between prevalence of SLN metastases depending on selected clinical features were found. Conclusions. Recommendation of VNPI as the criterion of qualification to SLNB starting with 10 points could be more favourable in patients with DCIS. Deciding on SLNB in DCIS patients, we should also take into consideration other clinical features.
    Źródło:
    Polish Journal of Surgery; 2014, 86, 10; 479-485
    0032-373X
    2299-2847
    Pojawia się w:
    Polish Journal of Surgery
    Dostawca treści:
    Biblioteka Nauki
    Artykuł
      Wyświetlanie 1-9 z 9

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